DK209985A - Lipofile muramylpeptidderivater og midler indeholdende disse, samt fremgangsmaade til fremstilling af derivaterne - Google Patents
Lipofile muramylpeptidderivater og midler indeholdende disse, samt fremgangsmaade til fremstilling af derivaterne Download PDFInfo
- Publication number
- DK209985A DK209985A DK209985A DK209985A DK209985A DK 209985 A DK209985 A DK 209985A DK 209985 A DK209985 A DK 209985A DK 209985 A DK209985 A DK 209985A DK 209985 A DK209985 A DK 209985A
- Authority
- DK
- Denmark
- Prior art keywords
- group
- groups
- carbon atoms
- different
- lipophile
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
- C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
- C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
- C07K9/005—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure containing within the molecule the substructure with m, n > 0 and m+n > 0, A, B, D, E being heteroatoms; X being a bond or a chain, e.g. muramylpeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- Dispersion Chemistry (AREA)
- Nanotechnology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medical Informatics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8407340 | 1984-05-11 | ||
FR8407340A FR2564096B1 (fr) | 1984-05-11 | 1984-05-11 | Derives lipophiles de muramylpeptides ayant des proprietes d'activation des macrophages, compositions les contenant et procede pour les obtenir |
Publications (4)
Publication Number | Publication Date |
---|---|
DK209985D0 DK209985D0 (da) | 1985-05-10 |
DK209985A true DK209985A (da) | 1985-11-12 |
DK164918B DK164918B (da) | 1992-09-07 |
DK164918C DK164918C (da) | 1993-01-25 |
Family
ID=9303899
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK209985A DK164918C (da) | 1984-05-11 | 1985-05-10 | Lipofile muramylpeptidderivater med egenskaber til aktivering af makrofager og midler indeholdende disse muramylpeptidderivater |
Country Status (8)
Country | Link |
---|---|
US (2) | US4939122A (da) |
EP (1) | EP0165123B1 (da) |
JP (1) | JPH0670080B2 (da) |
AT (1) | ATE55394T1 (da) |
CA (1) | CA1259750A (da) |
DE (1) | DE3579051D1 (da) |
DK (1) | DK164918C (da) |
FR (1) | FR2564096B1 (da) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0256989A1 (en) * | 1986-08-18 | 1988-02-24 | Board Of Regents, The University Of Texas System | Pharmaceutical administration systems containing chemotactic peptides |
FR2609393A1 (fr) * | 1988-02-23 | 1988-07-15 | Serobiologiques Lab Sa | Composition notamment utile comme matiere de base pour la preparation de compositions pharmaceutiques, notamment dermatologiques et/ou cosmetiques comprenant une substance azotee, notamment aminoacides, oligo- ou polypeptides, proteines, et leurs derives, et composition pharmaceutique ou cosmetique ainsi preparee. |
CA2017507C (en) * | 1989-05-25 | 1996-11-12 | Gary Van Nest | Adjuvant formulation comprising a submicron oil droplet emulsion |
HU205147B (en) * | 1989-06-29 | 1992-03-30 | Sandoz Ag | Process for producing muramyl dipeptide derivative and pharmaceutical compostions comprising same |
FR2672496B3 (fr) * | 1990-07-18 | 1993-05-28 | Vacsyn France Sa | Compositions a base de substances hydrophobes, solubilisables dans un solvant aqueux, leur procede d'obtention, et leurs utilisations notamment dans le domaine pharmaceutique. |
FR2664813B1 (fr) * | 1990-07-18 | 1995-01-13 | Vacsyn France Sa | Compositions a base de substances hydrophobes, solubilisables dans un solvant aqueux, leur procede d'obtention, et leurs utilisations notamment dans le domaine pharmaceutique. |
FR2692149B1 (fr) * | 1992-06-12 | 1995-06-09 | Vacsyn France Sa | Composition adjuvante de l'immunite humorale et a mediation cellulaire n'induisant pas de reponse vis-a-vis de determinants auto-antigeniques. |
US5462735A (en) * | 1993-06-10 | 1995-10-31 | The United States Of America As Represented By The Secretary Of Agriculture | Pasteurella haemolytica subunit vaccine containing capsular polysaccharide and muramyl dipeptide |
AU3006697A (en) * | 1996-05-10 | 1997-12-05 | Endorex Corporation | Lipophile derivatives of muramylpeptides for treatment of retroviral infection and induction of chemokines |
EP1909758A1 (en) * | 2005-08-02 | 2008-04-16 | I.D.M. Immuno-Designed Molecules | Process for the preparation of liposomal formulations |
WO2016153938A1 (en) * | 2015-03-25 | 2016-09-29 | Biosynthetic Technologies, Llc | Ester compounds including triesters having terminal vicinal acyl groups |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2343035C2 (de) * | 1973-08-25 | 1982-04-01 | Hoechst Ag, 6000 Frankfurt | Pyroglutamyl-histidyl-prolinamide, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel |
GB1563561A (en) * | 1976-06-23 | 1980-03-26 | Daiichi Seiyaku Co | Muramyldipeptide derivatives and process for the preparation thereof |
JPS55111499A (en) * | 1979-02-21 | 1980-08-28 | Takeda Chem Ind Ltd | Glucosamine derivative and its preparation |
FI75578C (fi) * | 1979-07-25 | 1988-07-11 | Ciba Geigy Ag | Analogifoerfarande foer framstaellning av farmakologiskt verkande lipofila fosfatidylmuramylpeptider. |
US4406889A (en) * | 1980-02-15 | 1983-09-27 | Ciba-Geigy Corporation | Derivatives of aldohexoses, intermediates, processes for their manufacture, preparations containing such compounds, and their use |
US4310514A (en) * | 1980-05-05 | 1982-01-12 | Merck & Co., Inc. | Immunologically active dipeptidyl 5-0,6-0-acyl-2-amino-2-deoxy-D-glucofuranose derivatives and methods of preparation |
US4315913A (en) * | 1980-06-09 | 1982-02-16 | Merck & Co. Inc. | Immunologically active dipeptidyl 2-amino-1,2-dideoxy-D-glucose derivatives and methods of preparation |
GR78246B (da) * | 1981-01-23 | 1984-09-26 | Ciba Geigy Ag | |
EP0102319B1 (de) * | 1982-07-23 | 1987-08-19 | Ciba-Geigy Ag | Verwendung von Muramylpeptiden oder deren Analogen zur Prophylaxe und Therapie von Virusinfektionen |
US4683292A (en) * | 1983-08-12 | 1987-07-28 | Immunetech, Inc. | Immunotherapeutic polypeptide agents which bind to lymphocyte immunoglobulin FC receptors |
US4579840A (en) * | 1983-08-12 | 1986-04-01 | Immunetech Pharmaceuticals | Method of blocking immune complex binding to immunoglobulin Fc receptors |
JPS6042398A (ja) * | 1983-08-18 | 1985-03-06 | Toshiyuki Hamaoka | ムラミルジペプチド活性エステル誘導体 |
ZA846192B (en) * | 1984-08-09 | 1986-03-26 | Merck Patent Gmbh | Immunotherapeutic polypeptide agents |
JPS6157597A (ja) * | 1984-08-29 | 1986-03-24 | Toshiyuki Hamaoka | ムラミルペプチド活性エステル誘導体 |
-
1984
- 1984-05-11 FR FR8407340A patent/FR2564096B1/fr not_active Expired
-
1985
- 1985-05-10 EP EP85400921A patent/EP0165123B1/fr not_active Expired - Lifetime
- 1985-05-10 DK DK209985A patent/DK164918C/da not_active IP Right Cessation
- 1985-05-10 DE DE8585400921T patent/DE3579051D1/de not_active Expired - Fee Related
- 1985-05-10 JP JP60099454A patent/JPH0670080B2/ja not_active Expired - Lifetime
- 1985-05-10 AT AT85400921T patent/ATE55394T1/de not_active IP Right Cessation
- 1985-05-13 CA CA000481425A patent/CA1259750A/fr not_active Expired
-
1988
- 1988-06-09 US US07/206,959 patent/US4939122A/en not_active Ceased
-
1994
- 1994-10-25 US US08/329,142 patent/USRE35706E/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
ATE55394T1 (de) | 1990-08-15 |
DE3579051D1 (de) | 1990-09-13 |
JPH0670080B2 (ja) | 1994-09-07 |
EP0165123A2 (fr) | 1985-12-18 |
US4939122A (en) | 1990-07-03 |
DK164918B (da) | 1992-09-07 |
EP0165123A3 (en) | 1986-03-05 |
EP0165123B1 (fr) | 1990-08-08 |
DK164918C (da) | 1993-01-25 |
DK209985D0 (da) | 1985-05-10 |
JPS60252497A (ja) | 1985-12-13 |
FR2564096B1 (fr) | 1988-02-19 |
CA1259750A (fr) | 1989-09-19 |
FR2564096A1 (fr) | 1985-11-15 |
USRE35706E (en) | 1997-12-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PBP | Patent lapsed |