DK199788A - Haemning af interleukin-1 produktion af monocytter og/eller makrofager - Google Patents

Haemning af interleukin-1 produktion af monocytter og/eller makrofager

Info

Publication number
DK199788A
DK199788A DK199788A DK199788A DK199788A DK 199788 A DK199788 A DK 199788A DK 199788 A DK199788 A DK 199788A DK 199788 A DK199788 A DK 199788A DK 199788 A DK199788 A DK 199788A
Authority
DK
Denmark
Prior art keywords
monocytes
macrophages
interleukin
inhibition
production
Prior art date
Application number
DK199788A
Other languages
Danish (da)
English (en)
Other versions
DK199788D0 (da
Inventor
Paul Elliot Bender
Don Edgar Griswold
Nabil Hanna
John C Lee
Original Assignee
Smithkline Beckman Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beckman Corp filed Critical Smithkline Beckman Corp
Publication of DK199788D0 publication Critical patent/DK199788D0/da
Publication of DK199788A publication Critical patent/DK199788A/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
DK199788A 1986-08-19 1988-04-12 Haemning af interleukin-1 produktion af monocytter og/eller makrofager DK199788A (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US89790986A 1986-08-19 1986-08-19
US07/063,550 US4794114A (en) 1986-08-19 1987-06-17 Inhibition of interleukin-1 production by monocytes and/or macrophages
PCT/US1987/002014 WO1988001169A1 (fr) 1986-08-19 1987-08-17 Inhibition de la production d'interleukine-1 par des monocytes et/ou des macrophages

Publications (2)

Publication Number Publication Date
DK199788D0 DK199788D0 (da) 1988-04-12
DK199788A true DK199788A (da) 1988-04-12

Family

ID=26743522

Family Applications (1)

Application Number Title Priority Date Filing Date
DK199788A DK199788A (da) 1986-08-19 1988-04-12 Haemning af interleukin-1 produktion af monocytter og/eller makrofager

Country Status (10)

Country Link
US (1) US4794114A (fr)
EP (1) EP0321490B1 (fr)
JP (1) JPH01503782A (fr)
AT (1) ATE107507T1 (fr)
AU (1) AU7880087A (fr)
CA (1) CA1292694C (fr)
DE (1) DE3750140D1 (fr)
DK (1) DK199788A (fr)
GR (1) GR871277B (fr)
WO (1) WO1988001169A1 (fr)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR920702621A (ko) * 1989-06-13 1992-10-06 스튜어트 알. 슈터 단핵세포 및/또는 마크로파지에 의한 인터루킨-1 또는 종양회사인자 생성의 억제
AU5921890A (en) * 1989-06-13 1991-01-08 Smithkline Beecham Corporation Monokine activity interference
US5714140A (en) * 1989-12-13 1998-02-03 Otsuka Pharmaceutical Co., Ltd. Method for inhibiting the production of bioactive IL-1 by administering M-CSF
EP0489690A1 (fr) * 1990-12-05 1992-06-10 Ciba-Geigy Ag N-Benzoyl-N'-(2-phényléthyl)-pipérazines substituées
GB9026926D0 (en) * 1990-12-12 1991-01-30 Smith Kline French Lab Novel process
US6228356B1 (en) 1990-12-20 2001-05-08 University Of Pittsburgh Of The Commonwealth System Of Higher Education Viral vectors to inhibit leukocyte infiltration or cartilage degradation of joints
US6413511B1 (en) 1990-12-20 2002-07-02 University Of Pittsburgh Of The Commonwealth System Of Higher Education Cartilage alterations by administering to joints chondrocytes comprising a heterologous polynucleotide
US5858355A (en) * 1990-12-20 1999-01-12 University Of Pittsburgh Of The Commonwealth System Of Higher Education IRAP gene as treatment for arthritis
US6156304A (en) * 1990-12-20 2000-12-05 University Of Pittsburgh Of The Commonwealth System Of Higher Education Gene transfer for studying and treating a connective tissue of a mammalian host
US6159464A (en) * 1990-12-20 2000-12-12 University Of Pittsburgh Of The Commonwealth System Of Higher Education Viral vectors to inhibit leukocyte infiltration or cartilage degradation of joints
WO1992012154A1 (fr) * 1990-12-31 1992-07-23 Fujisawa Pharmaceutical Co., Ltd. Derive d'immidazotriazine
US5356897A (en) * 1991-09-09 1994-10-18 Fujisawa Pharmaceutical Co., Ltd. 3-(heteroaryl)-pyrazololi[1,5-a]pyrimidines
US5783664A (en) * 1993-09-17 1998-07-21 Smithkline Beecham Corporation Cytokine suppressive anit-inflammatory drug binding proteins
DK0724588T3 (da) * 1993-09-17 2000-05-15 Smithkline Beecham Corp Lægemiddelbindende protein
US5552422A (en) * 1995-01-11 1996-09-03 Merck Frosst Canada, Inc. Aryl substituted 5,5 fused aromatic nitrogen compounds as anti-inflammatory agents
ATE264318T1 (de) 1996-11-19 2004-04-15 Amgen Inc Aryl und heteroaryl substituierte kondensierte pyrrole als entzündunghemmende mittel
AR015425A1 (es) * 1997-09-05 2001-05-02 Smithkline Beecham Corp Compuestos de benzotiazol, composicion farmaceutica que los contiene, su uso en la manufactura de un medicamento, procedimiento para su preparacion,compuestos intermediarios y procedimiento para su preparacion
US6930101B1 (en) 1999-05-17 2005-08-16 The Regents Of The University Of California Thiazolopyrimidines useful as TNFα inhibitors
CN1518550A (zh) * 2001-06-21 2004-08-04 ʷ��˿�������ȳ�ķ���޹�˾ 用于预防和治疗疱疹病毒感染的咪唑并[1,2-a]吡啶衍生物
EP1432712B1 (fr) 2001-10-05 2006-05-17 SmithKline Beecham Corporation Derives imidazo-pyridine destines au traitement d'infection virale herpetique
CA2526285A1 (fr) 2003-05-15 2004-12-23 Arqule, Inc. Inhibiteurs de p38 et leurs methodes d'utilisation
WO2006010082A1 (fr) * 2004-07-08 2006-01-26 Arqule, Inc. Naphtalenes disubstitues en position 1,4 utilises comme inhibiteurs de map kinase p38
JP2008517064A (ja) * 2004-10-19 2008-05-22 アークル インコーポレイテッド Ｐ３８ｍａｐキナーゼのイミダゾオキサゾールおよびイミダゾチアゾール阻害剤の合成
JP2012511021A (ja) * 2008-12-05 2012-05-17 アークル インコーポレイテッド Ｒａｆの阻害剤およびその使用
NZ624963A (en) 2009-04-29 2016-07-29 Amarin Pharmaceuticals Ie Ltd Pharmaceutical compositions comprising epa and a cardiovascular agent and methods of using the same
GB201321743D0 (en) 2013-12-09 2014-01-22 Ucb Pharma Sa Therapeutic agents

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1541321A (en) * 1976-03-10 1979-02-28 Metabio 2,3-dihydroimidazo(2,1-b)thiazole derivatives and process for their preparation
US4064260A (en) * 1976-07-29 1977-12-20 E. I. Du Pont De Nemours And Company Anti-inflammatory diarylimidazothiazoles and their corresponding S-oxides
US4263311A (en) * 1976-09-27 1981-04-21 Smithkline Corporation 5,6-Phenyl-2,3-dihydroimidazo [2,1-b] thiazoles
US4153706A (en) * 1978-02-13 1979-05-08 Smithkline Corporation 6-Hydroxy-5,6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazoles
US4175127A (en) * 1978-09-27 1979-11-20 Smithkline Corporation Pyridyl substituted 2,3-dihydroimidazo[2,1-b]thiazoles
GB2039882A (en) * 1979-01-05 1980-08-20 Ciba Geigy Ag Bicyclic thiadiaza compounds and their use as medicaments
US4186205A (en) * 1979-01-08 1980-01-29 Smithkline Corporation 2,3-Di(4-substituted phenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazoles
US4507481A (en) * 1983-07-29 1985-03-26 Pennwalt Corporation Pyrrolo[1,2-a]imidazoles and imidazo[1,2-a]pyridines

Also Published As

Publication number Publication date
AU7880087A (en) 1988-03-08
US4794114A (en) 1988-12-27
EP0321490B1 (fr) 1994-06-22
CA1292694C (fr) 1991-12-03
DK199788D0 (da) 1988-04-12
JPH01503782A (ja) 1989-12-21
DE3750140D1 (de) 1994-07-28
EP0321490A1 (fr) 1989-06-28
ATE107507T1 (de) 1994-07-15
GR871277B (en) 1987-12-18
EP0321490A4 (fr) 1990-05-14
WO1988001169A1 (fr) 1988-02-25

Similar Documents

Publication Publication Date Title
DK199788D0 (da) Haemning af interleukin-1 produktion af monocytter og/eller makrofager
DE3884607D1 (de) Ausgangsrechnungsabwicklungssystem und -verfahren.
DE3676906D1 (de) Laserbearbeitungsverfahren.
DE3586959D1 (de) Desinfektionsverfahren sowie zusammensetzung dafuer.
NO861879L (no) Broennloggesonde.
DE3786229D1 (de) Prolinalderivate.
IT8521865A0 (it) Derivati di etilendiamminomonoammidi.
IT8521234A0 (it) Derivati pirrolidonici.
IT8619481A0 (it) Derivati eterociclici.
IT8720982A0 (it) P-amminofenoli loro derivati emetodo di utilizzazione.
IT1230084B (it) Derivati imidazolici e procedimento per il loro ottenimento.
IT208051Z2 (it) Cuscinetto con complesso di tenuta perfezionato
IT8522392A0 (it) Pantotenil derivati.
DE58905016D1 (de) Digitalisier-verfahren und -anordnung.
IT1216999B (it) Derivati di prolina.
IT1189880B (it) Uscita semplice e completa per cassetti
NO875223D0 (no) Vannutkaster for montering i en yttervegg.
NO163012C (no) Racemiske og optisk aktive 14-hydroxy-imino-eburnanderivater.
IT1168573B (it) Metodo per impiallacciare cornici, e cornici ottenute con tale metodo
DK565588D0 (da) Stige, navnlig til montering i broendakse
IT8821862A0 (it) Derivati imidazolinici di diidronaftalene e tetraidronaftalene.
DK201480A (da) Baerebeslag til rullestokke
IT209868Z2 (it) Protesi dentale, con vite interamente sommersa.
FR2607858B1 (fr) Caveau funeraire
NO892923D0 (no) Skjaereelementer for borkrone og borkrone med slike elementer.

Legal Events

Date Code Title Description
AHB Application shelved due to non-payment