DK175947B1 - Sårheling - Google Patents
Sårheling Download PDFInfo
- Publication number
- DK175947B1 DK175947B1 DK198904122A DK412289A DK175947B1 DK 175947 B1 DK175947 B1 DK 175947B1 DK 198904122 A DK198904122 A DK 198904122A DK 412289 A DK412289 A DK 412289A DK 175947 B1 DK175947 B1 DK 175947B1
- Authority
- DK
- Denmark
- Prior art keywords
- pdgf
- growth factor
- purified
- tgf
- wounds
- Prior art date
Links
- 230000029663 wound healing Effects 0.000 title claims description 12
- 108010038512 Platelet-Derived Growth Factor Proteins 0.000 claims description 66
- 102000010780 Platelet-Derived Growth Factor Human genes 0.000 claims description 66
- 101800004564 Transforming growth factor alpha Proteins 0.000 claims description 26
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- 208000027418 Wounds and injury Diseases 0.000 claims description 22
- 239000000203 mixture Substances 0.000 claims description 21
- 102000004887 Transforming Growth Factor beta Human genes 0.000 claims description 9
- 108090001012 Transforming Growth Factor beta Proteins 0.000 claims description 9
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Classifications
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- A—HUMAN NECESSITIES
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- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/27—Growth hormone [GH], i.e. somatotropin
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/49—Platelet-derived growth factor [PDGF]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1841—Transforming growth factor [TGF]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
- B65D81/02—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents specially adapted to protect contents from mechanical damage
- B65D81/05—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents specially adapted to protect contents from mechanical damage maintaining contents at spaced relation from package walls, or from other contents
- B65D81/051—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents specially adapted to protect contents from mechanical damage maintaining contents at spaced relation from package walls, or from other contents using pillow-like elements filled with cushioning material, e.g. elastic foam, fabric
- B65D81/052—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents specially adapted to protect contents from mechanical damage maintaining contents at spaced relation from package walls, or from other contents using pillow-like elements filled with cushioning material, e.g. elastic foam, fabric filled with fluid, e.g. inflatable elements
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Endocrinology (AREA)
- Toxicology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Mechanical Engineering (AREA)
- Dermatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Packages (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13639987 | 1987-12-22 | ||
| US07/136,399 US4874746A (en) | 1987-12-22 | 1987-12-22 | Wound headling composition of TGF-alpha and PDGF |
| PCT/US1988/004557 WO1989005656A1 (en) | 1987-12-22 | 1988-12-20 | Wound healing |
| US8804557 | 1988-12-20 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK412289D0 DK412289D0 (da) | 1989-08-22 |
| DK412289A DK412289A (da) | 1989-10-19 |
| DK175947B1 true DK175947B1 (da) | 2005-08-08 |
Family
ID=22472686
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK198904122A DK175947B1 (da) | 1987-12-22 | 1989-08-22 | Sårheling |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US4874746A (ja) |
| EP (1) | EP0394349B1 (ja) |
| JP (2) | JPH03501973A (ja) |
| KR (1) | KR900700128A (ja) |
| CN (1) | CN1027136C (ja) |
| CA (1) | CA1322164C (ja) |
| DE (1) | DE3885300T2 (ja) |
| DK (1) | DK175947B1 (ja) |
| IE (1) | IE61283B1 (ja) |
| MX (1) | MX164966B (ja) |
| NZ (1) | NZ227429A (ja) |
| OA (1) | OA09129A (ja) |
| WO (1) | WO1989005656A1 (ja) |
| ZA (1) | ZA889594B (ja) |
Families Citing this family (74)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4889919A (en) * | 1986-08-13 | 1989-12-26 | Zymogenetics, Inc. | Biologically active PDGF derived A-chain homodimers |
| US5556620A (en) * | 1985-02-05 | 1996-09-17 | Cetus Oncology Corporation | Use of recombinant colony stimulating factor-1 to enhance wound healing |
| US5422105A (en) * | 1985-02-05 | 1995-06-06 | Cetus Oncology Corporation | Use of recombinant colony stimulating factor 1 |
| US5104650A (en) * | 1985-02-05 | 1992-04-14 | Cetus Corporation | Uses of recombinant colony stimulating factor-1 |
| US5474982A (en) * | 1986-08-13 | 1995-12-12 | Zymogenetics, Inc. | PDGF analogs and methods of use |
| US5226912A (en) | 1987-08-26 | 1993-07-13 | United States Surgical Corporation | Combined surgical needle-braided suture device |
| US5366081A (en) | 1987-08-26 | 1994-11-22 | United States Surgical Corporation | Packaged synthetic absorbable surgical elements |
| US5472702A (en) * | 1987-08-26 | 1995-12-05 | United States Surgical Corporation | Sterilization of growth factors |
| US5306289A (en) * | 1987-08-26 | 1994-04-26 | United States Surgical Corporation | Braided suture of improved characteristics |
| US5222978A (en) | 1987-08-26 | 1993-06-29 | United States Surgical Corporation | Packaged synthetic absorbable surgical elements |
| US5654267A (en) * | 1988-12-20 | 1997-08-05 | La Jolla Cancer Research Center | Cooperative combinations of ligands contained within a matrix |
| JPH04504216A (ja) * | 1989-03-31 | 1992-07-30 | ザ・リージエンツ・オブ・ザ・ユニバーシテイ・オブ・ミシガン | 細胞の特定部位点滴注入または細胞の部位特異的形質転換による疾患の治療及び該治療のためのキット |
| US7238673B2 (en) * | 1989-03-31 | 2007-07-03 | The Regents Of The University Of Michigan | Treatment of diseases by site-specific instillation of cells or site-specific transformation of cells and kits therefor |
| US5698531A (en) * | 1989-03-31 | 1997-12-16 | The Regents Of The University Of Michigan | Treatment of diseases by site-specific instillation of cells or site-specific transformation of cells and kits therefor |
| AU5816990A (en) * | 1989-05-12 | 1990-12-18 | State of Oregon, acting by and through The State Board of Education on behalf of The Oregon Health Sciences University, The | Keratinocyte autocrine factor |
| US5359831A (en) | 1989-08-01 | 1994-11-01 | United States Surgical Corporation | Molded suture retainer |
| US5246104A (en) * | 1989-08-01 | 1993-09-21 | United States Surgical Corporation | Molded suture retainer |
| US5035887A (en) * | 1989-09-07 | 1991-07-30 | Institute Of Moelcular Biology, Inc. | Wound healing composition of IL-1 and PDGF or IGF-1 |
| JPH04352800A (ja) * | 1990-10-26 | 1992-12-07 | Childrens Medical Center Corp:The | 平滑筋分裂促進因子 |
| US5955436A (en) * | 1990-11-20 | 1999-09-21 | Alcon Laboratories, Inc. | Use of platelet derived growth factor to enhance wound healing |
| US7196054B1 (en) | 1990-11-27 | 2007-03-27 | The American National Red Cross | Methods for treating wound tissue and forming a supplemented fibrin matrix |
| US6054122A (en) * | 1990-11-27 | 2000-04-25 | The American National Red Cross | Supplemented and unsupplemented tissue sealants, methods of their production and use |
| CA2097063C (en) * | 1990-11-27 | 2006-08-08 | Howard P. Greisler | Tissue sealant and growth factor containing compositions that promote accelerated wound healing |
| US6117425A (en) * | 1990-11-27 | 2000-09-12 | The American National Red Cross | Supplemented and unsupplemented tissue sealants, method of their production and use |
| US6559119B1 (en) | 1990-11-27 | 2003-05-06 | Loyola University Of Chicago | Method of preparing a tissue sealant-treated biomedical material |
| US6197325B1 (en) | 1990-11-27 | 2001-03-06 | The American National Red Cross | Supplemented and unsupplemented tissue sealants, methods of their production and use |
| US5360790A (en) * | 1990-12-11 | 1994-11-01 | The Regents Of The University Of Michigan | Method and formulations for the therapy of acute renal failure |
| CA2059245C (en) * | 1991-02-08 | 2004-07-06 | Michael P. Chesterfield | Method and apparatus for calendering and coating/filling sutures |
| US5149691A (en) * | 1991-03-12 | 1992-09-22 | Creative Biomolecules, Inc. | Issue repair and regeneration through the use of platelet derived growth factor (pdgf) in combination with dexamethasone |
| JPH06506939A (ja) * | 1991-04-12 | 1994-08-04 | クリエイティブ バイオモレキュルズ インコーポレイテッド | 血小板由来の成長因子に依る消化管潰瘍の治療方法 |
| AU3062392A (en) * | 1991-11-04 | 1993-06-07 | Novo Nordisk A/S | Pdgf gel formulation |
| US5302397A (en) * | 1991-11-19 | 1994-04-12 | Amsden Brian G | Polymer-based drug delivery system |
| JPH07508975A (ja) * | 1992-04-23 | 1995-10-05 | バーレックス ラボラトリーズ インコーポレイテッド | 生体接着性水性鉱油エマルション軟膏基剤，それからなる局所医薬組成物及び創傷治癒におけるその使用 |
| WO1993024627A1 (en) * | 1992-06-03 | 1993-12-09 | Case Western Reserve University | Bandage for continuous application of biologicals |
| FR2691911B1 (fr) * | 1992-06-05 | 1994-11-25 | Delmas Olivier | Dispositif permettant l'obtention d'un surnageant de thrombocytes activés, procédé mettant en Óoeuvre le dispositif et surnageant obtenu. |
| FR2696095B1 (fr) * | 1992-09-30 | 1994-11-25 | Inoteb | Colle biologique à base de protéines coagulables par la thrombine, enrichie en facteurs plaquettaires, sa préparation et son application. |
| US6040431A (en) | 1995-06-07 | 2000-03-21 | Stryker Corporation | Single chain analogs of the TGF-β superfamily (morphons) |
| EP0888086B1 (en) | 1996-02-15 | 2005-07-27 | Biosense Webster, Inc. | Excavation probe |
| US6443974B1 (en) * | 1996-07-28 | 2002-09-03 | Biosense, Inc. | Electromagnetic cardiac biostimulation |
| US6762336B1 (en) | 1998-01-19 | 2004-07-13 | The American National Red Cross | Hemostatic sandwich bandage |
| US20030129750A1 (en) * | 1998-02-05 | 2003-07-10 | Yitzhack Schwartz | Homing of donor cells to a target zone in tissue using active therapeutics or substances |
| ES2293473T3 (es) | 1998-02-05 | 2008-03-16 | Biosense Webster, Inc. | Administracion intracardiaca de farmaco. |
| US20030113303A1 (en) * | 1998-02-05 | 2003-06-19 | Yitzhack Schwartz | Homing of embryonic stem cells to a target zone in tissue using active therapeutics or substances |
| US7087577B2 (en) * | 1998-10-16 | 2006-08-08 | Zimmer Orthobiologies, Inc. | Method of promoting natural bypass |
| US6992066B2 (en) * | 1998-10-16 | 2006-01-31 | Zimmer Orthobiologics, Inc. | Povidone-containing carriers for polypeptide growth factors |
| US6663870B2 (en) * | 1998-12-07 | 2003-12-16 | Zymogenetics, Inc. | Methods for promoting growth of bone using zvegf3 |
| US20020099008A1 (en) | 1999-04-26 | 2002-07-25 | Daniel R. Twardzik | Method for stimulating hematopoiesis using tgf-alpha |
| CA2371241A1 (en) * | 1999-04-26 | 2000-11-02 | Stem Cell Pharmaceuticals, Inc. | Tgf-.alpha. polypeptides, functional fragments and methods of use therefor |
| US6468543B1 (en) * | 1999-05-03 | 2002-10-22 | Zymogenetics, Inc. | Methods for promoting growth of bone using ZVEGF4 |
| US6677307B2 (en) | 1999-08-19 | 2004-01-13 | Kaleidos Pharma, Inc. | TGF-α polypeptides, functional fragments and methods of use therefor |
| US20020193301A1 (en) * | 1999-08-19 | 2002-12-19 | Stem Cell Pharmaceuticals, Inc. | TGF-alpha polypeptides, functional fragments and methods of use therefor |
| US6815418B2 (en) * | 1999-08-19 | 2004-11-09 | Kaleidos Pharma, Inc. | TGF-α polypeptides, functional fragments and methods of use therefor |
| US20020077291A1 (en) * | 2000-09-22 | 2002-06-20 | Alan Upshall | Method of treatment of tumors using transforming growth factor-alpha |
| US6648911B1 (en) | 2000-11-20 | 2003-11-18 | Avantec Vascular Corporation | Method and device for the treatment of vulnerable tissue site |
| US7622562B2 (en) * | 2002-06-26 | 2009-11-24 | Zimmer Orthobiologics, Inc. | Rapid isolation of osteoinductive protein mixtures from mammalian bone tissue |
| US7241874B2 (en) * | 2002-06-26 | 2007-07-10 | Zimmer Ortho Biologics, Inc. | Rapid isolation of osteoinductive protein mixtures from mammalian bone tissue |
| US20060155234A1 (en) | 2002-09-10 | 2006-07-13 | American National Red Cross | Hemostatic dressing |
| US7473678B2 (en) | 2004-10-14 | 2009-01-06 | Biomimetic Therapeutics, Inc. | Platelet-derived growth factor compositions and methods of use thereof |
| US8114841B2 (en) | 2004-10-14 | 2012-02-14 | Biomimetic Therapeutics, Inc. | Maxillofacial bone augmentation using rhPDGF-BB and a biocompatible matrix |
| CA2641860C (en) | 2006-02-09 | 2015-07-14 | Biomimetic Therapeutics, Inc. | Compositions and methods for treating bone |
| ES2664229T3 (es) | 2006-06-30 | 2018-04-18 | Biomimetic Therapeutics, Llc | Composiciones y métodos de biomatriz-PDGF para el tratamiento de lesiones del manguito rotador |
| US9161967B2 (en) | 2006-06-30 | 2015-10-20 | Biomimetic Therapeutics, Llc | Compositions and methods for treating the vertebral column |
| CN101516301B (zh) * | 2006-08-04 | 2014-10-15 | Stb有限公司 | 用于处理受伤组织的固体敷料 |
| EP3181157B1 (en) | 2006-11-03 | 2019-08-14 | BioMimetic Therapeutics, LLC | Compositions and methods for arthrodetic procedures |
| WO2009020612A1 (en) * | 2007-08-06 | 2009-02-12 | Stb Lifesaving Technologies, Inc. | Methods and dressing for sealing internal injuries |
| ES2702809T3 (es) * | 2007-08-22 | 2019-03-05 | Noveome Biotherapeutics Inc | Composiciones novedosas de solución que contiene factor celular y su uso para tratar heridas |
| WO2009052221A2 (en) * | 2007-10-15 | 2009-04-23 | The Regents Of The University Of Colorado | Methods for extracting platelets and compositions obtained therefrom |
| CN105854074B (zh) | 2008-02-07 | 2019-10-15 | 生物模拟治疗有限责任公司 | 用于牵引成骨术的组合物和方法 |
| AU2009291828C1 (en) | 2008-09-09 | 2016-03-17 | Biomimetic Therapeutics, Llc | Platelet-derived growth factor compositions and methods for the treatment of tendon and ligament injuries |
| US8734854B2 (en) * | 2009-07-09 | 2014-05-27 | Orogen Biosciences Inc. | Process for removing growth factors from platelets |
| US8492335B2 (en) | 2010-02-22 | 2013-07-23 | Biomimetic Therapeutics, Llc | Platelet-derived growth factor compositions and methods for the treatment of tendinopathies |
| EP3206670A4 (en) | 2014-10-14 | 2018-06-20 | Samuel Lynch | Compositions for treating wounds |
| US20220177533A1 (en) | 2018-08-08 | 2022-06-09 | Sree Chitra Tirunal Institute For Medical Sciences And Technology | Recombinant TGF a for wound healing purposes, and the process thereof |
| CN110790822B (zh) * | 2019-11-21 | 2021-04-06 | 南开大学 | 可模拟血小板衍生因子生物活性的多肽衍生物、纳米纤维及其应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0105014B1 (en) * | 1982-09-24 | 1992-05-20 | THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce | Repair of tissue in animals |
| EP0154434B1 (en) * | 1984-02-17 | 1993-01-27 | Genentech, Inc. | Human transforming growth factor and precursor or fragment thereof, cells, dna, vectors and methods for their production, compositions and products containing them, and related antibodies and diagnostic methods |
| NZ226171A (en) * | 1987-09-18 | 1990-06-26 | Ethicon Inc | Gel formulation containing polypeptide growth factor |
-
1987
- 1987-12-22 US US07/136,399 patent/US4874746A/en not_active Expired - Lifetime
-
1988
- 1988-12-20 JP JP89501944A patent/JPH03501973A/ja not_active Expired - Lifetime
- 1988-12-20 JP JP1501944A patent/JPH0649657B2/ja not_active Expired - Lifetime
- 1988-12-20 WO PCT/US1988/004557 patent/WO1989005656A1/en active IP Right Grant
- 1988-12-20 DE DE89901681T patent/DE3885300T2/de not_active Expired - Lifetime
- 1988-12-20 KR KR1019890701555A patent/KR900700128A/ko not_active Application Discontinuation
- 1988-12-20 EP EP89901681A patent/EP0394349B1/en not_active Expired - Lifetime
- 1988-12-21 IE IE383388A patent/IE61283B1/en not_active IP Right Cessation
- 1988-12-21 NZ NZ227429A patent/NZ227429A/xx unknown
- 1988-12-21 CN CN88109273A patent/CN1027136C/zh not_active Expired - Lifetime
- 1988-12-21 CA CA000586562A patent/CA1322164C/en not_active Expired - Lifetime
- 1988-12-22 ZA ZA889594A patent/ZA889594B/xx unknown
- 1988-12-22 MX MX14307A patent/MX164966B/es unknown
-
1989
- 1989-08-22 OA OA59630A patent/OA09129A/xx unknown
- 1989-08-22 DK DK198904122A patent/DK175947B1/da not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CN1027136C (zh) | 1994-12-28 |
| CN1036332A (zh) | 1989-10-18 |
| US4874746A (en) | 1989-10-17 |
| DE3885300T2 (de) | 1994-05-05 |
| DE3885300D1 (de) | 1993-12-02 |
| IE883833L (en) | 1989-06-22 |
| ZA889594B (en) | 1989-09-27 |
| EP0394349A1 (en) | 1990-10-31 |
| DK412289D0 (da) | 1989-08-22 |
| DK412289A (da) | 1989-10-19 |
| JPH01502180A (ja) | 1989-08-03 |
| EP0394349A4 (en) | 1990-12-12 |
| MX164966B (es) | 1992-10-09 |
| NZ227429A (en) | 1991-01-29 |
| OA09129A (en) | 1991-10-31 |
| JPH0649657B2 (ja) | 1994-06-29 |
| KR900700128A (ko) | 1990-08-11 |
| WO1989005656A1 (en) | 1989-06-29 |
| JPH03501973A (ja) | 1991-05-09 |
| IE61283B1 (en) | 1994-10-19 |
| EP0394349B1 (en) | 1993-10-27 |
| CA1322164C (en) | 1993-09-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PUP | Patent expired |