ES8606240A1 - Semiesteres pentanodioicos 3-sustituidos - Google Patents

Semiesteres pentanodioicos 3-sustituidos

Info

Publication number
ES8606240A1
ES8606240A1 ES539398A ES539398A ES8606240A1 ES 8606240 A1 ES8606240 A1 ES 8606240A1 ES 539398 A ES539398 A ES 539398A ES 539398 A ES539398 A ES 539398A ES 8606240 A1 ES8606240 A1 ES 8606240A1
Authority
ES
Spain
Prior art keywords
hydroxypentanedioic
hemiesters
anhydrides
acids
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES539398A
Other languages
English (en)
Other versions
ES539398A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GD Searle LLC
Original Assignee
GD Searle LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GD Searle LLC filed Critical GD Searle LLC
Publication of ES539398A0 publication Critical patent/ES539398A0/es
Publication of ES8606240A1 publication Critical patent/ES8606240A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/235—Saturated compounds containing more than one carboxyl group
    • C07C59/245—Saturated compounds containing more than one carboxyl group containing hydroxy or O-metal groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C31/00—Saturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C31/02—Monohydroxylic acyclic alcohols
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/02—Acyclic alcohols with carbon-to-carbon double bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C07C45/29—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups
    • C07C45/292—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups with chromium derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/02—Saturated compounds having —CHO groups bound to acyclic carbon atoms or to hydrogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C07C57/03—Monocarboxylic acids

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR SEMIESTERES PENTANODIOICOS 3-SUSTITUIDOS. COMPRENDE: A) TRATAR A UN C.D.F. (II) CON CLORURO DE TIONILO, EN METANOL, PARA DAR UN C.D.F. (III); B) HIDROGENAR A (III), PARA CONSEGUIR UN C.D.F. (IV); C) SOMETER A UNA REACCION DE GRIGNARD A (IV), PARA DAR UN C.D.F. (V); D) OZONOLIZAR A (V) CON OZONO Y AGUA OXIGENADA, PARA PRODUCIR UN C.D.F. (VI); E) CONDENSAR A (VI), PARA CONSEGUIR UN C.D.F. (VII) Y F) HIDROGENAR A (VII), PARA OBTENER A UN C.D.F. (I). SIENDO: R1 TER-BUTILO; R2 H; R3 CH2CO2R5; R4 CH2CO2H Y R5 H, ALQUILO DE C 1 A 6. SE UTILIZAN EN LA PREVENCION O TRATAMIENTO DE ESTADOS ENFERMIZOS CAUSADOS POR LA ACCION DEGRADATIVA DE PROTEASAS SOBRE ELASTINA DE MAMIFEROS.
ES539398A 1984-01-09 1985-01-08 Semiesteres pentanodioicos 3-sustituidos Expired ES8606240A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/569,007 US4554359A (en) 1984-01-09 1984-01-09 3-Substituted pentanedioic acids and derivatives thereof

Publications (2)

Publication Number Publication Date
ES539398A0 ES539398A0 (es) 1986-04-01
ES8606240A1 true ES8606240A1 (es) 1986-04-01

Family

ID=24273704

Family Applications (1)

Application Number Title Priority Date Filing Date
ES539398A Expired ES8606240A1 (es) 1984-01-09 1985-01-08 Semiesteres pentanodioicos 3-sustituidos

Country Status (7)

Country Link
US (1) US4554359A (es)
EP (1) EP0156100B1 (es)
JP (1) JPS60208943A (es)
AU (1) AU578923B2 (es)
DE (1) DE3574965D1 (es)
ES (1) ES8606240A1 (es)
ZA (1) ZA85176B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4645858A (en) * 1982-03-22 1987-02-24 G. D. Searle & Co. Pentanedioic acid derivatives
US5055613A (en) * 1988-02-18 1991-10-08 G. D. Searle & Co. Metabolites of pentanedioic acid derivatives
WO1999047104A1 (en) * 1998-03-17 1999-09-23 Jeneric Pentron Incorporated Dental bridges comprising fiber reinforced frameworks
WO2004071327A1 (en) * 2003-02-06 2004-08-26 Pentron Clinical Technologies, Llc Method of manufacturing dental posts, obturators and restorations

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3818080A (en) * 1972-07-20 1974-06-18 Searle & Co 3-hydroxy-3-substituted glutaric acid derivatives
DK162713C (da) * 1982-03-22 1992-04-21 Searle & Co Analogifremgangsmaade til fremstilling af 3-hydroxyglutarsyrederivater

Also Published As

Publication number Publication date
AU3738985A (en) 1985-07-18
AU578923B2 (en) 1988-11-10
ES539398A0 (es) 1986-04-01
US4554359A (en) 1985-11-19
EP0156100A2 (en) 1985-10-02
EP0156100B1 (en) 1989-12-27
JPS60208943A (ja) 1985-10-21
ZA85176B (en) 1986-02-26
DE3574965D1 (de) 1990-02-01
EP0156100A3 (en) 1986-06-25

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