DK2010544T3 - Fremgangsmåde til fremstilling af Dorzolamid - Google Patents

Fremgangsmåde til fremstilling af Dorzolamid

Info

Publication number
DK2010544T3
DK2010544T3 DK07728156T DK07728156T DK2010544T3 DK 2010544 T3 DK2010544 T3 DK 2010544T3 DK 07728156 T DK07728156 T DK 07728156T DK 07728156 T DK07728156 T DK 07728156T DK 2010544 T3 DK2010544 T3 DK 2010544T3
Authority
DK
Denmark
Prior art keywords
dorzolamide
preparation
camphorsulfonic acid
camphorsulfonate
racemate
Prior art date
Application number
DK07728156T
Other languages
Danish (da)
English (en)
Inventor
Paolo Maragni
Ivan Michieletto
Livius Cotarca
Original Assignee
Zach System Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zach System Spa filed Critical Zach System Spa
Application granted granted Critical
Publication of DK2010544T3 publication Critical patent/DK2010544T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Catalysts (AREA)
  • Dental Preparations (AREA)
DK07728156T 2006-04-21 2007-04-16 Fremgangsmåde til fremstilling af Dorzolamid DK2010544T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06112883 2006-04-21
PCT/EP2007/053691 WO2007122130A1 (fr) 2006-04-21 2007-04-16 Procédé de synthèse de dorzolamide

Publications (1)

Publication Number Publication Date
DK2010544T3 true DK2010544T3 (da) 2009-11-30

Family

ID=38137401

Family Applications (1)

Application Number Title Priority Date Filing Date
DK07728156T DK2010544T3 (da) 2006-04-21 2007-04-16 Fremgangsmåde til fremstilling af Dorzolamid

Country Status (14)

Country Link
US (1) US8183391B2 (fr)
EP (1) EP2010544B1 (fr)
JP (1) JP5097770B2 (fr)
CN (1) CN101426795B (fr)
AT (1) ATE438649T1 (fr)
CA (1) CA2646133A1 (fr)
CY (1) CY1110510T1 (fr)
DE (1) DE602007001885D1 (fr)
DK (1) DK2010544T3 (fr)
ES (1) ES2331162T3 (fr)
HR (1) HRP20090578T1 (fr)
PT (1) PT2010544E (fr)
SI (1) SI2010544T1 (fr)
WO (1) WO2007122130A1 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20121165A1 (it) 2012-07-03 2014-01-04 Zach System Spa Processo di riduzione asimmetrica
CN103497202B (zh) * 2013-10-23 2015-12-02 武汉武药科技有限公司 盐酸多佐胺中间体的合成方法
US20160332962A1 (en) * 2015-05-13 2016-11-17 Janssen Pharmaceutica Nv (s)-csa salt of s-ketamine, (r)-csa salt of s-ketamine and processes for the preparation of s-ketamine
CN108822127B (zh) * 2018-05-30 2020-05-15 沈阳药科大学 4-羟亚胺基噻吩并[2,3-b]噻喃-2-甲酰胺类化合物及其用途
CN108586485B (zh) * 2018-05-30 2020-05-15 沈阳药科大学 1-(4-羟亚胺基噻吩并[2,3-b]噻喃甲酰基)哌嗪类化合物及其应用
CN108822126B (zh) * 2018-05-30 2020-05-15 沈阳药科大学 噻吩并噻喃甲酰基哌嗪类化合物及其医药用途
CN110903299A (zh) * 2018-09-17 2020-03-24 武汉武药科技有限公司 一种盐酸多佐胺的精制方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3810899A (en) * 1972-03-10 1974-05-14 Hoffmann La Roche 2-hydroxy-n-substituted-morphinan derivatives
DD150456A5 (de) * 1979-03-01 1981-09-02 Ciba Geigy Ag Verfahren zur herstellung von derivaten des 3-amino-1,2-propandiols
US4863922A (en) * 1984-12-12 1989-09-05 Merck & Co., Inc. Substituted aromatic sulfonamides as antiglaucoma agents, compositions and use
JP4218310B2 (ja) * 2002-11-06 2009-02-04 住友化学株式会社 光学活性２−アミノ−２−フェニルエタノール類の製造方法およびその中間体
US20050059696A1 (en) 2003-05-08 2005-03-17 Dr. Reddy's Laboratories Limited Process for the recovery of S -(+)-methyl- (2-chlorophenyl)- (6,7-dihydro- 4H-thieno [3,2-c] pyrid-5-yl) acetate hydrogen sulfate (clopidogrel bisulfate) from its (R) and mixture of (R) and (S)- isomers
CN1293041C (zh) * 2003-05-30 2007-01-03 上海实业化工有限公司 D－(－)－1－苯甘氨酸的制备方法
DE10336185A1 (de) 2003-08-07 2005-02-24 Bayer Chemicals Ag Enantiomerenangereicherte 1-Phenylethylamine
MXPA06015274A (es) * 2004-07-09 2007-09-27 Fdc Ltd Un procedimiento mejorado para la preparacion de 5,6-dihidro-4h-4(s)-etilamino-6(s)-metiltieno [2,3-b] tiopiran-2-sulfonamida-7,7-dioxido y sus sales.

Also Published As

Publication number Publication date
HRP20090578T1 (hr) 2009-11-30
CN101426795B (zh) 2011-01-12
ATE438649T1 (de) 2009-08-15
CN101426795A (zh) 2009-05-06
WO2007122130A1 (fr) 2007-11-01
ES2331162T3 (es) 2009-12-22
JP5097770B2 (ja) 2012-12-12
CA2646133A1 (fr) 2007-11-01
EP2010544A1 (fr) 2009-01-07
EP2010544B1 (fr) 2009-08-05
DE602007001885D1 (de) 2009-09-17
SI2010544T1 (sl) 2009-12-31
US8183391B2 (en) 2012-05-22
PT2010544E (pt) 2009-11-03
CY1110510T1 (el) 2015-04-29
US20090275759A1 (en) 2009-11-05
JP2009534349A (ja) 2009-09-24

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