DK171746B1 - Transdermalt afgivelsessystem - Google Patents

Transdermalt afgivelsessystem Download PDF

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Publication number
DK171746B1
DK171746B1 DK316788A DK316788A DK171746B1 DK 171746 B1 DK171746 B1 DK 171746B1 DK 316788 A DK316788 A DK 316788A DK 316788 A DK316788 A DK 316788A DK 171746 B1 DK171746 B1 DK 171746B1
Authority
DK
Denmark
Prior art keywords
alkyl
enantiomer
delivery system
transdermal delivery
amino
Prior art date
Application number
DK316788A
Other languages
Danish (da)
English (en)
Other versions
DK316788A (da
DK316788D0 (da
Inventor
John Michael Pawelchak
James Ronald Lawter
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of DK316788D0 publication Critical patent/DK316788D0/da
Publication of DK316788A publication Critical patent/DK316788A/da
Application granted granted Critical
Publication of DK171746B1 publication Critical patent/DK171746B1/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Hydrogenated Pyridines (AREA)
DK316788A 1987-06-12 1988-06-10 Transdermalt afgivelsessystem DK171746B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6184287A 1987-06-12 1987-06-12
US6184287 1987-06-12

Publications (3)

Publication Number Publication Date
DK316788D0 DK316788D0 (da) 1988-06-10
DK316788A DK316788A (da) 1988-12-13
DK171746B1 true DK171746B1 (da) 1997-05-05

Family

ID=22038497

Family Applications (1)

Application Number Title Priority Date Filing Date
DK316788A DK171746B1 (da) 1987-06-12 1988-06-10 Transdermalt afgivelsessystem

Country Status (16)

Country Link
EP (1) EP0294601B1 (ko)
JP (1) JP2654092B2 (ko)
KR (1) KR970000506B1 (ko)
AT (1) ATE84714T1 (ko)
AU (1) AU609142B2 (ko)
CA (1) CA1305418C (ko)
DE (1) DE3877630T2 (ko)
DK (1) DK171746B1 (ko)
ES (1) ES2043719T3 (ko)
GR (1) GR3006938T3 (ko)
IE (1) IE62735B1 (ko)
IL (1) IL86334A (ko)
NO (1) NO178096C (ko)
NZ (1) NZ224891A (ko)
PT (1) PT87704B (ko)
ZA (1) ZA884186B (ko)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5045553A (en) * 1987-06-24 1991-09-03 Fujisawa Pharmaceutical Company, Ltd. Pharmaceutical composition for percutaneous drug absorption and percutaneous drug absorption promoter
US6075024A (en) * 1991-11-27 2000-06-13 Sepracor Inc. Methods for treating infection using optically pure (S)-lomefloxacin
US5476854A (en) * 1991-11-27 1995-12-19 Sepracor Inc. Methods and compositions for treating bacterial infection using optically pure (R)-lomefloxacin
US5834496A (en) * 1991-12-02 1998-11-10 Sepracor, Inc. Methods for treating hypertension using optically pure S(-) felodipine
DE69333009T2 (de) * 1992-11-09 2003-12-04 Neurogesx, Inc. Transdermale verabreichung von ketorolac
NZ530227A (en) 2001-06-18 2006-09-29 Noven Pharma Enhanced drug delivery in transdermal systems
CN100444840C (zh) 2003-05-15 2008-12-24 罗斯坎普研究有限公司 减少淀粉样沉积、淀粉样神经毒性和小胶质增生的药物
EP2214666B1 (en) 2007-10-05 2013-12-11 Alzheimer's Institute of America, Inc. Method for reducing amyloid deposition, amyloid neurotoxicity, and microgliosis with (-)-nilvadipine enantiomer

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4338322A (en) * 1975-07-02 1982-07-06 Fujisawa Pharmaceutical Co., Ltd. 1,4-Dihydropyridine derivatives, pharmaceutical compositions containing same and methods of effecting vasodilation using same
US4284634A (en) * 1975-07-02 1981-08-18 Fujisawa Pharmaceutical Co., Ltd. 1,4-Dihydropyridine derivatives, and pharmaceutical method of the same
CA1117117A (en) * 1978-10-10 1982-01-26 Fujisawa Pharmaceutical Co., Ltd. 2-methyl-dihydropyridine compound, processes for preparation thereof and pharmaceutical composition comprising the same
JPS6016917A (ja) * 1983-07-08 1985-01-28 Yamanouchi Pharmaceut Co Ltd 塩酸ニカルジピンまたはニフエジピンの軟膏剤
JPS60258179A (ja) * 1984-06-04 1985-12-20 Yamanouchi Pharmaceut Co Ltd Ym−09730のジアステレオマ−aの右旋性光学異性体またはその酸付加塩,該化合物の製造方法および該化合物からなる医薬
DE3419128A1 (de) * 1984-05-23 1985-11-28 Bayer Ag, 5090 Leverkusen Dihydropyridinpraeparate und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
NO882559D0 (no) 1988-06-10
NO178096B (no) 1995-10-16
IE881749L (en) 1988-12-12
ES2043719T3 (es) 1994-01-01
AU1761088A (en) 1988-12-15
KR970000506B1 (ko) 1997-01-13
JP2654092B2 (ja) 1997-09-17
PT87704A (pt) 1988-07-01
DK316788A (da) 1988-12-13
JPS6413024A (en) 1989-01-17
PT87704B (pt) 1993-03-31
IL86334A (en) 1992-09-06
DK316788D0 (da) 1988-06-10
NO882559L (no) 1988-12-13
EP0294601A3 (en) 1989-10-11
CA1305418C (en) 1992-07-21
ZA884186B (en) 1989-03-29
EP0294601B1 (en) 1993-01-20
EP0294601A2 (en) 1988-12-14
AU609142B2 (en) 1991-04-26
DE3877630T2 (de) 1993-06-03
IE62735B1 (en) 1995-02-22
ATE84714T1 (de) 1993-02-15
NZ224891A (en) 1992-06-25
GR3006938T3 (ko) 1993-06-30
DE3877630D1 (de) 1993-03-04
NO178096C (no) 1996-01-24
KR890000090A (ko) 1989-03-11

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PUP Patent expired