DK165749C - Grf-analoge peptider og farmaceutisk acceptable salte heraf samt farmaceutisk middel indeholdende disse - Google Patents

Grf-analoge peptider og farmaceutisk acceptable salte heraf samt farmaceutisk middel indeholdende disse

Info

Publication number
DK165749C
DK165749C DK433684A DK433684A DK165749C DK 165749 C DK165749 C DK 165749C DK 433684 A DK433684 A DK 433684A DK 433684 A DK433684 A DK 433684A DK 165749 C DK165749 C DK 165749C
Authority
DK
Denmark
Prior art keywords
pharmaceutical
acceptable salts
substances containing
analogue peptides
grf analogue
Prior art date
Application number
DK433684A
Other languages
Danish (da)
English (en)
Other versions
DK165749B (da
DK433684A (da
DK433684D0 (da
Inventor
Jean Edouard Frederic Rivier
Jr Wylie Walker Vale
Original Assignee
Salk Inst For Biological Studi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Salk Inst For Biological Studi filed Critical Salk Inst For Biological Studi
Publication of DK433684D0 publication Critical patent/DK433684D0/da
Publication of DK433684A publication Critical patent/DK433684A/da
Publication of DK165749B publication Critical patent/DK165749B/da
Application granted granted Critical
Publication of DK165749C publication Critical patent/DK165749C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/60—Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/142—Amino acids; Derivatives thereof
    • A23K20/147—Polymeric derivatives, e.g. peptides or proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/12—Growth hormone, growth factor other than t-cell or b-cell growth factor, and growth hormone releasing factor; related peptides

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Polymers & Plastics (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Husbandry (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK433684A 1983-09-13 1984-09-11 Grf-analoge peptider og farmaceutisk acceptable salte heraf samt farmaceutisk middel indeholdende disse DK165749C (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US53217083A 1983-09-13 1983-09-13
US53217083 1983-09-13
US06/545,094 US4518586A (en) 1983-01-13 1983-10-25 GRF Analogs III
US54509483 1983-10-25

Publications (4)

Publication Number Publication Date
DK433684D0 DK433684D0 (da) 1984-09-11
DK433684A DK433684A (da) 1985-03-14
DK165749B DK165749B (da) 1993-01-11
DK165749C true DK165749C (da) 1993-06-14

Family

ID=27063766

Family Applications (1)

Application Number Title Priority Date Filing Date
DK433684A DK165749C (da) 1983-09-13 1984-09-11 Grf-analoge peptider og farmaceutisk acceptable salte heraf samt farmaceutisk middel indeholdende disse

Country Status (21)

Country Link
US (1) US4518586A (es)
EP (1) EP0146210B1 (es)
JP (1) JPH0689035B2 (es)
AU (1) AU577057B2 (es)
CA (1) CA1271599A (es)
DE (1) DE3462603D1 (es)
DK (1) DK165749C (es)
ES (1) ES535846A0 (es)
FI (1) FI88402C (es)
GR (1) GR80335B (es)
HU (1) HU200192B (es)
IE (1) IE57774B1 (es)
IL (1) IL72799A (es)
IN (1) IN160247B (es)
MX (1) MX161018A (es)
NO (1) NO166944C (es)
NZ (1) NZ209515A (es)
PH (1) PH22310A (es)
PT (1) PT79189B (es)
SU (1) SU1435157A3 (es)
YU (1) YU45968B (es)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4728726A (en) * 1982-10-04 1988-03-01 The Salk Institute For Biological Studies GRF analogs IIIb
AU575843B2 (en) * 1983-08-10 1988-08-11 The Administrators Of The Tulane Eductional Fund Growth hormone releasing peptides
US4626523A (en) * 1983-09-13 1986-12-02 The Salk Institute For Biological Studies GRF analogs II
US4617149A (en) * 1983-09-21 1986-10-14 Eli Lilly And Company Growth hormone release factor analogs
US4528190A (en) * 1983-10-25 1985-07-09 The Salk Institute For Biological Studies GRF Analogs IV
US4649131A (en) * 1984-09-24 1987-03-10 Hoffmann-La Roche Inc. Growth hormone releasing factor analogs
CA1271600A (en) * 1985-01-07 1990-07-10 David Howard Coy Growth hormone-releasing peptides and method of treating mammals therewith
EP0193910A3 (en) * 1985-03-06 1988-11-23 Sumitomo Pharmaceuticals Company, Limited Synthesis of a derivative of grf and intermediate peptides
US4734399A (en) * 1985-08-06 1988-03-29 Hoffmann-La Roche Inc. Growth hormone releasing factor analogs
EP0212531A1 (en) * 1985-08-12 1987-03-04 Syntex (U.S.A.) Inc. Bovine growth hormone releasing factor derivative
US4689318A (en) * 1985-08-29 1987-08-25 The Salk Institute For Biological Studies GRF analogs
US4870054A (en) * 1985-09-27 1989-09-26 Recker Robert R Treatment for osteoporosis using GRF or a biologically active analog thereof
US4880778A (en) * 1986-05-12 1989-11-14 Eastman Kodak Company Combinations having synergistic growth hormone releasing activity and methods for use thereof
IL84758A (en) * 1987-01-13 1992-03-29 Salk Inst For Biological Studi Peptides stimulating the release of pituitary growth hormone in fish and amphibians,and pharmaceutical compositions containing them
IL86102A (en) * 1987-05-11 1994-04-12 Univ Tulane Alkylated peptides that release growth hormone and their use
US5002931A (en) * 1987-05-22 1991-03-26 The Salk Institute For Biological Studies GRF analogs VII
US4839344A (en) * 1987-06-12 1989-06-13 Eastman Kodak Company Polypeptide compounds having growth hormone releasing activity
USRE33699E (en) * 1987-07-09 1991-09-24 International Minerals & Chemical Corp. Growth hormone-releasing factor analogs
US4801456A (en) * 1987-07-09 1989-01-31 International Minerals & Chemical Corp. Growth hormone-releasing factor analogs
US4880777A (en) * 1987-09-01 1989-11-14 Eastman Kodak Company Synthetic peptides having growth hormone releasing activity
EP0400051B1 (en) * 1988-01-28 1995-05-10 Polygen Holding Corporation Polypeptide compounds having growth hormone releasing activity
US5043322A (en) * 1988-07-22 1991-08-27 The Salk Institute For Biological Studies Cyclic GRF analogs
US5023322A (en) * 1988-08-31 1991-06-11 Mta Kutatas-Es Szervezetelemzo Intezete Analogs of growth hormone releasing factor (GRF) and a method for the preparation thereof
US5756458A (en) * 1989-06-16 1998-05-26 Pharmacia & Upjohn Company Stabilized potent GRF analogs
CA2085362A1 (en) * 1990-06-29 1991-12-30 Arthur M. Felix Histidine substituted growth hormone releasing factor analogs
ATE119916T1 (de) * 1990-12-10 1995-04-15 Hoffmann La Roche Verfahren zur enzymatischen herstellung von grf(1-44)nh2.
JPH05507939A (ja) * 1991-04-09 1993-11-11 エフ・ホフマン―ラ　ロシユ　アーゲー 成長ホルモン放出因子の類似体
US5246920A (en) * 1992-06-15 1993-09-21 University Of South Florida Treatment of hyperprolactinemia
US5811074A (en) * 1992-06-29 1998-09-22 University Of South Florida Method of diagnosing pituitary dependent growth hormone deficiency
US5550212A (en) * 1993-12-17 1996-08-27 The Administrators Of The Tulane Educational Fund Analogues of hGH-RH(1-29)NH2 having antagonistic activity
EP1355941A2 (en) * 2001-02-02 2003-10-29 ConjuChem, Inc. Long lasting growth hormone releasing factor derivatives
NZ539218A (en) * 2002-09-18 2008-03-28 Univ Montreal Ct Hospitalier Chum Synthetic GHRH analogues of 29 amino acids or more
PT2118123E (pt) 2007-01-31 2016-02-10 Harvard College Péptidos de p53 estabilizados e suas utilizações
ES2430067T3 (es) 2007-03-28 2013-11-18 President And Fellows Of Harvard College Polipéptidos cosidos
WO2009009727A2 (en) * 2007-07-12 2009-01-15 Akela Pharma Srl Ghrh analogs and therapeutic uses thereof
WO2012021874A1 (en) 2010-08-13 2012-02-16 Aileron Therapeutics, Inc. Peptidomimetic macrocycles with thioether linkers
MX2013012259A (es) 2011-04-21 2013-11-22 Theratechnologies Inc Analogos del factor de liberacion de la hormona de crecimiento (grf) y usos de estos.
BR112014009418A2 (pt) 2011-10-18 2017-04-18 Aileron Therapeutics Inc macrociclos peptidomiméticos
EP2819688A4 (en) 2012-02-15 2015-10-28 Aileron Therapeutics Inc TRIAZOL AND THIOETHER-COUPLED PEPTIDOMIMETIC MACROCYCLES
AU2013221432B2 (en) 2012-02-15 2018-01-18 Aileron Therapeutics, Inc. Peptidomimetic macrocycles
JP6526563B2 (ja) 2012-11-01 2019-06-05 エイルロン セラピューティクス，インコーポレイテッド 二置換アミノ酸ならびにその調製および使用の方法
CA2961258A1 (en) 2014-09-24 2016-03-31 Aileron Therapeutics, Inc. Peptidomimetic macrocycles and uses thereof
CN107614003A (zh) 2015-03-20 2018-01-19 艾瑞朗医疗公司 拟肽大环化合物及其用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ204456A (en) * 1982-06-16 1987-05-29 Salk Inst For Biological Studi Synthetic pancreatic growth-hormone releasing factor
IL70530A (en) * 1983-01-13 1986-09-30 Salk Inst For Biological Studi Synthetic peptides having growth hormone releasing factor activity and compositions containing them
DE3482387D1 (en) * 1983-03-07 1990-07-05 Hoffmann La Roche Polypeptide.
AU575843B2 (en) * 1983-08-10 1988-08-11 The Administrators Of The Tulane Eductional Fund Growth hormone releasing peptides
PT79094B (en) * 1983-08-29 1986-08-14 Salk Inst For Biological Studi Grf analogs

Also Published As

Publication number Publication date
DK165749B (da) 1993-01-11
US4518586A (en) 1985-05-21
IE57774B1 (en) 1993-04-07
EP0146210B1 (en) 1987-03-11
HU200192B (en) 1990-04-28
NZ209515A (en) 1988-08-30
EP0146210A1 (en) 1985-06-26
CA1271599A (en) 1990-07-10
ES8600217A1 (es) 1985-10-01
JPH0689035B2 (ja) 1994-11-09
MX161018A (es) 1990-07-05
DE3462603D1 (en) 1987-04-16
IL72799A0 (en) 1984-11-30
AU3259484A (en) 1985-03-21
FI88402B (fi) 1993-01-29
ES535846A0 (es) 1985-10-01
PH22310A (en) 1988-07-22
IL72799A (en) 1987-10-30
HUT35696A (en) 1985-07-29
IN160247B (es) 1987-07-04
FI843579A0 (fi) 1984-09-12
DK433684A (da) 1985-03-14
FI88402C (fi) 1993-05-10
FI843579L (fi) 1985-03-14
AU577057B2 (en) 1988-09-15
NO166944B (no) 1991-06-10
NO843592L (no) 1985-03-14
IE842324L (en) 1985-03-13
YU45968B (sh) 1992-12-21
DK433684D0 (da) 1984-09-11
PT79189B (en) 1986-08-14
YU157984A (en) 1988-04-30
JPS60100596A (ja) 1985-06-04
NO166944C (no) 1991-09-18
SU1435157A3 (ru) 1988-10-30
GR80335B (en) 1985-01-11
PT79189A (en) 1984-10-01

Similar Documents

Publication Publication Date Title
DK165749C (da) Grf-analoge peptider og farmaceutisk acceptable salte heraf samt farmaceutisk middel indeholdende disse
DK108388D0 (da) Piperazinylalkylheterocycliske forbindelser og farmaceutiske praeparater indeholdende disse
DK568487D0 (da) Norstatin- og norcyclostatinholdige polypeptider og farmaceutiske praeparater indeholdende disse.
DK555983D0 (da) Substituerede tetrapeptider og salte deraf samt farmaceutiske praeparater indeholdende disse forbindelser og fremgangsmader til fremstilling deraf
DK132489D0 (da) Rensetabletter til tandproteser
DK518984A (da) Zinkforbindelser og farmaceutiske praeparater indeholdende disse
DK214090A (da) 5-aminosulfonylalkyl-indolderivater, fremgangsmaade og mellemprodukt til fremstilling deraf samt farmaceutiske praeparater indeholdende disse
DK475684A (da) Phenothiazinderivater og farmaceutiske praeparater indeholdende phenothiazinderivaterne
DK162052C (da) D-2-aminoacyl-3-(z)-propenylcephalosporiner, fremgangsmaade til fremstilling deraf samt farmaceutiske praeparater indeholdende disse
DK161835C (da) Grf-analoge peptider og farmaceutisk acceptable salte deraf samt middel indeholdende disse
DK161096C (da) Hpgrf-analoge peptider, ikke toksiske salte heraf og midlet indeholdende disse
DK166214C (da) Gnrh-antagonistisk peptid og farmaceutisk acceptable salte heraf samt farmaceutisk praeparat indeholdende peptidet
DK163990C (da) Oxindol-3-carboxamid-derivater og farmaceutiske praeparater indeholdende disse
DK116989D0 (da) Polypeptider samt farmaceutiske praeparater indeholdende disse forbindelser
DK392284D0 (da) Lh-rh-antagonister og fremgangsmaade til fremstilling deraf samt farmaceutisk middel indeholdende disse
DK78888D0 (da) Arylpiperazinylalkylenphenyl-heterocycliske forbindelser og farmaceutiske praeparater indeholdende disse
DK188286D0 (da) Phenylalkyl-2,3-dihydrobenzofuraner og analoge heraf samt praeparater indeholdende disse forbindelser
DK674589A (da) Benzenderivater og fremgangsmaade til fresmtilling deraf samt farmaceutiske midler indeholdende derivaterne
DK165977C (da) 1-aminophenyl-3-azabicyclooe3.1.0aahexan-2,4-dioner og farmaceutisk anvendelige salte deraf samt farmaceutiske praeparater indeholdende disse forbindelser
DK21785D0 (da) Dihydropyridinforbindelser og farmaceutiske praeparater indeholdende disse
DK130890D0 (da) Peptider og farmaceutiske midler indeholdende disse
DK4487D0 (da) Heterocycliske forbindelser og farmaceutiske praeparater indeholdende disse
DK81185A (da) Carboxicam-enolester-forbindelser og farmaceutiske praeparater indeholdende disse
DK344384D0 (da) 2-heterocyclylalkylthio-6-(alfa-hydroxyethyl)-2-penem-3-carboxylsyre-forbindelser og farmaceutiske praeparater indeholdende disse
DK492289A (da) 3-aryloxymethyl-cephalosporinderivater og fremgangsmaade til fremstilling deraf samt farmaceutisk middel indeholdende derivaterne

Legal Events

Date Code Title Description
PUP Patent expired