DK166388C - Krystallinsk 7-(r)-amino-3-(1-pyridiniummethyl)-ceph-3-em-4-carboxylat-monohydrochlorid-monohydrat og fremgangsmaade til fremstilling heraf - Google Patents

Krystallinsk 7-(r)-amino-3-(1-pyridiniummethyl)-ceph-3-em-4-carboxylat-monohydrochlorid-monohydrat og fremgangsmaade til fremstilling heraf

Info

Publication number
DK166388C
DK166388C DK297284A DK297284A DK166388C DK 166388 C DK166388 C DK 166388C DK 297284 A DK297284 A DK 297284A DK 297284 A DK297284 A DK 297284A DK 166388 C DK166388 C DK 166388C
Authority
DK
Denmark
Prior art keywords
mono
crystallinic
ceph
amino
preparing
Prior art date
Application number
DK297284A
Other languages
English (en)
Other versions
DK297284D0 (da
DK297284A (da
DK166388B (da
Inventor
Preston Charles Conrad
Alvydas Alfonsas Jarmas
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of DK297284D0 publication Critical patent/DK297284D0/da
Publication of DK297284A publication Critical patent/DK297284A/da
Publication of DK166388B publication Critical patent/DK166388B/da
Application granted granted Critical
Publication of DK166388C publication Critical patent/DK166388C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/247-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/247-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/187-Aminocephalosporanic or substituted 7-aminocephalosporanic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
DK297284A 1983-06-20 1984-06-18 Krystallinsk 7-(r)-amino-3-(1-pyridiniummethyl)-ceph-3-em-4-carboxylat-monohydrochlorid-monohydrat og fremgangsmaade til fremstilling heraf DK166388C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US50566283 1983-06-20
US06/505,662 US4540779A (en) 1983-06-20 1983-06-20 Crystalline 7-(R)-amino-3-(1'pyridiniummethyl)-ceph-3-em-4-carboxylate monohydrochloride monohydrate compound

Publications (4)

Publication Number Publication Date
DK297284D0 DK297284D0 (da) 1984-06-18
DK297284A DK297284A (da) 1984-12-21
DK166388B DK166388B (da) 1993-05-10
DK166388C true DK166388C (da) 1993-09-27

Family

ID=24011278

Family Applications (1)

Application Number Title Priority Date Filing Date
DK297284A DK166388C (da) 1983-06-20 1984-06-18 Krystallinsk 7-(r)-amino-3-(1-pyridiniummethyl)-ceph-3-em-4-carboxylat-monohydrochlorid-monohydrat og fremgangsmaade til fremstilling heraf

Country Status (12)

Country Link
US (1) US4540779A (da)
EP (1) EP0135258B1 (da)
JP (1) JPS6013793A (da)
KR (1) KR870000327B1 (da)
CA (1) CA1216577A (da)
DE (1) DE3479659D1 (da)
DK (1) DK166388C (da)
GB (1) GB2141715B (da)
GR (1) GR82375B (da)
HU (1) HU192558B (da)
IE (1) IE57622B1 (da)
IL (1) IL72103A (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60169486A (ja) * 1984-02-10 1985-09-02 Yamanouchi Pharmaceut Co Ltd 7−アミノ−3−置換メチル−3−セフエム−4−カルボン酸およびその低級アルキルシリル誘導体の製造法
US4959469A (en) * 1984-12-27 1990-09-25 Banyu Pharmaceutical Company, Ltd. Crystalline cephalosporin compounds
JPH0649707B2 (ja) * 1985-03-01 1994-06-29 第一製薬株式会社 3−ピリジニウムメチルセフエム誘導体
US4714760A (en) * 1985-08-20 1987-12-22 Bristol-Myers Company Cephalosporin intermediates
US4692518A (en) * 1985-11-06 1987-09-08 Eli Lilly And Company Crystalline (7R)-7-amino-3-(1'-pyridiniummethyl)-3-cephem-4-carboxylate monohydrate compound
DE10155242A1 (de) * 2001-11-09 2003-05-22 Bayer Ag Herstellung von Polyamid
CN109134499A (zh) * 2018-10-10 2019-01-04 河北鸿旭翔药业有限公司 7-氨基-3-(1-吡啶甲基)头孢烯酸氯化物及其制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB953695A (en) * 1959-08-04 1964-03-25 Nat Res Dev Derivatives of cephalosporin c
AR229883A1 (es) * 1978-05-26 1983-12-30 Glaxo Group Ltd Procedimiento para la preparacion de antibiotico(6r,7r)-7-((z)-2-(2-aminotiazol-4-il)-2-(2-carboxiprop-2-oxiimino)-acetamido)-3-(1-piridinometil)-cef-3-em-4-carboxilato
BE883453A (fr) * 1979-05-25 1980-11-24 Glaxo Group Ltd Composes intermediaires pour la preparation de cephalosporines

Also Published As

Publication number Publication date
KR850000459A (ko) 1985-02-27
US4540779A (en) 1985-09-10
HU192558B (en) 1987-06-29
IE57622B1 (en) 1993-02-10
EP0135258A2 (en) 1985-03-27
DK297284D0 (da) 1984-06-18
IL72103A0 (en) 1984-10-31
GR82375B (da) 1984-12-13
GB2141715B (en) 1986-12-10
HUT34756A (en) 1985-04-28
GB8415508D0 (en) 1984-07-25
JPS6013793A (ja) 1985-01-24
KR870000327B1 (ko) 1987-02-27
IE841505L (en) 1984-12-20
CA1216577A (en) 1987-01-13
DK297284A (da) 1984-12-21
EP0135258B1 (en) 1989-09-06
IL72103A (en) 1987-12-20
DK166388B (da) 1993-05-10
GB2141715A (en) 1985-01-03
EP0135258A3 (en) 1985-12-18
DE3479659D1 (en) 1989-10-12

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