DK2289527T3 - BIFIDOBACTERIUM LONGUM AND FUNCTIONAL GI DISEASES - Google Patents

BIFIDOBACTERIUM LONGUM AND FUNCTIONAL GI DISEASES Download PDF

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Publication number
DK2289527T3
DK2289527T3 DK09168590.9T DK09168590T DK2289527T3 DK 2289527 T3 DK2289527 T3 DK 2289527T3 DK 09168590 T DK09168590 T DK 09168590T DK 2289527 T3 DK2289527 T3 DK 2289527T3
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Prior art keywords
composition
functional
bifidobacterium longum
atcc baa
composition according
Prior art date
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DK09168590.9T
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Danish (da)
English (en)
Inventor
Peter Mclean
Degonda Gabriela Bergonzelli
Stephen Michael Collins
Premysl Bercik
De Bercik Elena Verdu
Original Assignee
Nestec Sa
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Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41508246&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK2289527(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Nestec Sa filed Critical Nestec Sa
Application granted granted Critical
Publication of DK2289527T3 publication Critical patent/DK2289527T3/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/745Bifidobacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/10Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/16Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
    • A23K10/18Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/135Bacteria or derivatives thereof, e.g. probiotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/702Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/01Hydrolysed proteins; Derivatives thereof
    • A61K38/012Hydrolysed proteins; Derivatives thereof from animals
    • A61K38/018Hydrolysed proteins; Derivatives thereof from animals from milk
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10Laxatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/163Sugars; Polysaccharides
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/20Reducing nutritive value; Dietetic products with reduced nutritive value
    • A23L33/21Addition of substantially indigestible substances, e.g. dietary fibres
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2400/00Lactic or propionic acid bacteria
    • A23V2400/51Bifidobacterium
    • A23V2400/533Longum

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Mycology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Polymers & Plastics (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Nutrition Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Physiology (AREA)
  • Animal Husbandry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK09168590.9T 2009-08-25 2009-08-25 BIFIDOBACTERIUM LONGUM AND FUNCTIONAL GI DISEASES DK2289527T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP09168590.9A EP2289527B1 (en) 2009-08-25 2009-08-25 Bifidobacterium longum and functional GI disorders

Publications (1)

Publication Number Publication Date
DK2289527T3 true DK2289527T3 (en) 2018-04-23

Family

ID=41508246

Family Applications (1)

Application Number Title Priority Date Filing Date
DK09168590.9T DK2289527T3 (en) 2009-08-25 2009-08-25 BIFIDOBACTERIUM LONGUM AND FUNCTIONAL GI DISEASES

Country Status (17)

Country Link
US (3) US10028981B2 (cg-RX-API-DMAC7.html)
EP (2) EP2289527B1 (cg-RX-API-DMAC7.html)
JP (4) JP2013503130A (cg-RX-API-DMAC7.html)
CN (2) CN106072658A (cg-RX-API-DMAC7.html)
AU (1) AU2010288546B2 (cg-RX-API-DMAC7.html)
BR (1) BR112012004046B1 (cg-RX-API-DMAC7.html)
CA (1) CA2772163C (cg-RX-API-DMAC7.html)
CL (1) CL2012000487A1 (cg-RX-API-DMAC7.html)
DK (1) DK2289527T3 (cg-RX-API-DMAC7.html)
ES (1) ES2664828T3 (cg-RX-API-DMAC7.html)
IN (1) IN2012DN01638A (cg-RX-API-DMAC7.html)
MX (1) MX2012002402A (cg-RX-API-DMAC7.html)
RU (1) RU2012111253A (cg-RX-API-DMAC7.html)
SG (1) SG178499A1 (cg-RX-API-DMAC7.html)
TR (1) TR201807143T4 (cg-RX-API-DMAC7.html)
WO (1) WO2011023689A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA201202155B (cg-RX-API-DMAC7.html)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2110028A1 (en) 2008-04-15 2009-10-21 Nestec S.A. Bifidobacterium longum and hippocampal BDNF expression
EP2289527B1 (en) 2009-08-25 2018-02-21 Nestec S.A. Bifidobacterium longum and functional GI disorders
EP2452576A1 (en) * 2010-11-11 2012-05-16 Nestec S.A. Extruded non-replicating probiotic micro-organisms and their health benefits
US9173910B2 (en) 2012-02-29 2015-11-03 The General Hospital Corporation Compositions of microbiota and methods related thereto
US11179427B2 (en) 2013-01-21 2021-11-23 Eth Zurich Baby food composition comprising viable propionic acid-producing bacteria
US10633714B2 (en) 2013-07-21 2020-04-28 Pendulum Therapeutics, Inc. Methods and systems for microbiome characterization, monitoring and treatment
US20150305385A1 (en) * 2014-04-25 2015-10-29 Mead Johnson Nutrition Company Pediatric nutritional composition with human milk oligosaccahrides, prebiotics and probiotics
GB2551642B (en) 2014-10-31 2020-09-23 Pendulum Therapeutics Inc Methods and compositions relating to microbial treatment and diagnosis of disorders
WO2016183535A1 (en) 2015-05-14 2016-11-17 University Of Puerto Rico Methods for restoring microbiota of newborns
CA2983685A1 (en) 2015-06-11 2016-12-15 Nestec S.A. Dietary supplement comprising a probiotic and ferric pyrophosphate
CA2994345A1 (en) * 2015-08-31 2017-03-09 Nestec S.A. Methods and compositions using bifidobacterium longum to treat or prevent depressive symptoms
CN108243603A (zh) * 2015-08-31 2018-07-03 雀巢产品技术援助有限公司 使用长双歧杆菌调节情绪反应性并治疗或预防亚临床心境紊乱的方法和组合物
MX2018002032A (es) * 2015-08-31 2018-04-13 Nestec Sa Metodos y composiciones que usan bifidobacterium longum para optimizar la lactancia materna.
US10780103B2 (en) 2015-10-28 2020-09-22 Glycom A/S Synthetic composition and method for modulating emotion and mood disorders
US10835545B2 (en) 2015-10-28 2020-11-17 Glycom A/S Synthetic composition and method for modulating brain function and behaviour
WO2017117142A1 (en) 2015-12-28 2017-07-06 New York University Device and method of restoring microbiota of newborns
JP6353478B2 (ja) * 2016-03-28 2018-07-04 日清食品ホールディングス株式会社 セロトニン分泌促進能力を有するビフィズス菌
CN107050062A (zh) * 2016-11-08 2017-08-18 江西益盟科技有限公司 治疗便秘的乳酸菌组合物及其制备方法
CN106579414A (zh) * 2016-12-26 2017-04-26 北京康比特体育科技股份有限公司 一种缓解运动性腹泻的组合物
EP3589726A1 (en) 2017-02-28 2020-01-08 Alimentary Health Limited Bifidobacterium longum able to beneficially modulate immune response to respiratory virus infection
EP3532603B1 (en) * 2017-02-28 2020-09-09 PrecisionBiotics Group Limited Bifidobacterium longum able to beneficially modulate immune response to respiratory virus infection
BR112019020443A2 (pt) * 2017-05-05 2020-04-28 Nestle Sa tratamento de cólica em bebês
AU2018326705A1 (en) 2017-08-30 2020-03-05 Pendulum Therapeutics, Inc. Methods and compositions for treatment of microbiome-associated disorders
JP7280069B2 (ja) 2018-03-28 2023-05-23 森永乳業株式会社 機能性消化管障害予防又は改善用組成物、並びに、該機能性消化管障害予防又は改善用組成物を用いた医薬品組成物及び飲食品組成物
CA3106315A1 (en) 2018-07-19 2020-01-23 Pendulum Therapeutics, Inc. Methods and compositions for microbial engraftment
CN114402062B (zh) * 2019-07-01 2025-02-25 雀巢产品有限公司 产生丝氨酸蛋白酶抑制剂
JP2021014422A (ja) * 2019-07-11 2021-02-12 日清ファルマ株式会社 便性改善剤
JP2021014421A (ja) * 2019-07-11 2021-02-12 日清ファルマ株式会社 Qol改善剤
CN111187734A (zh) * 2019-12-25 2020-05-22 生合生物科技(扬州)有限公司 长双歧杆菌bl986、由其制备的冻干粉及冻干粉的应用
JP7761591B2 (ja) * 2020-05-20 2025-10-28 ソシエテ・デ・プロデュイ・ネスレ・エス・アー ビフィドバクテリウム・ロンガムによる不溶性繊維の発酵性及び短鎖脂肪酸産生の改善

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH637297A5 (fr) 1978-12-05 1983-07-29 Nestle Sa Microbille comprenant un microorganisme et son procede de fabrication.
ID29150A (id) 1999-01-15 2001-08-02 Entpr Ireland Cs Penggunaan lactobacillus salivarius
DE10008279A1 (de) * 2000-02-23 2001-08-30 Meggle Gmbh Milchzucker enthaltende Zusammensetzung
US20020044988A1 (en) * 2000-08-22 2002-04-18 Fuchs Eileen C. Nutritional composition and method for improving protein deposition
PE20030284A1 (es) * 2001-07-26 2003-05-01 Alimentary Health Ltd Cepas de bifidobacterium
EP1429620A1 (en) * 2001-08-31 2004-06-23 Nutricopia, Inc. Nutritional frozen dessert and methods of menufacture
EP1384483A1 (en) 2002-07-23 2004-01-28 Nestec S.A. Probiotics for treatment of irritable bowel disease (IBS) through improvement of gut neuromuscular function
AU2003303894A1 (en) * 2003-01-30 2004-08-30 The Regents Of The University Of California Inactivated probiotic bacteria and methods of use thereof
JP2004262773A (ja) * 2003-02-17 2004-09-24 Ryoshoku Kenkyukai 免疫機能改善を目的としたビフィズス菌製剤
US20040265279A1 (en) 2003-05-08 2004-12-30 Timothy Dinan Probiotics in the treatment of atypical depression and other disorders characterized by hypothalamic pitiuitary-adrenal axis over-activity
CA2532489C (en) * 2003-06-23 2012-12-11 Nestec S.A. Infant or follow-on formula
US20050100559A1 (en) * 2003-11-07 2005-05-12 The Procter & Gamble Company Stabilized compositions comprising a probiotic
US20060093592A1 (en) * 2004-10-04 2006-05-04 Nutracea Synbiotics
US8134942B2 (en) * 2005-08-24 2012-03-13 Avaak, Inc. Communication protocol for low-power network applications and a network of sensors using the same
WO2007054208A1 (en) * 2005-11-14 2007-05-18 Unilever N.V. Edible product containing ginseng polysaccharides and beneficial bacteria
JP2007169200A (ja) * 2005-12-21 2007-07-05 Morinaga Milk Ind Co Ltd インフルエンザ感染予防のための医薬及び飲食品
PH12012500739A1 (en) * 2006-02-15 2013-06-17 Nestec Sa Use of bfidobacterium longum for the prevention and treatment of inflammation
EP1993576B1 (en) 2006-03-07 2015-10-21 Nestec S.A. Synbiotic mixture
EP1961308A1 (en) * 2007-02-21 2008-08-27 Nestec S.A. Nutritionally balanced frozen dessert
EP1974735A1 (en) * 2007-03-28 2008-10-01 Nestec S.A. Reduction of risk of diarrhoea
EP1974743A1 (en) * 2007-03-28 2008-10-01 Nestec S.A. Probiotics to Improve Gut Microbiota
EP2227239A2 (en) * 2007-12-06 2010-09-15 Arla Foods Amba Probiotic bacteria and regulation of fat storage
RU2010129825A (ru) * 2007-12-17 2012-01-27 Юриверсити Оф Флорида Рисерч Фаундейшн, Инк. (Us) Материалы и способы для лечения патологической пролиферации глазных сосудов
EP2110028A1 (en) * 2008-04-15 2009-10-21 Nestec S.A. Bifidobacterium longum and hippocampal BDNF expression
WO2010008272A1 (en) * 2008-07-15 2010-01-21 N.V. Nutricia Treatment of gut motility disorders
EP2289527B1 (en) 2009-08-25 2018-02-21 Nestec S.A. Bifidobacterium longum and functional GI disorders
EP4154722A1 (en) * 2018-01-29 2023-03-29 PrecisionBiotics Group Limited A combination product for prophylaxis and treatment of irritable bowel syndrome

Also Published As

Publication number Publication date
ES2664828T3 (es) 2018-04-23
JP2013503130A (ja) 2013-01-31
SG178499A1 (en) 2012-04-27
EP2289527A1 (en) 2011-03-02
WO2011023689A1 (en) 2011-03-03
JP7096652B6 (ja) 2022-08-01
US11452745B2 (en) 2022-09-27
AU2010288546A1 (en) 2012-03-22
US20220280576A1 (en) 2022-09-08
EP2470188A1 (en) 2012-07-04
BR112012004046A2 (pt) 2017-05-30
ZA201202155B (en) 2014-09-25
US20190134104A1 (en) 2019-05-09
US10028981B2 (en) 2018-07-24
RU2012111253A (ru) 2013-10-10
JP7096652B2 (ja) 2022-07-06
JP2016074682A (ja) 2016-05-12
IN2012DN01638A (cg-RX-API-DMAC7.html) 2015-06-05
CN106072658A (zh) 2016-11-09
CN102573863A (zh) 2012-07-11
CL2012000487A1 (es) 2012-08-31
MX2012002402A (es) 2012-04-02
CA2772163C (en) 2017-11-07
CA2772163A1 (en) 2011-03-03
JP2018048112A (ja) 2018-03-29
US11957720B2 (en) 2024-04-16
US20120230956A1 (en) 2012-09-13
AU2010288546B2 (en) 2015-08-20
BR112012004046B1 (pt) 2021-02-17
TR201807143T4 (tr) 2018-06-21
EP2289527B1 (en) 2018-02-21
JP2020183385A (ja) 2020-11-12

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