DK174978B1 - Anvendelse af human koagulationsfaktor XIII til fremstilling af et lægemiddel til hindring af intraventrikulær blødning hos for tidligt fødte børn - Google Patents

Anvendelse af human koagulationsfaktor XIII til fremstilling af et lægemiddel til hindring af intraventrikulær blødning hos for tidligt fødte børn Download PDF

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Publication number
DK174978B1
DK174978B1 DK198900838A DK83889A DK174978B1 DK 174978 B1 DK174978 B1 DK 174978B1 DK 198900838 A DK198900838 A DK 198900838A DK 83889 A DK83889 A DK 83889A DK 174978 B1 DK174978 B1 DK 174978B1
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DK
Denmark
Prior art keywords
factor xiii
coagulation factor
drug
precipitate
preparation
Prior art date
Application number
DK198900838A
Other languages
Danish (da)
English (en)
Other versions
DK83889D0 (da
DK83889A (da
Inventor
Minoru Uchida
Satoshi Tanaka
Akira Shirahata
Kenichiro Tsumura
Original Assignee
Hoechst Japan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Japan filed Critical Hoechst Japan
Publication of DK83889D0 publication Critical patent/DK83889D0/da
Publication of DK83889A publication Critical patent/DK83889A/da
Application granted granted Critical
Publication of DK174978B1 publication Critical patent/DK174978B1/da

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/16—Blood plasma; Blood serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/45—Transferases (2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK198900838A 1988-02-24 1989-02-23 Anvendelse af human koagulationsfaktor XIII til fremstilling af et lægemiddel til hindring af intraventrikulær blødning hos for tidligt fødte børn DK174978B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP63039646A JPH01216939A (ja) 1988-02-24 1988-02-24 末熟児頭蓋内出血阻止剤
JP3964688 1988-02-24

Publications (3)

Publication Number Publication Date
DK83889D0 DK83889D0 (da) 1989-02-23
DK83889A DK83889A (da) 1989-08-25
DK174978B1 true DK174978B1 (da) 2004-04-05

Family

ID=12558846

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198900838A DK174978B1 (da) 1988-02-24 1989-02-23 Anvendelse af human koagulationsfaktor XIII til fremstilling af et lægemiddel til hindring af intraventrikulær blødning hos for tidligt fødte børn

Country Status (12)

Country Link
US (1) US5114916A (de)
EP (1) EP0330049B1 (de)
JP (1) JPH01216939A (de)
KR (1) KR0137476B1 (de)
AT (1) ATE94070T1 (de)
AU (1) AU613154B2 (de)
CA (1) CA1332352C (de)
DE (1) DE68908913T2 (de)
DK (1) DK174978B1 (de)
ES (1) ES2059588T3 (de)
IE (1) IE63656B1 (de)
PT (1) PT89802B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5612456A (en) * 1988-11-14 1997-03-18 Zymogenetics, Inc. Factor XIII compositions
AU3423493A (en) * 1991-12-31 1993-07-28 Zymogenetics Inc. Methods and compositions for reducing blood loss
JP3550685B2 (ja) * 1992-04-21 2004-08-04 味の素株式会社 創傷治療剤
ATE184199T1 (de) * 1992-11-12 1999-09-15 Zymogenetics Inc Verwendung von lokal appliziertem faktor xiii zur verhinderung von blutungen
JPH07328108A (ja) * 1994-06-10 1995-12-19 Ajinomoto Co Inc 生体組織接着剤及び血液凝固剤
CA2338665C (en) 1998-08-06 2011-01-18 Mountain View Pharmaceuticals, Inc. Peg-urate oxidase conjugates and use thereof
JP2008510476A (ja) * 2004-08-27 2008-04-10 ノボ ノルディスク ヘルス ケア アクチェンゲゼルシャフト 生物学的材料からのｘｉｉｉ因子ポリペプチドの精製
EP1817339B1 (de) * 2004-11-23 2012-01-11 ZymoGenetics, Inc. Reinigung des rekombinanten menschlichen faktors xiii
ES2856881T3 (es) 2005-04-11 2021-09-28 Horizon Pharma Rheumatology Llc Formas variantes de urato oxidasa y su uso
TWI418564B (zh) * 2005-04-11 2013-12-11 Savient Pharmaceuticals Inc 利用陽離子界面活性劑之蛋白質純化
ES2532804T3 (es) * 2006-04-12 2015-03-31 Crealta Pharmaceuticals Llc Purificación de proteínas con tensioactivo catiónico
AU2010265964B2 (en) 2009-06-25 2014-09-18 Horizon Therapeutics Usa, Inc. Methods and kits for predicting infusion reaction risk and antibody-mediated loss of response by monitoring serum uric acid during PEGylated uricase therapy

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3717708A (en) * 1968-10-24 1973-02-20 Cutter Lab Blood coagulation complex
DE2063070C3 (de) * 1970-12-22 1975-07-24 Behringwerke Ag, 3550 Marburg Verfahren zur Herstellung eines Arzneimittels mit fibrinstabilisierender Wirkung
DE3622642A1 (de) * 1986-07-05 1988-01-14 Behringwerke Ag Einkomponenten-gewebekleber sowie verfahren zu seiner herstellung
DE3751269T2 (de) * 1986-09-19 1995-09-14 Univ Washington Expression des biologisch aktiven Faktors XIII.

Also Published As

Publication number Publication date
ES2059588T3 (es) 1994-11-16
US5114916A (en) 1992-05-19
DE68908913T2 (de) 1994-01-27
PT89802A (pt) 1989-10-04
IE63656B1 (en) 1995-05-31
CA1332352C (en) 1994-10-11
AU3024389A (en) 1989-08-24
IE890580L (en) 1989-08-24
JPH0378850B2 (de) 1991-12-17
DK83889D0 (da) 1989-02-23
JPH01216939A (ja) 1989-08-30
EP0330049B1 (de) 1993-09-08
DK83889A (da) 1989-08-25
DE68908913D1 (de) 1993-10-14
KR890012659A (ko) 1989-09-18
KR0137476B1 (ko) 1998-06-01
PT89802B (pt) 1994-04-29
ATE94070T1 (de) 1993-09-15
EP0330049A3 (de) 1991-01-30
EP0330049A2 (de) 1989-08-30
AU613154B2 (en) 1991-07-25

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