DK1692206T3 - Fremgangsmåde til at fremstille carboxylsyrefunktionaliserede polymerer - Google Patents
Fremgangsmåde til at fremstille carboxylsyrefunktionaliserede polymererInfo
- Publication number
- DK1692206T3 DK1692206T3 DK04810369.1T DK04810369T DK1692206T3 DK 1692206 T3 DK1692206 T3 DK 1692206T3 DK 04810369 T DK04810369 T DK 04810369T DK 1692206 T3 DK1692206 T3 DK 1692206T3
- Authority
- DK
- Denmark
- Prior art keywords
- carboxylic acid
- polymer
- acid functionalized
- carboxylate salt
- treated
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
- C08G63/91—Polymers modified by chemical after-treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/765—Polymers containing oxygen
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F251/00—Macromolecular compounds obtained by polymerising monomers on to polysaccharides or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F261/00—Macromolecular compounds obtained by polymerising monomers on to polymers of oxygen-containing monomers as defined in group C08F16/00
- C08F261/02—Macromolecular compounds obtained by polymerising monomers on to polymers of oxygen-containing monomers as defined in group C08F16/00 on to polymers of unsaturated alcohols
- C08F261/04—Macromolecular compounds obtained by polymerising monomers on to polymers of oxygen-containing monomers as defined in group C08F16/00 on to polymers of unsaturated alcohols on to polymers of vinyl alcohol
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F265/00—Macromolecular compounds obtained by polymerising monomers on to polymers of unsaturated monocarboxylic acids or derivatives thereof as defined in group C08F20/00
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F271/00—Macromolecular compounds obtained by polymerising monomers on to polymers of nitrogen-containing monomers as defined in group C08F26/00
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F283/00—Macromolecular compounds obtained by polymerising monomers on to polymers provided for in subclass C08G
- C08F283/06—Macromolecular compounds obtained by polymerising monomers on to polymers provided for in subclass C08G on to polyethers, polyoxymethylenes or polyacetals
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F289/00—Macromolecular compounds obtained by polymerising monomers on to macromolecular compounds not provided for in groups C08F251/00 - C08F287/00
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F291/00—Macromolecular compounds obtained by polymerising monomers on to macromolecular compounds according to more than one of the groups C08F251/00 - C08F289/00
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/30—Post-polymerisation treatment, e.g. recovery, purification, drying
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/32—Polymers modified by chemical after-treatment
- C08G65/329—Polymers modified by chemical after-treatment with organic compounds
- C08G65/331—Polymers modified by chemical after-treatment with organic compounds containing oxygen
- C08G65/332—Polymers modified by chemical after-treatment with organic compounds containing oxygen containing carboxyl groups, or halides, or esters thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/32—Polymers modified by chemical after-treatment
- C08G65/329—Polymers modified by chemical after-treatment with organic compounds
- C08G65/331—Polymers modified by chemical after-treatment with organic compounds containing oxygen
- C08G65/332—Polymers modified by chemical after-treatment with organic compounds containing oxygen containing carboxyl groups, or halides, or esters thereof
- C08G65/3322—Polymers modified by chemical after-treatment with organic compounds containing oxygen containing carboxyl groups, or halides, or esters thereof acyclic
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/32—Polymers modified by chemical after-treatment
- C08G65/329—Polymers modified by chemical after-treatment with organic compounds
- C08G65/334—Polymers modified by chemical after-treatment with organic compounds containing sulfur
- C08G65/3344—Polymers modified by chemical after-treatment with organic compounds containing sulfur containing oxygen in addition to sulfur
- C08G65/3346—Polymers modified by chemical after-treatment with organic compounds containing sulfur containing oxygen in addition to sulfur having sulfur bound to carbon and oxygen
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Medicinal Preparation (AREA)
- Polyethers (AREA)
- Treatments Of Macromolecular Shaped Articles (AREA)
- Peptides Or Proteins (AREA)
- Polyamides (AREA)
- Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US51779403P | 2003-11-06 | 2003-11-06 | |
| PCT/US2004/036850 WO2005047366A1 (en) | 2003-11-06 | 2004-11-05 | Method of preparing carboxylic acid functionalized polymers |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1692206T3 true DK1692206T3 (da) | 2011-05-23 |
Family
ID=34590189
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK04810369.1T DK1692206T3 (da) | 2003-11-06 | 2004-11-05 | Fremgangsmåde til at fremstille carboxylsyrefunktionaliserede polymerer |
Country Status (17)
| Country | Link |
|---|---|
| US (5) | US20050214250A1 (da) |
| EP (1) | EP1692206B1 (da) |
| JP (1) | JP5101884B2 (da) |
| KR (1) | KR101157007B1 (da) |
| CN (1) | CN100580005C (da) |
| AT (1) | ATE465204T1 (da) |
| AU (1) | AU2004289992B2 (da) |
| CA (1) | CA2544697C (da) |
| CY (1) | CY1110303T1 (da) |
| DE (1) | DE602004026770D1 (da) |
| DK (1) | DK1692206T3 (da) |
| ES (1) | ES2342294T3 (da) |
| IL (1) | IL175406A (da) |
| PL (1) | PL1692206T3 (da) |
| PT (1) | PT1692206E (da) |
| SI (1) | SI1692206T1 (da) |
| WO (1) | WO2005047366A1 (da) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050214250A1 (en) * | 2003-11-06 | 2005-09-29 | Harris J M | Method of preparing carboxylic acid functionalized polymers |
| AU2005206549B2 (en) * | 2004-01-21 | 2011-09-15 | Nektar Therapeutics | Method of preparing propionic acid-terminated polymers |
| JP4920593B2 (ja) * | 2004-10-25 | 2012-04-18 | インテザイン テクノロジーズ， インコーポレイテッド | ヘテロ二官能性ポリ（エチレングリコール）およびそれらの使用 |
| US7989554B2 (en) * | 2006-01-10 | 2011-08-02 | Enzon Pharmaceuticals, Inc. | Reacting polyalkylene oxide with base, tertiary alkyl haloacetate, then acid to prepare polyalkylene oxide carboxylic acid |
| US8133707B2 (en) | 2006-01-17 | 2012-03-13 | Enzon Pharmaceuticals, Inc. | Methods of preparing activated polymers having alpha nitrogen groups |
| US7671067B2 (en) * | 2006-02-09 | 2010-03-02 | Enzon Pharmaceuticals, Inc. | Treatment of non-hodgkin's lymphomas with multi-arm polymeric conjugates of 7-ethyl-10-hydroxycamtothecin |
| US7462627B2 (en) * | 2006-02-09 | 2008-12-09 | Enzon Pharmaceuticals, Inc. | Multi-arm polymeric conjugates of 7-ethyl-10-hydroxycamptothecin for treatment of breast, colorectal, pancreatic, ovarian and lung cancers |
| US7560588B2 (en) | 2006-04-27 | 2009-07-14 | Intezyne Technologies, Inc. | Poly(ethylene glycol) containing chemically disparate endgroups |
| WO2008019214A1 (en) | 2006-08-04 | 2008-02-14 | Prolong Pharmaceuticals, Inc. | Modified erythropoietin |
| MX2009008549A (es) * | 2007-02-09 | 2009-08-18 | Enzon Pharmaceuticals Inc | Tratamiento de canceres resistentes o refractarios con conjugados polimericos de brazos multiples de 7-etil-10-hidroxicamptotecina. |
| CN101357986B (zh) * | 2007-06-13 | 2013-06-05 | 康达医药科技有限公司 | 聚乙二醇功能性衍生物和制造方法 |
| US20100056555A1 (en) * | 2008-08-29 | 2010-03-04 | Enzon Pharmaceuticals, Inc. | Method of treating ras associated cancer |
| WO2010037045A1 (en) | 2008-09-28 | 2010-04-01 | Nerites Corporation | Multi-armed catechol compound blends |
| CN102215688A (zh) * | 2008-10-21 | 2011-10-12 | 安龙制药公司 | 用7-乙基-10-羟基喜树碱的多臂聚合物对神经母细胞瘤的治疗 |
| EP2393880B1 (en) * | 2009-02-06 | 2015-01-07 | Kensey Nash Corporation | Multi-linked star-shaped polymers and synthetic methods therefor |
| CN105175623A (zh) * | 2010-05-06 | 2015-12-23 | 康奈尔大学 | 可调lcst聚合物及其制备方法 |
| EP2606884A1 (en) | 2011-12-21 | 2013-06-26 | Ecole Polytechnique Fédérale de Lausanne (EPFL) | Inhibitors of notch signaling pathway and use thereof in treatment of cancers |
| EP2983659B1 (en) | 2013-04-09 | 2019-11-20 | Massachusetts Institute of Technology | Drug delivery polymer and uses thereof |
| US9447129B2 (en) | 2014-02-07 | 2016-09-20 | Massachusetts Institute Of Technology | Suprametallogels and uses thereof |
| WO2016167759A1 (en) * | 2015-04-15 | 2016-10-20 | Multisorb Technologies, Inc. | Surface modification of a resin |
| JP6777390B2 (ja) * | 2015-10-30 | 2020-10-28 | 株式会社日本触媒 | 生体適合性医療用材料 |
| EP3187254B1 (en) * | 2015-12-30 | 2020-09-02 | Italmatch SC, LLC | Polymeric emulsifier and lubricity additives for aqueous metal removal, forming, rolling or other applications |
| US10105449B2 (en) | 2016-06-07 | 2018-10-23 | Massachusetts Institute Of Technology | Drug delivery polymers and uses thereof |
| WO2018039577A1 (en) | 2016-08-26 | 2018-03-01 | Massachusetts Institute Of Technology | Bottlebrush polymers and uses thereof |
| WO2018067702A1 (en) | 2016-10-04 | 2018-04-12 | Massachusetts Institute Of Technology | Bottlebrush copolymers and uses thereof |
| JP6935059B2 (ja) * | 2017-03-30 | 2021-09-15 | 日油株式会社 | カルボキシル基を一つ有するポリエチレングリコールの精製方法 |
| JP7158143B2 (ja) * | 2017-04-13 | 2022-10-21 | 株式会社日本触媒 | 生体適合性医療用材料 |
| KR20200027518A (ko) | 2017-06-30 | 2020-03-12 | 메사추세츠 인스티튜트 오브 테크놀로지 | 분지형 다관능성 거대단량체 및 관련 중합체 및 그의 용도 |
| EP3645600A1 (en) | 2017-06-30 | 2020-05-06 | Massachusetts Institute of Technology | Core-to-surface polymerization for the synthesis of star polymers and uses thereof |
| US11752221B2 (en) | 2017-06-30 | 2023-09-12 | Massachusetts Institute Of Technology | Brush-arm star polymer imaging agents and uses thereof |
| CA3102129A1 (en) | 2018-06-21 | 2019-12-26 | Cellestia Biotech Ag | Process for making amino diaryl ethers and amino diaryl ethers hydrochloride salts |
| US10988491B2 (en) | 2018-08-17 | 2021-04-27 | Massachusetts Institute Of Technology | Degradable polymers of a cyclic silyl ether and uses thereof |
| WO2020203583A1 (ja) * | 2019-03-29 | 2020-10-08 | 日油株式会社 | 末端カルボキシル基含有ポリエチレングリコールの製造方法および活性化ポリエチレングリコールの製造方法 |
| SG11202110545TA (en) | 2019-04-10 | 2021-10-28 | Cellestia Biotech Ag | Inhibitors of notch signalling pathway and use thereof in treatment of cancers |
| WO2021141662A1 (en) | 2020-01-10 | 2021-07-15 | Massachusetts Institute Of Technology | Proteolysis targeting chimeric molecules (protacs) with functional handles and uses thereof |
| WO2021255487A2 (en) | 2020-06-19 | 2021-12-23 | Debreceni Egyetem | Zn-air rechargeable battery |
| EP4008324A1 (en) | 2020-12-07 | 2022-06-08 | Cellestia Biotech AG | Combinations comprising an inhibitor of an anti-apoptotic protein, such as bcl-2, bcl-xl, bclw or mcl-1, and a notch signaling pathway inhibitor for treating cancer |
| US20240041884A1 (en) | 2020-12-07 | 2024-02-08 | Cellestia Biotech Ag | Pharmaceutical Combinations for Treating Cancer |
| CN117794536A (zh) | 2021-06-02 | 2024-03-29 | 塞莱斯蒂亚生物技术股份公司 | 在治疗自身免疫性和炎症性疾病的方法中使用的化合物 |
| EP4429661A1 (en) | 2021-11-08 | 2024-09-18 | Cellestia Biotech AG | Pharmaceutical combinations for treating cancer |
| WO2023121753A1 (en) | 2021-12-20 | 2023-06-29 | Massachusetts Institute Of Technology | Biomolecule-polymer-pharmaceutical agent conjugates for delivering the pharmaceutical agent |
| EP4223292A1 (en) | 2022-02-07 | 2023-08-09 | Cellestia Biotech AG | Pharmaceutical combinations for treating cancer |
| CN115193363B (zh) * | 2022-09-16 | 2023-02-24 | 世名(苏州)新材料研究院有限公司 | 高酸值低酯值氧化蜡、其制备工艺及由其制得的酯化蜡 |
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| US4721579A (en) * | 1980-08-15 | 1988-01-26 | Basf Corporation | Sodium carboxymethyl derivatives of polyoxyalkylene glycols, their production, and use in functional fluids |
| DE3032061C1 (de) * | 1980-08-26 | 1982-06-09 | Chem-y, Fabriek van Chemische Produkten B.V., Bodegraven | Verfahren zur Herstellung eines verpumpbaren oberflaechenaktiven Produktes auf Basis von Polyaetheressigsaeuren |
| DE3120195C2 (de) * | 1981-05-21 | 1986-09-04 | Degussa Ag, 6000 Frankfurt | Polymere Ammoniumverbindungen mit kieselsäureartigem Grundgerüst, Verfahren zu ihrer Herstellung und Verwendung |
| JPH04199152A (ja) * | 1990-11-29 | 1992-07-20 | Toshiba Corp | 感光性組成物 |
| US5483008A (en) * | 1992-02-07 | 1996-01-09 | Research Development Corporation Of Japan | Polyether having heterofunctional groups at both ends, process for the preparation thereof and polymerization initiator therefor |
| US5278303A (en) | 1992-06-12 | 1994-01-11 | University Of Toronto Innovations Foundation | Polymer-supported solution synthesis of oligosaccharides |
| JP3236087B2 (ja) * | 1992-10-26 | 2001-12-04 | 株式会社トクヤマ | 重合性磁性流体製造用界面活性剤 |
| US5605976A (en) * | 1995-05-15 | 1997-02-25 | Enzon, Inc. | Method of preparing polyalkylene oxide carboxylic acids |
| US5919455A (en) * | 1993-10-27 | 1999-07-06 | Enzon, Inc. | Non-antigenic branched polymer conjugates |
| US5693609A (en) | 1994-11-17 | 1997-12-02 | Eli Lilly And Company | Acylated insulin analogs |
| US5932462A (en) | 1995-01-10 | 1999-08-03 | Shearwater Polymers, Inc. | Multiarmed, monofunctional, polymer for coupling to molecules and surfaces |
| US5672662A (en) | 1995-07-07 | 1997-09-30 | Shearwater Polymers, Inc. | Poly(ethylene glycol) and related polymers monosubstituted with propionic or butanoic acids and functional derivatives thereof for biotechnical applications |
| JPH1087815A (ja) * | 1996-08-22 | 1998-04-07 | Enzon Inc | ポリアルキレンオキシドカルボン酸の改良製造方法 |
| JP3855344B2 (ja) * | 1997-02-19 | 2006-12-06 | 日本油脂株式会社 | ポリオキシアルキレンカルボン酸の製造方法 |
| US6448369B1 (en) * | 1997-11-06 | 2002-09-10 | Shearwater Corporation | Heterobifunctional poly(ethylene glycol) derivatives and methods for their preparation |
| DK1061954T3 (da) | 1998-03-12 | 2004-10-18 | Nektar Therapeutics Al Corp | Polyethylenglycolderivater med proximale reaktive grupper |
| DE19928128C1 (de) * | 1999-06-19 | 2000-11-30 | Clariant Gmbh | Verfahren zur Herstellung von Ethercarbonsäuren mit niedrigem Restalkohol |
| BR9917517A (pt) * | 1999-10-08 | 2002-07-30 | Shearwater Corp | Derivados poliméricos heterobifuncionais e processo para a preparação dos mesmos |
| TWI246524B (en) | 2001-01-19 | 2006-01-01 | Shearwater Corp | Multi-arm block copolymers as drug delivery vehicles |
| ATE344289T1 (de) | 2002-07-24 | 2006-11-15 | Hoffmann La Roche | Polyethylenglykol-aldehydderivate |
| US20050214250A1 (en) * | 2003-11-06 | 2005-09-29 | Harris J M | Method of preparing carboxylic acid functionalized polymers |
-
2004
- 2004-11-04 US US10/982,303 patent/US20050214250A1/en not_active Abandoned
- 2004-11-05 PL PL04810369T patent/PL1692206T3/pl unknown
- 2004-11-05 EP EP04810369A patent/EP1692206B1/en active Active
- 2004-11-05 SI SI200431461T patent/SI1692206T1/sl unknown
- 2004-11-05 KR KR1020067008804A patent/KR101157007B1/ko active IP Right Grant
- 2004-11-05 CN CN200480039882A patent/CN100580005C/zh active Active
- 2004-11-05 AU AU2004289992A patent/AU2004289992B2/en active Active
- 2004-11-05 WO PCT/US2004/036850 patent/WO2005047366A1/en active Application Filing
- 2004-11-05 ES ES04810369T patent/ES2342294T3/es active Active
- 2004-11-05 DE DE602004026770T patent/DE602004026770D1/de active Active
- 2004-11-05 JP JP2006539659A patent/JP5101884B2/ja active Active
- 2004-11-05 PT PT04810369T patent/PT1692206E/pt unknown
- 2004-11-05 AT AT04810369T patent/ATE465204T1/de active
- 2004-11-05 CA CA2544697A patent/CA2544697C/en active Active
- 2004-11-05 DK DK04810369.1T patent/DK1692206T3/da active
-
2006
- 2006-05-04 IL IL175406A patent/IL175406A/en active IP Right Grant
-
2010
- 2010-07-09 CY CY20101100646T patent/CY1110303T1/el unknown
-
2011
- 2011-02-09 US US13/023,960 patent/US8067505B2/en active Active
- 2011-10-21 US US13/279,134 patent/US20120041155A1/en not_active Abandoned
-
2013
- 2013-06-19 US US13/922,020 patent/US10011682B2/en active Active
-
2018
- 2018-06-05 US US16/000,561 patent/US11111335B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| IL175406A0 (en) | 2006-09-05 |
| EP1692206A1 (en) | 2006-08-23 |
| US11111335B2 (en) | 2021-09-07 |
| AU2004289992B2 (en) | 2010-05-20 |
| ES2342294T3 (es) | 2010-07-05 |
| US8067505B2 (en) | 2011-11-29 |
| PL1692206T3 (pl) | 2011-06-30 |
| US20050214250A1 (en) | 2005-09-29 |
| SI1692206T1 (sl) | 2010-08-31 |
| CA2544697A1 (en) | 2005-05-26 |
| DE602004026770D1 (de) | 2010-06-02 |
| CY1110303T1 (el) | 2015-01-14 |
| US10011682B2 (en) | 2018-07-03 |
| PT1692206E (pt) | 2010-07-19 |
| US20130281634A1 (en) | 2013-10-24 |
| KR20060117936A (ko) | 2006-11-17 |
| WO2005047366A1 (en) | 2005-05-26 |
| US20110130539A1 (en) | 2011-06-02 |
| EP1692206B1 (en) | 2010-04-21 |
| CN1902257A (zh) | 2007-01-24 |
| US20180282476A1 (en) | 2018-10-04 |
| CN100580005C (zh) | 2010-01-13 |
| US20120041155A1 (en) | 2012-02-16 |
| JP5101884B2 (ja) | 2012-12-19 |
| KR101157007B1 (ko) | 2012-06-21 |
| AU2004289992A1 (en) | 2005-05-26 |
| JP2007510800A (ja) | 2007-04-26 |
| ATE465204T1 (de) | 2010-05-15 |
| IL175406A (en) | 2012-01-31 |
| CA2544697C (en) | 2012-10-16 |
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