DK19784A - Fremgangsmaade til fremstilling af 2-substituerede 5-nitroso-4,6-diamino-pyrimidiner - Google Patents
Fremgangsmaade til fremstilling af 2-substituerede 5-nitroso-4,6-diamino-pyrimidiner Download PDFInfo
- Publication number
- DK19784A DK19784A DK19784A DK19784A DK19784A DK 19784 A DK19784 A DK 19784A DK 19784 A DK19784 A DK 19784A DK 19784 A DK19784 A DK 19784A DK 19784 A DK19784 A DK 19784A
- Authority
- DK
- Denmark
- Prior art keywords
- pyrimidines
- nitroso
- diamino
- substituted
- preparing
- Prior art date
Links
- 229940058936 antimalarials diaminopyrimidines Drugs 0.000 title 1
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 239000000543 intermediate Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 150000002826 nitrites Chemical class 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/50—Three nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Plural Heterocyclic Compounds (AREA)
Description
pUpi alkohol 1 surt i nærværelse af et nitritsalt til det 111overende omidinsalt af isonitrosomalonitril, som opvarmet» 1 dimethyl formamid i basisk miljø.
Forbindelserne I kan anvendes som mellemprodukter, f.eks. til fremstilling af lægemidler og farvestofkomponenter.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH48283 | 1983-01-28 | ||
| CH48283A CH660589A5 (de) | 1983-01-28 | 1983-01-28 | Verfahren zur herstellung von 2-substituierten 5-nitroso-4,6-diamino-pyrimidinen. |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| DK19784D0 DK19784D0 (da) | 1984-01-17 |
| DK19784A true DK19784A (da) | 1984-07-29 |
| DK159681B DK159681B (da) | 1990-11-19 |
| DK159681C DK159681C (da) | 1991-04-29 |
Family
ID=4188010
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK19784A DK159681C (da) | 1983-01-28 | 1984-01-17 | Fremgangsmaade til fremstilling af 2-substituerede 5-nitroso-4,6-diamino-pyrimidiner |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0115325B1 (da) |
| JP (1) | JPS59141566A (da) |
| CA (1) | CA1241958A (da) |
| CH (1) | CH660589A5 (da) |
| DE (1) | DE3465083D1 (da) |
| DK (1) | DK159681C (da) |
| IE (1) | IE56419B1 (da) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH667089A5 (de) * | 1985-12-06 | 1988-09-15 | Lonza Ag | Verfahren zur herstellung von 2-substituierten 5-nitroso-4,6-diamino-pyrimidinen. |
| JPH02225474A (ja) * | 1989-01-04 | 1990-09-07 | Lonza Ag | 2,4―ジアミノ―6―ピペリジニル―ピリミジン―3―n―オキシドの製造方法 |
| SK285728B6 (sk) * | 1999-04-15 | 2007-07-06 | Basf Aktiengesellschaft | Spôsob prípravy substituovaných pyrimidínov |
| US6281358B1 (en) | 1999-04-15 | 2001-08-28 | American Cyanamid Company | Process for the preparation of substituted pyrimidines |
| DE10024886A1 (de) * | 2000-05-19 | 2001-11-22 | Henkel Kgaa | Mittel zum Färben von keratinhaltigen Fasern |
| CN119371358A (zh) * | 2024-10-22 | 2025-01-28 | 湖南吴赣药业有限公司 | 一种2,4-二氨基-6-羟基-5-亚硝基嘧啶制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1364734A (fr) * | 1963-05-15 | 1964-06-26 | Lumiere Lab | Procédé de préparation de dérivés acyclique et cyclique de la guanidine |
| DE2651794C2 (de) * | 1976-11-12 | 1982-09-23 | Henkel KGaA, 4000 Düsseldorf | Verfahren zur Herstellung von 5-Nitroso-2,4,6-triaminopyrimidin |
| JPS5818367A (ja) * | 1981-07-27 | 1983-02-02 | Kohjin Co Ltd | ニトロソピリミジン誘導体の製造方法 |
-
1983
- 1983-01-28 CH CH48283A patent/CH660589A5/de not_active IP Right Cessation
- 1983-12-12 IE IE292683A patent/IE56419B1/en not_active IP Right Cessation
-
1984
- 1984-01-17 DK DK19784A patent/DK159681C/da active
- 1984-01-18 CA CA000445565A patent/CA1241958A/en not_active Expired
- 1984-01-24 EP EP84100718A patent/EP0115325B1/de not_active Expired
- 1984-01-24 DE DE8484100718T patent/DE3465083D1/de not_active Expired
- 1984-01-27 JP JP1216784A patent/JPS59141566A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| DK159681B (da) | 1990-11-19 |
| DK19784D0 (da) | 1984-01-17 |
| EP0115325A3 (en) | 1984-09-12 |
| EP0115325B1 (de) | 1987-07-29 |
| EP0115325A2 (de) | 1984-08-08 |
| CH660589A5 (de) | 1987-05-15 |
| CA1241958A (en) | 1988-09-13 |
| DE3465083D1 (en) | 1987-09-03 |
| IE56419B1 (en) | 1991-07-31 |
| DK159681C (da) | 1991-04-29 |
| JPS59141566A (ja) | 1984-08-14 |
| IE832926L (en) | 1984-07-28 |
| JPH0549666B2 (da) | 1993-07-26 |
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