DK174201B1 - Substituerede 2-mercoptoimidazoler eller syreadditionssalte deraf samt fremgangsmåde til fremstilling af disse forbindelser - Google Patents

Substituerede 2-mercoptoimidazoler eller syreadditionssalte deraf samt fremgangsmåde til fremstilling af disse forbindelser Download PDF

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Publication number
DK174201B1
DK174201B1 DK198404713A DK471384A DK174201B1 DK 174201 B1 DK174201 B1 DK 174201B1 DK 198404713 A DK198404713 A DK 198404713A DK 471384 A DK471384 A DK 471384A DK 174201 B1 DK174201 B1 DK 174201B1
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Prior art keywords
formula
compounds
preparation
acid addition
substituted
Prior art date
Application number
DK198404713A
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Danish (da)
English (en)
Other versions
DK471384D0 (da
DK471384A (da
Inventor
Seppo S L Parhi
Original Assignee
Farmos Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmos Oy filed Critical Farmos Oy
Publication of DK471384D0 publication Critical patent/DK471384D0/da
Publication of DK471384A publication Critical patent/DK471384A/da
Application granted granted Critical
Publication of DK174201B1 publication Critical patent/DK174201B1/da

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/84Sulfur atoms

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Epoxy Resins (AREA)
  • Cephalosporin Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK198404713A 1983-10-18 1984-10-02 Substituerede 2-mercoptoimidazoler eller syreadditionssalte deraf samt fremgangsmåde til fremstilling af disse forbindelser DK174201B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI833794A FI833794A0 (fi) 1983-10-18 1983-10-18 Substituerade 2-merkapto-imidazoler
FI833794 1983-10-18

Publications (3)

Publication Number Publication Date
DK471384D0 DK471384D0 (da) 1984-10-02
DK471384A DK471384A (da) 1985-04-19
DK174201B1 true DK174201B1 (da) 2002-09-16

Family

ID=8517935

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198404713A DK174201B1 (da) 1983-10-18 1984-10-02 Substituerede 2-mercoptoimidazoler eller syreadditionssalte deraf samt fremgangsmåde til fremstilling af disse forbindelser

Country Status (18)

Country Link
US (1) US4584383A (ru)
EP (1) EP0146228B1 (ru)
JP (1) JPS60149568A (ru)
AT (1) ATE32064T1 (ru)
AU (1) AU566437B2 (ru)
DD (1) DD236730A1 (ru)
DE (1) DE3468869D1 (ru)
DK (1) DK174201B1 (ru)
ES (1) ES536186A0 (ru)
FI (1) FI833794A0 (ru)
HU (1) HU191960B (ru)
IE (1) IE57591B1 (ru)
IL (1) IL73255A (ru)
NO (1) NO159167C (ru)
NZ (1) NZ209896A (ru)
SU (1) SU1301313A3 (ru)
UA (1) UA5972A1 (ru)
ZA (1) ZA848112B (ru)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4634711A (en) * 1985-08-02 1987-01-06 Smithkline Beckman Corporation Pyridylalkyl imidazole-2-thiols
US5138069A (en) * 1986-07-11 1992-08-11 E. I. Du Pont De Nemours And Company Angiotensin II receptor blocking imidazoles
FI91754C (fi) * 1986-12-02 1994-08-10 Tanabe Seiyaku Co Analogiamenetelmä lääkeaineena käyttökelpoisen imidatsolijohdannaisen valmistamiseksi
US4882348A (en) * 1987-12-29 1989-11-21 Smithkline Beckman Corporation 2-(aminoalkylthio)imidazoles as dopamine-β-hydroxylase inhibitors
US5210079A (en) * 1988-01-07 1993-05-11 E. I. Du Pont De Nemours And Company Treatment of chronic renal failure with imidazole angiotensin-II receptor antagonists
CA1338238C (en) 1988-01-07 1996-04-09 David John Carini Angiotensin ii receptor blocking imidazoles and combinations thereof with diuretics and nsaids
US4880804A (en) * 1988-01-07 1989-11-14 E. I. Du Pont De Nemours And Company Angiotensin II receptor blocking benzimidazoles
US5354867A (en) * 1988-12-06 1994-10-11 E. I. Du Pont De Nemours And Company Angiotensin II receptor blocking imidazoles
CA2059000C (en) * 1989-06-30 1998-01-20 Robert John Ardecky Fused-ring aryl substituted imidazoles
US5073566A (en) * 1989-11-30 1991-12-17 Eli Lilly And Company Angiotensin ii antagonist 1,3-imidazoles and use thereas
US5332820A (en) * 1991-05-20 1994-07-26 E. I. Du Pont De Nemours And Company Dibenzobicyclo(2.2.2) octane angiotensin II antagonists
US5401851A (en) * 1992-06-03 1995-03-28 Eli Lilly And Company Angiotensin II antagonists
US5612360A (en) * 1992-06-03 1997-03-18 Eli Lilly And Company Angiotensin II antagonists
IT1295405B1 (it) 1997-09-30 1999-05-12 Merck Sharp & Dohme Italia S P Uso di un antagonista recettoriale di angiotensina ii per la preparazione di farmaci per aumentare il tasso di sopravvivenza di
KR100567183B1 (ko) * 1997-11-14 2006-06-13 론자 아게 포르밀이미다졸의제조방법
CN1372551A (zh) 1999-09-06 2002-10-02 株式会社Lgci 制备1-取代的5-羟甲基咪唑的方法
KR100388788B1 (ko) * 1999-09-06 2003-06-25 주식회사 엘지생명과학 1-치환된-5-하이드록시메틸 이미다졸의 신규 제조방법
US6620939B2 (en) * 2001-09-18 2003-09-16 General Electric Company Method for producing bisphenol catalysts and bisphenols
US7112702B2 (en) * 2002-12-12 2006-09-26 General Electric Company Process for the synthesis of bisphenol
FI116292B (fi) * 2003-01-08 2005-10-31 Juvantia Pharma Ltd Oy Menetelmä substituoitujen imidatsolijohdannaisten valmistamiseksi ja menetelmässä käytettäviä välituotteita
US7132575B2 (en) * 2003-07-01 2006-11-07 General Electric Company Process for the synthesis of bisphenol
FI20050391A0 (fi) * 2005-04-15 2005-04-15 Orion Corp Detomidiinihydrokloridin kiteytysmenetelmä
CN101747280B (zh) * 2008-11-28 2011-11-09 上海迪赛诺医药发展有限公司 制备地托咪定及其中间体的方法
US20210323929A1 (en) 2018-07-18 2021-10-21 Clexio Biosciences Ltd. Purified Detomidine, Process of Preparing and Methods of Use
EP3782989A1 (en) 2019-08-23 2021-02-24 Andreas Sachse Detomidine hydrochloride monohydrate

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2541924A (en) * 1948-09-17 1951-02-13 Lilly Co Eli Synthesis of substituted imidazoles
AU518569B2 (en) * 1979-08-07 1981-10-08 Farmos-Yhtyma Oy 4-benzyl- and 4-benzoyl imidazole derivatives
GB2092569B (en) * 1981-02-05 1984-09-19 Farmos Oy Substituted imidazole derivatives and their preparation and use

Also Published As

Publication number Publication date
NO159167B (no) 1988-08-29
SU1301313A3 (ru) 1987-03-30
NO159167C (no) 1988-12-07
IE842652L (en) 1985-04-18
UA5972A1 (ru) 1994-12-29
DK471384D0 (da) 1984-10-02
ATE32064T1 (de) 1988-02-15
ES8507507A1 (es) 1985-09-01
EP0146228A1 (en) 1985-06-26
ZA848112B (en) 1985-06-26
AU3426384A (en) 1985-04-26
ES536186A0 (es) 1985-09-01
HU191960B (en) 1987-04-28
NO844139L (no) 1985-04-19
US4584383A (en) 1986-04-22
JPS60149568A (ja) 1985-08-07
AU566437B2 (en) 1987-10-22
NZ209896A (en) 1987-02-20
DK471384A (da) 1985-04-19
DD236730A1 (de) 1986-06-18
DE3468869D1 (en) 1988-02-25
EP0146228B1 (en) 1988-01-20
HUT35649A (en) 1985-07-29
IE57591B1 (en) 1993-01-13
IL73255A (en) 1988-11-30
IL73255A0 (en) 1985-01-31
FI833794A0 (fi) 1983-10-18

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Date Code Title Description
B1 Patent granted (law 1993)
PUP Patent expired