DK201070087A - Hidtil ukendt fiskelusvaccine - Google Patents
Hidtil ukendt fiskelusvaccine Download PDFInfo
- Publication number
- DK201070087A DK201070087A DKPA201070087A DKPA201070087A DK201070087A DK 201070087 A DK201070087 A DK 201070087A DK PA201070087 A DKPA201070087 A DK PA201070087A DK PA201070087 A DKPA201070087 A DK PA201070087A DK 201070087 A DK201070087 A DK 201070087A
- Authority
- DK
- Denmark
- Prior art keywords
- protein
- acid sequence
- nucleic acid
- immunogenic fragment
- vaccine
- Prior art date
Links
- 229960005486 vaccine Drugs 0.000 title claims 7
- 241000239267 Arguloida Species 0.000 title claims 4
- 102000004169 proteins and genes Human genes 0.000 claims 29
- 108090000623 proteins and genes Proteins 0.000 claims 29
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 12
- 150000007523 nucleic acids Chemical group 0.000 claims 12
- 239000012634 fragment Substances 0.000 claims 11
- 230000002163 immunogen Effects 0.000 claims 11
- 125000003275 alpha amino acid group Chemical group 0.000 claims 6
- 102000053602 DNA Human genes 0.000 claims 4
- 108020004511 Recombinant DNA Proteins 0.000 claims 4
- 239000000427 antigen Substances 0.000 claims 3
- 102000036639 antigens Human genes 0.000 claims 3
- 108091007433 antigens Proteins 0.000 claims 3
- 239000003937 drug carrier Substances 0.000 claims 3
- 208000015181 infectious disease Diseases 0.000 claims 3
- 241000700605 Viruses Species 0.000 claims 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
- 241000251468 Actinopterygii Species 0.000 claims 1
- 239000002671 adjuvant Substances 0.000 claims 1
- 230000002068 genetic effect Effects 0.000 claims 1
- 244000000010 microbial pathogen Species 0.000 claims 1
- 244000005700 microbiome Species 0.000 claims 1
- 244000052769 pathogen Species 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
- C07K14/43509—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from crustaceans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/14—Ectoparasiticides, e.g. scabicides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Insects & Arthropods (AREA)
- General Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Claims (14)
1. Protein på 200 kD eller et immunogent fragment af proteinet, idet proteinet eller det immunogene fragment deraf har en aminosyresekvens, der er mindst 70% identisk med aminosyresekvensen som afbildet i SEQ ID NO: 2.
2. Protein på 180 kD eller et immunogent fragment af proteinet, idet proteinet eller det immunogene fragment deraf har en aminosyresekvens, der er mindst 70% identisk med aminosyresekvensen som afbildet i SEQ ID NO: 4.
3. Protein på 100/85 kD eller et immunogent fragment af proteinet, idet proteinet eller det immunogene fragment deraf har en aminosyresekvens, der er mindst 70% identisk med aminosyresekvensen som afbildet i SEQ ID NO: 6.
4. Vaccine til bekæmpelse af fiskelusinfektion, kendetegnet ved, at den omfatter et protein på 200 kD ifølge krav 1, et protein på 180 kD ifølge krav 2 eller et protein på 100/85 kD ifølge krav 3, eller et immunogent fragment af et hvilket som helst af proteinerne, samt en farmaceutisk acceptabel bærer.
5. Vaccine til bekæmpelse af fiskelusinfektion, kendetegnet ved, at den omfatter antistoffer mod et protein på 200 kD ifølge krav 1, et protein på 180 kD ifølge krav 2 eller et protein på 100/85 kD ifølge krav 3, eller et immunogent fragment af et hvilket som helst af proteinerne, samt en farmaceutisk acceptabel bærer.
6. Vaccine ifølge krav 4 eller 5, kendetegnet ved, at den omfatter en adju-vans.
7. Nucleinsyresekvens, som koder for et protein på 200 kD eller for et immunogent fragment af proteinet, idet nucleinsyresekvensen har mindst 70% identitet med nucleinsyresekvensen som afbildet i SEQ ID NO: 1.
8. Nucleinsyresekvens, som koder for et protein på 180 kD eller for et immu-nogent fragment af proteinet, idet nucleinsyresekvensen har mindst 70% identitet med nucleinsyresekvensen som afbildet i SEQ ID NO: 3.
9. Nucleinsyresekvens, som koder for et protein på 100/85 kD eller for et im-munogent fragment af proteinet, idet nucleinsyresekvensen har mindst 70% identitet med nucleinsyresekvensen som afbildet i SEQ ID NO: 5.
10. Rekombinant DNA-molekyle, der omfatter en nucleinsyresekvens som beskrevet i et hvilket som helst af kravene 7 - 9, og som er under styring af en funktionelt linket promotor.
11. Levende, rekombinant bærer, som er mikroorganismer eller vira og som omfatter et rekombinant DNA-molekyle ifølge krav 10.
12. Vaccine til bekæmpelse af fiskelusinfektion, kendetegnet ved, at den omfatter en nucleinsyresekvens som beskrevet i et hvilket som helst af kravene 7 -9, et rekombinant DNA-molekyle ifølge krav 10 eller en levende, rekombinant bærer ifølge krav 11, samt en farmaceutisk acceptabel bærer.
13. Vaccine ifølge et hvilket som helst af kravene 4-6 eller 12, kendetegnet ved, at den omfatter et yderligere, af et virus afledt antigen, en over for fisk patogen organisme eller mikroorganisme, et antistof mod antigenet, eller genetisk information, som koder for antigenet.
14. Fremgangsmåde til fremstilling af en vaccine ifølge et hvilket som helst af kravene 4-6 eller 12, idet fremgangsmåden omfatter blanding af et protein på 200 kD ifølge krav eller antistoffer mod proteinet på 200 kD, et protein på 180 kD ifølge krav 2 eller antistoffer mod proteinet på 180 kD, et protein på 100/85 kD ifølge krav 3 eller antistoffer mod proteinet på 100/85 kD, en nucleinsyresekvens ifølge et hvilket som helst af kravene 7 - 9, et rekombinant DNA-molekyle ifølge krav 10 eller en levende, rekombinant bærer ifølge krav 11, samt en farmaceutisk acceptabel bærer.
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05109261 | 2005-10-05 | ||
| EP05109260 | 2005-10-05 | ||
| EP05109258 | 2005-10-05 | ||
| EP05109259 | 2005-10-05 | ||
| DK200800635A DK200800635A (da) | 2005-10-05 | 2008-05-05 | Hidtil ukendt fiskelusvaccine. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK201070087A true DK201070087A (da) | 2010-03-05 |
Family
ID=37696028
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK200800635A DK200800635A (da) | 2005-10-05 | 2008-05-05 | Hidtil ukendt fiskelusvaccine. |
| DKPA201070087A DK201070087A (da) | 2005-10-05 | 2010-03-05 | Hidtil ukendt fiskelusvaccine |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK200800635A DK200800635A (da) | 2005-10-05 | 2008-05-05 | Hidtil ukendt fiskelusvaccine. |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP1934247A1 (da) |
| JP (1) | JP2009511005A (da) |
| CA (1) | CA2624486A1 (da) |
| DK (2) | DK200800635A (da) |
| NO (1) | NO20081541L (da) |
| TW (1) | TW200801034A (da) |
| WO (1) | WO2007039599A1 (da) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1789554B1 (en) * | 2004-07-28 | 2018-07-04 | National Research Council Of Canada | Recombinant vaccines against caligid copepods (sea lice) and antigen sequences thereof |
| CU23634A1 (es) * | 2007-05-31 | 2011-02-24 | Ct Ingenieria Genetica Biotech | Secuencias de ácido nucleico y aminoácidos, y vacuna para el control de infestaciones por ectoparásitos en peces |
| EP2211900A1 (en) | 2007-11-19 | 2010-08-04 | Calanus AS | Bioactive copepod-compositions, processes for the production thereof, and use thereof to prevent or treat hosts infested by phylogenetically similar ectoparasites |
| GB201902425D0 (en) * | 2019-02-22 | 2019-04-10 | Benchmark Animal Health Ltd | Sea lice antigens and vaccines |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1789554B1 (en) * | 2004-07-28 | 2018-07-04 | National Research Council Of Canada | Recombinant vaccines against caligid copepods (sea lice) and antigen sequences thereof |
-
2006
- 2006-09-27 TW TW095135847A patent/TW200801034A/zh unknown
- 2006-10-03 WO PCT/EP2006/066978 patent/WO2007039599A1/en active Application Filing
- 2006-10-03 JP JP2008533995A patent/JP2009511005A/ja active Pending
- 2006-10-03 CA CA002624486A patent/CA2624486A1/en not_active Abandoned
- 2006-10-03 EP EP06806932A patent/EP1934247A1/en not_active Withdrawn
-
2008
- 2008-03-31 NO NO20081541A patent/NO20081541L/no not_active Application Discontinuation
- 2008-05-05 DK DK200800635A patent/DK200800635A/da not_active Application Discontinuation
-
2010
- 2010-03-05 DK DKPA201070087A patent/DK201070087A/da not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1934247A1 (en) | 2008-06-25 |
| CA2624486A1 (en) | 2007-04-12 |
| TW200801034A (en) | 2008-01-01 |
| WO2007039599A1 (en) | 2007-04-12 |
| NO20081541L (no) | 2008-07-02 |
| JP2009511005A (ja) | 2009-03-19 |
| DK200800635A (da) | 2008-05-05 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HRP20191594T1 (hr) | Poticanje imunosnog odgovora | |
| CN106232813B (zh) | 预防减蛋综合征(eds)的疫苗 | |
| NZ627888A (en) | Materials and methods for respiratory disease control in canines | |
| RU2677799C2 (ru) | Модифицированные суперспиральные белки с улучшенными свойствами | |
| US7951376B2 (en) | Multimeric complexes of antigens and an adjuvant | |
| AR047347A1 (es) | Miembros de la familia cry9 de bacillus | |
| CN104780937A (zh) | 涉及由多核苷酸编码的免疫原性多肽的新型初免-加强方案 | |
| DK201070087A (da) | Hidtil ukendt fiskelusvaccine | |
| WO2022071513A1 (ja) | ＳＡＲＳ－ＣｏＶ－２に対する改良型ＤＮＡワクチン | |
| CN103483449A (zh) | 两种scFv抗体、其编码基因及其在制备治疗或预防鸡传染性法氏囊病制剂中的应用 | |
| AU2018351209B2 (en) | Mutant of H3N2 subtype influenza virus hemagglutinin protein and use thereof | |
| CN104755619B (zh) | 用于预防猪水肿病的疫苗 | |
| CN105408347A (zh) | 寡聚流感免疫原性组合物 | |
| CN105384815B (zh) | 一种scFv抗体在治疗或预防鸡传染性法氏囊病制剂中的应用 | |
| CN1289682C (zh) | 通过使用牛痘ati启动子表达改良的安卡拉痘苗病毒中的基因 | |
| RU2012149036A (ru) | Векторы парапоксвируса, содержащие антиген вируса бешенства | |
| Feng et al. | Chichen type III interferon produced by silkworm bioreactor induces ISG expression and restricts ALV-J infection in vitro | |
| CN114409803B (zh) | 流感病毒三聚体亚单位疫苗及其应用 | |
| CN115975053A (zh) | 靶向新型冠状病毒的疫苗 | |
| JP6373601B2 (ja) | アカバネウイルスに対して中和活性を有する抗体を誘導するペプチド | |
| CN108484759A (zh) | 两种scFv抗体、其编码基因及其在制备治疗或预防鸡传染性法氏囊病制剂中的应用 | |
| BR9508645B1 (pt) | seqÜÊncia de nucleotÍdeos isolada compreendendo o gene s fipv tendo uma seqÜencia de nucleotÍdeos da cepa 79-1146 fipv, bem como polipeptÍdeo, vacina e composiÇço compreendendo a mesma. | |
| TW202031893A (zh) | Vlp表現cho細胞株之建構 | |
| CA2494197A1 (en) | Streptococcus uberis protein, nucleic acid sequence encoding the same and its use in a mastitis vaccine | |
| WO2023217286A1 (zh) | 融合蛋白以及其应用 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHS | Application shelved for other reasons than non-payment |