DK1989217T5 - 11-Phospor-steroidderivater, der er anvendelige som progesteronreceptormodulatorer - Google Patents

11-Phospor-steroidderivater, der er anvendelige som progesteronreceptormodulatorer

Info

Publication number
DK1989217T5
DK1989217T5 DK07757084.4T DK07757084T DK1989217T5 DK 1989217 T5 DK1989217 T5 DK 1989217T5 DK 07757084 T DK07757084 T DK 07757084T DK 1989217 T5 DK1989217 T5 DK 1989217T5
Authority
DK
Denmark
Prior art keywords
phospor
receptor modulators
progesterone receptor
derivatives useful
steroid derivatives
Prior art date
Application number
DK07757084.4T
Other languages
English (en)
Other versions
DK1989217T3 (da
Inventor
Weiqin Jiang
Zhihua Sui
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Application granted granted Critical
Publication of DK1989217T3 publication Critical patent/DK1989217T3/da
Publication of DK1989217T5 publication Critical patent/DK1989217T5/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/36—Antigestagens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pregnancy & Childbirth (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
DK07757084.4T 2006-02-17 2007-02-16 11-Phospor-steroidderivater, der er anvendelige som progesteronreceptormodulatorer DK1989217T5 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US77473506P 2006-02-17 2006-02-17
PCT/US2007/062272 WO2007098381A2 (en) 2006-02-17 2007-02-16 11-phosphorous steroid derivatives useful as progesterone receptor modulators

Publications (2)

Publication Number Publication Date
DK1989217T3 DK1989217T3 (da) 2012-10-08
DK1989217T5 true DK1989217T5 (da) 2013-01-14

Family

ID=38438062

Family Applications (1)

Application Number Title Priority Date Filing Date
DK07757084.4T DK1989217T5 (da) 2006-02-17 2007-02-16 11-Phospor-steroidderivater, der er anvendelige som progesteronreceptormodulatorer

Country Status (14)

Country Link
US (1) US7678781B2 (da)
EP (1) EP1989217B1 (da)
JP (1) JP5230449B2 (da)
CN (1) CN101415720B (da)
AU (1) AU2007217094A1 (da)
CA (1) CA2642829A1 (da)
CY (1) CY1113146T1 (da)
DK (1) DK1989217T5 (da)
ES (1) ES2388752T3 (da)
HK (2) HK1125652A1 (da)
PL (1) PL1989217T4 (da)
PT (1) PT1989217E (da)
SI (1) SI1989217T1 (da)
WO (1) WO2007098381A2 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2680119A1 (en) * 2007-03-07 2008-09-12 Janssen Pharmaceutica N.V. Steroids derivatives as selective progesterone receptor modulators
CN101926806A (zh) * 2009-06-24 2010-12-29 天津金耀集团有限公司 一种17磷类雌甾化合物在制备紧急避孕药物中的应用
CN102617691B (zh) * 2012-01-18 2014-05-14 上海新华联制药有限公司 一种改进的米非司酮中间体制备方法
WO2014060888A1 (en) 2012-10-18 2014-04-24 Lupin Limited Novel process and intermediate for preparation of ulipristal
US10786461B2 (en) 2014-11-17 2020-09-29 Context Biopharma Inc. Onapristone extended-release compositions and methods
BR112018005999A2 (pt) 2015-09-25 2019-01-08 Context Biopharma Inc métodos para a produção de intermediários de onapristona
KR20180113988A (ko) 2015-12-15 2018-10-17 컨텍스트 바이오파마 인코포레이티드 비정질 오나프리스톤 조성물 및 그 제조방법
US20180148471A1 (en) 2016-11-30 2018-05-31 Arno Therapeutics, Inc. Methods for onapristone synthesis dehydration and deprotection
WO2023000135A1 (en) * 2021-07-19 2023-01-26 Context Biopharma Inc. Processes of making onapristone and intermediates thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9003939D0 (en) * 1990-02-21 1990-04-18 Imperial College Sulphatase inhibitors
ZA929315B (en) * 1991-12-20 1993-05-24 Akzo Nv 17-spirofuran-3'-ylidene steroids.
CA2100514C (en) 1992-07-29 2005-03-29 Johannes A. M. Hamersma 17-spiromethylene steroids
JPH0995496A (ja) * 1995-09-28 1997-04-08 Kaken Pharmaceut Co Ltd ウルソデオキシコール酸誘導体
EP1448592B1 (en) * 2001-10-18 2006-03-08 Sterix Limited Steroidal compounds for inhibiting steroid sulphatase
DK1989218T3 (da) 2006-02-17 2010-04-26 Janssen Pharmaceutica Nv 17-phosphor-steroidderivater, der er anvendelige som progesteronreceptormodulatorer

Also Published As

Publication number Publication date
WO2007098381A2 (en) 2007-08-30
AU2007217094A1 (en) 2007-08-30
EP1989217B1 (en) 2012-06-27
SI1989217T1 (sl) 2012-09-28
PT1989217E (pt) 2012-08-30
PL1989217T3 (pl) 2012-11-30
ES2388752T3 (es) 2012-10-18
CN101415720A (zh) 2009-04-22
JP2009527489A (ja) 2009-07-30
US20070232570A1 (en) 2007-10-04
US7678781B2 (en) 2010-03-16
WO2007098381A3 (en) 2008-01-03
HK1131396A1 (en) 2010-01-22
PL1989217T4 (pl) 2013-02-28
CN101415720B (zh) 2011-10-05
DK1989217T3 (da) 2012-10-08
EP1989217A2 (en) 2008-11-12
JP5230449B2 (ja) 2013-07-10
CA2642829A1 (en) 2007-08-30
CY1113146T1 (el) 2016-04-13
HK1125652A1 (en) 2009-08-14

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