CN1027136C - 伤口的愈合 - Google Patents
伤口的愈合 Download PDFInfo
- Publication number
- CN1027136C CN1027136C CN88109273A CN88109273A CN1027136C CN 1027136 C CN1027136 C CN 1027136C CN 88109273 A CN88109273 A CN 88109273A CN 88109273 A CN88109273 A CN 88109273A CN 1027136 C CN1027136 C CN 1027136C
- Authority
- CN
- China
- Prior art keywords
- pdgf
- tgf
- wound
- purification
- people
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
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- ZRKFYGHZFMAOKI-QMGMOQQFSA-N tgfbeta Chemical compound C([C@H](NC(=O)[C@H](C(C)C)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CCSC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N1[C@@H](CCC1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(O)=O)C1=CC=C(O)C=C1 ZRKFYGHZFMAOKI-QMGMOQQFSA-N 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/27—Growth hormone [GH], i.e. somatotropin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/49—Platelet-derived growth factor [PDGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1841—Transforming growth factor [TGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
- B65D81/02—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents specially adapted to protect contents from mechanical damage
- B65D81/05—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents specially adapted to protect contents from mechanical damage maintaining contents at spaced relation from package walls, or from other contents
- B65D81/051—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents specially adapted to protect contents from mechanical damage maintaining contents at spaced relation from package walls, or from other contents using pillow-like elements filled with cushioning material, e.g. elastic foam, fabric
- B65D81/052—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents specially adapted to protect contents from mechanical damage maintaining contents at spaced relation from package walls, or from other contents using pillow-like elements filled with cushioning material, e.g. elastic foam, fabric filled with fluid, e.g. inflatable elements
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Toxicology (AREA)
- Endocrinology (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Mechanical Engineering (AREA)
- Dermatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Packages (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US136,399 | 1987-12-22 | ||
| US07/136,399 US4874746A (en) | 1987-12-22 | 1987-12-22 | Wound headling composition of TGF-alpha and PDGF |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1036332A CN1036332A (zh) | 1989-10-18 |
| CN1027136C true CN1027136C (zh) | 1994-12-28 |
Family
ID=22472686
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN88109273A Expired - Lifetime CN1027136C (zh) | 1987-12-22 | 1988-12-21 | 伤口的愈合 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US4874746A (ja) |
| EP (1) | EP0394349B1 (ja) |
| JP (2) | JPH03501973A (ja) |
| KR (1) | KR900700128A (ja) |
| CN (1) | CN1027136C (ja) |
| CA (1) | CA1322164C (ja) |
| DE (1) | DE3885300T2 (ja) |
| DK (1) | DK175947B1 (ja) |
| IE (1) | IE61283B1 (ja) |
| MX (1) | MX164966B (ja) |
| NZ (1) | NZ227429A (ja) |
| OA (1) | OA09129A (ja) |
| WO (1) | WO1989005656A1 (ja) |
| ZA (1) | ZA889594B (ja) |
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| US9161967B2 (en) | 2006-06-30 | 2015-10-20 | Biomimetic Therapeutics, Llc | Compositions and methods for treating the vertebral column |
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| EP2185197B1 (en) * | 2007-08-22 | 2018-10-17 | Noveome Biotherapeutics, Inc. | Novel cellular factor- containing solution compositions and their use for treating wounds |
| WO2009052221A2 (en) * | 2007-10-15 | 2009-04-23 | The Regents Of The University Of Colorado | Methods for extracting platelets and compositions obtained therefrom |
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| NZ602861A (en) | 2008-09-09 | 2014-03-28 | Biomimetic Therapeutics Llc | Platelet-derived growth factor compositions and methods for the treatment of tendon and ligament injuries |
| US8734854B2 (en) * | 2009-07-09 | 2014-05-27 | Orogen Biosciences Inc. | Process for removing growth factors from platelets |
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| JP6871855B2 (ja) | 2014-10-14 | 2021-05-19 | サムエル リンチ， | 創傷を処置するための組成物 |
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| CN110790822B (zh) * | 2019-11-21 | 2021-04-06 | 南开大学 | 可模拟血小板衍生因子生物活性的多肽衍生物、纳米纤维及其应用 |
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| DE3382562D1 (de) * | 1982-09-24 | 1992-06-25 | Us Health | Wiederherstellung von gewebe bei tieren. |
| EP0154434B1 (en) * | 1984-02-17 | 1993-01-27 | Genentech, Inc. | Human transforming growth factor and precursor or fragment thereof, cells, dna, vectors and methods for their production, compositions and products containing them, and related antibodies and diagnostic methods |
| NZ226171A (en) * | 1987-09-18 | 1990-06-26 | Ethicon Inc | Gel formulation containing polypeptide growth factor |
-
1987
- 1987-12-22 US US07/136,399 patent/US4874746A/en not_active Expired - Lifetime
-
1988
- 1988-12-20 JP JP89501944A patent/JPH03501973A/ja not_active Expired - Lifetime
- 1988-12-20 DE DE89901681T patent/DE3885300T2/de not_active Expired - Lifetime
- 1988-12-20 WO PCT/US1988/004557 patent/WO1989005656A1/en active IP Right Grant
- 1988-12-20 JP JP1501944A patent/JPH0649657B2/ja not_active Expired - Lifetime
- 1988-12-20 EP EP89901681A patent/EP0394349B1/en not_active Expired - Lifetime
- 1988-12-20 KR KR1019890701555A patent/KR900700128A/ko not_active Application Discontinuation
- 1988-12-21 IE IE383388A patent/IE61283B1/en not_active IP Right Cessation
- 1988-12-21 NZ NZ227429A patent/NZ227429A/xx unknown
- 1988-12-21 CN CN88109273A patent/CN1027136C/zh not_active Expired - Lifetime
- 1988-12-21 CA CA000586562A patent/CA1322164C/en not_active Expired - Lifetime
- 1988-12-22 MX MX14307A patent/MX164966B/es unknown
- 1988-12-22 ZA ZA889594A patent/ZA889594B/xx unknown
-
1989
- 1989-08-22 OA OA59630A patent/OA09129A/xx unknown
- 1989-08-22 DK DK198904122A patent/DK175947B1/da not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| MX164966B (es) | 1992-10-09 |
| KR900700128A (ko) | 1990-08-11 |
| US4874746A (en) | 1989-10-17 |
| DK175947B1 (da) | 2005-08-08 |
| WO1989005656A1 (en) | 1989-06-29 |
| DK412289A (da) | 1989-10-19 |
| IE61283B1 (en) | 1994-10-19 |
| OA09129A (en) | 1991-10-31 |
| EP0394349A1 (en) | 1990-10-31 |
| IE883833L (en) | 1989-06-22 |
| DK412289D0 (da) | 1989-08-22 |
| NZ227429A (en) | 1991-01-29 |
| JPH03501973A (ja) | 1991-05-09 |
| EP0394349A4 (en) | 1990-12-12 |
| JPH0649657B2 (ja) | 1994-06-29 |
| ZA889594B (en) | 1989-09-27 |
| DE3885300T2 (de) | 1994-05-05 |
| EP0394349B1 (en) | 1993-10-27 |
| JPH01502180A (ja) | 1989-08-03 |
| DE3885300D1 (de) | 1993-12-02 |
| CN1036332A (zh) | 1989-10-18 |
| CA1322164C (en) | 1993-09-14 |
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| C15 | Extension of patent right duration from 15 to 20 years for appl. with date before 31.12.1992 and still valid on 11.12.2001 (patent law change 1993) | ||
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