SI2280961T1 - Spojine difenil pirolidin ona kot ligandi cb - Google Patents

Spojine difenil pirolidin ona kot ligandi cb

Info

Publication number
SI2280961T1
SI2280961T1 SI200930349T SI200930349T SI2280961T1 SI 2280961 T1 SI2280961 T1 SI 2280961T1 SI 200930349 T SI200930349 T SI 200930349T SI 200930349 T SI200930349 T SI 200930349T SI 2280961 T1 SI2280961 T1 SI 2280961T1
Authority
SI
Slovenia
Prior art keywords
pyrrolidin
ligands
diphenyl
compounds
Prior art date
Application number
SI200930349T
Other languages
English (en)
Inventor
John Mehnert Schaus
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of SI2280961T1 publication Critical patent/SI2280961T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Hospice & Palliative Care (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
SI200930349T 2008-04-22 2009-04-02 Spojine difenil pirolidin ona kot ligandi cb SI2280961T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4694308P 2008-04-22 2008-04-22
PCT/US2009/039293 WO2009131815A1 (en) 2008-04-22 2009-04-02 1,5-diphenyl-pyrrolidin-2-one compounds as cb-1 ligands
EP09734415A EP2280961B1 (en) 2008-04-22 2009-04-02 1,5-diphenyl-pyrrolidin-2-one compounds as cb-1 ligands

Publications (1)

Publication Number Publication Date
SI2280961T1 true SI2280961T1 (sl) 2012-11-30

Family

ID=40600096

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200930349T SI2280961T1 (sl) 2008-04-22 2009-04-02 Spojine difenil pirolidin ona kot ligandi cb

Country Status (17)

Country Link
US (1) US8420654B2 (sl)
EP (1) EP2280961B1 (sl)
JP (1) JP5539323B2 (sl)
KR (1) KR101283803B1 (sl)
CN (1) CN102007121B (sl)
AU (1) AU2009238445B2 (sl)
BR (1) BRPI0910775A2 (sl)
CA (1) CA2721542C (sl)
DK (1) DK2280961T3 (sl)
EA (1) EA019067B1 (sl)
ES (1) ES2390560T3 (sl)
HR (1) HRP20120680T1 (sl)
MX (1) MX2010011547A (sl)
PL (1) PL2280961T3 (sl)
PT (1) PT2280961E (sl)
SI (1) SI2280961T1 (sl)
WO (1) WO2009131815A1 (sl)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10154988B2 (en) 2012-11-14 2018-12-18 The Johns Hopkins University Methods and compositions for treating schizophrenia

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1496838B1 (en) * 2002-03-12 2010-11-03 Merck Sharp & Dohme Corp. Substituted amides
TW200533657A (en) 2004-02-17 2005-10-16 Esteve Labor Dr Substituted pyrazoline compounds, their preparation and use as medicaments
PT1725536E (pt) 2004-02-19 2009-01-22 Solvay Pharm Bv Derivados de imidazolina apresentando actividade antagonista cb1
WO2007020502A2 (en) * 2005-08-16 2007-02-22 Pharmacia & Upjohn Company Llc Cannabinoid receptor ligands and uses thereof
EP2097410A4 (en) * 2006-09-29 2009-11-25 Green Cross Corp HETEROYL-PYRAZOLE DERIVATIVES AS CANNABINOID CB1 RECEPTOR ANTAGONISTS
TW200825067A (en) 2006-10-23 2008-06-16 Lilly Co Eli CB1 compounds

Also Published As

Publication number Publication date
CA2721542A1 (en) 2009-10-29
CN102007121B (zh) 2013-08-14
US8420654B2 (en) 2013-04-16
PT2280961E (pt) 2012-09-10
KR20100124342A (ko) 2010-11-26
PL2280961T3 (pl) 2012-12-31
AU2009238445A1 (en) 2009-10-29
BRPI0910775A2 (pt) 2015-09-29
JP5539323B2 (ja) 2014-07-02
MX2010011547A (es) 2010-11-09
CA2721542C (en) 2016-03-29
WO2009131815A1 (en) 2009-10-29
US20110034484A1 (en) 2011-02-10
JP2011518220A (ja) 2011-06-23
ES2390560T3 (es) 2012-11-14
EA201071223A1 (ru) 2011-04-29
EP2280961B1 (en) 2012-07-25
HRP20120680T1 (hr) 2012-10-31
DK2280961T3 (da) 2012-08-27
CN102007121A (zh) 2011-04-06
KR101283803B1 (ko) 2013-07-15
AU2009238445B2 (en) 2013-09-26
EA019067B1 (ru) 2013-12-30
EP2280961A1 (en) 2011-02-09

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