DK171067B1 - Fremgangsmåde til fremstilling af 3-alkyl- eller -fluoralkyl-3-(4-pyridyl)piperidin-2,6-dioner - Google Patents

Fremgangsmåde til fremstilling af 3-alkyl- eller -fluoralkyl-3-(4-pyridyl)piperidin-2,6-dioner Download PDF

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Publication number
DK171067B1
DK171067B1 DK228990A DK228990A DK171067B1 DK 171067 B1 DK171067 B1 DK 171067B1 DK 228990 A DK228990 A DK 228990A DK 228990 A DK228990 A DK 228990A DK 171067 B1 DK171067 B1 DK 171067B1
Authority
DK
Denmark
Prior art keywords
reaction
potassium
alkyl
process according
carbon atoms
Prior art date
Application number
DK228990A
Other languages
Danish (da)
English (en)
Other versions
DK228990A (da
DK228990D0 (da
Inventor
Derek Wyndham Clissold
John Mann
Christopher Philip Thickitt
Original Assignee
British Tech Group
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB888806751A external-priority patent/GB8806751D0/en
Priority claimed from GB888825501A external-priority patent/GB8825501D0/en
Application filed by British Tech Group filed Critical British Tech Group
Publication of DK228990A publication Critical patent/DK228990A/da
Publication of DK228990D0 publication Critical patent/DK228990D0/da
Application granted granted Critical
Publication of DK171067B1 publication Critical patent/DK171067B1/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/86Oxygen atoms
    • C07D211/88Oxygen atoms attached in positions 2 and 6, e.g. glutarimide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK228990A 1988-03-22 1990-09-21 Fremgangsmåde til fremstilling af 3-alkyl- eller -fluoralkyl-3-(4-pyridyl)piperidin-2,6-dioner DK171067B1 (da)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GB888806751A GB8806751D0 (en) 1988-03-22 1988-03-22 Preparation of 2 6-dioxopiperidine derivatives
GB8806751 1988-03-22
GB888825501A GB8825501D0 (en) 1988-11-01 1988-11-01 Improvements relating to preparation of 2 6-dioxopiperidine derivatives
GB8825501 1988-11-01
GB8900308 1989-03-22
PCT/GB1989/000308 WO1989009216A1 (en) 1988-03-22 1989-03-22 Preparation of 2,6-dioxopiperidine derivatives

Publications (3)

Publication Number Publication Date
DK228990A DK228990A (da) 1990-09-21
DK228990D0 DK228990D0 (da) 1990-09-21
DK171067B1 true DK171067B1 (da) 1996-05-20

Family

ID=26293668

Family Applications (1)

Application Number Title Priority Date Filing Date
DK228990A DK171067B1 (da) 1988-03-22 1990-09-21 Fremgangsmåde til fremstilling af 3-alkyl- eller -fluoralkyl-3-(4-pyridyl)piperidin-2,6-dioner

Country Status (14)

Country Link
US (1) US5112976A (xx)
EP (1) EP0334633B1 (xx)
JP (1) JPH03503891A (xx)
KR (1) KR920003803B1 (xx)
AU (1) AU621602B2 (xx)
CA (1) CA1335290C (xx)
DE (1) DE68906449T2 (xx)
DK (1) DK171067B1 (xx)
FI (1) FI94637C (xx)
GB (1) GB2216524B (xx)
IE (1) IE64347B1 (xx)
IL (1) IL89631A (xx)
NO (1) NO176211C (xx)
WO (1) WO1989009216A1 (xx)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9602516D0 (en) * 1996-02-08 1996-04-10 Chiroscience Ltd Racemisation
KR970061867A (ko) * 1996-02-23 1997-09-12 박민수 글루탐산 유도체, 그의 약제학적으로 허용가능한 염 및 이를 유효성분으루 함유하는 항경련제
US9777116B2 (en) 2014-10-16 2017-10-03 International Business Machines Corporation Porous/nanoporous PHT

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2673205A (en) * 1951-02-13 1954-03-23 Ciba Pharm Prod Inc 3-disubstituted dioxopiperidines and the manufacture thereof
US2848455A (en) * 1955-07-18 1958-08-19 Ciba Pharm Prod Inc Alpha-(p-amino-phenyl)-alpha-lower alkyl glutarimides
US5071857A (en) * 1983-12-09 1991-12-10 National Research Development Corporation 2,6-dioxopiperidine derivatives, their preparation and pharmaceutical compositions containing them
GB8332954D0 (en) * 1983-12-09 1984-01-18 Foster A B A 2,6-dioxopiperidine derivative and pharmaceutical compositions
US4668689A (en) * 1984-07-19 1987-05-26 National Research Development Corporation Glutarimide derivatives for treating oestrogen-dependent tumors

Also Published As

Publication number Publication date
FI94637C (fi) 1995-10-10
IL89631A0 (en) 1989-09-10
IE890867L (en) 1989-09-22
NO904108L (no) 1990-09-20
JPH03503891A (ja) 1991-08-29
DE68906449T2 (de) 1993-09-02
NO176211B (no) 1994-11-14
DK228990A (da) 1990-09-21
DK228990D0 (da) 1990-09-21
FI94637B (fi) 1995-06-30
AU621602B2 (en) 1992-03-19
IE64347B1 (en) 1995-07-26
WO1989009216A1 (en) 1989-10-05
KR890014518A (ko) 1989-10-24
EP0334633B1 (en) 1993-05-12
DE68906449D1 (de) 1993-06-17
NO176211C (no) 1995-02-22
US5112976A (en) 1992-05-12
GB2216524B (en) 1991-06-12
GB2216524A (en) 1989-10-11
GB8906580D0 (en) 1989-05-04
EP0334633A1 (en) 1989-09-27
FI904673A0 (fi) 1990-09-21
IL89631A (en) 1993-05-13
KR920003803B1 (ko) 1992-05-15
CA1335290C (en) 1995-04-18
AU3345889A (en) 1989-10-16
NO904108D0 (no) 1990-09-20

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed