DK169334B1 - 7-(1-Pyrrolidinyl)-3-quinoloncarboxylsyrederivater, fremgangsmåder til deres fremstilling og deres anvendelse i lægemidler og dyrefodertilsætninger - Google Patents
7-(1-Pyrrolidinyl)-3-quinoloncarboxylsyrederivater, fremgangsmåder til deres fremstilling og deres anvendelse i lægemidler og dyrefodertilsætninger Download PDFInfo
- Publication number
- DK169334B1 DK169334B1 DK103687A DK103687A DK169334B1 DK 169334 B1 DK169334 B1 DK 169334B1 DK 103687 A DK103687 A DK 103687A DK 103687 A DK103687 A DK 103687A DK 169334 B1 DK169334 B1 DK 169334B1
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- DK
- Denmark
- Prior art keywords
- pyrrolidinyl
- carboxylic acid
- oxo
- acid derivatives
- cyclopropyl
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Fodder In General (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3606698 | 1986-03-01 | ||
| DE19863606698 DE3606698A1 (de) | 1986-03-01 | 1986-03-01 | 7-(1-pyrrolidinyl)-chinoloncarbonsaeure -derivate |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK103687D0 DK103687D0 (da) | 1987-02-27 |
| DK103687A DK103687A (da) | 1987-09-02 |
| DK169334B1 true DK169334B1 (da) | 1994-10-10 |
Family
ID=6295255
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK103687A DK169334B1 (da) | 1986-03-01 | 1987-02-27 | 7-(1-Pyrrolidinyl)-3-quinoloncarboxylsyrederivater, fremgangsmåder til deres fremstilling og deres anvendelse i lægemidler og dyrefodertilsætninger |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US4820716A (hu) |
| EP (1) | EP0235676B1 (hu) |
| JP (1) | JPH0784458B2 (hu) |
| KR (1) | KR950007590B1 (hu) |
| AT (1) | ATE53582T1 (hu) |
| CA (1) | CA1337564C (hu) |
| DE (2) | DE3606698A1 (hu) |
| DK (1) | DK169334B1 (hu) |
| ES (1) | ES2017651B3 (hu) |
| GR (1) | GR3000560T3 (hu) |
| HU (1) | HU208129B (hu) |
| IL (1) | IL81702A (hu) |
| ZA (1) | ZA871431B (hu) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5153204A (en) * | 1986-03-01 | 1992-10-06 | Bayer Aktiengesellschaft | 7-(1-Pyrrolidinyl)-quinolonecarboxylic acid derivatives |
| JPH0262875A (ja) * | 1988-05-23 | 1990-03-02 | Wakunaga Pharmaceut Co Ltd | 新規イソインドリン誘導体 |
| KR910003630B1 (ko) * | 1988-06-17 | 1991-06-07 | 한국과학기술원 | 벤조일 아세틱 에스테르 유도체 및 그 제조방법 |
| EP0997466A1 (en) * | 1988-10-24 | 2000-05-03 | PROCTER & GAMBLE PHARMACEUTICALS, INC. | Novel antimicrobial lactam-quinolones |
| CA2001203C (en) * | 1988-10-24 | 2001-02-13 | Thomas P. Demuth, Jr. | Novel antimicrobial dithiocarbamoyl quinolones |
| FR2673426B1 (fr) * | 1991-03-01 | 1993-07-16 | Bouchara Sa | Nouvelles quinolones, leur procede de preparation et les compositions en refermant. |
| FR2674247B1 (fr) * | 1991-03-19 | 1993-07-16 | Bouchara Sa | Nouvelles quinolones fluorees, leur procede de preparation et les compositions pharmaceutiques en renfermant. |
| US5330992A (en) * | 1992-10-23 | 1994-07-19 | Sterling Winthrop Inc. | 1-cyclopropyl-4-pyridyl-quinolinones |
| CN111087409B (zh) * | 2018-10-24 | 2021-06-08 | 江阴安博生物医药有限公司 | 一种喹诺酮类化合物及其制备方法和应用 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5746986A (en) * | 1980-09-02 | 1982-03-17 | Dai Ichi Seiyaku Co Ltd | Pyrido(1,2,3-de)(1,4)benzoxazine derivative |
| US4670444B1 (en) * | 1980-09-03 | 1999-02-09 | Bayer Ag | and-naphthyridine-3-carboxylic acids and antibacte7-amino-1-cyclopropyl-4-oxo-1,4-dihydro-quinoline-rial agents containing these compounds |
| US4620007A (en) * | 1980-09-03 | 1986-10-28 | Bayer Aktiengesellschaft | 6-fluoro-7-chloro-1-cyclopropyl-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid |
| US4499091A (en) * | 1982-03-31 | 1985-02-12 | Sterling Drug Inc. | 1-Amino (or substituted amino)-1,4-dihydro-4-oxo-6-fluoro-7-heterylquinoline-3-carboxylic acids and their use as antibacterial agents |
| DE3248507A1 (de) * | 1982-12-29 | 1984-07-05 | Bayer Ag, 5090 Leverkusen | Mikrobizide mittel auf chinoloncarbonsaeure basis |
| DE3318145A1 (de) * | 1983-05-18 | 1984-11-22 | Bayer Ag, 5090 Leverkusen | 7-amino-1-cyclopropyl-6,8-difluor-1,4-dihydro-4-oxo-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel |
| NZ208470A (en) * | 1983-07-18 | 1988-06-30 | Abbott Lab | 6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid derivatives and antibacterial compositions containing such |
| NZ210847A (en) * | 1984-01-26 | 1988-02-29 | Abbott Lab | Naphthyridine and pyridopyrimidine derivatives and pharmaceutical compositions |
| IL74244A (en) * | 1984-02-17 | 1988-06-30 | Warner Lambert Co | Quinoline derivatives,their preparation and pharmaceutical compositions containing them |
| EP0160578B1 (en) * | 1984-02-17 | 1989-11-23 | Daiichi Seiyaku Co., Ltd. | 1,8-naphthyridine derivatives |
| US4571396A (en) * | 1984-04-16 | 1986-02-18 | Warner-Lambert Company | Antibacterial agents |
| DE3420743A1 (de) * | 1984-06-04 | 1985-12-05 | Bayer Ag, 5090 Leverkusen | 7-amino-1-cyclopropyl-6,8-dihalogen-1,4-dihydro-4-oxo-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel |
| US4623650A (en) * | 1984-12-06 | 1986-11-18 | Pfizer Inc. | Antibiotic derivatives of 7-phenyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids |
| FR2574404B1 (fr) * | 1984-12-12 | 1987-04-24 | Provesan Sa | Derives 1-substitues de l'acide 6-fluoro-7-(pyrrol-1-yl)-1,4-dihydro-4-oxoquinoleine-3-carboxylique, leur preparation et leur application en tant que medicaments |
| DE3517535A1 (de) * | 1985-05-15 | 1986-11-20 | Bayer Ag, 5090 Leverkusen | 1-aryl-4-chinolon-3-carbonsaeuren |
-
1986
- 1986-03-01 DE DE19863606698 patent/DE3606698A1/de not_active Withdrawn
-
1987
- 1987-02-12 US US07/013,744 patent/US4820716A/en not_active Expired - Fee Related
- 1987-02-18 EP EP87102290A patent/EP0235676B1/de not_active Expired - Lifetime
- 1987-02-18 DE DE8787102290T patent/DE3763192D1/de not_active Expired - Lifetime
- 1987-02-18 ES ES87102290T patent/ES2017651B3/es not_active Expired - Lifetime
- 1987-02-18 AT AT87102290T patent/ATE53582T1/de active
- 1987-02-27 DK DK103687A patent/DK169334B1/da not_active IP Right Cessation
- 1987-02-27 CA CA000530762A patent/CA1337564C/en not_active Expired - Fee Related
- 1987-02-27 IL IL81702A patent/IL81702A/xx not_active IP Right Cessation
- 1987-02-27 ZA ZA871431A patent/ZA871431B/xx unknown
- 1987-02-27 HU HU87818A patent/HU208129B/hu not_active IP Right Cessation
- 1987-02-28 JP JP62044163A patent/JPH0784458B2/ja not_active Expired - Lifetime
- 1987-02-28 KR KR1019870001788A patent/KR950007590B1/ko not_active IP Right Cessation
-
1990
- 1990-06-14 GR GR90400330T patent/GR3000560T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2017651B3 (es) | 1991-03-01 |
| ATE53582T1 (de) | 1990-06-15 |
| GR3000560T3 (en) | 1991-07-31 |
| JPH0784458B2 (ja) | 1995-09-13 |
| DE3606698A1 (de) | 1987-09-03 |
| HU208129B (en) | 1993-08-30 |
| EP0235676B1 (de) | 1990-06-13 |
| JPS62207269A (ja) | 1987-09-11 |
| US4820716A (en) | 1989-04-11 |
| HUT43581A (en) | 1987-11-30 |
| EP0235676A3 (en) | 1987-11-25 |
| KR870008867A (ko) | 1987-10-21 |
| CA1337564C (en) | 1995-11-14 |
| IL81702A0 (en) | 1987-09-16 |
| DK103687A (da) | 1987-09-02 |
| DE3763192D1 (de) | 1990-07-19 |
| KR950007590B1 (ko) | 1995-07-12 |
| EP0235676A2 (de) | 1987-09-09 |
| IL81702A (en) | 1991-05-12 |
| ZA871431B (en) | 1987-08-20 |
| DK103687D0 (da) | 1987-02-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B1 | Patent granted (law 1993) | ||
| PBP | Patent lapsed |