DK175774B1 - Farmaceutisk præparat til transdermal systemisk administration af et farmakologisk aktivt middel, fremgangsmåde til fremstilling deraf samt anvendelse af ketotifen til fremstilling af et lægemiddel - Google Patents

Farmaceutisk præparat til transdermal systemisk administration af et farmakologisk aktivt middel, fremgangsmåde til fremstilling deraf samt anvendelse af ketotifen til fremstilling af et lægemiddel Download PDF

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Publication number
DK175774B1
DK175774B1 DK198505029A DK502985A DK175774B1 DK 175774 B1 DK175774 B1 DK 175774B1 DK 198505029 A DK198505029 A DK 198505029A DK 502985 A DK502985 A DK 502985A DK 175774 B1 DK175774 B1 DK 175774B1
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DK
Denmark
Prior art keywords
active agent
polymer
drug
ketotifen
pharmacologically active
Prior art date
Application number
DK198505029A
Other languages
Danish (da)
English (en)
Other versions
DK502985A (da
DK502985D0 (da
Inventor
Thomas Kissel
Hans-Rainer Hoffmann
Henriette Schrank
Original Assignee
Novartis Ag
Lohmann Therapie Syst Lts
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag, Lohmann Therapie Syst Lts filed Critical Novartis Ag
Priority to DK198505029A priority Critical patent/DK175774B1/da
Publication of DK502985A publication Critical patent/DK502985A/da
Publication of DK502985D0 publication Critical patent/DK502985D0/da
Priority to DK198703245A priority patent/DK175236B1/da
Priority to DK200401790A priority patent/DK175982B1/da
Priority to DK200401791A priority patent/DK175981B1/da
Application granted granted Critical
Publication of DK175774B1 publication Critical patent/DK175774B1/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/48—Ergoline derivatives, e.g. lysergic acid, ergotamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Steroid Compounds (AREA)
DK198505029A 1984-03-01 1985-10-31 Farmaceutisk præparat til transdermal systemisk administration af et farmakologisk aktivt middel, fremgangsmåde til fremstilling deraf samt anvendelse af ketotifen til fremstilling af et lægemiddel DK175774B1 (da)

Priority Applications (4)

Application Number Priority Date Filing Date Title
DK198505029A DK175774B1 (da) 1984-03-01 1985-10-31 Farmaceutisk præparat til transdermal systemisk administration af et farmakologisk aktivt middel, fremgangsmåde til fremstilling deraf samt anvendelse af ketotifen til fremstilling af et lægemiddel
DK198703245A DK175236B1 (da) 1984-03-01 1987-06-25 Farmaceutisk præparat
DK200401790A DK175982B1 (da) 1984-03-01 2004-11-18 Farmaceutisk præparat til transdermal systemisk administration af et farmakologisk aktivt middel, fremgangsmåde til fremstilling af et præparat og anvendelse af et polyacrylat til fremstilling af et lægemiddel
DK200401791A DK175981B1 (da) 1984-03-01 2004-11-18 Farmaceutisk præparat til transdermal systemisk administration af et farmakologisk aktivt middel, indeholdende tizanidin samt fremgangsmåde til fremstilling af præparatet

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
CH100884 1984-03-01
CH100884 1984-03-01
CH175384 1984-04-06
CH175384 1984-04-06
PCT/EP1985/000061 WO1985003878A1 (fr) 1984-03-01 1985-02-21 Compositions pharmaceutiques
EP8500061 1985-02-21
DK502985 1985-10-31
DK198505029A DK175774B1 (da) 1984-03-01 1985-10-31 Farmaceutisk præparat til transdermal systemisk administration af et farmakologisk aktivt middel, fremgangsmåde til fremstilling deraf samt anvendelse af ketotifen til fremstilling af et lægemiddel

Publications (3)

Publication Number Publication Date
DK502985A DK502985A (da) 1985-10-31
DK502985D0 DK502985D0 (da) 1985-10-31
DK175774B1 true DK175774B1 (da) 2005-02-14

Family

ID=25686369

Family Applications (2)

Application Number Title Priority Date Filing Date
DK198505029A DK175774B1 (da) 1984-03-01 1985-10-31 Farmaceutisk præparat til transdermal systemisk administration af et farmakologisk aktivt middel, fremgangsmåde til fremstilling deraf samt anvendelse af ketotifen til fremstilling af et lægemiddel
DK324687A DK164257C (da) 1984-03-01 1987-06-25 Transdermalt farmaceutisk praeparat

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK324687A DK164257C (da) 1984-03-01 1987-06-25 Transdermalt farmaceutisk praeparat

Country Status (18)

Country Link
EP (3) EP0315219B1 (fr)
JP (2) JPH0667835B2 (fr)
KR (1) KR920010392B1 (fr)
AT (3) ATE89750T1 (fr)
AU (2) AU578275B2 (fr)
CA (1) CA1257837A (fr)
DE (4) DE3587048T2 (fr)
DK (2) DK175774B1 (fr)
GR (1) GR850507B (fr)
HK (2) HK157896A (fr)
HU (1) HU197847B (fr)
IE (2) IE61754B1 (fr)
IL (1) IL74446A (fr)
MY (1) MY101919A (fr)
NZ (1) NZ211248A (fr)
PH (1) PH24392A (fr)
PT (1) PT80033B (fr)
WO (1) WO1985003878A1 (fr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU197847B (en) * 1984-03-01 1989-06-28 Sandoz Ag Process for producing therapeutical preparations suitable for transdermatic treating
US4713243A (en) * 1986-06-16 1987-12-15 Johnson & Johnson Products, Inc. Bioadhesive extruded film for intra-oral drug delivery and process
HU202753B (en) * 1986-06-21 1991-04-29 Sandoz Ag Process for producing retard pharmaceutical compositions containing cetotiphene
DE3643987A1 (de) * 1986-12-22 1988-06-23 Lohmann Therapie Syst Lts Basische, wirkstoffdurchlaessige haftklebende polymermasse, insbesondere zum einsatz mit basischen wirkstoffen, verfahren zu ihrer herstellung und ihre verwendung
DE3805744C2 (de) * 1987-03-04 1999-09-23 Novartis Ag Phenylcarbamate zur Hemmung der Acetylcholinesterase
DE3901551A1 (de) * 1989-01-20 1990-07-26 Lohmann Therapie Syst Lts Superfizielles therapeutisches system mit einem gehalt an einem antineoplastischen wirkstoff, insbesondere 5-fluoruracil
DE4020144A1 (de) * 1990-06-25 1992-01-09 Lohmann Therapie Syst Lts Pflaster mit hohem gehalt an weichmachenden inhaltsstoffen
DE4116912A1 (de) * 1991-05-18 1992-11-26 Schering Ag Mittel zur transdermalen applikation enthaltend ergolin-derivate
DE4310012A1 (de) * 1993-03-27 1994-09-29 Roehm Gmbh Dermales therapeutisches System aus einer schmelzfähigen Poly(meth)acrylat-Mischung
EP0808174B1 (fr) * 1995-02-10 2003-05-07 Christian Noe Medicament particulaire
US6165988A (en) * 1995-02-10 2000-12-26 Christian Noe Medicament in particulate form
US7150881B2 (en) 1997-06-26 2006-12-19 Mylan Technologies, Inc. Adhesive mixture for transdermal delivery of highly plasticizing drugs
DE19950066A1 (de) * 1999-10-16 2001-04-26 Lohmann Therapie Syst Lts Transdermales therapeutisches System mit einem Gehalt an Tulobuterol-hydrochlorid zur Verabreichung des Bronchodilatators Tulobuterol über die Haut
EP1170006B8 (fr) * 1999-12-14 2008-03-19 Teikoku Seiyaku Co., Ltd. Medicaments permettant de soulager l'hemicranie
DE10011447A1 (de) 2000-03-10 2001-09-20 Roehm Gmbh Dispersion mit nichtionischem Emulgator
DE10066158B4 (de) * 2000-08-24 2007-08-09 Neurobiotec Gmbh Verwendung eines transdermalen therapeutischen Systems zur Behandlung des Restless-Legs-Syndroms
US8512742B2 (en) 2009-05-01 2013-08-20 Hisamitsu Pharmaceutical Co., Inc. Transdermal preparation
KR101690765B1 (ko) * 2015-04-17 2016-12-28 동아제약 주식회사 항진균성 활성물질을 포함하는 경피 제제
WO2017037812A1 (fr) * 2015-08-29 2017-03-09 株式会社メドレックス Préparation pharmaceutique sous forme de timbre comprenant un accepteur d'acide
WO2018199018A1 (fr) * 2017-04-26 2018-11-01 ニプロ株式会社 Préparation absorbable par voie transdermique et son procédé de production

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2502951B1 (fr) * 1981-04-06 1985-12-06 Sandoz Sa Compositions pharmaceutiques topiques sous forme d'une micro-emulsion
CH653256A5 (en) * 1981-04-06 1985-12-31 Sandoz Ag Microemulsion for cutaneous use
DE3271647D1 (en) * 1981-07-08 1986-07-17 Key Pharma Polymeric diffusion matrix containing propranolol
CH653550A5 (de) * 1981-10-20 1986-01-15 Sandoz Ag Pharmazeutische zusammensetzung zur verzoegerten freigabe eines medikamentes im mundbereich.
JPS5925320A (ja) * 1982-08-02 1984-02-09 Watanabe Yakuhin Kogyo Kk 薬物投与用貼付剤
HU197847B (en) * 1984-03-01 1989-06-28 Sandoz Ag Process for producing therapeutical preparations suitable for transdermatic treating

Also Published As

Publication number Publication date
NZ211248A (en) 1988-10-28
IE61754B1 (en) 1994-11-30
HU197847B (en) 1989-06-28
ATE98876T1 (de) 1994-01-15
EP0315219B1 (fr) 1993-01-27
DE3587048T2 (de) 1993-06-03
JPH0748253A (ja) 1995-02-21
IL74446A (en) 1990-11-29
EP0315218A3 (fr) 1991-03-06
HK220096A (en) 1997-01-03
DK324687D0 (da) 1987-06-25
IE850493L (en) 1985-09-01
DE3587698T2 (de) 1994-04-28
JPS61501324A (ja) 1986-07-03
DK164257B (da) 1992-06-01
PT80033A (en) 1985-03-01
DE3587048D1 (de) 1993-03-11
AU578275B2 (en) 1988-10-20
CA1257837A (fr) 1989-07-25
HK157896A (en) 1996-08-30
EP0315218A2 (fr) 1989-05-10
DK324687A (da) 1987-06-25
DK502985A (da) 1985-10-31
DE3587794D1 (de) 1994-05-11
EP0315219A2 (fr) 1989-05-10
ATE89750T1 (de) 1993-06-15
DE3587698D1 (de) 1994-02-03
IE81316B1 (en) 2000-09-20
DK164257C (da) 1992-10-19
ATE103819T1 (de) 1994-04-15
PH24392A (en) 1990-06-13
DE3587358D1 (de) 1993-07-01
DK502985D0 (da) 1985-10-31
KR920010392B1 (ko) 1992-11-27
IE940083L (en) 1985-09-01
AU607496B2 (en) 1991-03-07
JPH0667835B2 (ja) 1994-08-31
EP0315219A3 (fr) 1991-03-06
MY101919A (en) 1992-02-15
WO1985003878A1 (fr) 1985-09-12
DE3587794T2 (de) 1994-08-04
AU4065085A (en) 1985-09-24
EP0315218B1 (fr) 1993-12-22
HUT41644A (en) 1987-05-28
KR850700218A (ko) 1985-12-26
EP0155229A3 (en) 1985-12-11
DE3587358T2 (de) 1993-11-04
IL74446A0 (en) 1985-05-31
EP0155229B1 (fr) 1993-05-26
GR850507B (fr) 1985-06-28
AU1662688A (en) 1988-10-20
PT80033B (pt) 1987-10-20
EP0155229A2 (fr) 1985-09-18
JP2540019B2 (ja) 1996-10-02

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