DK172682B1 - Syntetisk polypeptid - Google Patents

Syntetisk polypeptid Download PDF

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Publication number
DK172682B1
DK172682B1 DK198401697A DK169784A DK172682B1 DK 172682 B1 DK172682 B1 DK 172682B1 DK 198401697 A DK198401697 A DK 198401697A DK 169784 A DK169784 A DK 169784A DK 172682 B1 DK172682 B1 DK 172682B1
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DK
Denmark
Prior art keywords
leu
glu
ala
ser
gln
Prior art date
Application number
DK198401697A
Other languages
Danish (da)
English (en)
Other versions
DK169784D0 (da
DK169784A (da
Inventor
Jean Edouard Frederic Rivier
Joachim Spiess
Wylie Walker Vale Jr
Original Assignee
Salk Inst For Biological Studi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Salk Inst For Biological Studi filed Critical Salk Inst For Biological Studi
Publication of DK169784D0 publication Critical patent/DK169784D0/da
Publication of DK169784A publication Critical patent/DK169784A/da
Application granted granted Critical
Publication of DK172682B1 publication Critical patent/DK172682B1/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/57509Corticotropin releasing factor [CRF] (Urotensin)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/2228Corticotropin releasing factor [CRF] (Urotensin)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Control Of Eletrric Generators (AREA)
  • Vehicle Body Suspensions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Control Of El Displays (AREA)
  • Bipolar Transistors (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK198401697A 1983-04-14 1984-03-27 Syntetisk polypeptid DK172682B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US48493183 1983-04-14
US06/484,931 US4489163A (en) 1983-04-14 1983-04-14 rCRF and analogs

Publications (3)

Publication Number Publication Date
DK169784D0 DK169784D0 (da) 1984-03-27
DK169784A DK169784A (da) 1984-10-15
DK172682B1 true DK172682B1 (da) 1999-05-25

Family

ID=23926236

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198401697A DK172682B1 (da) 1983-04-14 1984-03-27 Syntetisk polypeptid

Country Status (16)

Country Link
US (1) US4489163A (ja)
EP (1) EP0122798B1 (ja)
JP (1) JPH0689034B2 (ja)
KR (1) KR900006559B1 (ja)
AT (1) ATE96807T1 (ja)
AU (1) AU565699B2 (ja)
CA (1) CA1247602A (ja)
DE (1) DE3486238T2 (ja)
DK (1) DK172682B1 (ja)
ES (1) ES8606406A1 (ja)
GR (1) GR81467B (ja)
IE (1) IE61617B1 (ja)
IL (1) IL71326A (ja)
NZ (1) NZ207779A (ja)
PH (1) PH23123A (ja)
ZA (1) ZA842460B (ja)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0153845B1 (en) * 1984-02-23 1993-04-21 The Salk Institute For Biological Studies Crf analogs
FR2567524B1 (fr) * 1984-07-10 1987-11-27 Sanofi Sa Procede de synthese de la somatocrinine en phase liquide et peptides intermediaires
US4801612A (en) * 1986-07-03 1989-01-31 Regents Of The University Of California Method of inhibiting inflammatory response
DE3703340A1 (de) * 1987-02-04 1988-08-18 Dirck Dr Med Oppermann Pharmazeutische zubereitung zur behandlung der herzinsuffizienz
CA1341051C (en) * 1988-09-23 2000-07-11 Jean Edouard Frederic Rivier Crf antagonists
US5278146A (en) * 1988-09-30 1994-01-11 The Salk Institute For Biological Studies CRF analogs
CA1340964C (en) * 1988-09-30 2000-04-18 Jean E. F. Rivier Crf analogs
CA2002004A1 (en) * 1988-11-14 1990-05-14 Karl P. Lederis Fish crf
US5137871A (en) * 1989-07-28 1992-08-11 Regents Of The University Of California Treatment to reduce edema for brain and musculature injuries
US5488033A (en) * 1989-07-28 1996-01-30 The Regents Of The University Of California Treatment to reduce edema
DE3942925A1 (de) * 1989-12-23 1991-06-27 Swf Auto Electric Gmbh Elektrischer schalter, insbesondere blinkerschalter fuer kraftfahrzeuge
US5480869A (en) * 1990-01-09 1996-01-02 The Regents Of The University Of California Anti-inflammatory peptide analogs and treatment to inhibit vascular leakage in injured tissues
US5177060A (en) * 1990-01-09 1993-01-05 Regents Of The University Of California Anti-inflammatory peptides and treatment to inhibit vascular leakage in injured tissues
US5245009A (en) * 1990-03-23 1993-09-14 The Salk Institute For Biological Studies CRF antagonists
US5235036A (en) * 1991-05-31 1993-08-10 The Salk Institute For Biological Studies Crf analogs
US5374621A (en) * 1991-09-13 1994-12-20 Regents Of The University Of California Neurotensin method for inhibiting vascular leakage
US6495343B1 (en) 1993-06-18 2002-12-17 The Salk Institute For Biological Studies Cloning and recombinant production of CRF receptor(s)
US5728545A (en) * 1993-06-18 1998-03-17 The Salk Institute Of Biological Studies Cloning and recombinant production of CRF receptor (S)
US6638905B2 (en) * 1993-06-18 2003-10-28 The Salk Institute For Biological Studies Cloning and recombinant production of CFR receptor(s)
US6039956A (en) * 1994-09-12 2000-03-21 Pennsylvania, Trustees Of The University Of, The Corticotropin release inhibiting factor and methods of using same for treating behavioral symptoms in an anxiety disorder
CA2199734A1 (en) * 1994-09-12 1996-03-21 Fraser Aird Corticotropin release inhibiting factor and methods of using same
US6670140B2 (en) * 2001-03-06 2003-12-30 The Procter & Gamble Company Methods for identifying compounds for regulating muscle mass or function using corticotropin releasing factor receptors
US7141546B1 (en) 2001-08-01 2006-11-28 The Salk Institute For Biologicial Studies CRFR2 selective ligands
WO2003011823A2 (en) * 2001-08-01 2003-02-13 The Salk Institute For Biological Studies Crfr1 selective ligands
US20090035298A1 (en) * 2007-04-23 2009-02-05 Washington University In St. Louis Methods to treat alzheimer's disease or other amyloid beta accumulation associated disorders
AU2009241813A1 (en) * 2008-04-30 2009-11-05 Neutron Row Methods of using corticotropin-releasing factor for the treatment of cancer
WO2010149357A2 (en) 2009-06-24 2010-12-29 Stephen Evans-Freke Methods of using corticotropin-releasing factor for the treatment of cancer
WO2012088397A2 (en) 2010-12-22 2012-06-28 The Salk Institute For Biological Studies Cyclic crf antagonist peptides

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR67608E (fr) * 1955-02-22 1958-03-14 Variateur de vitesse, notamment pour cycles
GB2016015B (en) 1978-01-22 1982-05-06 Hayashibara Co Method of preparing interferon and preparations containing interferon
US4244946A (en) 1979-06-11 1981-01-13 The Salk Institute For Biological Studies Water-soluble peptides affecting gonadal function
US4415558A (en) 1981-06-08 1983-11-15 The Salk Institute For Biological Studies CRF And analogs
JPS58502180A (ja) 1981-11-23 1983-12-22 ユニヴアシテイ パテンツ,インコ−ポレイテツド Dna配列の転写の調節
GB2118190B (en) * 1982-04-13 1985-05-01 Erba Farmitalia Peptides with sauvagine-like activity

Also Published As

Publication number Publication date
NZ207779A (en) 1988-04-29
GR81467B (ja) 1984-12-11
KR900006559B1 (ko) 1990-09-13
EP0122798A3 (en) 1986-09-03
ZA842460B (en) 1984-11-28
IE61617B1 (en) 1994-11-16
EP0122798A2 (en) 1984-10-24
ATE96807T1 (de) 1993-11-15
ES8606406A1 (es) 1986-04-01
DE3486238T2 (de) 1994-03-03
IE840867L (en) 1984-10-14
KR840009075A (ko) 1984-12-24
DK169784D0 (da) 1984-03-27
IL71326A0 (en) 1984-06-29
AU565699B2 (en) 1987-09-24
JPS59199662A (ja) 1984-11-12
IL71326A (en) 1987-11-30
US4489163A (en) 1984-12-18
JPH0689034B2 (ja) 1994-11-09
AU2677784A (en) 1984-10-18
CA1247602A (en) 1988-12-28
PH23123A (en) 1989-05-05
ES531585A0 (es) 1986-04-01
DK169784A (da) 1984-10-15
EP0122798B1 (en) 1993-11-03
DE3486238D1 (de) 1993-12-09

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed
PUP Patent expired