HK1125652A1 - 11-phosphorous steroid derivatives useful as progesterone receptor modulators - Google Patents

11-phosphorous steroid derivatives useful as progesterone receptor modulators

Info

Publication number
HK1125652A1
HK1125652A1 HK09104217.0A HK09104217A HK1125652A1 HK 1125652 A1 HK1125652 A1 HK 1125652A1 HK 09104217 A HK09104217 A HK 09104217A HK 1125652 A1 HK1125652 A1 HK 1125652A1
Authority
HK
Hong Kong
Prior art keywords
receptor modulators
progesterone receptor
derivatives useful
steroid derivatives
phosphorous
Prior art date
Application number
HK09104217.0A
Other languages
English (en)
Inventor
Weiqin Jiang
Zhihua Sui
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of HK1125652A1 publication Critical patent/HK1125652A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/36—Antigestagens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pregnancy & Childbirth (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
HK09104217.0A 2006-02-17 2009-05-07 11-phosphorous steroid derivatives useful as progesterone receptor modulators HK1125652A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US77473506P 2006-02-17 2006-02-17
PCT/US2007/062272 WO2007098381A2 (en) 2006-02-17 2007-02-16 11-phosphorous steroid derivatives useful as progesterone receptor modulators

Publications (1)

Publication Number Publication Date
HK1125652A1 true HK1125652A1 (en) 2009-08-14

Family

ID=38438062

Family Applications (2)

Application Number Title Priority Date Filing Date
HK09104217.0A HK1125652A1 (en) 2006-02-17 2009-05-07 11-phosphorous steroid derivatives useful as progesterone receptor modulators
HK09109627.3A HK1131396A1 (en) 2006-02-17 2009-10-19 11-phosphorous steroid derivatives useful as progesterone receptor modulators

Family Applications After (1)

Application Number Title Priority Date Filing Date
HK09109627.3A HK1131396A1 (en) 2006-02-17 2009-10-19 11-phosphorous steroid derivatives useful as progesterone receptor modulators

Country Status (14)

Country Link
US (1) US7678781B2 (da)
EP (1) EP1989217B1 (da)
JP (1) JP5230449B2 (da)
CN (1) CN101415720B (da)
AU (1) AU2007217094A1 (da)
CA (1) CA2642829A1 (da)
CY (1) CY1113146T1 (da)
DK (1) DK1989217T5 (da)
ES (1) ES2388752T3 (da)
HK (2) HK1125652A1 (da)
PL (1) PL1989217T4 (da)
PT (1) PT1989217E (da)
SI (1) SI1989217T1 (da)
WO (1) WO2007098381A2 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7981927B2 (en) * 2007-03-07 2011-07-19 Janssen Pharmaceutica N.V. Steroids derivatives as selective progesterone receptor modulators
CN101926806A (zh) * 2009-06-24 2010-12-29 天津金耀集团有限公司 一种17磷类雌甾化合物在制备紧急避孕药物中的应用
CN102617691B (zh) * 2012-01-18 2014-05-14 上海新华联制药有限公司 一种改进的米非司酮中间体制备方法
WO2014060888A1 (en) 2012-10-18 2014-04-24 Lupin Limited Novel process and intermediate for preparation of ulipristal
MX2017005163A (es) 2014-11-17 2018-01-18 Arno Therapeutics Inc Composiciones de liberación prolongada de onapristona y métodos.
CA2998924A1 (en) * 2015-09-25 2017-03-30 Context Biopharma Inc. Methods of making onapristone intermediates
MX2018007154A (es) 2015-12-15 2019-01-10 Context Biopharma Inc Composiciones de onapristona amorfa y metodos para hacer las mismas.
US20180148471A1 (en) 2016-11-30 2018-05-31 Arno Therapeutics, Inc. Methods for onapristone synthesis dehydration and deprotection
WO2023000135A1 (en) * 2021-07-19 2023-01-26 Context Biopharma Inc. Processes of making onapristone and intermediates thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9003939D0 (en) * 1990-02-21 1990-04-18 Imperial College Sulphatase inhibitors
ZA929315B (en) * 1991-12-20 1993-05-24 Akzo Nv 17-spirofuran-3'-ylidene steroids.
CA2100514C (en) * 1992-07-29 2005-03-29 Johannes A. M. Hamersma 17-spiromethylene steroids
JPH0995496A (ja) * 1995-09-28 1997-04-08 Kaken Pharmaceut Co Ltd ウルソデオキシコール酸誘導体
PT1448592E (pt) * 2001-10-18 2006-07-31 Sterix Ltd Compostos esteroides para inibicao da esteroide sulfatase
PL1989218T3 (pl) * 2006-02-17 2010-06-30 Janssen Pharmaceutica Nv Pochodne 17-fosforosteroidów użyteczne jako modulatory receptora progesteronowego

Also Published As

Publication number Publication date
JP5230449B2 (ja) 2013-07-10
WO2007098381A2 (en) 2007-08-30
AU2007217094A1 (en) 2007-08-30
EP1989217A2 (en) 2008-11-12
WO2007098381A3 (en) 2008-01-03
HK1131396A1 (en) 2010-01-22
CN101415720A (zh) 2009-04-22
CY1113146T1 (el) 2016-04-13
SI1989217T1 (sl) 2012-09-28
JP2009527489A (ja) 2009-07-30
DK1989217T3 (da) 2012-10-08
PL1989217T4 (pl) 2013-02-28
PL1989217T3 (pl) 2012-11-30
ES2388752T3 (es) 2012-10-18
US20070232570A1 (en) 2007-10-04
CN101415720B (zh) 2011-10-05
CA2642829A1 (en) 2007-08-30
EP1989217B1 (en) 2012-06-27
PT1989217E (pt) 2012-08-30
DK1989217T5 (da) 2013-01-14
US7678781B2 (en) 2010-03-16

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20170216