DK189686A - Carbapenemforbindelser og fremgangsmaade til fremstilling deraf samt middel indeholdende forbindelserne - Google Patents

Carbapenemforbindelser og fremgangsmaade til fremstilling deraf samt middel indeholdende forbindelserne Download PDF

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Publication number
DK189686A
DK189686A DK189686A DK189686A DK189686A DK 189686 A DK189686 A DK 189686A DK 189686 A DK189686 A DK 189686A DK 189686 A DK189686 A DK 189686A DK 189686 A DK189686 A DK 189686A
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sup
group
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hydrogen atom
compounds
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DK189686A
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English (en)
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DK189686D0 (da
Inventor
Isao Kawamoto
Rokuro Endo
Masayuki Iwata
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Sankyo Co
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Publication date
Application filed by Sankyo Co filed Critical Sankyo Co
Publication of DK189686D0 publication Critical patent/DK189686D0/da
Publication of DK189686A publication Critical patent/DK189686A/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)

Description

hvori Z betegner et oxygenatom eller to hydrogenatomer, R^· betegner et hydrogenatom, en C^^-alkylgruppe, en alkanoylgruppe eller en Cj^-alkansulfonylgruppe, 2 R betegner et hydrogenatom eller en hydroxygruppe, og R betegner en carbamoylgruppe, 2 3 eller R betegner en carbamoyloxygruppe, og R betegner et hydrogenatom eller en carbamoylgruppe, 4 r betegner et hydrogenatom eller en Cj^-alkylgruppe, og
Figure DK189686AD00021
betegner en 4-6-leddet mættet heterocyklisk gruppe hvori det angivne nitrogenatom er det eneste heteroatom, eller et farmaceutisk acceptabelt salt eller en farmaceutisk acceptabel ester deraf.
DK189686A 1985-04-27 1986-04-24 Carbapenemforbindelser og fremgangsmaade til fremstilling deraf samt middel indeholdende forbindelserne DK189686A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP9198885 1985-04-27
JP9198885 1985-04-27

Publications (2)

Publication Number Publication Date
DK189686D0 DK189686D0 (da) 1986-04-24
DK189686A true DK189686A (da) 1986-10-28

Family

ID=14041841

Family Applications (1)

Application Number Title Priority Date Filing Date
DK189686A DK189686A (da) 1985-04-27 1986-04-24 Carbapenemforbindelser og fremgangsmaade til fremstilling deraf samt middel indeholdende forbindelserne

Country Status (17)

Country Link
US (1) US4771046A (da)
EP (1) EP0202048B1 (da)
JP (1) JPH0710868B2 (da)
KR (1) KR920010076B1 (da)
AT (1) ATE69053T1 (da)
AU (1) AU583113B2 (da)
CA (1) CA1305709C (da)
DE (1) DE3682225D1 (da)
DK (1) DK189686A (da)
ES (1) ES8800952A1 (da)
FI (1) FI81577C (da)
HU (1) HU194882B (da)
IE (1) IE58892B1 (da)
NO (1) NO163452C (da)
NZ (1) NZ215957A (da)
PH (1) PH22555A (da)
ZA (1) ZA863109B (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0759581B2 (ja) * 1986-09-05 1995-06-28 日本レダリ−株式会社 （１ｒ）−１−メチルカルバペネム−３−カルボン酸誘導体
JPS6425780A (en) * 1987-04-28 1989-01-27 Sankyo Co 1-methylcarbapenem derivative
FI96863C (fi) * 1990-02-23 1996-09-10 Sankyo Co Menetelmä lääkeaineina käyttökelpoisten /2-(1-homopiperatsiinikarbonyyli)pyrrolidin-4-yylitio/-6-(1-hydroksietyyli)-1-karbapen-2-eemi-3-karboksylaattisuolojen valmistamiseksi
US5712267A (en) * 1991-06-04 1998-01-27 Sankyo Company,. Limited Carbapenem derivatives, their preparation and their use as antibiotics
WO1996008491A1 (fr) * 1994-09-16 1996-03-21 Banyu Pharmaceutical Co., Ltd. Nouveau derive de carbapeneme
CN1046729C (zh) 1994-09-16 1999-11-24 万有制药株式会社 新的碳代青霉烯衍生物
US5932048A (en) * 1995-04-06 1999-08-03 Komatsu Electronic Metals Co., Ltd. Method of fabricating direct-bonded semiconductor wafers
US20070234661A1 (en) * 2005-01-28 2007-10-11 Ed Vaes Multi piece curved moldings

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0082133A3 (en) * 1979-04-19 1983-07-20 Merck & Co. Inc. A process for preparing intermediates useful for preparing 2-substituted-6-substituted-1-carbadethiapen-2-em-3-carboxylic acids
PT73791B (en) * 1980-10-17 1983-10-14 Merck & Co Inc Process for preparing 2-carbamimidoyl-6-substituted-1- -carbadethiapen-2-em-3-carboxylic acids
EP0060612A1 (en) * 1981-02-04 1982-09-22 Beecham Group Plc Process for the preparation of azabicyclo(3.2.0)-hept-2-ene derivatives
ES8404184A1 (es) * 1981-08-03 1984-04-16 Merck & Co Inc Un procedimiento para la prepracion de nuevos derivados de acidos 2-carbamimidoil-1-,carbadestiapen-2-en-3-carboxilados.
JPS60178888A (ja) * 1984-02-22 1985-09-12 Sankyo Co Ltd ペネムまたはカルバペネム誘導体およびその製法

Also Published As

Publication number Publication date
CA1305709C (en) 1992-07-28
JPS6230781A (ja) 1987-02-09
DE3682225D1 (de) 1991-12-05
NZ215957A (en) 1988-04-29
EP0202048B1 (en) 1991-10-30
FI81577B (fi) 1990-07-31
FI861763A0 (fi) 1986-04-25
US4771046A (en) 1988-09-13
ATE69053T1 (de) 1991-11-15
KR920010076B1 (ko) 1992-11-13
PH22555A (en) 1988-10-17
IE58892B1 (en) 1993-12-01
JPH0710868B2 (ja) 1995-02-08
NO861630L (no) 1986-10-28
ZA863109B (en) 1986-12-30
AU5671086A (en) 1986-10-30
HU194882B (en) 1988-03-28
NO163452C (no) 1990-05-30
KR860008178A (ko) 1986-11-12
ES554474A0 (es) 1987-12-01
HUT40661A (en) 1987-01-28
NO163452B (no) 1990-02-19
AU583113B2 (en) 1989-04-20
ES8800952A1 (es) 1987-12-01
DK189686D0 (da) 1986-04-24
EP0202048A1 (en) 1986-11-20
FI861763A (fi) 1986-10-28
FI81577C (fi) 1990-11-12
IE861106L (en) 1986-10-27

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