DK1948166T3 - Carbazolderivater som funktionelle 5-HT6-ligander - Google Patents
Carbazolderivater som funktionelle 5-HT6-liganderInfo
- Publication number
- DK1948166T3 DK1948166T3 DK06766266.8T DK06766266T DK1948166T3 DK 1948166 T3 DK1948166 T3 DK 1948166T3 DK 06766266 T DK06766266 T DK 06766266T DK 1948166 T3 DK1948166 T3 DK 1948166T3
- Authority
- DK
- Denmark
- Prior art keywords
- carbazole derivatives
- receptor
- ligands
- functional
- stereoisomers
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/82—Carbazoles; Hydrogenated carbazoles
- C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/94—[b, c]- or [b, d]-condensed containing carbocyclic rings other than six-membered
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Physical Education & Sports Medicine (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Child & Adolescent Psychology (AREA)
- Anesthesiology (AREA)
- Vascular Medicine (AREA)
- Nutrition Science (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
- Indole Compounds (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Photoreceptors In Electrophotography (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN1504CH2005 | 2005-10-19 | ||
| PCT/IN2006/000195 WO2007046111A1 (en) | 2005-10-19 | 2006-06-09 | Carbazole derivatives as functional 5-ht6 ligands |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1948166T3 true DK1948166T3 (da) | 2011-01-31 |
Family
ID=37054637
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK06766266.8T DK1948166T3 (da) | 2005-10-19 | 2006-06-09 | Carbazolderivater som funktionelle 5-HT6-ligander |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US8143303B2 (da) |
| EP (1) | EP1948166B1 (da) |
| JP (1) | JP2009512681A (da) |
| KR (1) | KR101125820B1 (da) |
| CN (1) | CN101291670B (da) |
| AT (1) | ATE485040T1 (da) |
| AU (1) | AU2006305502B2 (da) |
| BR (1) | BRPI0619308A2 (da) |
| CA (1) | CA2626646C (da) |
| CY (1) | CY1111560T1 (da) |
| DE (1) | DE602006017722D1 (da) |
| DK (1) | DK1948166T3 (da) |
| EA (1) | EA014694B1 (da) |
| ES (1) | ES2354455T3 (da) |
| HK (1) | HK1120424A1 (da) |
| HR (1) | HRP20110041T1 (da) |
| NO (1) | NO341252B1 (da) |
| NZ (1) | NZ567865A (da) |
| PL (1) | PL1948166T3 (da) |
| PT (1) | PT1948166E (da) |
| RS (1) | RS51627B (da) |
| SI (1) | SI1948166T1 (da) |
| WO (1) | WO2007046111A1 (da) |
| ZA (1) | ZA200803118B (da) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013055386A2 (en) * | 2011-10-03 | 2013-04-18 | The University Of Utah Research Foundation | Application of 5-ht6 receptor antagonists for the alleviation of cognitive deficits of down syndrome |
| CN106045972B (zh) * | 2016-06-03 | 2018-11-16 | 中山大学 | 咔唑-利凡斯的明二联体及其药物组合物和应用 |
| CN106749184B (zh) * | 2016-11-15 | 2020-07-17 | 中山大学 | 8-氨基喹啉-羟基咔唑杂联体，其制备方法及其药物组合物 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA01005905A (es) * | 1998-12-11 | 2002-09-18 | Univ Virginia Commonwealth | Ligandos selectivos de receptores de 5-ht6. |
| MXPA04003419A (es) * | 2001-10-09 | 2004-07-08 | Upjohn Co | Tetrahidro y hexahidro-carbazoles sustituidos con arilsulfonilo como ligandos del receptor 5-ht-6. |
-
2006
- 2006-06-09 DE DE602006017722T patent/DE602006017722D1/de active Active
- 2006-06-09 EP EP06766266A patent/EP1948166B1/en active Active
- 2006-06-09 NZ NZ567865A patent/NZ567865A/en not_active IP Right Cessation
- 2006-06-09 CA CA2626646A patent/CA2626646C/en not_active Expired - Fee Related
- 2006-06-09 US US12/083,707 patent/US8143303B2/en not_active Expired - Fee Related
- 2006-06-09 PT PT06766266T patent/PT1948166E/pt unknown
- 2006-06-09 CN CN2006800390082A patent/CN101291670B/zh not_active Expired - Fee Related
- 2006-06-09 BR BRPI0619308-0A patent/BRPI0619308A2/pt not_active Application Discontinuation
- 2006-06-09 ES ES06766266T patent/ES2354455T3/es active Active
- 2006-06-09 EA EA200801114A patent/EA014694B1/ru not_active IP Right Cessation
- 2006-06-09 RS RS20110017A patent/RS51627B/en unknown
- 2006-06-09 DK DK06766266.8T patent/DK1948166T3/da active
- 2006-06-09 PL PL06766266T patent/PL1948166T3/pl unknown
- 2006-06-09 AT AT06766266T patent/ATE485040T1/de active
- 2006-06-09 KR KR1020087010404A patent/KR101125820B1/ko active IP Right Grant
- 2006-06-09 WO PCT/IN2006/000195 patent/WO2007046111A1/en active Application Filing
- 2006-06-09 AU AU2006305502A patent/AU2006305502B2/en not_active Ceased
- 2006-06-09 JP JP2008536206A patent/JP2009512681A/ja active Pending
- 2006-06-09 SI SI200630873T patent/SI1948166T1/sl unknown
-
2008
- 2008-04-09 NO NO20081739A patent/NO341252B1/no not_active IP Right Cessation
- 2008-04-09 ZA ZA2008/03118A patent/ZA200803118B/en unknown
- 2008-12-03 HK HK08113183.2A patent/HK1120424A1/xx not_active IP Right Cessation
-
2011
- 2011-01-20 CY CY20111100064T patent/CY1111560T1/el unknown
- 2011-01-20 HR HR20110041T patent/HRP20110041T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2009512681A (ja) | 2009-03-26 |
| CA2626646C (en) | 2011-03-01 |
| CA2626646A1 (en) | 2007-04-26 |
| DE602006017722D1 (de) | 2010-12-02 |
| NZ567865A (en) | 2010-07-30 |
| US20100189646A1 (en) | 2010-07-29 |
| KR20080064848A (ko) | 2008-07-09 |
| ZA200803118B (en) | 2011-11-30 |
| CN101291670B (zh) | 2012-07-04 |
| EP1948166A1 (en) | 2008-07-30 |
| EP1948166B1 (en) | 2010-10-20 |
| HRP20110041T1 (hr) | 2011-02-28 |
| PL1948166T3 (pl) | 2011-04-29 |
| RS51627B (en) | 2011-08-31 |
| US8143303B2 (en) | 2012-03-27 |
| KR101125820B1 (ko) | 2012-03-28 |
| NO341252B1 (no) | 2017-09-25 |
| HK1120424A1 (en) | 2009-04-03 |
| CN101291670A (zh) | 2008-10-22 |
| NO20081739L (no) | 2008-07-09 |
| WO2007046111A1 (en) | 2007-04-26 |
| CY1111560T1 (el) | 2015-10-07 |
| SI1948166T1 (sl) | 2011-02-28 |
| ATE485040T1 (de) | 2010-11-15 |
| AU2006305502A1 (en) | 2007-04-26 |
| EA014694B1 (ru) | 2010-12-30 |
| PT1948166E (pt) | 2011-01-19 |
| ES2354455T3 (es) | 2011-03-15 |
| BRPI0619308A2 (pt) | 2013-03-05 |
| EA200801114A1 (ru) | 2009-02-27 |
| AU2006305502B2 (en) | 2009-11-26 |
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