DK170379B1 - Fremgangsmåde og reaktor til udførelse af mikrobiologiske eller enzymatiske processer - Google Patents

Fremgangsmåde og reaktor til udførelse af mikrobiologiske eller enzymatiske processer Download PDF

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Publication number
DK170379B1
DK170379B1 DK519485A DK519485A DK170379B1 DK 170379 B1 DK170379 B1 DK 170379B1 DK 519485 A DK519485 A DK 519485A DK 519485 A DK519485 A DK 519485A DK 170379 B1 DK170379 B1 DK 170379B1
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DK
Denmark
Prior art keywords
tube
reactor
ascending
pipe
circulation
Prior art date
Application number
DK519485A
Other languages
Danish (da)
English (en)
Other versions
DK519485A (da
DK519485D0 (da
Inventor
Nicolaas Marius Ger Oosterhuis
Kees Koerts
Original Assignee
Suiker Unie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from NL8403497A external-priority patent/NL8403497A/nl
Priority claimed from NL8500602A external-priority patent/NL8500602A/nl
Application filed by Suiker Unie filed Critical Suiker Unie
Publication of DK519485D0 publication Critical patent/DK519485D0/da
Publication of DK519485A publication Critical patent/DK519485A/da
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0053—Details of the reactor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/18—Stationary reactors having moving elements inside
    • B01J19/1812—Tubular reactors
    • B01J19/1837—Loop-type reactors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/06—Tubular
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/02—Stirrer or mobile mixing elements
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/32—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of substances in solution
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
    • C12P19/06—Xanthan, i.e. Xanthomonas-type heteropolysaccharides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/58—Aldonic, ketoaldonic or saccharic acids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00049—Controlling or regulating processes
    • B01J2219/00051—Controlling the temperature
    • B01J2219/00074—Controlling the temperature by indirect heating or cooling employing heat exchange fluids
    • B01J2219/00076—Controlling the temperature by indirect heating or cooling employing heat exchange fluids with heat exchange elements inside the reactor
    • B01J2219/00085—Plates; Jackets; Cylinders
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/813—Continuous fermentation
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/818—Aeration or oxygen transfer technique
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/819—Fermentation vessels in series

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Sustainable Development (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
DK519485A 1984-11-15 1985-11-12 Fremgangsmåde og reaktor til udførelse af mikrobiologiske eller enzymatiske processer DK170379B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
NL8403497A NL8403497A (nl) 1984-11-15 1984-11-15 Werkwijze en inrichting voor het uitvoeren van een microbiologisch of enzymatisch proces.
NL8403497 1984-11-15
NL8500602A NL8500602A (nl) 1985-03-04 1985-03-04 Werkwijze voor de fermentatiebereiding van polysacchariden, in het bijzonder xanthaan.
NL8500602 1985-03-04

Publications (3)

Publication Number Publication Date
DK519485D0 DK519485D0 (da) 1985-11-12
DK519485A DK519485A (da) 1986-05-16
DK170379B1 true DK170379B1 (da) 1995-08-14

Family

ID=26645991

Family Applications (1)

Application Number Title Priority Date Filing Date
DK519485A DK170379B1 (da) 1984-11-15 1985-11-12 Fremgangsmåde og reaktor til udførelse af mikrobiologiske eller enzymatiske processer

Country Status (11)

Country Link
US (2) US4935348A (fr)
EP (1) EP0185407B1 (fr)
JP (1) JPH0687784B2 (fr)
AU (1) AU590226B2 (fr)
CA (1) CA1301101C (fr)
DE (1) DE3575742D1 (fr)
DK (1) DK170379B1 (fr)
FI (1) FI85983C (fr)
IE (1) IE58568B1 (fr)
NO (1) NO171117C (fr)
NZ (1) NZ214155A (fr)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8601495A (nl) * 1986-06-09 1988-01-04 Suiker Unie Werkwijze en reactorvat voor de fermentatiebereiding van polysacchariden, in het bijzonder xanthaan.
DE3732370A1 (de) * 1987-09-25 1989-04-06 Hoechst Ag Verfahren zur vermischung von lebenden zellen oder mikroorganismen mit einer viskosen fluessigkeit und mischungen, die nach diesem verfahren hergestellt wurden
US5196345A (en) * 1988-08-12 1993-03-23 Eastman Kodak Company Method for controlling the removal of acidic metal carbonyl hydride from product streams
CH677676A5 (fr) * 1989-04-07 1991-06-14 Sulzer Ag
GB8917963D0 (en) * 1989-08-05 1989-09-20 Scras Apparatus for repeated automatic execution of a thermal cycle for treatment of biological samples
DK163066C (da) 1989-08-07 1992-06-15 Dansk Bioprotein Fremgangsmaade og apparat til udfoerelse af en fermentering
US20040018949A1 (en) * 1990-11-05 2004-01-29 Wai Mun Lee Semiconductor process residue removal composition and process
AT394576B (de) * 1991-01-16 1992-05-11 Vogelbusch Gmbh Reaktor zur durchfuehrung biologischer reaktionen mittels biokatalysatoren
DE4133383A1 (de) * 1991-10-09 1993-04-29 Ulrich Dr Kulozik Verfahren und vorrichtung zur kontinuierlichen gewinnung von mikrobiellen fermentierungsprodukten und/oder zellmasse
CH683694A5 (fr) * 1991-12-20 1994-04-29 Nestle Sa Production de vinaigre.
CH683695A5 (fr) * 1992-04-09 1994-04-29 Nestle Sa Hydrolyse enzymatique.
US5342781A (en) * 1993-07-15 1994-08-30 Su Wei Wen W External-loop perfusion air-lift bioreactor
US5618689A (en) * 1995-05-25 1997-04-08 Nestec S.A. Enhanced procedures for preparing food hydrolysates
EP1183326B1 (fr) * 1999-05-18 2007-03-07 Ebbe Busch Larsen Fermentateur en forme de u et/ou buse incurvee en forme de u et mise en oeuvre du procede de fermentation
US7201884B2 (en) 2001-12-26 2007-04-10 E. I. Du Pont De Nemours And Company Process and apparatus for performing a gas-sparged reaction
US7344988B2 (en) * 2003-10-27 2008-03-18 Dupont Air Products Nanomaterials Llc Alumina abrasive for chemical mechanical polishing
BRPI0509301B1 (pt) * 2004-03-31 2017-04-11 Natureworks Llc processo para fermentação de açucares contendo sacarídeos oligoméricos
NZ534302A (en) * 2004-07-23 2007-10-26 John Brodie Matthews Process and apparatus for oxidising bitumen to modify its properties
US8648209B1 (en) * 2005-12-31 2014-02-11 Joseph P. Lastella Loop reactor for making biodiesel fuel
US10184103B2 (en) 2008-12-15 2019-01-22 Unibo A/S U-shape and/or nozzle U-loop fermentor and method of fermentation
CA2885803C (fr) 2012-10-08 2021-01-26 Calysta, Inc. Systemes de fermentation alimentes par un gaz
JP6623737B2 (ja) * 2015-12-15 2019-12-25 コニカミノルタ株式会社 光学フィルムの製造方法および製造装置
KR20190017871A (ko) 2016-06-17 2019-02-20 칼리스타, 인코포레이티드 가스 공급 발효 반응기, 시스템 및 프로세스
RU2760291C2 (ru) * 2016-12-13 2021-11-23 Юниверсити Оф Гавайи Способ и биореактор для продуктов ферментации газа
CN110382681A (zh) 2017-01-10 2019-10-25 凯利斯塔公司 利用垂直流动区的进气发酵反应器、系统和方法
CN110325630B (zh) * 2017-03-10 2023-10-10 陶氏环球技术有限责任公司 好氧发酵系统和方法
CN111107919B (zh) 2017-08-14 2021-12-21 凯利斯塔公司 利用气/液分离容器的进气发酵反应器、系统和方法

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2188192A (en) * 1936-05-04 1940-01-23 Scholler Heinrich Method of and apparatus for fermenting solutions
US3257362A (en) * 1960-11-21 1966-06-21 Phillips Petroleum Co Control of olefin polymerization reactions
FR1287771A (fr) * 1961-04-17 1962-03-16 Procédé pour l'obtention de produits de fermentation, en particulier de levure, et dispositif pour la mise en oeuvre de ce procédé
FR1556397A (fr) * 1967-12-29 1969-02-07
US3672953A (en) * 1970-02-09 1972-06-27 Mobil Oil Corp Process for growing cells of a microorganism on a carbon-containing liquid substrate
GB1353008A (en) * 1970-07-21 1974-05-15 Ici Ltd Fermentation method and fermenter
DE2118197A1 (de) * 1971-04-08 1972-10-19 Engelbart, Wilke, Dipl.-Chem., 1000 Berlin; Engelbart, Fritz, Dipl.-Ing., 3001 Änderten Verfahren zur Optimierung von chemischen Umsetzungen und biologischen Fermentationen und Vorrichtung zur Ausführung des Verfahrens
FR2209837A1 (en) * 1972-12-13 1974-07-05 Baranovsky Vladimir Tubular appts. for microorganism growing - medium being moved by propel-lers through froth dampers and heat exchangers
FR2259903A1 (en) * 1974-02-05 1975-08-29 Univ Moskovsk Continuous propagation of micro-organisms in a closed circuit - with accurately controlled process parameters and uniformity in operation
US3985622A (en) * 1975-01-30 1976-10-12 Phillips Petroleum Company Method and apparatus for conducting fermentation
GB1499410A (en) * 1975-05-06 1978-02-01 Univ Waterloo Method of fermentation using tubular fermentors incorporating wall scrapers
SU590331A1 (ru) * 1975-12-29 1978-01-30 Белорусский технологический институт им. С.М.Кирова Аппарат дл выращивани микроорганизмов
FR2364967A1 (fr) * 1976-09-16 1978-04-14 Phillips Petroleum Co Procede et dispositif pour effectuer une fermentation
US4181576A (en) * 1977-03-29 1980-01-01 Phillips Petroleum Company Fermentation method
SU653295A1 (ru) * 1977-04-15 1979-03-25 Предприятие П/Я Р-6729 Аппарат дл выращивани микроорганизмов
JPS5441381A (en) * 1977-09-06 1979-04-02 Kanegafuchi Chem Ind Co Ltd Aerobic culturing of microorganism
CA1135180A (fr) * 1979-03-30 1982-11-09 Charles B. Donaldson Appareil et methode de dispersion d'un gaz dans un liquide
DE3245312A1 (de) * 1982-12-08 1984-06-14 Hoechst Ag, 6230 Frankfurt Verfahren zum durchfuehren (bio-)chemischer reaktionen
EP0130210A1 (fr) * 1983-01-03 1985-01-09 Biosystem E Ab Appareil de production de methane
AU1338283A (en) * 1983-03-16 1984-10-09 Zentrale Finanz- Und Kommerz-A.G. Verfahren und vorrichtung zum zuchten von mikroorganismen in einer nahrsubstratlosung

Also Published As

Publication number Publication date
DE3575742D1 (de) 1990-03-08
AU4979285A (en) 1986-05-22
AU590226B2 (en) 1989-11-02
DK519485A (da) 1986-05-16
IE852782L (en) 1986-05-15
FI854458A (fi) 1986-05-16
NO171117B (no) 1992-10-19
JPS61173784A (ja) 1986-08-05
NO171117C (no) 1993-01-27
FI85983B (fi) 1992-03-13
IE58568B1 (en) 1993-10-06
FI854458A0 (fi) 1985-11-13
FI85983C (fi) 1992-06-25
US5073496A (en) 1991-12-17
CA1301101C (fr) 1992-05-19
EP0185407B1 (fr) 1990-01-31
US4935348A (en) 1990-06-19
EP0185407A2 (fr) 1986-06-25
DK519485D0 (da) 1985-11-12
NO854536L (no) 1986-05-16
JPH0687784B2 (ja) 1994-11-09
EP0185407A3 (en) 1986-08-27
NZ214155A (en) 1988-08-30

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