DK1904529T3 - Anvendelse af Stefin A som et scaffoldprotein - Google Patents

Anvendelse af Stefin A som et scaffoldprotein

Info

Publication number
DK1904529T3
DK1904529T3 DK06744166.7T DK06744166T DK1904529T3 DK 1904529 T3 DK1904529 T3 DK 1904529T3 DK 06744166 T DK06744166 T DK 06744166T DK 1904529 T3 DK1904529 T3 DK 1904529T3
Authority
DK
Denmark
Prior art keywords
stefin
scaffold
scaffold protein
mutations
relates
Prior art date
Application number
DK06744166.7T
Other languages
Danish (da)
English (en)
Inventor
Robbie Woodman
Johannes Tsung-Han Yeh
Sophie Laurenson
Ferrigno Paul Ko
Original Assignee
Medical Res Council
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0511873A external-priority patent/GB0511873D0/en
Priority claimed from GB0608836A external-priority patent/GB0608836D0/en
Application filed by Medical Res Council filed Critical Medical Res Council
Application granted granted Critical
Publication of DK1904529T3 publication Critical patent/DK1904529T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/8139—Cysteine protease (E.C. 3.4.22) inhibitors, e.g. cystatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1044—Preparation or screening of libraries displayed on scaffold proteins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DK06744166.7T 2005-06-10 2006-06-08 Anvendelse af Stefin A som et scaffoldprotein DK1904529T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0511873A GB0511873D0 (en) 2005-06-10 2005-06-10 Scaffold
GB0608836A GB0608836D0 (en) 2006-05-04 2006-05-04 Scaffold
PCT/GB2006/002115 WO2006131749A2 (en) 2005-06-10 2006-06-08 Scaffold

Publications (1)

Publication Number Publication Date
DK1904529T3 true DK1904529T3 (da) 2010-11-15

Family

ID=37314237

Family Applications (1)

Application Number Title Priority Date Filing Date
DK06744166.7T DK1904529T3 (da) 2005-06-10 2006-06-08 Anvendelse af Stefin A som et scaffoldprotein

Country Status (9)

Country Link
US (2) US8063019B2 (https=)
EP (1) EP1904529B1 (https=)
JP (1) JP4989638B2 (https=)
AT (1) ATE477272T1 (https=)
AU (1) AU2006256530B2 (https=)
CA (1) CA2610976C (https=)
DE (1) DE602006016133D1 (https=)
DK (1) DK1904529T3 (https=)
WO (1) WO2006131749A2 (https=)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4989638B2 (ja) * 2005-06-10 2012-08-01 メディカル リサーチ カウンシル 足場
GB0807065D0 (en) 2008-04-18 2008-05-21 Univ Leeds Novel scaffolds
GB201302597D0 (en) * 2013-02-14 2013-04-03 Univ Leeds Novel Synthetic Proteins
JP6655074B2 (ja) * 2014-06-20 2020-02-26 ジェネンテック， インコーポレイテッド シャガシンに基づく足場組成物、方法及び使用
EP3405579A1 (en) 2016-01-22 2018-11-28 Modernatx, Inc. Messenger ribonucleic acids for the production of intracellular binding polypeptides and methods of use thereof
ES3026859T3 (en) 2017-01-04 2025-06-12 Mgi Tech Co Ltd Stepwise sequencing by non-labeled reversible terminators or natural nucleotides
KR102582297B1 (ko) 2017-05-19 2023-09-25 필립모리스 프로덕츠 에스.에이. 대상체의 흡연 상태를 구별하기 위한 진단 테스트
GB201710973D0 (en) 2017-07-07 2017-08-23 Avacta Life Sciences Ltd Scaffold proteins
CN114761431B (zh) * 2019-10-16 2025-04-25 株式会社Lg化学 新生儿Fc受体结合AFFIMER
GB202101299D0 (en) 2020-06-09 2021-03-17 Avacta Life Sciences Ltd Diagnostic polypetides and methods
US20230366023A1 (en) 2020-10-09 2023-11-16 Bgi Shenzhen Co., Ltd. Methods and compositions for bioluminescence-based sequencing
CN119213021A (zh) * 2022-02-10 2024-12-27 艾菲赛尔治疗株式会社 与CD40L特异性结合的Stefin A蛋白变体及其用途
US20250346630A1 (en) * 2022-03-24 2025-11-13 Agency For Science, Technology And Research Engineering Peptides Using Peptide Epitope Linker Evolution
WO2024141788A1 (en) * 2022-12-29 2024-07-04 Affyxell Therapeutics Co., Ltd. Genetically modified stem cells expressing exogenous binding agents and uses thereof
GB202403780D0 (en) 2024-03-15 2024-05-01 Avacta Life Sciences Ltd Polypeptides and methods for detecting and quantifying small molecules

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2205356A1 (en) * 1994-11-21 1996-05-30 Peter Edward Urwin Modified proteinase inhibitors
NZ509013A (en) * 1998-07-20 2002-12-20 Inoxell As Novel methods for the identification of ligand and target biomolecules
ATE482972T1 (de) * 2003-11-06 2010-10-15 Danisco Us Inc Tgf-beta1-bindende und geträgerte peptide
JP4989638B2 (ja) * 2005-06-10 2012-08-01 メディカル リサーチ カウンシル 足場

Also Published As

Publication number Publication date
JP4989638B2 (ja) 2012-08-01
US8063019B2 (en) 2011-11-22
US20120190819A1 (en) 2012-07-26
JP2008541776A (ja) 2008-11-27
ATE477272T1 (de) 2010-08-15
US8481491B2 (en) 2013-07-09
DE602006016133D1 (de) 2010-09-23
EP1904529B1 (en) 2010-08-11
AU2006256530A1 (en) 2006-12-14
WO2006131749A3 (en) 2007-05-18
CA2610976C (en) 2020-11-24
EP1904529A2 (en) 2008-04-02
AU2006256530B2 (en) 2012-12-20
US20080207509A1 (en) 2008-08-28
CA2610976A1 (en) 2006-12-14
WO2006131749A2 (en) 2006-12-14

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