DK1682907T3 - Fremgangsmåde til identificering af en person med risiko for udvikling af hjerteinsufficiens ved hjælp af bestemmelse af niveauet af galectin-3 eller thrombospondin-2 - Google Patents

Fremgangsmåde til identificering af en person med risiko for udvikling af hjerteinsufficiens ved hjælp af bestemmelse af niveauet af galectin-3 eller thrombospondin-2

Info

Publication number
DK1682907T3
DK1682907T3 DK04765681.4T DK04765681T DK1682907T3 DK 1682907 T3 DK1682907 T3 DK 1682907T3 DK 04765681 T DK04765681 T DK 04765681T DK 1682907 T3 DK1682907 T3 DK 1682907T3
Authority
DK
Denmark
Prior art keywords
level
risk
determining
galectin
thrombospondin
Prior art date
Application number
DK04765681.4T
Other languages
Danish (da)
English (en)
Inventor
Yigal M Pinto
Original Assignee
Univ Maastricht
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Maastricht filed Critical Univ Maastricht
Application granted granted Critical
Publication of DK1682907T3 publication Critical patent/DK1682907T3/da

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6887—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/9453—Cardioregulators, e.g. antihypotensives, antiarrhythmics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4703—Regulators; Modulating activity
    • G01N2333/4704—Inhibitors; Supressors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4724—Lectins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4728—Details alpha-Glycoproteins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/32—Cardiovascular disorders
    • G01N2800/321—Arterial hypertension
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/32—Cardiovascular disorders
    • G01N2800/325—Heart failure or cardiac arrest, e.g. cardiomyopathy, congestive heart failure
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/50—Determining the risk of developing a disease
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/811—Test for named disease, body condition or organ function

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hospice & Palliative Care (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Electrotherapy Devices (AREA)
DK04765681.4T 2003-10-09 2004-09-27 Fremgangsmåde til identificering af en person med risiko for udvikling af hjerteinsufficiens ved hjælp af bestemmelse af niveauet af galectin-3 eller thrombospondin-2 DK1682907T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP03078161A EP1522857A1 (en) 2003-10-09 2003-10-09 Method for identifying a subject at risk of developing heart failure by determining the level of galectin-3 or thrombospondin-2
PCT/EP2004/010879 WO2005040817A1 (en) 2003-10-09 2004-09-27 Method for identifying a subject at risk of developing heart failure by determining the level of galectin-3 or thrombospondin-2

Publications (1)

Publication Number Publication Date
DK1682907T3 true DK1682907T3 (da) 2012-08-13

Family

ID=34306912

Family Applications (2)

Application Number Title Priority Date Filing Date
DK04765681.4T DK1682907T3 (da) 2003-10-09 2004-09-27 Fremgangsmåde til identificering af en person med risiko for udvikling af hjerteinsufficiens ved hjælp af bestemmelse af niveauet af galectin-3 eller thrombospondin-2
DK10186331.4T DK2317324T3 (en) 2003-10-09 2004-09-27 A method of identifying an individual at risk of developing heart failure by determining the level of galectin-3 or thrombospondin-2

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK10186331.4T DK2317324T3 (en) 2003-10-09 2004-09-27 A method of identifying an individual at risk of developing heart failure by determining the level of galectin-3 or thrombospondin-2

Country Status (14)

Country Link
US (5) US7888137B2 (cg-RX-API-DMAC7.html)
EP (4) EP1522857A1 (cg-RX-API-DMAC7.html)
JP (5) JP4840744B2 (cg-RX-API-DMAC7.html)
CN (2) CN1879022B (cg-RX-API-DMAC7.html)
AT (1) ATE532073T1 (cg-RX-API-DMAC7.html)
AU (2) AU2004284496C1 (cg-RX-API-DMAC7.html)
CA (2) CA2542033C (cg-RX-API-DMAC7.html)
CY (2) CY1112359T1 (cg-RX-API-DMAC7.html)
DK (2) DK1682907T3 (cg-RX-API-DMAC7.html)
ES (2) ES2530567T3 (cg-RX-API-DMAC7.html)
PL (2) PL2317324T3 (cg-RX-API-DMAC7.html)
PT (2) PT2317324E (cg-RX-API-DMAC7.html)
SI (2) SI1682907T1 (cg-RX-API-DMAC7.html)
WO (1) WO2005040817A1 (cg-RX-API-DMAC7.html)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1522857A1 (en) * 2003-10-09 2005-04-13 Universiteit Maastricht Method for identifying a subject at risk of developing heart failure by determining the level of galectin-3 or thrombospondin-2
JP2010504089A (ja) * 2006-09-25 2010-02-12 ユニフェルジテイト・マーストリヒト 心不全を発生させる危険がある被検者を診断および／または処置するための手段および方法
EP2109688A4 (en) * 2007-01-23 2010-02-17 Univ Virginia GALECTIN-3 BINDING PROTEIN AS BIOMARKER FOR HEART CIRCULATION DISEASES
JP2010539493A (ja) * 2007-09-17 2010-12-16 ビージー メディシン， インコーポレイテッド ペルオキシソーム−増殖因子−活性化因子−レセプター−γアゴニストもしくはチアゾリジンジオンで処置されたか処置される可能性のある患者における欝血性心リスクの評価
EP3971570A3 (en) * 2008-10-29 2022-11-09 BG Medicine, Inc. Galectin-3 immunoassay
MX2012002371A (es) * 2009-08-25 2012-06-08 Bg Medicine Inc Galectina-3 y terapia de resincronizacion cardiaca.
US20120029003A1 (en) * 2010-07-02 2012-02-02 Bg Medicine, Inc. Galectin-3 and statin therapy
US8703433B2 (en) * 2010-10-18 2014-04-22 Hideaki Hara Marker for amyotrophic lateral sclerosis, and use thereof
EP2460890A1 (en) * 2010-12-01 2012-06-06 Max-Delbrück-Centrum für Molekulare Medizin (MDC) Gpnmb/Osteoactivin as a drug target and biomarker in cardiac diseases
EP2671080A1 (en) * 2011-01-31 2013-12-11 BG Medicine, Inc. Use of galectin-3 for detecting and prognosing heart failure after acute coronary syndrome
ES2897419T3 (es) 2011-03-17 2022-03-01 Critical Care Diagnostics Inc Procedimientos de predicción del riesgo de un resultado clínico adverso
AR086543A1 (es) * 2011-05-25 2014-01-08 Bg Medicine Inc Inhibidores de galectina-3 y metodos de uso de los mismos, composicion farmaceutica
BR112014012823A2 (pt) * 2011-12-08 2015-09-29 Isaac Eliaz redução dos níveis de galectina-3 por meio de plasmaferese
ES2742291T3 (es) * 2012-09-27 2020-02-13 Siemens Healthcare Diagnostics Inc Cistatina C y Galectina-3 como biomarcadores para la hipertensión arterial pulmonar
JP6366598B2 (ja) * 2012-11-15 2018-08-01 タフツ ユニバーシティー ガレクチンタンパク質阻害剤を用いて被験体の眼の血管新生または繊維症を処置し、調節し、または、予防する方法、組成物、およびキット
WO2016113719A1 (en) 2015-01-18 2016-07-21 Diasorin S.P.A. Use of 1,25-dihydroxyvitamin d values in ratio with pth as a prognostic biomarker
US10688565B2 (en) * 2015-05-28 2020-06-23 Kyocera Corporation Cutting tool
CN112553335A (zh) * 2020-12-17 2021-03-26 核工业总医院 肾细胞癌生物标志物及其应用

Family Cites Families (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4632901A (en) * 1984-05-11 1986-12-30 Hybritech Incorporated Method and apparatus for immunoassays
US4946778A (en) * 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
US4704692A (en) * 1986-09-02 1987-11-03 Ladner Robert C Computer based system and method for determining and displaying possible chemical structures for converting double- or multiple-chain polypeptides to single-chain polypeptides
US5091513A (en) * 1987-05-21 1992-02-25 Creative Biomolecules, Inc. Biosynthetic antibody binding sites
US5132405A (en) * 1987-05-21 1992-07-21 Creative Biomolecules, Inc. Biosynthetic antibody binding sites
AU2684488A (en) * 1988-06-27 1990-01-04 Carter-Wallace, Inc. Test device and method for colored particle immunoassay
US20010051350A1 (en) * 1995-05-02 2001-12-13 Albert Nazareth Diagnostic detection device and method
BE1010935A7 (nl) * 1997-02-19 1999-03-02 Delanghe Joris Richard Siegfri Fenotypering van humaan haptoglobine in serum of plasma door middel van quantitatieve agglutinatie met streptococcus antigenen.
AU7590198A (en) * 1997-06-10 1998-12-30 Medlyte Diagnostics, Inc. Methods for early detection of heart disease
US20060166276A1 (en) * 1997-09-05 2006-07-27 Lung Health Diagnostics Pty Ltd Method of diagnosis and agents useful for same
IL134880A0 (en) * 1997-09-05 2001-05-20 Univ Southern Australia A method of diagnosis
ATE298423T1 (de) * 1997-10-24 2005-07-15 Shionogi & Co Verfahren zur inhibierung des abbaus von natriuretischen peptiden und verbesserte methode zum bestimmen der natriuretischen peptide
ATE332144T1 (de) * 1998-04-02 2006-07-15 Genentech Inc Behandlung von herzhypertrophie
RU2218568C2 (ru) * 1999-01-29 2003-12-10 Роше Диагностикс Гмбх Способ обнаружения n-концевого про-мнп
JP2003504088A (ja) * 1999-02-19 2003-02-04 ザ ユニヴァーシティー オブ アイオワ リサーチ ファンデーション 黄斑変性に関する診断および治療
JP2003507076A (ja) * 1999-08-20 2003-02-25 ボード オブ リージェンツ， ザ ユニバーシティ オブ テキサス システム 心臓の遺伝子発現の調節におけるｈｄａｃ４およびｈｄａｃ５
AU2001236589A1 (en) 2000-02-04 2001-08-14 Aeomica, Inc. Methods and apparatus for high-throughput detection and characterization of alternatively spliced genes
AU2001251351A1 (en) 2000-04-05 2001-10-23 Incyte Genomics, Inc. Genes expressed in foam cell differentiation
KR100395254B1 (ko) * 2000-10-30 2003-08-21 (주)자리타 바이오텍 종양 발생 예측 키트
WO2002038794A2 (en) * 2000-11-09 2002-05-16 The Brigham And Women's Hospital, Inc. Cardiovascular disease diagnostic and therapeutic targets
WO2002039122A2 (en) * 2000-11-09 2002-05-16 Vitivity, Inc. Methods for the identification and the treatment of cardiovascular disease
CA2431861A1 (en) * 2000-12-08 2002-06-13 Curagen Corporation Method of detecting and treating tuberous sclerosis complex associated disorders
JP4035562B2 (ja) * 2001-01-31 2008-01-23 国立大学法人富山大学 ガレクチン−３誘導能を利用した物質のスクリーニング方法、肝の状態の診断方法およびこれらの方法を利用したキット
CA2441086A1 (en) 2001-03-19 2002-09-26 Wisconsin Alumni Research Foundation Identification of gene expression alterations underlying the aging process in mammals
US20060019235A1 (en) 2001-07-02 2006-01-26 The Board Of Trustees Of The Leland Stanford Junior University Molecular and functional profiling using a cellular microarray
US7447594B2 (en) 2001-07-10 2008-11-04 Ocimum Biosolutions, Inc. Molecular cardiotoxicology modeling
US20030099958A1 (en) * 2001-09-05 2003-05-29 Vitivity, Inc. Diagnosis and treatment of vascular disease
GB0124145D0 (en) 2001-10-08 2001-11-28 Bayer Ag Genes and proteins for prevention,prediction,prognosis and therapy of cardiovascular disease
US20060141493A1 (en) 2001-11-09 2006-06-29 Duke University Office Of Science And Technology Atherosclerotic phenotype determinative genes and methods for using the same
WO2003095667A2 (en) * 2002-05-13 2003-11-20 Arexis Ab Autoimmune conditions and nadph oxidase defects
AU2003290537A1 (en) 2002-10-24 2004-05-13 Duke University Binary prediction tree modeling with many predictors and its uses in clinical and genomic applications
US7611839B2 (en) 2002-11-21 2009-11-03 Wyeth Methods for diagnosing RCC and other solid tumors
EP1431399A1 (en) * 2002-12-20 2004-06-23 Clinigenetics Methods and composition for identifying therapeutic agents of atherosclerotic plaque lesions
US6889083B2 (en) * 2003-04-21 2005-05-03 Medtronic, Inc. Atrial tracking recovery to restore cardiac resynchronization therapy in dual chamber tracking modes
WO2005020784A2 (en) 2003-05-23 2005-03-10 Mount Sinai School Of Medicine Of New York University Surrogate cell gene expression signatures for evaluating the physical state of a subject
US20060257946A1 (en) 2003-06-06 2006-11-16 Ciphergen Biosystems, Inc Serum biomarkers in ischaemic heart disease
US20050106100A1 (en) 2003-09-03 2005-05-19 Harris Thomas D. Compounds containing matrix metalloproteinase substrates and methods of their use
EP1560025A3 (en) * 2003-10-03 2011-09-07 F. Hoffmann-La Roche AG Specific markers for diabetes
EP1522857A1 (en) * 2003-10-09 2005-04-13 Universiteit Maastricht Method for identifying a subject at risk of developing heart failure by determining the level of galectin-3 or thrombospondin-2
DE10347436B4 (de) * 2003-10-13 2007-08-02 Johann Wolfgang Goethe-Universität Frankfurt am Main In vitro Verfahren zur Diagnose der kardiovaskulären Funktionalität von Blut-abgeleiteter zirkulierender Vorläuferzellen (BDP)
US20060019890A1 (en) 2004-01-15 2006-01-26 Kapoun Ann M Method for treating cardiac remodeling following myocardial injury
WO2006026074A2 (en) 2004-08-04 2006-03-09 Duke University Atherosclerotic phenotype determinative genes and methods for using the same
US20090258002A1 (en) 2005-02-01 2009-10-15 Government Of The Us, As Represented By The Secretary, Department Of Health And Human Services Biomarkers for Tissue Status
WO2006102497A2 (en) 2005-03-22 2006-09-28 The Board Of Trustees Of The Leland Stanford Junior University Methods and compositions for diagnosis, monitoring and development of therapeutics for treatment of atherosclerotic disease
US7632634B2 (en) 2005-04-15 2009-12-15 University Of Maryland Biotechnology Institute Method and assay for early diagnosis of prostate cancer
US9592970B2 (en) * 2008-07-17 2017-03-14 Toby D. Henderson Robotic gantry with end effector for product lifting
EP3971570A3 (en) * 2008-10-29 2022-11-09 BG Medicine, Inc. Galectin-3 immunoassay
MX2012002371A (es) * 2009-08-25 2012-06-08 Bg Medicine Inc Galectina-3 y terapia de resincronizacion cardiaca.

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AU2009227844A1 (en) 2009-11-26
HK1184534A1 (zh) 2014-01-24
DK2317324T3 (en) 2015-02-16
CA2542033C (en) 2014-04-29
JP2007508527A (ja) 2007-04-05
JP5580774B2 (ja) 2014-08-27
PT1682907E (pt) 2012-02-03
EP1682907B1 (en) 2011-11-02
AU2004284496C1 (en) 2010-03-04
JP5789009B2 (ja) 2015-10-07
JP4840744B2 (ja) 2011-12-21
PL1682907T3 (pl) 2012-03-30
CY1116147T1 (el) 2017-02-08
EP1682907A1 (en) 2006-07-26
US20080193954A1 (en) 2008-08-14
ATE532073T1 (de) 2011-11-15
SI1682907T1 (sl) 2012-03-30
CY1112359T1 (el) 2015-12-09
JP2010279378A (ja) 2010-12-16
AU2004284496A1 (en) 2005-05-06
US20110104722A1 (en) 2011-05-05
AU2004284496B2 (en) 2009-08-06
CA2842308A1 (en) 2005-05-06
CA2542033A1 (en) 2005-05-06
US8084276B2 (en) 2011-12-27
EP2919012A1 (en) 2015-09-16
AU2009227844B2 (en) 2012-07-19
ES2530567T3 (es) 2015-03-03
ES2377012T3 (es) 2012-03-21
CN1879022A (zh) 2006-12-13
US20150037353A1 (en) 2015-02-05
CN102998458B (zh) 2015-07-22
JP2015171365A (ja) 2015-10-01
SI2317324T1 (sl) 2015-11-30
EP2317324B1 (en) 2014-11-12
CN1879022B (zh) 2012-10-17
EP1522857A1 (en) 2005-04-13
CN102998458A (zh) 2013-03-27
US20120220532A1 (en) 2012-08-30
EP2317324A1 (en) 2011-05-04
US20130189716A1 (en) 2013-07-25
JP2014115297A (ja) 2014-06-26
JP2011177184A (ja) 2011-09-15
PT2317324E (pt) 2015-02-17
HK1101426A1 (en) 2007-10-18
PL2317324T3 (pl) 2015-10-30
US7888137B2 (en) 2011-02-15
WO2005040817A1 (en) 2005-05-06

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