DK2271218T3 - USE AND COMPOSITION TO TREAT DEMENS - Google Patents
USE AND COMPOSITION TO TREAT DEMENS Download PDFInfo
- Publication number
- DK2271218T3 DK2271218T3 DK09726036.8T DK09726036T DK2271218T3 DK 2271218 T3 DK2271218 T3 DK 2271218T3 DK 09726036 T DK09726036 T DK 09726036T DK 2271218 T3 DK2271218 T3 DK 2271218T3
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- DK
- Denmark
- Prior art keywords
- pharmaceutically acceptable
- group
- achei
- acceptable salts
- nspacha
- Prior art date
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
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- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Emergency Medicine (AREA)
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- Organic Chemistry (AREA)
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- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| US8969402B2 (en) | 2006-11-15 | 2015-03-03 | Steven A. Rich | Combined acetylcholinesterase inhibitor and quaternary ammonium antimuscarinic therapy to alter progression of cognitive diseases |
| US20110201597A1 (en) | 2008-03-27 | 2011-08-18 | Chase Thomas N | Method and composition for treating alzheimer-type dementia |
| EP4088717A1 (en) * | 2008-03-27 | 2022-11-16 | Chase Pharmaceuticals Corporation | Use and composition for treating dementia |
| ES2742728T3 (es) | 2009-07-22 | 2020-02-17 | PureTech Health LLC | Composiciones para el tratamiento de trastornos mejorados por la activación del receptor muscarínico |
| EP2478099B1 (en) | 2009-09-18 | 2019-06-05 | Chase Pharmaceuticals Corporation | Combination for treating alzheimer-type dementia |
| JP2011213606A (ja) * | 2010-03-31 | 2011-10-27 | Sawai Pharmaceutical Co Ltd | ドネペジルを含有する固形製剤の製造方法 |
| JP2011213695A (ja) * | 2010-04-02 | 2011-10-27 | Taisho Pharm Ind Ltd | ドネペジル塩酸塩含有口腔内速崩壊錠 |
| AU2013312749B2 (en) * | 2012-09-05 | 2018-01-18 | Chase Pharmaceuticals Corporation | Anticholinergic neuroprotective composition and methods |
| US10149828B2 (en) * | 2015-01-09 | 2018-12-11 | Chase Pharmaceuticals Corporation | Oxybutynin transdermal therapeutic system combination |
| EP3265466A4 (en) * | 2015-03-06 | 2018-12-26 | Chase Pharmaceuticals Corporation | Peripheral-anticholinergic muscarinic agonist combination |
| EP3265128A4 (en) | 2015-03-06 | 2018-09-12 | Chase Pharmaceuticals Corporation | Oxybutynin transdermal therapeutic system muscarinic agonist combination |
| US10307409B2 (en) * | 2015-03-06 | 2019-06-04 | Chase Pharmaceuticals Corporation | Muscarinic combinations and their use for combating hypocholinergic disorders of the central nervous system |
| MA43047A (fr) | 2015-06-15 | 2018-08-08 | Qaam Pharmaceuticals Llc | Sels d'acides gras de glycopyrronium et leurs procédés de production |
| US20180360845A1 (en) * | 2015-07-20 | 2018-12-20 | Chase Pharmaceuticals Corporation | Muscarinic combination of a selective m2-antagonist and a peripheral non-selective antagonist for treating hypocholinergic disorders |
| WO2017044693A1 (en) | 2015-09-11 | 2017-03-16 | Chase Pharmaceuticals Corporation | Muscarinic combination and its use for combating hypocholinergic disorders of the central nervous system |
| WO2017147104A1 (en) * | 2016-02-24 | 2017-08-31 | Chase Pharmaceuticals Corporation | Muscarinic m2-antagonist combinations |
| US10479706B2 (en) * | 2016-06-03 | 2019-11-19 | Katz Water Tech, Llc | Apparatus, method and system for desalinating water |
| US20190269627A1 (en) | 2016-10-28 | 2019-09-05 | Chase Pharmaceuticals Corporation | Memantine combinations and use |
| JP2021522187A (ja) * | 2018-04-17 | 2021-08-30 | エルテーエス ローマン テラピー−ジステーメ アーゲー | ソリフェナシンの経皮投与のための経皮治療システム |
| PT3856182T (pt) | 2018-09-28 | 2026-03-10 | Karuna Therapeutics Inc | Composições e métodos para o tratamento de perturbações melhoradas pela ativação dos recetores muscarínicos |
| US20240024261A1 (en) * | 2020-09-21 | 2024-01-25 | Dr. Raymond Lab Inc | Pharmaceutical composition for improving cognitive ability or enhancing memory |
| CA3199724A1 (en) * | 2020-11-26 | 2022-06-02 | Yusheng Xiong | Anticholinergic agents |
| US12109202B2 (en) | 2021-01-29 | 2024-10-08 | Qaam Pharmaceuticals, Llc | Fixed dose combination of cholinesterase inhibitor and a quaternary ammonium antimuscarinic agent to treat neurodegenerative cognitive disorders |
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| GB795758A (en) | 1955-08-22 | 1958-05-28 | Pfizer & Co C | Amino esters and the preparation thereof |
| US3480626A (en) | 1967-05-18 | 1969-11-25 | Chem Fab Dr R Pfleger | Certain azoniaspironortropine derivatives |
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| US4937239A (en) | 1989-02-13 | 1990-06-26 | Warner-Lambert Company | Azabicycloalkane oxime & azabicycloalkene oxime muscarinic agents |
| US5852029A (en) | 1990-04-10 | 1998-12-22 | Israel Institute For Biological Research | Aza spiro compounds acting on the cholinergic system with muscarinic agonist activity |
| NO2005012I1 (no) | 1994-12-28 | 2005-06-06 | Debio Rech Pharma Sa | Triptorelin og farmasoytisk akseptable salter derav |
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| EP0976404A3 (en) * | 1998-07-30 | 2001-06-27 | Pfizer Products Inc. | A pharmaceutical composition for the prevention and treatment of diseases of cognitive dysfunction in a mammal |
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| CA2436083A1 (en) * | 2001-02-08 | 2002-09-19 | Schering Corporation | Use of dual h3/m2 antagonists in the treatment of cognition deficit disorders |
| US8216609B2 (en) * | 2002-08-05 | 2012-07-10 | Torrent Pharmaceuticals Limited | Modified release composition of highly soluble drugs |
| US7427280B2 (en) * | 2002-09-06 | 2008-09-23 | Medtronic, Inc. | Method, system and device for treating disorders of the pelvic floor by delivering drugs to various nerves or tissues |
| US6974820B2 (en) | 2002-11-06 | 2005-12-13 | Bridge Pharma, Inc. | Methods for treating urinary incontinence and other disorders using trospium |
| CN1520818A (zh) | 2003-02-09 | 2004-08-18 | ɽ����Ҷ��Ȼҩ���о���������˾ | 治疗老年性痴呆的胆碱酯酶抑制剂药物组合物 |
| US8299062B2 (en) | 2003-09-17 | 2012-10-30 | Franklin Volvovitz | Pharmaceutical compositions and methods for preventing, treating, or reversing neuronal dysfunction |
| GB0322140D0 (en) * | 2003-09-22 | 2003-10-22 | Pfizer Ltd | Combinations |
| JP2007517905A (ja) | 2004-01-16 | 2007-07-05 | ワイス | アゾールを含有するベータアミロイド産生のヘテロ環式スルホンアミド阻害剤 |
| KR20060124712A (ko) | 2004-02-20 | 2006-12-05 | 노파르티스 아게 | 신경퇴행 및 인지 장애를 치료하기 위한 ｄｐｐ ⅳ 억제제 |
| AR051950A1 (es) | 2004-11-10 | 2007-02-21 | Osmotica Pharmaceutical Argent | Comprimido multicapa con capas que se separan |
| CA2592605C (en) | 2004-12-27 | 2010-12-07 | Eisai R&D Management Co., Ltd. | Method for stabilizing anti-dementia drug |
| US7390816B2 (en) | 2005-06-21 | 2008-06-24 | Bridge Pharma, Inc. | Methods for treating urinary incontinence in patients suffering from memory disorders |
| US20070004766A1 (en) | 2005-07-01 | 2007-01-04 | Aberg A K G | Methods for relaxation of smooth muscle contractions using Trospium |
| US20070224259A1 (en) | 2005-09-21 | 2007-09-27 | Gupta Anil K | Anti-inflammatory pharmaceutical composition |
| ATE544444T1 (de) | 2005-10-11 | 2012-02-15 | Yissum Res Dev Co | Zusammensetzungen für die nasale abgabe |
| CN101472877A (zh) * | 2006-04-21 | 2009-07-01 | 惠氏公司 | 制备手性纯氨基醇中间体、其衍生物及其用途 |
| WO2008033299A2 (en) * | 2006-09-12 | 2008-03-20 | Adolor Corporation | Use of n-containing spirocompounds for the enhancement of cognitive function |
| US20080090808A1 (en) | 2006-10-17 | 2008-04-17 | Franklin Volvovitz | Pharmaceutical compositions and methods for preventing, treating, or reversing neuronal dysfunction |
| US8097633B2 (en) * | 2006-11-15 | 2012-01-17 | Rich Steven A | Uses for quaternary ammonium anticholinergic muscarinic receptor antagonists in patients being treated for cognitive impairment or acute delirium |
| EP4088717A1 (en) * | 2008-03-27 | 2022-11-16 | Chase Pharmaceuticals Corporation | Use and composition for treating dementia |
| EP2478099B1 (en) * | 2009-09-18 | 2019-06-05 | Chase Pharmaceuticals Corporation | Combination for treating alzheimer-type dementia |
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| EP2271218A4 (en) | 2011-05-18 |
| US9044472B2 (en) | 2015-06-02 |
| EP2271218A1 (en) | 2011-01-12 |
| EP4088717A1 (en) | 2022-11-16 |
| CA2718411A1 (en) | 2009-10-01 |
| JP2014114295A (ja) | 2014-06-26 |
| US20150224096A1 (en) | 2015-08-13 |
| US20190091214A1 (en) | 2019-03-28 |
| JP2011518776A (ja) | 2011-06-30 |
| US20140275036A1 (en) | 2014-09-18 |
| MX2010010460A (es) | 2010-12-15 |
| US20130158012A1 (en) | 2013-06-20 |
| CA2718411C (en) | 2016-02-16 |
| JP5647099B2 (ja) | 2014-12-24 |
| MX347901B (es) | 2017-05-18 |
| EP3178477A1 (en) | 2017-06-14 |
| ES2634421T3 (es) | 2017-09-27 |
| US8404701B2 (en) | 2013-03-26 |
| EP2271218B1 (en) | 2017-05-24 |
| WO2009120277A1 (en) | 2009-10-01 |
| US20110021503A1 (en) | 2011-01-27 |
| JP6427522B2 (ja) | 2018-11-21 |
| AU2009229372C1 (en) | 2017-02-02 |
| AU2009229372B2 (en) | 2014-09-25 |
| AU2009229372A1 (en) | 2009-10-01 |
| MX344177B (es) | 2016-12-08 |
| JP2016179980A (ja) | 2016-10-13 |
| PL2271218T3 (pl) | 2017-10-31 |
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