DK201070087A - Hitherto unknown fish lice vaccine - Google Patents

Hitherto unknown fish lice vaccine Download PDF

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Publication number
DK201070087A
DK201070087A DKPA201070087A DKPA201070087A DK201070087A DK 201070087 A DK201070087 A DK 201070087A DK PA201070087 A DKPA201070087 A DK PA201070087A DK PA201070087 A DKPA201070087 A DK PA201070087A DK 201070087 A DK201070087 A DK 201070087A
Authority
DK
Denmark
Prior art keywords
protein
acid sequence
nucleic acid
immunogenic fragment
vaccine
Prior art date
Application number
DKPA201070087A
Other languages
Danish (da)
Inventor
Frost Petter
Nilsen Frank
Hamre Lars Are
Original Assignee
Intervet Int Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intervet Int Bv filed Critical Intervet Int Bv
Publication of DK201070087A publication Critical patent/DK201070087A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43509—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from crustaceans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/14—Ectoparasiticides, e.g. scabicides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Claims (14)

1. Protein på 200 kD eller et immunogent fragment af proteinet, idet proteinet eller det immunogene fragment deraf har en aminosyresekvens, der er mindst 70% identisk med aminosyresekvensen som afbildet i SEQ ID NO: 2.A 200 kD protein or an immunogenic fragment of the protein, the protein or immunogenic fragment thereof having an amino acid sequence at least 70% identical to the amino acid sequence depicted in SEQ ID NO: 2. 2. Protein på 180 kD eller et immunogent fragment af proteinet, idet proteinet eller det immunogene fragment deraf har en aminosyresekvens, der er mindst 70% identisk med aminosyresekvensen som afbildet i SEQ ID NO: 4.A 180 kD protein or an immunogenic fragment of the protein, the protein or its immunogenic fragment having an amino acid sequence at least 70% identical to the amino acid sequence depicted in SEQ ID NO: 4. 3. Protein på 100/85 kD eller et immunogent fragment af proteinet, idet proteinet eller det immunogene fragment deraf har en aminosyresekvens, der er mindst 70% identisk med aminosyresekvensen som afbildet i SEQ ID NO: 6.3. A 100/85 kD protein or an immunogenic fragment of the protein, the protein or immunogenic fragment thereof having an amino acid sequence at least 70% identical to the amino acid sequence depicted in SEQ ID NO: 6. 4. Vaccine til bekæmpelse af fiskelusinfektion, kendetegnet ved, at den omfatter et protein på 200 kD ifølge krav 1, et protein på 180 kD ifølge krav 2 eller et protein på 100/85 kD ifølge krav 3, eller et immunogent fragment af et hvilket som helst af proteinerne, samt en farmaceutisk acceptabel bærer.Vaccine for controlling fish lice infection, characterized in that it comprises a 200 kD protein according to claim 1, a 180 kD protein according to claim 2 or a 100/85 kD protein according to claim 3, or an immunogenic fragment of any any of the proteins, as well as a pharmaceutically acceptable carrier. 5. Vaccine til bekæmpelse af fiskelusinfektion, kendetegnet ved, at den omfatter antistoffer mod et protein på 200 kD ifølge krav 1, et protein på 180 kD ifølge krav 2 eller et protein på 100/85 kD ifølge krav 3, eller et immunogent fragment af et hvilket som helst af proteinerne, samt en farmaceutisk acceptabel bærer.Vaccine for controlling fish lice infection, characterized in that it comprises antibodies against a 200 kD protein according to claim 1, a 180 kD protein according to claim 2 or a 100/85 kD protein according to claim 3, or an immunogenic fragment of any of the proteins, as well as a pharmaceutically acceptable carrier. 6. Vaccine ifølge krav 4 eller 5, kendetegnet ved, at den omfatter en adju-vans.Vaccine according to claim 4 or 5, characterized in that it comprises an adjuvant. 7. Nucleinsyresekvens, som koder for et protein på 200 kD eller for et immunogent fragment af proteinet, idet nucleinsyresekvensen har mindst 70% identitet med nucleinsyresekvensen som afbildet i SEQ ID NO: 1.A nucleic acid sequence encoding a 200 kD protein or an immunogenic fragment of the protein, the nucleic acid sequence having at least 70% identity to the nucleic acid sequence as depicted in SEQ ID NO: 1. 8. Nucleinsyresekvens, som koder for et protein på 180 kD eller for et immu-nogent fragment af proteinet, idet nucleinsyresekvensen har mindst 70% identitet med nucleinsyresekvensen som afbildet i SEQ ID NO: 3.A nucleic acid sequence encoding a 180 kD protein or an immunogenic fragment of the protein, the nucleic acid sequence having at least 70% identity to the nucleic acid sequence depicted in SEQ ID NO: 3. 9. Nucleinsyresekvens, som koder for et protein på 100/85 kD eller for et im-munogent fragment af proteinet, idet nucleinsyresekvensen har mindst 70% identitet med nucleinsyresekvensen som afbildet i SEQ ID NO: 5.A nucleic acid sequence encoding a 100/85 kD protein or an immunogenic fragment of the protein, the nucleic acid sequence having at least 70% identity to the nucleic acid sequence depicted in SEQ ID NO: 5. 10. Rekombinant DNA-molekyle, der omfatter en nucleinsyresekvens som beskrevet i et hvilket som helst af kravene 7 - 9, og som er under styring af en funktionelt linket promotor.A recombinant DNA molecule comprising a nucleic acid sequence as described in any one of claims 7 to 9 and which is under the control of a functionally linked promoter. 11. Levende, rekombinant bærer, som er mikroorganismer eller vira og som omfatter et rekombinant DNA-molekyle ifølge krav 10.A living, recombinant carrier which is microorganisms or viruses and comprises a recombinant DNA molecule according to claim 10. 12. Vaccine til bekæmpelse af fiskelusinfektion, kendetegnet ved, at den omfatter en nucleinsyresekvens som beskrevet i et hvilket som helst af kravene 7 -9, et rekombinant DNA-molekyle ifølge krav 10 eller en levende, rekombinant bærer ifølge krav 11, samt en farmaceutisk acceptabel bærer.Vaccine for controlling fish lice infection, characterized in that it comprises a nucleic acid sequence as described in any one of claims 7 to 9, a recombinant DNA molecule according to claim 10 or a live recombinant carrier according to claim 11, and a pharmaceutical acceptable carrier. 13. Vaccine ifølge et hvilket som helst af kravene 4-6 eller 12, kendetegnet ved, at den omfatter et yderligere, af et virus afledt antigen, en over for fisk patogen organisme eller mikroorganisme, et antistof mod antigenet, eller genetisk information, som koder for antigenet.Vaccine according to any one of claims 4 to 6 or 12, characterized in that it comprises an additional virus-derived antigen, a fish pathogenic organism or microorganism, an antibody to the antigen, or genetic information which codes for the antigen. 14. Fremgangsmåde til fremstilling af en vaccine ifølge et hvilket som helst af kravene 4-6 eller 12, idet fremgangsmåden omfatter blanding af et protein på 200 kD ifølge krav eller antistoffer mod proteinet på 200 kD, et protein på 180 kD ifølge krav 2 eller antistoffer mod proteinet på 180 kD, et protein på 100/85 kD ifølge krav 3 eller antistoffer mod proteinet på 100/85 kD, en nucleinsyresekvens ifølge et hvilket som helst af kravene 7 - 9, et rekombinant DNA-molekyle ifølge krav 10 eller en levende, rekombinant bærer ifølge krav 11, samt en farmaceutisk acceptabel bærer.A method of producing a vaccine according to any one of claims 4-6 or 12, the method comprising mixing a 200 kD protein according to claim or antibodies to the 200 kD protein, a 180 kD protein according to claim 2 or antibodies against the 180 kD protein, a 100/85 kD protein according to claim 3 or antibodies against the 100/85 kD protein, a nucleic acid sequence according to any one of claims 7 - 9, a recombinant DNA molecule according to claim 10 or a a living recombinant carrier according to claim 11, as well as a pharmaceutically acceptable carrier.
DKPA201070087A 2005-10-05 2010-03-05 Hitherto unknown fish lice vaccine DK201070087A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP05109260 2005-10-05
EP05109261 2005-10-05
EP05109259 2005-10-05
EP05109258 2005-10-05
DK200800635A DK200800635A (en) 2005-10-05 2008-05-05 Hitherto unknown fish lice vaccine.

Publications (1)

Publication Number Publication Date
DK201070087A true DK201070087A (en) 2010-03-05

Family

ID=37696028

Family Applications (2)

Application Number Title Priority Date Filing Date
DK200800635A DK200800635A (en) 2005-10-05 2008-05-05 Hitherto unknown fish lice vaccine.
DKPA201070087A DK201070087A (en) 2005-10-05 2010-03-05 Hitherto unknown fish lice vaccine

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK200800635A DK200800635A (en) 2005-10-05 2008-05-05 Hitherto unknown fish lice vaccine.

Country Status (7)

Country Link
EP (1) EP1934247A1 (en)
JP (1) JP2009511005A (en)
CA (1) CA2624486A1 (en)
DK (2) DK200800635A (en)
NO (1) NO20081541L (en)
TW (1) TW200801034A (en)
WO (1) WO2007039599A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2397553T3 (en) * 2004-07-28 2017-03-31 National Research Council Of Canada Recombinant vaccines against caligid copepods (sea lice) and antigen sequences thereof
CU23634A1 (en) * 2007-05-31 2011-02-24 Ct Ingenieria Genetica Biotech SEQUENCES OF NUCLEIC ACID AND AMINO ACIDS, AND VACCINE FOR THE CONTROL OF INFESTATIONS BY ECTOPARASITES IN FISH
WO2009067020A1 (en) 2007-11-19 2009-05-28 Calanus As Bioactive copepod-compositions, processes for the production thereof, and use thereof to prevent or treat hosts infested by phylogenetically similar ectoparasites
GB201902425D0 (en) * 2019-02-22 2019-04-10 Benchmark Animal Health Ltd Sea lice antigens and vaccines

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2397553T3 (en) * 2004-07-28 2017-03-31 National Research Council Of Canada Recombinant vaccines against caligid copepods (sea lice) and antigen sequences thereof

Also Published As

Publication number Publication date
CA2624486A1 (en) 2007-04-12
EP1934247A1 (en) 2008-06-25
TW200801034A (en) 2008-01-01
DK200800635A (en) 2008-05-05
WO2007039599A1 (en) 2007-04-12
NO20081541L (en) 2008-07-02
JP2009511005A (en) 2009-03-19

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