DK1814848T3 - 2,3,4-substitueret-cyclopentanoner som terapeutiske midler - Google Patents
2,3,4-substitueret-cyclopentanoner som terapeutiske midlerInfo
- Publication number
- DK1814848T3 DK1814848T3 DK05852061.0T DK05852061T DK1814848T3 DK 1814848 T3 DK1814848 T3 DK 1814848T3 DK 05852061 T DK05852061 T DK 05852061T DK 1814848 T3 DK1814848 T3 DK 1814848T3
- Authority
- DK
- Denmark
- Prior art keywords
- cyclopentanones
- substituted
- therapeutic agents
- disclosed
- prodrug
- Prior art date
Links
- 239000003814 drug Substances 0.000 title abstract 2
- 229940124597 therapeutic agent Drugs 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000000651 prodrug Substances 0.000 abstract 1
- 229940002612 prodrug Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/52—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0033—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing sulfur
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D333/56—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Ophthalmology & Optometry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Detergent Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/997,039 US7183324B2 (en) | 2004-11-23 | 2004-11-23 | 2,3,4-substituted cyclopentanones as therapeutic agents |
| PCT/US2005/042428 WO2006058063A1 (en) | 2004-11-23 | 2005-11-21 | 2,3,4-substituted-cyclopentanones as therapeutic agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1814848T3 true DK1814848T3 (da) | 2010-11-08 |
Family
ID=36087629
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK05852061.0T DK1814848T3 (da) | 2004-11-23 | 2005-11-21 | 2,3,4-substitueret-cyclopentanoner som terapeutiske midler |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7183324B2 (enExample) |
| EP (1) | EP1814848B9 (enExample) |
| JP (1) | JP5114205B2 (enExample) |
| AT (1) | ATE475643T1 (enExample) |
| AU (1) | AU2005309605B2 (enExample) |
| BR (1) | BRPI0518299A2 (enExample) |
| CA (1) | CA2588599A1 (enExample) |
| DE (1) | DE602005022613D1 (enExample) |
| DK (1) | DK1814848T3 (enExample) |
| ES (1) | ES2347808T3 (enExample) |
| WO (1) | WO2006058063A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050222094A1 (en) * | 2001-06-14 | 2005-10-06 | Burk Robert M | Treatment of inflammatory bowel disease |
| US7872045B2 (en) | 2001-06-14 | 2011-01-18 | Allergan, Inc. | Combination therapy for glaucoma treatment |
| US7799336B2 (en) | 2004-04-30 | 2010-09-21 | Allergan, Inc. | Hypotensive lipid-containing biodegradable intraocular implants and related methods |
| TWI386208B (zh) * | 2005-04-18 | 2013-02-21 | Allergan Inc | 治療性的經取代環戊酮 |
| US20070232660A1 (en) * | 2006-04-04 | 2007-10-04 | Allergan, Inc. | Therapeutic and delivery methods of prostaglandin ep4 agonists |
| MX2009012043A (es) | 2007-05-08 | 2010-02-18 | Nat Univ Corp Hamamatsu | Activador de celulas t citotoxicas que comprende agonista ep4. |
| US7781465B2 (en) * | 2007-08-21 | 2010-08-24 | Allergan, Inc. | Therapeutic oxazolidinones and thiazolidinones |
| US20110293549A1 (en) | 2009-02-03 | 2011-12-01 | Athena Cosmetics, Inc. | Composition, method and kit for enhancing hair |
| BR112012008959A2 (pt) | 2009-10-14 | 2019-09-24 | Gemmus Pharma Inc | tratamento de terapia de combinação para infecções virais |
| SG187861A1 (en) * | 2010-08-17 | 2013-03-28 | Allergan Inc | Ep2 or ep4 agonists for treating corneal haze |
| US20160184387A1 (en) | 2013-08-09 | 2016-06-30 | Dominique Charmot | Compounds and methods for inhibiting phosphate transport |
| HUE050902T2 (hu) | 2013-10-31 | 2021-01-28 | Allergan Inc | Prosztamidot tartalmazó intraokuláris implantátumok és azok alkalmazási módszerei |
| CN106928121B (zh) * | 2015-12-29 | 2020-05-12 | 暨南大学 | 3-取代-苯并五元杂环-2-羰基化合物的高效制备方法 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4166452A (en) | 1976-05-03 | 1979-09-04 | Generales Constantine D J Jr | Apparatus for testing human responses to stimuli |
| DE2715838A1 (de) | 1977-04-05 | 1978-10-19 | Schering Ag | Neue prostanderivate und verfahren zu ihrer herstellung |
| US4256108A (en) | 1977-04-07 | 1981-03-17 | Alza Corporation | Microporous-semipermeable laminated osmotic system |
| US4131738A (en) | 1977-07-05 | 1978-12-26 | The Upjohn Company | 6-Hydroxy-PGE1 compounds |
| US4265874A (en) | 1980-04-25 | 1981-05-05 | Alza Corporation | Method of delivering drug with aid of effervescent activity generated in environment of use |
| US6043275A (en) | 1998-04-16 | 2000-03-28 | Ono Pharmaceutical Co., Ltd. | 3,7-dithiaprostanoic acid derivative |
| WO2000015608A1 (fr) | 1998-09-14 | 2000-03-23 | Ono Pharmaceutical Co., Ltd. | Derives e de phenyl-prostaglandine a substitution-φ et medicaments les contenant comme ingredient actif |
| OA12533A (en) | 2000-11-27 | 2006-06-05 | Pfizer Prod Inc | Ep4 receptor selective agonists in the treatment of osteoporosis. |
| US6410591B1 (en) | 2001-05-08 | 2002-06-25 | Allergan Sales, Inc. | 3,7 or 3 and 7 thia or oxa prostanoic acid derivatives as agents for lowering intraocular pressure |
| US20030027853A1 (en) | 2001-06-14 | 2003-02-06 | Allergan Sales, Inc. | 3, 7or3 and 7 thia or oxa prostanoic acid derivatives as agents for lowering intraocular pressure |
| AU2002259210B2 (en) | 2001-06-14 | 2007-11-08 | Allergan, Inc. | 3, 7 or 3 and 7 thia or oxa prostanoic acid derivatives as agents for lowering intraocular pressure |
| US7101906B2 (en) * | 2004-11-16 | 2006-09-05 | Allergan, Inc. | 2,3,4-substituted cyclopentanones as therapeutic agents |
-
2004
- 2004-11-23 US US10/997,039 patent/US7183324B2/en not_active Expired - Lifetime
-
2005
- 2005-11-21 AU AU2005309605A patent/AU2005309605B2/en not_active Ceased
- 2005-11-21 EP EP05852061A patent/EP1814848B9/en not_active Expired - Lifetime
- 2005-11-21 AT AT05852061T patent/ATE475643T1/de not_active IP Right Cessation
- 2005-11-21 JP JP2007543434A patent/JP5114205B2/ja not_active Expired - Fee Related
- 2005-11-21 DE DE602005022613T patent/DE602005022613D1/de not_active Expired - Lifetime
- 2005-11-21 DK DK05852061.0T patent/DK1814848T3/da active
- 2005-11-21 BR BRPI0518299-9A patent/BRPI0518299A2/pt not_active Application Discontinuation
- 2005-11-21 ES ES05852061T patent/ES2347808T3/es not_active Expired - Lifetime
- 2005-11-21 CA CA002588599A patent/CA2588599A1/en not_active Abandoned
- 2005-11-21 WO PCT/US2005/042428 patent/WO2006058063A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| ATE475643T1 (de) | 2010-08-15 |
| WO2006058063A1 (en) | 2006-06-01 |
| JP5114205B2 (ja) | 2013-01-09 |
| CA2588599A1 (en) | 2006-06-01 |
| AU2005309605A1 (en) | 2006-06-01 |
| US20060111430A1 (en) | 2006-05-25 |
| AU2005309605B2 (en) | 2012-08-23 |
| EP1814848B1 (en) | 2010-07-28 |
| US7183324B2 (en) | 2007-02-27 |
| BRPI0518299A2 (pt) | 2008-11-11 |
| EP1814848B9 (en) | 2011-12-21 |
| ES2347808T9 (es) | 2011-06-13 |
| DE602005022613D1 (en) | 2010-09-09 |
| JP2008520737A (ja) | 2008-06-19 |
| EP1814848A1 (en) | 2007-08-08 |
| ES2347808T3 (es) | 2010-11-04 |
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