FI925530A0 - Rekombinantiskt framstaellda lipaser foer terapeutiskt bruk - Google Patents

Rekombinantiskt framstaellda lipaser foer terapeutiskt bruk

Info

Publication number
FI925530A0
FI925530A0 FI925530A FI925530A FI925530A0 FI 925530 A0 FI925530 A0 FI 925530A0 FI 925530 A FI925530 A FI 925530A FI 925530 A FI925530 A FI 925530A FI 925530 A0 FI925530 A0 FI 925530A0
Authority
FI
Finland
Prior art keywords
lipaser
framstaellda
bruk
recombinant
therapeutic
Prior art date
Application number
FI925530A
Other languages
English (en)
Finnish (fi)
Other versions
FI925530A (fi
Inventor
Birgitte Huge-Jensen
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DK137990A external-priority patent/DK137990D0/da
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of FI925530A0 publication Critical patent/FI925530A0/fi
Publication of FI925530A publication Critical patent/FI925530A/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • C12N9/20—Triglyceride splitting, e.g. by means of lipase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
FI925530A 1990-06-06 1992-12-04 Rekombinantiskt framstaellda lipaser foer terapeutiskt bruk FI925530A (fi)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DK137990A DK137990D0 (da) 1990-06-06 1990-06-06 Rekombinante terapeutiske lipaser
DK173590A DK173590D0 (da) 1990-06-06 1990-07-19 Rekombinante terapeutiske lipaser
PCT/DK1991/000149 WO1991018623A1 (fr) 1990-06-06 1991-06-04 Lipases produites par procede recombinant et s'adressant au traitement therapeutique

Publications (2)

Publication Number Publication Date
FI925530A0 true FI925530A0 (fi) 1992-12-04
FI925530A FI925530A (fi) 1992-12-04

Family

ID=26065679

Family Applications (1)

Application Number Title Priority Date Filing Date
FI925530A FI925530A (fi) 1990-06-06 1992-12-04 Rekombinantiskt framstaellda lipaser foer terapeutiskt bruk

Country Status (10)

Country Link
US (1) US5614189A (fr)
EP (1) EP0600868B1 (fr)
JP (1) JP3072853B2 (fr)
AT (1) ATE178492T1 (fr)
AU (1) AU645583B2 (fr)
CA (1) CA2084184A1 (fr)
DE (1) DE69131106T2 (fr)
DK (1) DK173590D0 (fr)
FI (1) FI925530A (fr)
WO (1) WO1991018623A1 (fr)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6140475A (en) * 1997-04-11 2000-10-31 Altus Biologics Inc. Controlled dissolution crosslinked protein crystals
US6541606B2 (en) 1997-12-31 2003-04-01 Altus Biologics Inc. Stabilized protein crystals formulations containing them and methods of making them
US20010046493A1 (en) * 2000-02-24 2001-11-29 Alex Margolin Lipase-containing composition and methods of use thereof
PT1729797E (pt) 2004-03-22 2008-12-17 Solvay Pharm Gmbh Composições farmacêuticas orais de produtos contendo lipase, em particular de pancreatina, contendo tensioactivos
JP2008500055A (ja) * 2004-05-24 2008-01-10 ノボザイムス アクティーゼルスカブ 医薬用途のための酵素
CN101068565B (zh) 2004-10-14 2010-11-17 胞囊纤维化基础治疗公司 治疗胰腺功能不全的包含脂酶、蛋白酶和淀粉酶的组合物
US8017351B2 (en) 2005-06-24 2011-09-13 Novozymes A/S Amylases for pharmaceutical use
EP1896577A2 (fr) * 2005-06-24 2008-03-12 Novozymes A/S Lipases à usage pharmaceutique
EP1896058A2 (fr) * 2005-06-24 2008-03-12 Novozymes A/S Protéases à usage pharmaceutique
AU2006274835B2 (en) 2005-07-29 2012-05-24 Abbott Laboratories Gmbh Processes for the manufacture of sterilized pancreatin powder
US11266607B2 (en) 2005-08-15 2022-03-08 AbbVie Pharmaceuticals GmbH Process for the manufacture and use of pancreatin micropellet cores
US9198871B2 (en) 2005-08-15 2015-12-01 Abbott Products Gmbh Delayed release pancreatin compositions
US20100196344A1 (en) * 2005-10-14 2010-08-05 Cystic Fibrosis Foundation Therapeutics, Inc. Compositions and methods for treating pancreatic insufficiency
US20070104805A1 (en) * 2005-11-01 2007-05-10 Udell Ronald G Compositions of Hoodia Gordonii and Pinolenic Acid Derivatives
WO2007053619A2 (fr) 2005-11-01 2007-05-10 Bio-Cat, Inc. Composition contenant une lipase fongique (levure), et methode permettant de traiter la malabsorption lipidique liee a la mucoviscidose et l'insuffisance pancreatique chez des sujets concernes
US10072256B2 (en) 2006-05-22 2018-09-11 Abbott Products Gmbh Process for separating and determining the viral load in a pancreatin sample
BRPI0721103A2 (pt) 2006-12-21 2014-03-04 Novozymes As Lipase, método de determinação do desempenho da digestão in vitro de uma lipase em comparação com uma lipase de referência, uso de uma lipase ou de uma mistura de lipases, composição farmacêutica, e, método para o tratamento de doença
US20090130063A1 (en) * 2007-11-15 2009-05-21 Solvay Pharmaceuticals Gmbh Process for separating and determining the viral load in a pancreatin sample
CN101889084A (zh) * 2007-12-04 2010-11-17 诺维信公司 供药学应用的蛋白酶变体
KR20100101106A (ko) * 2008-01-03 2010-09-16 애보트 프러덕츠 게엠베하 정제 미생물 리파제 과립들을 포함하는 약학 조성물 및 소화 장애들의 예방 또는 치료방법
BRPI0922653B8 (pt) 2009-01-29 2021-05-25 Nordmark Arzneimittel Gmbh & Co Kg uso de uma lipase bacteriana do tipo pseudomonas em solução aquosa
WO2011000924A1 (fr) 2009-07-03 2011-01-06 Abbott Products Gmbh Amylase séchée par pulvérisation, préparations pharmaceutiques la comprenant et son utilisation
US8268305B1 (en) 2011-09-23 2012-09-18 Bio-Cat, Inc. Method and compositions to reduce serum levels of triacylglycerides in human beings using a fungal lipase
MX2016000794A (es) * 2013-07-22 2016-12-02 Allergan Pharmaceuticals Int Ltd Composiciones farmaceuticas de pancreatina de potencia alta.
JP2014193909A (ja) * 2014-06-04 2014-10-09 Nordmark Arzneimittel Gmbh & Co Kg 医薬調製物
GB201501081D0 (en) 2015-01-22 2015-03-11 Cilian Ag Use of enzymes with a wide pH activity range as medicaments for promoting digestion
US20180028454A1 (en) 2015-02-04 2018-02-01 Abbvie Inc. Pharmaceutical compositions and methods of use thereof to treat pancreatic enzyme insufficiency
DE102015114857A1 (de) * 2015-09-04 2017-03-09 Nordmark Arzneimittel Gmbh & Co. Kg Getränk, enthaltend eine pharmazeutische Zusammensetzung

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8421210D0 (en) * 1984-08-21 1984-09-26 Celltech Ltd Polypeptide and polypeptide composition
US4659667A (en) * 1985-02-26 1987-04-21 Miles Laboratories, Inc. Process to recover crystalline enzymes and crystalline enzymes produced thereby
US5108457A (en) * 1986-11-19 1992-04-28 The Clorox Company Enzymatic peracid bleaching system with modified enzyme
EP0305216B1 (fr) * 1987-08-28 1995-08-02 Novo Nordisk A/S Lipase recombinante de humicola et procédé de production de lipases recombinantes de humicola
ES2044718T3 (es) * 1989-12-21 1994-01-01 Novo Nordisk As Preparacion que contiene enzimas y detergente que contiene dicha preparacion.

Also Published As

Publication number Publication date
DE69131106T2 (de) 1999-11-18
JPH06501147A (ja) 1994-02-10
DE69131106D1 (de) 1999-05-12
DK173590D0 (da) 1990-07-19
US5614189A (en) 1997-03-25
JP3072853B2 (ja) 2000-08-07
ATE178492T1 (de) 1999-04-15
WO1991018623A1 (fr) 1991-12-12
CA2084184A1 (fr) 1991-12-07
EP0600868B1 (fr) 1999-04-07
EP0600868A1 (fr) 1994-06-15
AU645583B2 (en) 1994-01-20
AU8096491A (en) 1991-12-31
FI925530A (fi) 1992-12-04

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