AU2005309605B2 - 2,3,4-substituted-cyclopentanones as therapeutic agents - Google Patents
2,3,4-substituted-cyclopentanones as therapeutic agents Download PDFInfo
- Publication number
- AU2005309605B2 AU2005309605B2 AU2005309605A AU2005309605A AU2005309605B2 AU 2005309605 B2 AU2005309605 B2 AU 2005309605B2 AU 2005309605 A AU2005309605 A AU 2005309605A AU 2005309605 A AU2005309605 A AU 2005309605A AU 2005309605 B2 AU2005309605 B2 AU 2005309605B2
- Authority
- AU
- Australia
- Prior art keywords
- oxo
- enyl
- acetic acid
- hydroxy
- propylsulfanyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 0 *C(CCc1cc(cccc2)c2[s]1)C#C Chemical compound *C(CCc1cc(cccc2)c2[s]1)C#C 0.000 description 1
- FQDVDYXKZIOYLV-UHFFFAOYSA-N C#CC(CCc1cc2ccccc2[s]1)O Chemical compound C#CC(CCc1cc2ccccc2[s]1)O FQDVDYXKZIOYLV-UHFFFAOYSA-N 0.000 description 1
- BMCVOLSOTFKLCB-UHFFFAOYSA-N C=Cc(cccc1)c1SO Chemical compound C=Cc(cccc1)c1SO BMCVOLSOTFKLCB-UHFFFAOYSA-N 0.000 description 1
- OBGQHRUBQYVMHQ-UHFFFAOYSA-N CNC(CCc1cc(cccc2)c2[s]1)=O Chemical compound CNC(CCc1cc(cccc2)c2[s]1)=O OBGQHRUBQYVMHQ-UHFFFAOYSA-N 0.000 description 1
- XZWVJNJOWOJHFI-VOTSOKGWSA-N COC(/C=C/c1cc2ccccc2[s]1)=O Chemical compound COC(/C=C/c1cc2ccccc2[s]1)=O XZWVJNJOWOJHFI-VOTSOKGWSA-N 0.000 description 1
- NRCZUNLXPCBOMG-UHFFFAOYSA-N COC(CCc1cc(cccc2)c2[s]1)=O Chemical compound COC(CCc1cc(cccc2)c2[s]1)=O NRCZUNLXPCBOMG-UHFFFAOYSA-N 0.000 description 1
- NXSVNPSWARVMAY-UHFFFAOYSA-N O=Cc1cc2ccccc2[s]1 Chemical compound O=Cc1cc2ccccc2[s]1 NXSVNPSWARVMAY-UHFFFAOYSA-N 0.000 description 1
- DYSJMQABFPKAQM-UHFFFAOYSA-N OC(c1cc(cccc2)c2[s]1)=O Chemical compound OC(c1cc(cccc2)c2[s]1)=O DYSJMQABFPKAQM-UHFFFAOYSA-N 0.000 description 1
- SUHKSQTXXZQEBH-UHFFFAOYSA-N OCc1cc(cccc2)c2[s]1 Chemical compound OCc1cc(cccc2)c2[s]1 SUHKSQTXXZQEBH-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/52—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0033—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing sulfur
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D333/56—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Ophthalmology & Optometry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Detergent Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/997,039 | 2004-11-23 | ||
| US10/997,039 US7183324B2 (en) | 2004-11-23 | 2004-11-23 | 2,3,4-substituted cyclopentanones as therapeutic agents |
| PCT/US2005/042428 WO2006058063A1 (en) | 2004-11-23 | 2005-11-21 | 2,3,4-substituted-cyclopentanones as therapeutic agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2005309605A1 AU2005309605A1 (en) | 2006-06-01 |
| AU2005309605B2 true AU2005309605B2 (en) | 2012-08-23 |
Family
ID=36087629
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2005309605A Ceased AU2005309605B2 (en) | 2004-11-23 | 2005-11-21 | 2,3,4-substituted-cyclopentanones as therapeutic agents |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7183324B2 (enExample) |
| EP (1) | EP1814848B9 (enExample) |
| JP (1) | JP5114205B2 (enExample) |
| AT (1) | ATE475643T1 (enExample) |
| AU (1) | AU2005309605B2 (enExample) |
| BR (1) | BRPI0518299A2 (enExample) |
| CA (1) | CA2588599A1 (enExample) |
| DE (1) | DE602005022613D1 (enExample) |
| DK (1) | DK1814848T3 (enExample) |
| ES (1) | ES2347808T3 (enExample) |
| WO (1) | WO2006058063A1 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050222094A1 (en) * | 2001-06-14 | 2005-10-06 | Burk Robert M | Treatment of inflammatory bowel disease |
| US7872045B2 (en) | 2001-06-14 | 2011-01-18 | Allergan, Inc. | Combination therapy for glaucoma treatment |
| US7799336B2 (en) | 2004-04-30 | 2010-09-21 | Allergan, Inc. | Hypotensive lipid-containing biodegradable intraocular implants and related methods |
| TWI386208B (zh) * | 2005-04-18 | 2013-02-21 | Allergan Inc | 治療性的經取代環戊酮 |
| US20070232660A1 (en) * | 2006-04-04 | 2007-10-04 | Allergan, Inc. | Therapeutic and delivery methods of prostaglandin ep4 agonists |
| CN101686985A (zh) | 2007-05-08 | 2010-03-31 | 国立大学法人浜松医科大学 | 含有ep4激动剂的细胞毒性t细胞的活化剂 |
| US7781465B2 (en) * | 2007-08-21 | 2010-08-24 | Allergan, Inc. | Therapeutic oxazolidinones and thiazolidinones |
| US20110293549A1 (en) | 2009-02-03 | 2011-12-01 | Athena Cosmetics, Inc. | Composition, method and kit for enhancing hair |
| US20120190637A1 (en) | 2009-10-14 | 2012-07-26 | Gemmus Pharma, Inc. | Combination therapy treatment for viral infections |
| CN103167875A (zh) * | 2010-08-17 | 2013-06-19 | 阿勒根公司 | 用于治疗角膜浑浊的ep2或ep4激动剂 |
| CA2920856C (en) | 2013-08-09 | 2026-03-03 | Ardelyx, Inc. | Ph modulating compounds for inhibiting gastrointestinal phosphate uptake |
| EP4046628A1 (en) | 2013-10-31 | 2022-08-24 | Allergan, Inc. | Prostamide-containing intraocular implants and methods of use thereof |
| CN106928121B (zh) * | 2015-12-29 | 2020-05-12 | 暨南大学 | 3-取代-苯并五元杂环-2-羰基化合物的高效制备方法 |
| TWI879060B (zh) * | 2022-09-16 | 2025-04-01 | 法商液態空氣喬治斯克勞帝方法研究開發股份有限公司 | 用於沈積含金屬膜之新穎的螯合和空間位阻配位基及其相應有機金屬錯合物 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6410591B1 (en) * | 2001-05-08 | 2002-06-25 | Allergan Sales, Inc. | 3,7 or 3 and 7 thia or oxa prostanoic acid derivatives as agents for lowering intraocular pressure |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4166452A (en) | 1976-05-03 | 1979-09-04 | Generales Constantine D J Jr | Apparatus for testing human responses to stimuli |
| DE2715838A1 (de) | 1977-04-05 | 1978-10-19 | Schering Ag | Neue prostanderivate und verfahren zu ihrer herstellung |
| US4256108A (en) | 1977-04-07 | 1981-03-17 | Alza Corporation | Microporous-semipermeable laminated osmotic system |
| US4131738A (en) | 1977-07-05 | 1978-12-26 | The Upjohn Company | 6-Hydroxy-PGE1 compounds |
| US4265874A (en) | 1980-04-25 | 1981-05-05 | Alza Corporation | Method of delivering drug with aid of effervescent activity generated in environment of use |
| US6043275A (en) | 1998-04-16 | 2000-03-28 | Ono Pharmaceutical Co., Ltd. | 3,7-dithiaprostanoic acid derivative |
| EP1114816A4 (en) | 1998-09-14 | 2002-09-04 | Ono Pharmaceutical Co | SUBSTITUTED PHENYL-PROSTAGLANDIN E DERIVATIVES- $ g (V) AND MEDICINAL PRODUCTS CONTAINING THEM AS ACTIVE INGREDIENT |
| EA200300379A1 (ru) | 2000-11-27 | 2003-08-28 | Пфайзер Продактс Инк. | Селективные агонисты рецептора ep4 в лечении остеопороза |
| US20030027853A1 (en) * | 2001-06-14 | 2003-02-06 | Allergan Sales, Inc. | 3, 7or3 and 7 thia or oxa prostanoic acid derivatives as agents for lowering intraocular pressure |
| AU2002259210B2 (en) | 2001-06-14 | 2007-11-08 | Allergan, Inc. | 3, 7 or 3 and 7 thia or oxa prostanoic acid derivatives as agents for lowering intraocular pressure |
| US7101906B2 (en) * | 2004-11-16 | 2006-09-05 | Allergan, Inc. | 2,3,4-substituted cyclopentanones as therapeutic agents |
-
2004
- 2004-11-23 US US10/997,039 patent/US7183324B2/en not_active Expired - Lifetime
-
2005
- 2005-11-21 WO PCT/US2005/042428 patent/WO2006058063A1/en not_active Ceased
- 2005-11-21 ES ES05852061T patent/ES2347808T3/es not_active Expired - Lifetime
- 2005-11-21 AU AU2005309605A patent/AU2005309605B2/en not_active Ceased
- 2005-11-21 JP JP2007543434A patent/JP5114205B2/ja not_active Expired - Fee Related
- 2005-11-21 DK DK05852061.0T patent/DK1814848T3/da active
- 2005-11-21 BR BRPI0518299-9A patent/BRPI0518299A2/pt not_active Application Discontinuation
- 2005-11-21 AT AT05852061T patent/ATE475643T1/de not_active IP Right Cessation
- 2005-11-21 CA CA002588599A patent/CA2588599A1/en not_active Abandoned
- 2005-11-21 EP EP05852061A patent/EP1814848B9/en not_active Expired - Lifetime
- 2005-11-21 DE DE602005022613T patent/DE602005022613D1/de not_active Expired - Lifetime
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6410591B1 (en) * | 2001-05-08 | 2002-06-25 | Allergan Sales, Inc. | 3,7 or 3 and 7 thia or oxa prostanoic acid derivatives as agents for lowering intraocular pressure |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1814848A1 (en) | 2007-08-08 |
| ES2347808T3 (es) | 2010-11-04 |
| EP1814848B1 (en) | 2010-07-28 |
| WO2006058063A1 (en) | 2006-06-01 |
| US7183324B2 (en) | 2007-02-27 |
| DE602005022613D1 (en) | 2010-09-09 |
| US20060111430A1 (en) | 2006-05-25 |
| ATE475643T1 (de) | 2010-08-15 |
| EP1814848B9 (en) | 2011-12-21 |
| JP2008520737A (ja) | 2008-06-19 |
| ES2347808T9 (es) | 2011-06-13 |
| BRPI0518299A2 (pt) | 2008-11-11 |
| AU2005309605A1 (en) | 2006-06-01 |
| DK1814848T3 (da) | 2010-11-08 |
| CA2588599A1 (en) | 2006-06-01 |
| JP5114205B2 (ja) | 2013-01-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FGA | Letters patent sealed or granted (standard patent) | ||
| MK14 | Patent ceased section 143(a) (annual fees not paid) or expired |