DK173590D0 - Rekombinante terapeutiske lipaser - Google Patents

Rekombinante terapeutiske lipaser

Info

Publication number
DK173590D0
DK173590D0 DK173590A DK173590A DK173590D0 DK 173590 D0 DK173590 D0 DK 173590D0 DK 173590 A DK173590 A DK 173590A DK 173590 A DK173590 A DK 173590A DK 173590 D0 DK173590 D0 DK 173590D0
Authority
DK
Denmark
Prior art keywords
lipases
recombinant therapeutic
lipase
prophylaxis
mammals
Prior art date
Application number
DK173590A
Other languages
Danish (da)
English (en)
Inventor
Birgitte Huge-Jensen
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DK137990A external-priority patent/DK137990D0/da
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Priority to DK173590A priority Critical patent/DK173590D0/da
Publication of DK173590D0 publication Critical patent/DK173590D0/da
Priority to JP03510710A priority patent/JP3072853B2/ja
Priority to EP91910966A priority patent/EP0600868B1/fr
Priority to DE69131106T priority patent/DE69131106T2/de
Priority to AT91910966T priority patent/ATE178492T1/de
Priority to PCT/DK1991/000149 priority patent/WO1991018623A1/fr
Priority to AU80964/91A priority patent/AU645583B2/en
Priority to CA002084184A priority patent/CA2084184A1/fr
Priority to FI925530A priority patent/FI925530A/fi
Priority to US08/318,036 priority patent/US5614189A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18Carboxylic ester hydrolases (3.1.1)
    • C12N9/20Triglyceride splitting, e.g. by means of lipase
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
DK173590A 1990-06-06 1990-07-19 Rekombinante terapeutiske lipaser DK173590D0 (da)

Priority Applications (10)

Application Number Priority Date Filing Date Title
DK173590A DK173590D0 (da) 1990-06-06 1990-07-19 Rekombinante terapeutiske lipaser
CA002084184A CA2084184A1 (fr) 1990-06-06 1991-06-04 Lipases produites par recombinaison pour traitement therapeutique
AU80964/91A AU645583B2 (en) 1990-06-06 1991-06-04 Recombinantly produced lipases for therapeutical treatment
DE69131106T DE69131106T2 (de) 1990-06-06 1991-06-04 Gentechnologisch hergestellte lipasen für die therapeutische behandlung
EP91910966A EP0600868B1 (fr) 1990-06-06 1991-06-04 Lipases produites par procede recombinant et s'adressant au traitement therapeutique
JP03510710A JP3072853B2 (ja) 1990-06-06 1991-06-04 治療用に、組換方法で生産されたリパーゼ
AT91910966T ATE178492T1 (de) 1990-06-06 1991-06-04 Gentechnologisch hergestellte lipasen für die therapeutische behandlung
PCT/DK1991/000149 WO1991018623A1 (fr) 1990-06-06 1991-06-04 Lipases produites par procede recombinant et s'adressant au traitement therapeutique
FI925530A FI925530A (fi) 1990-06-06 1992-12-04 Rekombinantiskt framstaellda lipaser foer terapeutiskt bruk
US08/318,036 US5614189A (en) 1990-06-06 1994-10-04 Recombinantly produced lipases for therapeutical treatment

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK137990A DK137990D0 (da) 1990-06-06 1990-06-06 Rekombinante terapeutiske lipaser
DK173590A DK173590D0 (da) 1990-06-06 1990-07-19 Rekombinante terapeutiske lipaser

Publications (1)

Publication Number Publication Date
DK173590D0 true DK173590D0 (da) 1990-07-19

Family

ID=26065679

Family Applications (1)

Application Number Title Priority Date Filing Date
DK173590A DK173590D0 (da) 1990-06-06 1990-07-19 Rekombinante terapeutiske lipaser

Country Status (10)

Country Link
US (1) US5614189A (fr)
EP (1) EP0600868B1 (fr)
JP (1) JP3072853B2 (fr)
AT (1) ATE178492T1 (fr)
AU (1) AU645583B2 (fr)
CA (1) CA2084184A1 (fr)
DE (1) DE69131106T2 (fr)
DK (1) DK173590D0 (fr)
FI (1) FI925530A (fr)
WO (1) WO1991018623A1 (fr)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6140475A (en) * 1997-04-11 2000-10-31 Altus Biologics Inc. Controlled dissolution crosslinked protein crystals
US6541606B2 (en) 1997-12-31 2003-04-01 Altus Biologics Inc. Stabilized protein crystals formulations containing them and methods of making them
US20010046493A1 (en) * 2000-02-24 2001-11-29 Alex Margolin Lipase-containing composition and methods of use thereof
PT1729797E (pt) 2004-03-22 2008-12-17 Solvay Pharm Gmbh Composições farmacêuticas orais de produtos contendo lipase, em particular de pancreatina, contendo tensioactivos
BRPI0510817A (pt) * 2004-05-24 2007-11-20 Novozymes As protease, uso de uma protease, composição farmacêutica, e, método para o tratamento de uma doença
PL2198880T3 (pl) 2004-10-14 2017-04-28 Eli Lilly And Co. Kompozycje zawierające lipazę, proteazę i amylazę do leczenia niewydolności trzustki
BRPI0611936A2 (pt) * 2005-06-24 2011-02-22 Solvay Pharm Gmbh protease, uso de uma protease, composição farmacêutica, e, método para o tratamento de doença
CN101208429A (zh) * 2005-06-24 2008-06-25 诺维信公司 用于药物用途的脂肪酶
MX2007015471A (es) 2005-06-24 2008-04-04 Novozymes As Amilasas para uso farmaceutico.
BRPI0614914A2 (pt) * 2005-07-29 2011-04-19 Solvay Pharm Gmbh processos para a fabricação de pó de pancreatina esterilizada
US11266607B2 (en) 2005-08-15 2022-03-08 AbbVie Pharmaceuticals GmbH Process for the manufacture and use of pancreatin micropellet cores
US9198871B2 (en) 2005-08-15 2015-12-01 Abbott Products Gmbh Delayed release pancreatin compositions
US20100196344A1 (en) * 2005-10-14 2010-08-05 Cystic Fibrosis Foundation Therapeutics, Inc. Compositions and methods for treating pancreatic insufficiency
US8071089B2 (en) 2005-11-01 2011-12-06 Bio-Cat, Inc. Composition with a fungal (yeast) lipase and method for treating lipid malabsorption in cystic fibrosis as well as people suffering from pancreatic lipase insufficiency
US20070104805A1 (en) * 2005-11-01 2007-05-10 Udell Ronald G Compositions of Hoodia Gordonii and Pinolenic Acid Derivatives
US10072256B2 (en) 2006-05-22 2018-09-11 Abbott Products Gmbh Process for separating and determining the viral load in a pancreatin sample
CA2670643C (fr) 2006-12-21 2017-04-25 Novozymes A/S Variantes lipasiques pour une utilisation pharmaceutique
US20090130063A1 (en) * 2007-11-15 2009-05-21 Solvay Pharmaceuticals Gmbh Process for separating and determining the viral load in a pancreatin sample
RU2010127329A (ru) * 2007-12-04 2012-01-10 Новозимс А/С (Dk) Варианты протеаз для фармацевтического применения
BRPI0906439A2 (pt) * 2008-01-03 2018-12-04 Abbott Products Gmbh composições farmacêuticas que compreendem grânulos de lipase microbiana purificada e métodos para a prevenção ou tratamento de distúrbios digestivos
JP5970189B2 (ja) * 2009-01-29 2016-08-17 ノルドマルク・アルツナイミッテル・ゲゼルシヤフト・ミト・ベシュレンクテル・ハフツング・ウント・コンパニー・コマンデイトゲゼルシヤフト 医薬調製物
WO2011000924A1 (fr) 2009-07-03 2011-01-06 Abbott Products Gmbh Amylase séchée par pulvérisation, préparations pharmaceutiques la comprenant et son utilisation
US8268305B1 (en) 2011-09-23 2012-09-18 Bio-Cat, Inc. Method and compositions to reduce serum levels of triacylglycerides in human beings using a fungal lipase
CN105392496A (zh) * 2013-07-22 2016-03-09 阿普塔利斯制药有限公司 高效的胰酶药物组合物
JP2014193909A (ja) * 2014-06-04 2014-10-09 Nordmark Arzneimittel Gmbh & Co Kg 医薬調製物
GB201501081D0 (en) 2015-01-22 2015-03-11 Cilian Ag Use of enzymes with a wide pH activity range as medicaments for promoting digestion
WO2016126970A1 (fr) 2015-02-04 2016-08-11 Abbvie Inc. Compositions pharmaceutiques et méthodes d'utilisation de celles-ci pour traiter une insuffisance liée aux enzymes pancréatiques
DE102015114857A1 (de) * 2015-09-04 2017-03-09 Nordmark Arzneimittel Gmbh & Co. Kg Getränk, enthaltend eine pharmazeutische Zusammensetzung

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8421210D0 (en) * 1984-08-21 1984-09-26 Celltech Ltd Polypeptide and polypeptide composition
US4659667A (en) * 1985-02-26 1987-04-21 Miles Laboratories, Inc. Process to recover crystalline enzymes and crystalline enzymes produced thereby
US5108457A (en) * 1986-11-19 1992-04-28 The Clorox Company Enzymatic peracid bleaching system with modified enzyme
ATE125865T1 (de) * 1987-08-28 1995-08-15 Novo Nordisk As Rekombinante humicola-lipase und verfahren zur herstellung von rekombinanten humicola-lipasen.
JPH05502584A (ja) * 1989-12-21 1993-05-13 ノボ ノルディスク アクティーゼルスカブ 酵素含有調製品及び該調製品を含有する洗剤

Also Published As

Publication number Publication date
WO1991018623A1 (fr) 1991-12-12
EP0600868B1 (fr) 1999-04-07
AU8096491A (en) 1991-12-31
JPH06501147A (ja) 1994-02-10
DE69131106T2 (de) 1999-11-18
EP0600868A1 (fr) 1994-06-15
ATE178492T1 (de) 1999-04-15
CA2084184A1 (fr) 1991-12-07
US5614189A (en) 1997-03-25
FI925530A0 (fi) 1992-12-04
JP3072853B2 (ja) 2000-08-07
FI925530A (fi) 1992-12-04
DE69131106D1 (de) 1999-05-12
AU645583B2 (en) 1994-01-20

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Legal Events

Date Code Title Description
AHS Application shelved for other reasons than non-payment
B1 Patent granted (law 1993)
PUP Patent expired