DK2215226T3 - IMPROVING THE IMMOBILIZED MICROBIAL Nitrilase MAKING glycolic - Google Patents

IMPROVING THE IMMOBILIZED MICROBIAL Nitrilase MAKING glycolic Download PDF

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Publication number
DK2215226T3
DK2215226T3 DK08845012.7T DK08845012T DK2215226T3 DK 2215226 T3 DK2215226 T3 DK 2215226T3 DK 08845012 T DK08845012 T DK 08845012T DK 2215226 T3 DK2215226 T3 DK 2215226T3
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Denmark
Prior art keywords
nitrilase
glutaraldehyde
enzyme catalyst
catalyst
immobilized
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Application number
DK08845012.7T
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Danish (da)
English (en)
Inventor
Robert Dicosimo
Arie Ben-Bassat
Original Assignee
Du Pont
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Publication date
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Publication of DK2215226T3 publication Critical patent/DK2215226T3/en

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/78Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/06Enzymes or microbial cells immobilised on or in an organic carrier attached to the carrier via a bridging agent
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/10Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a carbohydrate
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/40Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42Hydroxy-carboxylic acids
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK08845012.7T 2007-10-31 2008-10-31 IMPROVING THE IMMOBILIZED MICROBIAL Nitrilase MAKING glycolic DK2215226T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/930,744 US7741088B2 (en) 2007-10-31 2007-10-31 Immobilized microbial nitrilase for production of glycolic acid
PCT/US2008/081952 WO2009059104A1 (en) 2007-10-31 2008-10-31 Improvement in immobilized microbial nitrilase for production of glycolic acid

Publications (1)

Publication Number Publication Date
DK2215226T3 true DK2215226T3 (en) 2016-03-07

Family

ID=40229742

Family Applications (1)

Application Number Title Priority Date Filing Date
DK08845012.7T DK2215226T3 (en) 2007-10-31 2008-10-31 IMPROVING THE IMMOBILIZED MICROBIAL Nitrilase MAKING glycolic

Country Status (8)

Country Link
US (2) US7741088B2 (https=)
EP (1) EP2215226B9 (https=)
JP (1) JP5583586B2 (https=)
CN (1) CN102016018B (https=)
DK (1) DK2215226T3 (https=)
ES (1) ES2562791T3 (https=)
PL (1) PL2215226T3 (https=)
WO (1) WO2009059104A1 (https=)

Families Citing this family (10)

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EP2480661A1 (en) * 2009-09-24 2012-08-01 UCB Pharma, S.A. Bacterial host strain
WO2011129820A1 (en) * 2010-04-14 2011-10-20 Strategic Enzyme Applications, Inc. Process for producing phosphinothricin employing nitrilases
CA2803959C (en) 2010-06-30 2021-01-19 Codexis, Inc. Chemically modified carbonic anhydrases useful in carbon capture systems
EP2627666B1 (de) * 2010-10-12 2015-07-08 c-LEcta GmbH Nitrilasen mit gesteigerte aktivität
EP3354742A1 (en) 2017-01-26 2018-08-01 Metabolic Explorer Methods and microorganisms for the production of glycolic acid and/or glyoxylic acid
CN108486088B (zh) 2018-02-14 2021-02-02 浙江工业大学 腈水解酶突变体及其应用
CA3116477A1 (en) * 2018-10-18 2020-04-23 Basf Se Method for the production of acrylic acid or salts thereof
CN112063607B (zh) * 2020-10-09 2021-12-07 浙江工业大学 一种腈水解酶突变体及其在催化合成2-氯烟酸中的应用
JP2023135741A (ja) * 2022-03-16 2023-09-29 三菱ケミカル株式会社 アミノ酸の製造方法
CN119570649A (zh) * 2024-07-12 2025-03-07 北京衍微科技有限公司 含红球菌发酵液的复合催化剂及其用途

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US2890238A (en) 1957-01-31 1959-06-09 Dow Chemical Co Preparation of glyconitrile
FR2245585B1 (https=) 1973-09-19 1976-05-14 Anvar
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US5187301A (en) 1989-10-26 1993-02-16 W. R. Grace & Co.-Conn. Preparation of iminodiacetonitrile from glycolonitrile
DE69131217T2 (de) 1990-03-30 1999-09-23 Mitsubishi Rayon Co., Ltd. Verfahren zur Herstellung von R(-)Mandelsäure und deren Derivaten
JP2974737B2 (ja) 1990-08-16 1999-11-10 三菱レイヨン株式会社 光学活性乳酸の製造法
EP0486289B1 (en) 1990-11-14 1997-07-09 Nitto Chemical Industry Co., Ltd. Biological process for producing alpha-hydroxyamide or alpha-hydroxy acid
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Also Published As

Publication number Publication date
EP2215226B9 (en) 2016-03-02
EP2215226B1 (en) 2015-12-02
EP2215226A1 (en) 2010-08-11
CN102016018B (zh) 2013-09-25
US7741088B2 (en) 2010-06-22
US20090111148A1 (en) 2009-04-30
US20100136656A1 (en) 2010-06-03
ES2562791T3 (es) 2016-03-08
JP2011501970A (ja) 2011-01-20
WO2009059104A1 (en) 2009-05-07
JP5583586B2 (ja) 2014-09-03
ES2562791T9 (es) 2016-04-18
PL2215226T3 (pl) 2016-06-30
US7867748B2 (en) 2011-01-11
CN102016018A (zh) 2011-04-13

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