DK1737820T3 - Asymmetrisk hydrogeneringsfremgangsmåde, som er nyttig til fremstilling af cycloalkanoindolderivater - Google Patents

Asymmetrisk hydrogeneringsfremgangsmåde, som er nyttig til fremstilling af cycloalkanoindolderivater

Info

Publication number
DK1737820T3
DK1737820T3 DK05732832T DK05732832T DK1737820T3 DK 1737820 T3 DK1737820 T3 DK 1737820T3 DK 05732832 T DK05732832 T DK 05732832T DK 05732832 T DK05732832 T DK 05732832T DK 1737820 T3 DK1737820 T3 DK 1737820T3
Authority
DK
Denmark
Prior art keywords
preparing
hydrogenation process
asymmetric hydrogenation
process useful
cycloalkanoindole
Prior art date
Application number
DK05732832T
Other languages
Danish (da)
English (en)
Inventor
David M Tellers
Guy R Humphrey
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Application granted granted Critical
Publication of DK1737820T3 publication Critical patent/DK1737820T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/80[b, c]- or [b, d]-condensed
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B53/00Asymmetric syntheses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/80[b, c]- or [b, d]-condensed
    • C07D209/94[b, c]- or [b, d]-condensed containing carbocyclic rings other than six-membered

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Indole Compounds (AREA)
  • Catalysts (AREA)
DK05732832T 2004-04-02 2005-03-29 Asymmetrisk hydrogeneringsfremgangsmåde, som er nyttig til fremstilling af cycloalkanoindolderivater DK1737820T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US55897204P 2004-04-02 2004-04-02
PCT/US2005/010501 WO2005097745A1 (en) 2004-04-02 2005-03-29 Asymmetric hydrogenation process useful for the preparation of cycloalkanoindole derivatives

Publications (1)

Publication Number Publication Date
DK1737820T3 true DK1737820T3 (da) 2008-04-28

Family

ID=34964828

Family Applications (1)

Application Number Title Priority Date Filing Date
DK05732832T DK1737820T3 (da) 2004-04-02 2005-03-29 Asymmetrisk hydrogeneringsfremgangsmåde, som er nyttig til fremstilling af cycloalkanoindolderivater

Country Status (19)

Country Link
US (1) US7576118B2 (zh)
EP (1) EP1737820B1 (zh)
JP (1) JP5239071B2 (zh)
CN (1) CN1942440B (zh)
AR (1) AR048459A1 (zh)
AT (1) ATE384046T1 (zh)
AU (1) AU2005230897B2 (zh)
BR (1) BRPI0509384A (zh)
CA (1) CA2561632A1 (zh)
CY (1) CY1107223T1 (zh)
DE (1) DE602005004393T2 (zh)
DK (1) DK1737820T3 (zh)
ES (1) ES2297695T3 (zh)
HR (1) HRP20080145T3 (zh)
PL (1) PL1737820T3 (zh)
PT (1) PT1737820E (zh)
SI (1) SI1737820T1 (zh)
TW (1) TWI344954B (zh)
WO (1) WO2005097745A1 (zh)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE030424T2 (en) 2008-07-23 2017-05-29 Arena Pharm Inc Substituted 1,2,3,4-tetrahydrocyclopenta [b] indol-3-ylacetic acid derivatives useful in the treatment of autoimmune and inflammatory disorders
BRPI0917923B1 (pt) 2008-08-27 2022-04-05 Arena Pharmaceuticals Inc Derivado de ácido tricíclico substituído, sua composição, seu uso e processo para preparar a referida composição
EP3378854B1 (en) 2010-01-27 2022-12-21 Arena Pharmaceuticals, Inc. Processes for the preparation of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid and salts thereof
JP2013521301A (ja) 2010-03-03 2013-06-10 アリーナ ファーマシューティカルズ, インコーポレイテッド S1p1受容体修飾物質およびその結晶形の調製のためのプロセス
CN102659664B (zh) * 2012-03-28 2015-01-21 中国计量学院 合成分离拉洛皮兰及其类似物的方法
MX2021011472A (es) 2015-01-06 2022-08-17 Arena Pharm Inc Metodos de condiciones de tratamiento relacionadas con el receptor s1p1.
KR102603199B1 (ko) 2015-06-22 2023-11-16 아레나 파마슈티칼스, 인크. S1p1 수용체-관련 장애에서의 사용을 위한 (r)-2-(7-(4-시클로펜틸-3-(트리플루오로메틸)벤질옥시)-1,2,3,4-테트라히드로시클로-펜타[b]인돌-3-일)아세트산 (화합물 1)의 결정성 l-아르기닌 염
CA3053416A1 (en) 2017-02-16 2018-08-23 Arena Pharmaceuticals, Inc. Compounds and methods for treatment of inflammatory bowel disease with extra-intestinal manifestations
WO2018151873A1 (en) 2017-02-16 2018-08-23 Arena Pharmaceuticals, Inc. Compounds and methods for treatment of primary biliary cholangitis
EP3847158A1 (en) 2018-09-06 2021-07-14 Arena Pharmaceuticals, Inc. Compounds useful in the treatment of autoimmune and inflammatory disorders

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3778857D1 (de) * 1986-11-14 1992-06-11 Takasago Perfumery Co Ltd Katalytische produktion von optisch aktiven carbonsaeuren.
AR038136A1 (es) * 2002-01-24 2004-12-29 Merck Frosst Canada Inc Cicloalcanindoles con sustitucion con fluor composiciones que contienen estos compuestos y metodos de tratamiento
EP1656141B1 (en) * 2003-08-07 2010-04-14 MERCK SHARP & DOHME LTD. Treatment for alzheimer s disease and related conditions

Also Published As

Publication number Publication date
DE602005004393D1 (de) 2008-03-06
JP2007532488A (ja) 2007-11-15
JP5239071B2 (ja) 2013-07-17
CN1942440A (zh) 2007-04-04
US20050222428A1 (en) 2005-10-06
DE602005004393T2 (de) 2009-01-08
CN1942440B (zh) 2011-09-14
CY1107223T1 (el) 2012-11-21
HRP20080145T3 (en) 2008-04-30
EP1737820B1 (en) 2008-01-16
TWI344954B (en) 2011-07-11
WO2005097745A1 (en) 2005-10-20
SI1737820T1 (sl) 2008-04-30
AU2005230897B2 (en) 2011-03-03
PL1737820T3 (pl) 2008-05-30
ES2297695T3 (es) 2008-05-01
AR048459A1 (es) 2006-04-26
BRPI0509384A (pt) 2007-09-18
ATE384046T1 (de) 2008-02-15
US7576118B2 (en) 2009-08-18
TW200606145A (en) 2006-02-16
PT1737820E (pt) 2008-03-17
AU2005230897A1 (en) 2005-10-20
EP1737820A1 (en) 2007-01-03
CA2561632A1 (en) 2005-10-20

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