DK167813B1 - Pentapeptidderivat, farmaceutisk acceptable salte heraf, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat indeholdende et saadant derivat - Google Patents

Pentapeptidderivat, farmaceutisk acceptable salte heraf, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat indeholdende et saadant derivat Download PDF

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Publication number
DK167813B1
DK167813B1 DK615889A DK615889A DK167813B1 DK 167813 B1 DK167813 B1 DK 167813B1 DK 615889 A DK615889 A DK 615889A DK 615889 A DK615889 A DK 615889A DK 167813 B1 DK167813 B1 DK 167813B1
Authority
DK
Denmark
Prior art keywords
peptide
acm
glaucoma
eye
peptide derivative
Prior art date
Application number
DK615889A
Other languages
Danish (da)
English (en)
Other versions
DK615889A (da
DK615889D0 (da
Inventor
Fred Widmer
Kailash Kumar Gauri
Stig Aasmul-Olsen
Original Assignee
Carlbiotech Ltd As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Carlbiotech Ltd As filed Critical Carlbiotech Ltd As
Publication of DK615889D0 publication Critical patent/DK615889D0/da
Priority to DK615889A priority Critical patent/DK167813B1/da
Priority to PCT/DK1990/000322 priority patent/WO1991009053A1/en
Priority to HU921883A priority patent/HUT61322A/hu
Priority to US07/859,714 priority patent/US5411942A/en
Priority to EP91900187A priority patent/EP0504207B1/en
Priority to AT91900187T priority patent/ATE149517T1/de
Priority to KR1019920701341A priority patent/KR927003631A/ko
Priority to JP3500941A priority patent/JPH05504336A/ja
Priority to AU68989/91A priority patent/AU636427C/en
Priority to CA002069449A priority patent/CA2069449A1/en
Priority to DE69030100T priority patent/DE69030100D1/de
Publication of DK615889A publication Critical patent/DK615889A/da
Priority to NO92922229A priority patent/NO922229L/no
Priority to FI922620A priority patent/FI922620A0/fi
Priority to LVP-92-320A priority patent/LV10107B/en
Application granted granted Critical
Publication of DK167813B1 publication Critical patent/DK167813B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0819—Tripeptides with the first amino acid being acidic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
DK615889A 1989-12-07 1989-12-07 Pentapeptidderivat, farmaceutisk acceptable salte heraf, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat indeholdende et saadant derivat DK167813B1 (da)

Priority Applications (14)

Application Number Priority Date Filing Date Title
DK615889A DK167813B1 (da) 1989-12-07 1989-12-07 Pentapeptidderivat, farmaceutisk acceptable salte heraf, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat indeholdende et saadant derivat
KR1019920701341A KR927003631A (ko) 1989-12-07 1990-12-07 펩티드 유도체, 그 제조방법, 이를 함유한 제제 및 녹내장의 치료방법
AU68989/91A AU636427C (en) 1989-12-07 1990-12-07 Peptide derivative, process for the preparation thereof, pharmaceutical preparation containing it and method for treatment of glaucoma
US07/859,714 US5411942A (en) 1989-12-07 1990-12-07 Peptide derivative, pharmaceutical preparation containing it and method for treatment of glaucoma
EP91900187A EP0504207B1 (en) 1989-12-07 1990-12-07 Peptide derivative, process for the preparation thereof, pharmaceutical preparation containing it
AT91900187T ATE149517T1 (de) 1989-12-07 1990-12-07 Peptidderivat, verfahren zu dessen herstellung, sowie dieses enthaltende pharmazeutische zusammensetzung
PCT/DK1990/000322 WO1991009053A1 (en) 1989-12-07 1990-12-07 Peptide derivative, process for the preparation thereof, pharmaceutical preparation containing it and method for treatment of glaucoma
JP3500941A JPH05504336A (ja) 1989-12-07 1990-12-07 ペプチド誘導体，その製法，これを含む医薬品及び緑内障の治療法
HU921883A HUT61322A (en) 1989-12-07 1990-12-07 Process for producing peptide derivatives suitable for treating glaucoma and pharmaceutical compositions comprising same as active ingredient
CA002069449A CA2069449A1 (en) 1989-12-07 1990-12-07 Peptide derivative, process for the preparation thereof, pharmaceutical preparation containing it and method for treatment of glaucoma
DE69030100T DE69030100D1 (de) 1989-12-07 1990-12-07 Peptidderivat, verfahren zu dessen herstellung, sowie dieses enthaltende pharmazeutische zusammensetzung
NO92922229A NO922229L (no) 1989-12-07 1992-06-05 Peptid derivativ, fremgangsmaate til fremstilling av dissefarmasoeytiske preparater som inneholder disse og fremgangsmaate for behandling av glaucoma
FI922620A FI922620A0 (fi) 1989-12-07 1992-06-05 Peptidderivat, foerfarande foer dess framstaellning, ett farmaceutisk preparat innehaollande detta och foerfarande foer behandling av glaukoma.
LVP-92-320A LV10107B (en) 1989-12-07 1992-12-17 Peptide derivative, process for the preparation thereof, pharmaceutical preparation containing it and method for treatment of glaucome

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK615889A DK167813B1 (da) 1989-12-07 1989-12-07 Pentapeptidderivat, farmaceutisk acceptable salte heraf, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat indeholdende et saadant derivat
DK615889 1989-12-07

Publications (3)

Publication Number Publication Date
DK615889D0 DK615889D0 (da) 1989-12-07
DK615889A DK615889A (da) 1991-06-08
DK167813B1 true DK167813B1 (da) 1993-12-20

Family

ID=8147734

Family Applications (1)

Application Number Title Priority Date Filing Date
DK615889A DK167813B1 (da) 1989-12-07 1989-12-07 Pentapeptidderivat, farmaceutisk acceptable salte heraf, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat indeholdende et saadant derivat

Country Status (12)

Country Link
US (1) US5411942A (lv)
EP (1) EP0504207B1 (lv)
JP (1) JPH05504336A (lv)
KR (1) KR927003631A (lv)
AT (1) ATE149517T1 (lv)
CA (1) CA2069449A1 (lv)
DE (1) DE69030100D1 (lv)
DK (1) DK167813B1 (lv)
FI (1) FI922620A0 (lv)
HU (1) HUT61322A (lv)
LV (1) LV10107B (lv)
WO (1) WO1991009053A1 (lv)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5776892A (en) * 1990-12-21 1998-07-07 Curative Health Services, Inc. Anti-inflammatory peptides
DK53191D0 (da) * 1991-03-25 1991-03-25 Carlbiotech Ltd As Organosvovlforbindelse og farmaceutisk praeparat indeholdende en saadan forbindelse
DK53291D0 (da) * 1991-03-25 1991-03-25 Carlbiotech Ltd As Smaa peptider og peptidrelaterede stoffer samt farmaceutiske praeparater indeholdende saadanne forbindelser
US5968904A (en) * 1993-06-04 1999-10-19 Demegen, Inc. Modified arginine containing lytic peptides and method of making the same by glyoxylation
US5773413A (en) * 1993-06-04 1998-06-30 Demeter Biotechnologies, Ltd. Method of combating mammalian neoplasias, and lytic peptides therefor
US5561107A (en) * 1993-06-04 1996-10-01 Demeter Biotechnologies, Ltd. Method of enhancing wound healing by stimulating fibroblast and keratinocyte growth in vivo, utilizing amphipathic peptides
EP1961760A3 (en) * 1995-06-07 2008-09-03 Glaxo Group Limited Peptides and compounds that bind to a thrombopoietin receptor
US7091311B2 (en) 1996-06-07 2006-08-15 Smithkline Beecham Corporation Peptides and compounds that bind to a receptor
GB9818938D0 (en) * 1998-08-28 1998-10-21 Alpharma As Bioactive peptides
US8283315B2 (en) * 1998-08-28 2012-10-09 Lytix Biopharma As Inhibition of tumour growth
DK1542714T3 (da) 2002-09-18 2014-05-26 Janssen Pharmaceuticals Inc Fremgangsmåder til forøgelse af produktion af blodplader og hæmatopoietiske stamceller
US20040171554A1 (en) * 2003-02-07 2004-09-02 Genentech, Inc. Compositions and methods for enhancing apoptosis
US8076060B2 (en) * 2003-08-04 2011-12-13 Emil William Chynn Vaccination and immunotherapy as new therapeutic modalities in the treatment of glaucoma
CN102241742B (zh) * 2003-08-28 2014-04-02 奥索-麦克尼尔药品公司 结合血小板生成素受体的肽和化合物
US7723295B2 (en) * 2003-08-28 2010-05-25 Ortho-Mcneil Pharmaceutical, Inc. Peptides and compounds that bind to a receptor
AU2005228950B2 (en) * 2004-03-23 2012-02-02 Genentech, Inc. Azabicyclo-octane inhibitors of IAP
NZ549925A (en) 2004-04-07 2010-08-27 Novartis Ag Inhibitors of IAP
WO2006014361A1 (en) 2004-07-02 2006-02-09 Genentech, Inc. Inhibitors of iap
US20060210542A1 (en) * 2004-08-16 2006-09-21 Yurkow Edward J Use of TPO mimetic compounds and pharmaceutical compositions in the treatment of anemia
DE602005022936D1 (de) * 2004-12-20 2010-09-23 Genentech Inc Pyrrolidine als inhibitoren von iap
CN101374829A (zh) * 2005-12-19 2009-02-25 健泰科生物技术公司 Iap的抑制剂
PE20110217A1 (es) * 2006-08-02 2011-04-01 Novartis Ag DERIVADOS DE 2-OXO-ETIL-AMINO-PROPIONAMIDA-PIRROLIDIN-2-IL-SUSTITUIDOS COMO INHIBIDORES DEL ENLACE DE LA PROTEINA Smac AL INHIBIDOR DE LA PROTEINA DE APOPTOSIS
JP2010513561A (ja) * 2006-12-19 2010-04-30 ジェネンテック， インコーポレイテッド Ｉａｐのイミダゾピリジンインヒビター
PT2137655E (pt) * 2007-04-16 2012-09-14 Momenta Pharmaceuticals Inc Produtos de glicoproteína definidos e métodos relacionados
WO2008134679A1 (en) * 2007-04-30 2008-11-06 Genentech, Inc. Inhibitors of iap
CA2711606A1 (en) * 2008-01-11 2009-07-16 Genentech, Inc. Inhibitors of iap
CN102171209A (zh) 2008-08-02 2011-08-31 健泰科生物技术公司 Iap抑制剂
AU2009282978A1 (en) * 2008-08-16 2010-02-25 Genentech, Inc. Azaindole inhibitors of IAP
EP2556163B1 (en) 2010-04-07 2016-08-10 Momenta Pharmaceuticals, Inc. Method for quantifying high mannose containing glycoforms
CN103782168B (zh) 2011-03-12 2016-03-16 动量制药公司 在糖蛋白产品中包含n-乙酰己糖胺的n-聚醣
US9695244B2 (en) 2012-06-01 2017-07-04 Momenta Pharmaceuticals, Inc. Methods related to denosumab
WO2014149067A1 (en) 2013-03-15 2014-09-25 Momenta Pharmaceuticals, Inc. Methods related to ctla4-fc fusion proteins
ES2708759T3 (es) 2013-05-13 2019-04-11 Momenta Pharmaceuticals Inc Procedimientos para el tratamiento de la neurodegeneración
US20160257754A1 (en) 2013-10-16 2016-09-08 Momenta Pharmaceuticals Inc. Sialylated glycoproteins
JP2023518853A (ja) * 2020-03-25 2023-05-08 アウフバウ・メディカル・イノベイションズ・リミテッド 緑内障のためのプロセスおよび薬剤

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4457489A (en) * 1981-07-13 1984-07-03 Gilmore Samuel E Subsea fluid conduit connections for remote controlled valves
DE3360065D1 (en) * 1982-03-08 1985-03-28 Schering Corp Carboxyalkyl dipeptides, processes for their production and pharmaceutical compositions containing them
US4559340A (en) * 1983-11-25 1985-12-17 Schering Corporation Antihypertensive agents
US4634698A (en) * 1984-09-24 1987-01-06 Schering Corporation Antiglaucoma agents
EP0210204B1 (de) * 1985-01-18 1988-12-07 Kailash Kumar Dr. Prof. Gauri Proteinhydrolysate, verfahren zu ihrer herstellung und arzneimittel, die diese hydrolysate enthalten
IL86386A0 (en) * 1987-05-21 1988-11-15 Merrell Dow Pharma Novel anf derivatives
US4927807A (en) * 1987-10-06 1990-05-22 Abbott Laboratories Glaucoma treatment
GB8728560D0 (en) * 1987-12-07 1988-01-13 Glaxo Group Ltd Chemical compounds

Also Published As

Publication number Publication date
AU6898991A (en) 1991-07-18
FI922620A (fi) 1992-06-05
HUT61322A (en) 1992-12-28
KR927003631A (ko) 1992-12-18
LV10107B (en) 1995-02-20
HU9201883D0 (en) 1992-09-28
WO1991009053A1 (en) 1991-06-27
DK615889A (da) 1991-06-08
DE69030100D1 (de) 1997-04-10
FI922620A0 (fi) 1992-06-05
EP0504207A1 (en) 1992-09-23
EP0504207B1 (en) 1997-03-05
LV10107A (lv) 1994-05-10
ATE149517T1 (de) 1997-03-15
US5411942A (en) 1995-05-02
DK615889D0 (da) 1989-12-07
CA2069449A1 (en) 1991-06-08
AU636427B2 (en) 1993-04-29
JPH05504336A (ja) 1993-07-08

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed