DK1855102T3 - Fluorescens påvisningsapparat og en fluorescens påvisningsmetode - Google Patents

Fluorescens påvisningsapparat og en fluorescens påvisningsmetode

Info

Publication number
DK1855102T3
DK1855102T3 DK06713774.5T DK06713774T DK1855102T3 DK 1855102 T3 DK1855102 T3 DK 1855102T3 DK 06713774 T DK06713774 T DK 06713774T DK 1855102 T3 DK1855102 T3 DK 1855102T3
Authority
DK
Denmark
Prior art keywords
fluorescence detection
detection method
detection apparatus
fluorescence
detection
Prior art date
Application number
DK06713774.5T
Other languages
English (en)
Inventor
N Kimura
K Doi
T Yumii
T Yoshida
S Nakada
H Hayashi
K Hoshishima
Original Assignee
Mitsui Shipbuilding Eng
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP2005037399A external-priority patent/JP4384064B2/ja
Priority claimed from JP2005285084A external-priority patent/JP4540579B2/ja
Application filed by Mitsui Shipbuilding Eng filed Critical Mitsui Shipbuilding Eng
Application granted granted Critical
Publication of DK1855102T3 publication Critical patent/DK1855102T3/da

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/27Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection ; circuits for computing concentration
    • G01N21/274Calibration, base line adjustment, drift correction
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6408Fluorescence; Phosphorescence with measurement of decay time, time resolved fluorescence
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N2021/6417Spectrofluorimetric devices
    • G01N2021/6419Excitation at two or more wavelengths
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N2021/6417Spectrofluorimetric devices
    • G01N2021/6421Measuring at two or more wavelengths
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6439Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N2021/6482Sample cells, cuvettes

Landscapes

  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Optics & Photonics (AREA)
  • Engineering & Computer Science (AREA)
  • Mathematical Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
DK06713774.5T 2005-02-15 2006-02-15 Fluorescens påvisningsapparat og en fluorescens påvisningsmetode DK1855102T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2005037399A JP4384064B2 (ja) 2005-02-15 2005-02-15 強度変調したレーザ光による蛍光検出装置
JP2005285084A JP4540579B2 (ja) 2005-09-29 2005-09-29 蛍光強度算出方法及び蛍光強度算出装置
PCT/JP2006/302633 WO2006088047A1 (ja) 2005-02-15 2006-02-15 蛍光検出装置及び蛍光検出方法

Publications (1)

Publication Number Publication Date
DK1855102T3 true DK1855102T3 (da) 2012-01-02

Family

ID=36916451

Family Applications (1)

Application Number Title Priority Date Filing Date
DK06713774.5T DK1855102T3 (da) 2005-02-15 2006-02-15 Fluorescens påvisningsapparat og en fluorescens påvisningsmetode

Country Status (4)

Country Link
US (1) US7822558B2 (da)
EP (2) EP2369326B1 (da)
DK (1) DK1855102T3 (da)
WO (1) WO2006088047A1 (da)

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JP4365439B2 (ja) 2008-03-04 2009-11-18 三井造船株式会社 蛍光検出方法及び蛍光検出装置
CN102159937A (zh) * 2008-09-19 2011-08-17 三井造船株式会社 采用强度调制激光的荧光检测装置和荧光检测方法
CN102150035A (zh) * 2008-09-19 2011-08-10 三井造船株式会社 采用强度调制激光的荧光检测装置和荧光检测方法
US20110266462A1 (en) * 2009-01-09 2011-11-03 Mitsui Engineering & Shipbuilding Co., Ltd Fluorescence detecting device and fluorescence detecting method
EP2390655A1 (en) 2009-01-22 2011-11-30 Mitsui Engineering & Shipbuilding Co., Ltd. Fluorescence detecting device and fluorescence detecting method
JP4523674B1 (ja) * 2009-01-23 2010-08-11 三井造船株式会社 蛍光検出装置及び蛍光検出方法
JP4606518B2 (ja) * 2009-02-10 2011-01-05 三井造船株式会社 蛍光検出装置及び蛍光検出方法
JP4564566B2 (ja) * 2009-02-13 2010-10-20 三井造船株式会社 蛍光検出装置及び蛍光検出方法
JP4564567B2 (ja) 2009-02-13 2010-10-20 三井造船株式会社 蛍光検出装置及び蛍光検出方法
JP4620786B2 (ja) 2009-02-17 2011-01-26 三井造船株式会社 蛍光検出方法、蛍光検出装置及びプログラム
DE102009024943A1 (de) * 2009-06-10 2010-12-16 W.O.M. World Of Medicine Ag Bildgebungssystem und Verfahren zur fluoreszenz-optischen Visualisierung eines Objekts
CN102822665A (zh) * 2009-06-12 2012-12-12 三井造船株式会社 荧光检测装置和荧光检测方法
JP4818481B2 (ja) * 2010-01-06 2011-11-16 三井造船株式会社 蛍光検出装置および蛍光検出方法
KR20120103659A (ko) * 2010-01-15 2012-09-19 미쯔이 죠센 가부시키가이샤 형광 측정 장치 및 형광 측정 방법
EP2527819A1 (en) * 2010-01-21 2012-11-28 Mitsui Engineering & Shipbuilding Co., Ltd. Method for detection of fluorescence, process for production of fluorescent beads, and fluorescent beads
JP4818441B2 (ja) * 2010-01-25 2011-11-16 三井造船株式会社 蛍光測定装置及び蛍光測定方法
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JP5433517B2 (ja) * 2010-07-14 2014-03-05 株式会社日立ハイテクノロジーズ 解析装置及び解析方法
JP5494351B2 (ja) * 2010-08-24 2014-05-14 ソニー株式会社 蛍光強度補正方法、蛍光強度算出方法及び蛍光強度算出装置並びに蛍光強度補正プログラム
JP5937780B2 (ja) * 2010-11-11 2016-06-22 ソニー株式会社 蛍光スペクトル補正方法及び蛍光スペクトル測定装置
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CN102519923A (zh) * 2011-11-23 2012-06-27 北京金索坤技术开发有限公司 一种用于实现火焰法与氢化法联用的原子荧光光谱仪系统
US9632030B1 (en) 2012-11-05 2017-04-25 Arrowhead Center, Inc. Methods of measuring fluorescence lifetime using a flow cytometer
CN102967556B (zh) * 2012-12-06 2014-12-10 中国科学技术大学 一种基于数字微镜器件的微流控芯片加工与检测实验装置
US10031063B2 (en) * 2013-07-23 2018-07-24 Sony Corporation Particle analysis apparatus and method for optically detecting particles
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FI20165148A (fi) * 2016-02-25 2017-08-26 Arcdia Int Oy Ltd Kaksoisfotoniviritteistä fluoresenssia hyödyntävä bioaffiniteettimääritysmenetelmä
US11199490B2 (en) 2016-06-23 2021-12-14 Biocomp Instruments Inc. Flow cell and system for simultaneous measurement of absorbance and emission in a sample
US10197494B2 (en) * 2016-06-23 2019-02-05 Biocomp Instruments Inc. Flow cell and system for simultaneous measurement of absorbance and emission in a sample
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CN108051416A (zh) * 2017-12-12 2018-05-18 台州安诺凯生物科技有限公司 多项目上转换荧光检测方法及装置
WO2019181205A1 (ja) * 2018-03-19 2019-09-26 ソニー株式会社 情報処理装置、情報処理システム及び情報処理方法
CN109596565B (zh) * 2018-10-12 2021-05-11 上海禾赛科技股份有限公司 一种基于激光器阵列实现接收光强自稳定的装置及方法
CN109490176B (zh) * 2018-11-30 2019-11-22 苏州深析智能科技有限公司 流式细胞检测数据处理方法、装置及分型方法、装置
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Also Published As

Publication number Publication date
EP1855102B1 (en) 2011-09-07
EP2369326B1 (en) 2013-09-04
EP1855102A1 (en) 2007-11-14
US20090012721A1 (en) 2009-01-08
US7822558B2 (en) 2010-10-26
EP2369326A1 (en) 2011-09-28
EP1855102B8 (en) 2012-03-14
EP1855102A4 (en) 2010-06-09
WO2006088047A1 (ja) 2006-08-24

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