DK1663168T3 - Nikotinformuleringer og anvendelse deraf - Google Patents

Nikotinformuleringer og anvendelse deraf

Info

Publication number
DK1663168T3
DK1663168T3 DK04769203T DK04769203T DK1663168T3 DK 1663168 T3 DK1663168 T3 DK 1663168T3 DK 04769203 T DK04769203 T DK 04769203T DK 04769203 T DK04769203 T DK 04769203T DK 1663168 T3 DK1663168 T3 DK 1663168T3
Authority
DK
Denmark
Prior art keywords
nicotine
nicotine formulations
cellulose
formulations
algae
Prior art date
Application number
DK04769203T
Other languages
Danish (da)
English (en)
Inventor
Bo Ragnar Ek
Sven-Boerje Andersson
Bengt Ake Bosson
Nils-Olof Lindberg
Albert Mihranyan
Original Assignee
Mcneil Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34277854&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1663168(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from SE0302387A external-priority patent/SE0302387D0/xx
Application filed by Mcneil Ab filed Critical Mcneil Ab
Application granted granted Critical
Publication of DK1663168T3 publication Critical patent/DK1663168T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/465Nicotine; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A61K9/0058Chewing gums
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
DK04769203T 2003-09-08 2004-08-27 Nikotinformuleringer og anvendelse deraf DK1663168T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US50106103P 2003-09-08 2003-09-08
SE0302387A SE0302387D0 (sv) 2003-09-08 2003-09-08 Nicotine formulations and use thereof
PCT/IB2004/002787 WO2005023227A2 (en) 2003-09-08 2004-08-27 Nicotine formulations and use thereof

Publications (1)

Publication Number Publication Date
DK1663168T3 true DK1663168T3 (da) 2009-06-08

Family

ID=34277854

Family Applications (1)

Application Number Title Priority Date Filing Date
DK04769203T DK1663168T3 (da) 2003-09-08 2004-08-27 Nikotinformuleringer og anvendelse deraf

Country Status (13)

Country Link
US (1) US20050053665A1 (es)
EP (1) EP1663168B1 (es)
JP (1) JP4604034B2 (es)
AT (1) ATE422355T1 (es)
AU (1) AU2004269986A1 (es)
BR (1) BRPI0414196A (es)
CA (1) CA2537488A1 (es)
DE (1) DE602004019430D1 (es)
DK (1) DK1663168T3 (es)
ES (1) ES2321721T3 (es)
MX (1) MXPA06002609A (es)
PL (1) PL1663168T3 (es)
WO (1) WO2005023227A2 (es)

Families Citing this family (75)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2383296A1 (fr) * 2002-05-10 2003-11-10 Ginette Godbout Composition pour l'amelioration de la sante et de la structure des ongles, methode d'utilisation
KR20050096922A (ko) 2002-12-20 2005-10-06 니코노범 에이비 물리적 및 화학적으로 안정된 니코틴 함유 입자물질
JP5283334B2 (ja) 2003-01-24 2013-09-04 マグル ホールディング エービー 経粘膜伝達用組成物材料
EP1691631A4 (en) 2003-11-07 2012-09-05 Us Smokeless Tobacco Co TOBACCO COMPOSITIONS
US8627828B2 (en) 2003-11-07 2014-01-14 U.S. Smokeless Tobacco Company Llc Tobacco compositions
DE10356925B4 (de) * 2003-12-05 2006-05-11 Lts Lohmann Therapie-Systeme Ag Inhalator für basische pharmazeutische Wirkstoffe sowie Verfahren für dessen Herstellung
EP1802258A4 (en) 2004-09-13 2015-09-23 Chrono Therapeutics Inc BIOSYNCHRONE TRANSDERMAL MEDICINES
US8252321B2 (en) 2004-09-13 2012-08-28 Chrono Therapeutics, Inc. Biosynchronous transdermal drug delivery for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and the treatment of hyperglycemia, alzheimer's disease, sleep disorders, parkinson's disease, aids, epilepsy, attention deficit disorder, nicotine addiction, cancer, headache and pain control, asthma, angina, hypertension, depression, cold, flu and the like
US20060240084A1 (en) * 2005-04-20 2006-10-26 Xylos Corporation Microbial cellulose materials for use in transdermal drug delivery systems, method of manufacture and use
JP5255449B2 (ja) * 2005-12-06 2013-08-07 エフ エム シー コーポレーション セルロースゲル配合物
CA2657932A1 (en) * 2006-03-16 2007-09-20 Niconovum Ab Stable lozenge compositions providing rapid release of nicotine
AU2007224584A1 (en) * 2006-03-16 2007-09-20 Niconovum Ab Improved snuff composition
CA2682432C (en) * 2007-03-30 2017-06-06 Duke University Device and method for delivery of a medicament
GB2468424B (en) * 2007-04-02 2011-11-09 Parkinson S Inst Methods and compositions for reduction of side effects of therapeutic treatments
GB2448224B (en) * 2007-04-02 2010-09-01 Parkinson S Inst Solid orally administered pharmaceutical composition for the reduction of side-effects of a dopaminergic agent
US20080286341A1 (en) * 2007-05-16 2008-11-20 Sven-Borje Andersson Buffered coated nicotine containing products
US20080286340A1 (en) * 2007-05-16 2008-11-20 Sven-Borje Andersson Buffered nicotine containing products
EP2197430A2 (en) * 2007-09-18 2010-06-23 NicoNovum AB Stable chewing gum compositions comprising maltitol and providing rapid release of nicotine
AU2008334684A1 (en) * 2007-12-11 2009-06-18 Novartis Ag Multi-zone films
WO2009079078A1 (en) 2007-12-14 2009-06-25 Labogroup S.A.S. Delivering aerosolizable food products
CL2009001025A1 (es) 2008-05-01 2010-09-24 Smithkline Beecham Corp Composicion de pastilla para chupar que comprende: a) un granulo patron con al menos: un agente tampon alcalino, un modificador de la disolucion y una carga, b) un principio activo de nicotina definido extragranular y al menos un agente tampon alcalino; procedimiento de preparacion; util para eliminar o reducir el uso de tabaco.
EP2293786B1 (en) * 2008-05-21 2014-11-26 Novartis AG Tablettable chewing gums comprising nicotine and a buffering agent
US8747005B2 (en) * 2008-06-04 2014-06-10 Colgate-Palmolive Company Oral care implement with cavitation system
WO2010014506A2 (en) * 2008-07-28 2010-02-04 R.J. Reynolds Tobacco Company Smokeless tobacco products and processes
US20100018541A1 (en) * 2008-07-28 2010-01-28 Anthony Richard Gerardi Smokeless tobacco products and processes
WO2010031552A1 (en) * 2008-09-17 2010-03-25 Niconovum Ab Process for preparing snuff composition
US8506936B2 (en) * 2008-11-25 2013-08-13 Watson Laboratories, Inc. Stabilized nicotine chewing gum
NO2405942T3 (es) 2009-03-13 2018-03-31
AU2010226152B2 (en) 2009-03-17 2014-09-25 Philip Morris Products Sa Tobacco-based nicotine aerosol generation system
US8551235B2 (en) 2009-04-23 2013-10-08 Green Wave Innovative Solutions, Llc Algae based fire resistant materials and method of making same
JP5732043B2 (ja) * 2009-04-24 2015-06-10 オムヤ インターナショナル アーゲー 活性成分を放出制御するための粒状物質
CA2774264C (en) 2009-09-16 2014-09-23 Philip Morris Products S.A. Improved device and method for delivery of a medicament
BR112012020731A2 (pt) * 2010-02-18 2016-04-26 Jatin Vasant Thakkar pastilhas gelatinosas suaves com nicotina.
US20110268809A1 (en) 2010-04-28 2011-11-03 Paul Andrew Brinkley Nicotine-Containing Pharmaceutical Compositions
US20110274628A1 (en) 2010-05-07 2011-11-10 Borschke August J Nicotine-containing pharmaceutical compositions
SE535587C2 (sv) 2011-03-29 2012-10-02 Chill Of Sweden Ab Produkt innehållande ett fritt nikotinsalt och en ej vattenlöslig påse
US20130017259A1 (en) 2011-07-06 2013-01-17 The Parkinson's Institute Compositions and Methods for Treatment of Symptoms in Parkinson's Disease Patients
US9084439B2 (en) 2011-09-22 2015-07-21 R.J. Reynolds Tobacco Company Translucent smokeless tobacco product
US20130078307A1 (en) 2011-09-22 2013-03-28 Niconovum Usa, Inc. Nicotine-containing pharmaceutical composition
US9629392B2 (en) 2011-09-22 2017-04-25 R.J. Reynolds Tobacco Company Translucent smokeless tobacco product
US9474303B2 (en) 2011-09-22 2016-10-25 R.J. Reynolds Tobacco Company Translucent smokeless tobacco product
US9907748B2 (en) 2011-10-21 2018-03-06 Niconovum Usa, Inc. Excipients for nicotine-containing therapeutic compositions
CN102754908B (zh) 2012-01-20 2015-06-10 奥驰亚客户服务公司 口腔用烟草产品
US9854831B2 (en) 2012-01-20 2018-01-02 Altria Client Services Llc Oral product
CN103039688B (zh) 2012-01-20 2016-01-06 奥驰亚客户服务公司 口腔用产品
CN102754907B (zh) * 2012-01-20 2015-06-24 奥驰亚客户服务公司 口腔用产品
US9763928B2 (en) 2012-02-10 2017-09-19 Niconovum Usa, Inc. Multi-layer nicotine-containing pharmaceutical composition
US20140255452A1 (en) 2013-03-11 2014-09-11 Niconovum Usa, Inc. Method and apparatus for differentiating oral pouch products
US9521864B2 (en) * 2013-07-19 2016-12-20 Altria Client Services Llc Methods and systems for incorporating nicotine into oral products
US11779045B2 (en) 2013-10-03 2023-10-10 Altria Client Services Llc Dissolvable-chewable exhausted-tobacco tablet
US10105320B2 (en) 2013-10-03 2018-10-23 Altria Client Services Soluble fiber lozenge
US9351936B2 (en) 2013-10-03 2016-05-31 Altria Client Services Llc Nicotine lozenge
US10244786B2 (en) 2013-10-03 2019-04-02 Altria Client Services Llc Tobacco lozenge
US9999243B2 (en) 2013-10-03 2018-06-19 Altria Client Services Llc Exhausted tobacco lozenge
GB201411526D0 (en) * 2014-06-27 2014-08-13 British American Tobacco Co Powder
US10213586B2 (en) 2015-01-28 2019-02-26 Chrono Therapeutics Inc. Drug delivery methods and systems
AU2016228779A1 (en) 2015-03-12 2017-09-07 Chrono Therapeutics Inc. Craving input and support system
US20170165252A1 (en) 2015-12-10 2017-06-15 Niconovum Usa Inc. Protein-enriched therapeutic composition
GB201602579D0 (en) * 2016-02-12 2016-03-30 Mihranyan Albert New compositions
NZ744942A (en) * 2016-04-12 2020-08-28 Herrera Arturo Solis Compositions and methods for treating nasal and paranasal mucosa diseases with nicotinic acetylcholine receptor agonists
ES2834064T3 (es) * 2016-12-30 2021-06-16 Philip Morris Products Sa Lámina que contiene nicotina
WO2018129304A1 (en) 2017-01-06 2018-07-12 Chrono Therapeutics Inc. Transdermal drug delivery devices and methods
GB201714412D0 (en) * 2017-09-07 2017-10-25 Emplicure Ab Evaporation devices containing plant material
AU2019279884A1 (en) 2018-05-29 2020-12-10 Morningside Venture Investments Limited Drug delivery methods and systems
BR112020025604A2 (pt) * 2018-06-15 2021-03-23 R.J. Reynolds Tobacco Company purificação de nicotina
BR112020024276A2 (pt) * 2018-06-28 2021-02-23 Philip Morris Products S.A. cartucho para um sistema gerador de aerossol contendo uma fonte de nicotina compreendendo uma formulação de nicotina líquida
US11395507B2 (en) 2018-09-07 2022-07-26 Altria Client Services Llc Filter for an e-vaping device, e-vaping device with the filter, and method of forming the filter
US11432581B2 (en) * 2018-09-07 2022-09-06 Altria Client Services Llc Capsule containing a matrix, device with the matrix, and method of forming the matrix
US11311048B2 (en) 2018-09-07 2022-04-26 Altria Client Services Llc E-vaping device with an insert
PL3809884T3 (pl) 2019-06-07 2023-01-09 Philip Morris Products S.A. Woreczkowy produkt nikotynowy
DK180339B1 (en) * 2019-06-07 2020-12-18 Ncp Nextgen As Nicotine pouch composition and pouch comprising such
DK3833315T3 (da) * 2019-10-04 2022-12-05 Schjoelin Evaggelos Poseprodukt der er egnet til anvendelse i en mundhule
EP4014759A1 (en) 2020-12-18 2022-06-22 VIRAofSWEDEN AB Novel product comprising brown alga extract
EP4094594A1 (en) 2021-05-25 2022-11-30 Consumer Brands International s.r.o. A filing of a nicotine formulation, in particular a nicotine sachet and the method of its manufacture, and a mixture of nicotine salts and the method of its manufacture
WO2023187225A1 (en) 2022-04-01 2023-10-05 Amplicon Ab Alkaline intraoral products

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US59939A (en) * 1866-11-27 Chakles e
US2002218A (en) * 1934-08-22 1935-05-21 Bell Telephone Labor Inc Tie trunk line
DE1517264C3 (de) * 1963-10-31 1978-09-07 Celanese Corp., New York, N.Y. (V.St.A.) Tabakfreies Tabakaustauschmaterial
GB1362611A (en) * 1972-03-14 1974-08-07 Ici Ltd Smoking mixtures
US4748181A (en) * 1979-08-28 1988-05-31 Foundation For Behavioral Research Method for treating hypertension with nicotine
GB8301659D0 (en) * 1983-01-21 1983-02-23 Leo Ab Smoking substitutes
US4735218A (en) * 1984-09-09 1988-04-05 Kondo Akiko Tobacco filter
GB8615676D0 (en) * 1986-06-26 1986-07-30 Stoppers Co Ltd Nicotine containing lozenge
GB8804164D0 (en) * 1988-02-23 1988-03-23 Tucker J M Bandage for administering physiologically active compound
US5824334A (en) * 1989-09-05 1998-10-20 University Of Utah Research Foundation Tobacco substitute
US5167242A (en) * 1990-06-08 1992-12-01 Kabi Pharmacia Aktiebolaq Nicotine-impermeable container and method of fabricating the same
US5135753A (en) * 1991-03-12 1992-08-04 Pharmetrix Corporation Method and therapeutic system for smoking cessation
US6024097A (en) * 1992-02-20 2000-02-15 J Mom Trust Product for assisting a smoker in giving up the habit
US5362496A (en) * 1993-08-04 1994-11-08 Pharmetrix Corporation Method and therapeutic system for smoking cessation
SE9303574D0 (sv) * 1993-11-01 1993-11-01 Kabi Pharmacia Ab Composition for drug delivery and method the manufacturing thereof
US5810018A (en) * 1994-12-29 1998-09-22 Monte; Woodrow C. Method, composition and apparatus for reducing the incidence of cigarette smoking
JP3687194B2 (ja) * 1996-06-06 2005-08-24 味の素株式会社 水不溶性グルカンの精製方法
AU2660599A (en) * 1998-02-06 1999-08-23 Monsanto Company Acid-stable and cationic-compatible cellulose compositions and methods of preparation
US6583160B2 (en) * 1999-04-14 2003-06-24 Steve Smith Nicotine therapy method and oral carrier for assuaging tobacco-addiction
KR20050096922A (ko) * 2002-12-20 2005-10-06 니코노범 에이비 물리적 및 화학적으로 안정된 니코틴 함유 입자물질
JP5283334B2 (ja) * 2003-01-24 2013-09-04 マグル ホールディング エービー 経粘膜伝達用組成物材料

Also Published As

Publication number Publication date
MXPA06002609A (es) 2006-06-05
EP1663168B1 (en) 2009-02-11
BRPI0414196A (pt) 2006-10-31
ATE422355T1 (de) 2009-02-15
ES2321721T3 (es) 2009-06-10
CA2537488A1 (en) 2005-03-17
US20050053665A1 (en) 2005-03-10
EP1663168A2 (en) 2006-06-07
JP2007505037A (ja) 2007-03-08
WO2005023227A2 (en) 2005-03-17
WO2005023227A3 (en) 2005-06-16
DE602004019430D1 (de) 2009-03-26
JP4604034B2 (ja) 2010-12-22
AU2004269986A1 (en) 2005-03-17
PL1663168T3 (pl) 2009-07-31

Similar Documents

Publication Publication Date Title
DK1663168T3 (da) Nikotinformuleringer og anvendelse deraf
WO2006086562A3 (en) Phenylazetidinone derivatives
DK1753440T3 (da) Oral administrationsform indeholdende probiotiske bakterier
DE60327438D1 (de) Amino-substituierte cyclohexan derivate zur behandlung bakterieller infektionen
EA200870019A1 (ru) Лактамовые соединения и способы их применения
ATE509917T1 (de) Gamma-secretase-inhibitoren
MY142589A (en) Benzimidazole derivatives : preparation and pharmaceutical applications
PL1654253T3 (pl) Podstawione pochodne 3-pirolidynoindolu
CO5660287A2 (es) Derivados de tetrahidrocarbazol y su uso farmaceutico
TW200510325A (en) 2-acylamino-4-phenylthiazole derivatives, preparation thereof and therapeutic application thereof
EA200600280A1 (ru) Композиции на основе производных липопептидных антибиотиков и способы их применения
WO2008039829A3 (en) Diphenylheterocycle cholesterol absorption inhibitors
WO2005018605A3 (en) Novel formulation of ropinirole
NO20063619L (no) Diarylmetylpiperazinderivater, fremstilling og anvendelse derav
ECSP088510A (es) Combinación fungicida de principios activos
WO2004091591A3 (fr) Composition nutritionnelle ou therapeutique contenant le compose oleurofeine ou l'un de ses derives
ATE509018T1 (de) Als antimikrobielle mittel geeignete bisindolpyrrole
DE602005021095D1 (de) Antimikrobielle zusammensetzungen und ihre verwendungen
DE60131968D1 (de) PYRANOÄ2,3-cÜIMIDAZOÄ1,2-aÜPYRIDIN-DERIVATE ZUR BEHANDLUNG VON GASTROINTESTINALEN ERKRANKUNGEN
TW200509794A (en) Novel anthelmintic and insecticidal compositions
AU2006272424A8 (en) Homogemcitabines
TW200603791A (en) Compounds and compositions as cathepsin S inhibitors
NO20063617L (no) Diarylmetylidenpiperidinderivater, fremstilling og anvendelse derav
NO20063618L (no) Diarylmetylpiperidinderivater, fremstilling og anvendelse derav
WO2004019865A3 (en) Amelioration of effects of cigarette smoke