DK2280961T3 - 1,5-diphenyl-pyrrolidin-2-on-forbindelser som cb-1-ligander - Google Patents

1,5-diphenyl-pyrrolidin-2-on-forbindelser som cb-1-ligander

Info

Publication number
DK2280961T3
DK2280961T3 DK09734415.4T DK09734415T DK2280961T3 DK 2280961 T3 DK2280961 T3 DK 2280961T3 DK 09734415 T DK09734415 T DK 09734415T DK 2280961 T3 DK2280961 T3 DK 2280961T3
Authority
DK
Denmark
Prior art keywords
pyrrolidin
ligands
diphenyl
compounds
Prior art date
Application number
DK09734415.4T
Other languages
English (en)
Inventor
John Mehnert Schaus
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of DK2280961T3 publication Critical patent/DK2280961T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK09734415.4T 2008-04-22 2009-04-02 1,5-diphenyl-pyrrolidin-2-on-forbindelser som cb-1-ligander DK2280961T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4694308P 2008-04-22 2008-04-22
PCT/US2009/039293 WO2009131815A1 (en) 2008-04-22 2009-04-02 1,5-diphenyl-pyrrolidin-2-one compounds as cb-1 ligands

Publications (1)

Publication Number Publication Date
DK2280961T3 true DK2280961T3 (da) 2012-08-27

Family

ID=40600096

Family Applications (1)

Application Number Title Priority Date Filing Date
DK09734415.4T DK2280961T3 (da) 2008-04-22 2009-04-02 1,5-diphenyl-pyrrolidin-2-on-forbindelser som cb-1-ligander

Country Status (17)

Country Link
US (1) US8420654B2 (da)
EP (1) EP2280961B1 (da)
JP (1) JP5539323B2 (da)
KR (1) KR101283803B1 (da)
CN (1) CN102007121B (da)
AU (1) AU2009238445B2 (da)
BR (1) BRPI0910775A2 (da)
CA (1) CA2721542C (da)
DK (1) DK2280961T3 (da)
EA (1) EA019067B1 (da)
ES (1) ES2390560T3 (da)
HR (1) HRP20120680T1 (da)
MX (1) MX2010011547A (da)
PL (1) PL2280961T3 (da)
PT (1) PT2280961E (da)
SI (1) SI2280961T1 (da)
WO (1) WO2009131815A1 (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10154988B2 (en) 2012-11-14 2018-12-18 The Johns Hopkins University Methods and compositions for treating schizophrenia

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1496838B1 (en) * 2002-03-12 2010-11-03 Merck Sharp & Dohme Corp. Substituted amides
TW200533657A (en) 2004-02-17 2005-10-16 Esteve Labor Dr Substituted pyrazoline compounds, their preparation and use as medicaments
AU2005214084B2 (en) 2004-02-19 2010-06-03 Solvay Pharmaceuticals B.V. Imidazoline derivatives having CB1-antagonistic activity
WO2007020502A2 (en) * 2005-08-16 2007-02-22 Pharmacia & Upjohn Company Llc Cannabinoid receptor ligands and uses thereof
EP2097410A4 (en) * 2006-09-29 2009-11-25 Green Cross Corp HETEROYL-PYRAZOLE DERIVATIVES AS CANNABINOID CB1 RECEPTOR ANTAGONISTS
PE20080926A1 (es) 2006-10-23 2008-07-19 Lilly Co Eli Compuestos cb1

Also Published As

Publication number Publication date
PL2280961T3 (pl) 2012-12-31
ES2390560T3 (es) 2012-11-14
EP2280961A1 (en) 2011-02-09
KR101283803B1 (ko) 2013-07-15
US8420654B2 (en) 2013-04-16
HRP20120680T1 (hr) 2012-10-31
PT2280961E (pt) 2012-09-10
EA019067B1 (ru) 2013-12-30
EP2280961B1 (en) 2012-07-25
CA2721542C (en) 2016-03-29
MX2010011547A (es) 2010-11-09
US20110034484A1 (en) 2011-02-10
CN102007121A (zh) 2011-04-06
AU2009238445B2 (en) 2013-09-26
BRPI0910775A2 (pt) 2015-09-29
WO2009131815A1 (en) 2009-10-29
AU2009238445A1 (en) 2009-10-29
SI2280961T1 (sl) 2012-11-30
CA2721542A1 (en) 2009-10-29
EA201071223A1 (ru) 2011-04-29
JP5539323B2 (ja) 2014-07-02
KR20100124342A (ko) 2010-11-26
CN102007121B (zh) 2013-08-14
JP2011518220A (ja) 2011-06-23

Similar Documents

Publication Publication Date Title
BRPI0923786A2 (pt) compostos 5,6-dihidro-6-fenilbenzo(f) isoquinolina-2- amina substituidos
BRPI0815717A2 (pt) Compostos de imidazopirazina.
ATE555107T1 (de) 2-aza-bicyclo-ä2,2,1-üheptan-derivate
BRPI0821627A2 (pt) Compostos químicos
BRPI0813500A2 (pt) Compostos antivirais
BRPI0821086A2 (pt) Compostos inseticidas
BRPI0814601A2 (pt) compostos químicos
DK2185567T3 (da) Substituerede bicyclolactam-forbindelser
BRPI0920608A2 (pt) compostos quimicos
BRPI0907563A2 (pt) Derivados de 4,5-di-hidro-xazol-2-il amina
DK2288375T3 (da) Pegylerede insulin-lispro-forbindelser
BRPI0920707A2 (pt) compostos
DK2242759T3 (da) Forbindelser
BRPI0816970A2 (pt) 1,3-dissubstituídas-4-fenil-1h-piridin-2-onas
CR10353A (es) Nuevos compuestos.
BRPI0811264A2 (pt) Compostos
BRPI0806689A2 (pt) Compostos químicos 637
DK2205562T3 (da) 1,1,1-trifluor-2-hydroxy-3-phenylpropanderivater
BRPI0814424A2 (pt) Compostos heterociclila
BRPI0809996A2 (pt) Compostos
BRPI0912716A2 (pt) composto.
BRPI0916432A2 (pt) compostos
BRPI0814411A2 (pt) Compostos químicos
BRPI0815181A2 (pt) Compostos
DK2132185T3 (da) Pyrimidinyl-piperaziner nyttige som dopamin-D3/D2-receptorligander