DK164785A - 9-deoxo-4''-deoxy-4''-amino-9a-aza-9a-homoerythro-mycin-forbindelser og deres 4''-epimere og farmaceutiske praeparater indeholdende disse samt mellemprodukter ved deres fremstilling - Google Patents

9-deoxo-4''-deoxy-4''-amino-9a-aza-9a-homoerythro-mycin-forbindelser og deres 4''-epimere og farmaceutiske praeparater indeholdende disse samt mellemprodukter ved deres fremstilling Download PDF

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Publication number
DK164785A
DK164785A DK164785A DK164785A DK164785A DK 164785 A DK164785 A DK 164785A DK 164785 A DK164785 A DK 164785A DK 164785 A DK164785 A DK 164785A DK 164785 A DK164785 A DK 164785A
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DK
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Prior art keywords
products
homoerythro
deoxo
epimers
aza
Prior art date
Application number
DK164785A
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Danish (da)
English (en)
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DK164785D0 (da
Inventor
James Robert Hauske
Arthur Adam Negal
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/600,252 external-priority patent/US4512982A/en
Application filed by Pfizer filed Critical Pfizer
Publication of DK164785D0 publication Critical patent/DK164785D0/da
Publication of DK164785A publication Critical patent/DK164785A/da

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK164785A 1984-04-13 1985-04-12 9-deoxo-4''-deoxy-4''-amino-9a-aza-9a-homoerythro-mycin-forbindelser og deres 4''-epimere og farmaceutiske praeparater indeholdende disse samt mellemprodukter ved deres fremstilling DK164785A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/600,252 US4512982A (en) 1984-04-13 1984-04-13 9α-Aza-9α-homoerythromycin compounds, pharmaceutical composition and therapeutic method
US06/616,529 US4518590A (en) 1984-04-13 1984-06-04 9α-Aza-9α-homoerythromycin compounds, pharmaceutical compositions and therapeutic method

Publications (2)

Publication Number Publication Date
DK164785D0 DK164785D0 (da) 1985-04-12
DK164785A true DK164785A (da) 1985-12-10

Family

ID=27083554

Family Applications (1)

Application Number Title Priority Date Filing Date
DK164785A DK164785A (da) 1984-04-13 1985-04-12 9-deoxo-4''-deoxy-4''-amino-9a-aza-9a-homoerythro-mycin-forbindelser og deres 4''-epimere og farmaceutiske praeparater indeholdende disse samt mellemprodukter ved deres fremstilling

Country Status (19)

Country Link
US (1) US4518590A (OSRAM)
EP (1) EP0159856B1 (OSRAM)
KR (1) KR860002111B1 (OSRAM)
AU (1) AU549235B2 (OSRAM)
CA (1) CA1234805A (OSRAM)
DE (1) DE3565267D1 (OSRAM)
DK (1) DK164785A (OSRAM)
EG (1) EG17459A (OSRAM)
ES (3) ES8607335A1 (OSRAM)
FI (1) FI851449A7 (OSRAM)
GR (1) GR850900B (OSRAM)
HU (1) HU195668B (OSRAM)
IE (1) IE57739B1 (OSRAM)
IL (1) IL74865A (OSRAM)
NO (1) NO161497C (OSRAM)
NZ (1) NZ211769A (OSRAM)
PH (1) PH21185A (OSRAM)
PT (1) PT80270B (OSRAM)
YU (3) YU62385A (OSRAM)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5075289A (en) * 1988-06-07 1991-12-24 Abbott Laboratories 9-r-azacyclic erythromycin antibiotics
US4904644A (en) * 1988-08-03 1990-02-27 Schering Corporation Antimicrobial compound isolated from Actinomadura fulva subsp indica
DE69227713D1 (de) 1991-03-15 1999-01-14 Merck & Co Inc 9-Deoxo-9(Z)-hydroxyiminoerythromycin A und O-Derivate hiervon
US5912331A (en) * 1991-03-15 1999-06-15 Merck & Co., Inc. Process for the preparation of 9-deoxo-9(Z)-hydroxyiminoerythromycin A
US5985844A (en) * 1992-03-26 1999-11-16 Merck & Co., Inc. Homoerythromycin A derivatives modified at the 4"-and 8A-positions
US5538961A (en) * 1991-04-09 1996-07-23 Abbott Laboratories Macrocyclic lactam prokinetic agents
US5189159A (en) * 1992-04-02 1993-02-23 Merck & Co., Inc. 8a-AZA-8a-homoerythromycin cyclic iminoethers
US5523399A (en) * 1991-12-27 1996-06-04 Taisho Pharmaceutical Co., Ltd. 5-O-desosaminylerythronolide derivatives
US5215980A (en) * 1992-01-17 1993-06-01 Merck & Co., Inc. 10-AZA-9-deoxo-11-deoxy-erythromycin A and derivatives thereof
US5210235A (en) * 1992-08-26 1993-05-11 Merck & Co., Inc. Methods of elaborating erythromycin fragments into amine-containing fragments of azalide antibiotics
US5332807A (en) * 1993-04-14 1994-07-26 Merck & Co., Inc. Process of producing 8A- and 9A-azalide antibiotics
CA2162401C (en) * 1993-05-19 1998-11-03 Bingwei V. Yang Intermediate for azithromycin
US5441939A (en) * 1994-03-04 1995-08-15 Pfizer Inc. 3"-desmethoxy derivatives of erythromycin and azithromycin
FR2739620B1 (fr) * 1995-10-09 1997-12-19 Roussel Uclaf Nouveaux derives de la 5-0-desosaminyl 6-o-methyl erythronolide a, leur procede de preparation et leur application a la preparation de produits biologiquement actifs
USRE38426E1 (en) * 1995-10-09 2004-02-10 Aventis Pharma S.A. 5-O-deosaminyl 6-O-methyl erythronolide A derivatives, preparation method therefor and use thereof for preparing biologically active materials
ATE306491T1 (de) 2000-08-23 2005-10-15 Wockhardt Ltd Verfahren zur herstellung von wasserfreiem azithromycin
BR0209241A (pt) 2001-04-27 2004-06-15 Pfizer Prod Inc Processo para preparação de derivados de9-deoxo-9a-aza-9a-homoeritromicina a 4-substituida
WO2003070254A1 (en) 2002-02-15 2003-08-28 Sympore Gmbh Antibiotic conjugates
WO2003070174A2 (en) 2002-02-15 2003-08-28 Sympore Gmbh Conjugates of biologically active compounds, methods for their preparation and use, formulation and pharmaceutical applications thereof
WO2003070173A2 (en) 2002-02-15 2003-08-28 Sympore Gmbh Conjugates of biologically active compounds, methods for their preparation and use, formulation and pharmaceutical applications thereof
GB0310992D0 (en) * 2003-05-13 2003-06-18 Glaxo Group Ltd Novel compounds
US7468428B2 (en) * 2004-03-17 2008-12-23 App Pharmaceuticals, Llc Lyophilized azithromycin formulation
US20060116336A1 (en) * 2004-03-17 2006-06-01 American Pharmaceutical Partners, Inc. Lyophilized azithromycin formulation

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE445223B (sv) * 1977-02-04 1986-06-09 Pfizer Sett att framstella 4"-amino-erytomylin-a-derivat
US4150220A (en) * 1977-02-04 1979-04-17 Pfizer Inc. Semi-synthetic 4"-erythromycin A derivatives
US4180654A (en) * 1978-01-03 1979-12-25 Pfizer Inc. 4"-Deoxy-4"-acylamido derivatives of oleandomycin, erythromycin and erythromycin carbonate
YU43116B (en) * 1979-04-02 1989-04-30 Pliva Pharm & Chem Works Process for preparing 11-aza-4-o-cladinosyl-6-o-desosaminyl-15-ethyl-7,13,14-trihydroxy-3,5,7,9,12,14-hexamethyl-oxacyclopentadecane-2-one(11-aza-10-deox
YU43006B (en) * 1981-03-06 1989-02-28 Pliva Pharm & Chem Works Process for preparing n-methyl-11-aza-10-deoxo-10-dihydro erythromycin and derivatives thereof
US4474768A (en) * 1982-07-19 1984-10-02 Pfizer Inc. N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor
US4465674A (en) * 1983-09-06 1984-08-14 Pfizer Inc. Azahomoerythromycin D derivative and intermediates therefor

Also Published As

Publication number Publication date
PH21185A (en) 1987-08-12
KR860002111B1 (ko) 1986-11-26
US4518590A (en) 1985-05-21
IL74865A0 (en) 1985-07-31
NO851466L (no) 1985-10-14
ES8607335A1 (es) 1986-06-16
FI851449L (fi) 1985-10-14
KR850007435A (ko) 1985-12-04
IE57739B1 (en) 1993-03-24
YU62385A (en) 1988-02-29
PT80270B (pt) 1987-10-20
NO161497C (no) 1989-08-23
ES542134A0 (es) 1986-06-16
NZ211769A (en) 1987-10-30
ES8705458A1 (es) 1987-05-01
EP0159856A2 (en) 1985-10-30
GR850900B (OSRAM) 1985-11-25
ES8704965A1 (es) 1987-04-16
IL74865A (en) 1987-12-31
EG17459A (en) 1992-12-30
DK164785D0 (da) 1985-04-12
FI851449A0 (fi) 1985-04-11
FI851449A7 (fi) 1985-10-14
DE3565267D1 (en) 1988-11-03
NO161497B (no) 1989-05-16
EP0159856B1 (en) 1988-09-28
PT80270A (en) 1985-05-01
HUT37629A (en) 1986-01-23
IE850912L (en) 1985-10-13
CA1234805A (en) 1988-04-05
YU126787A (en) 1988-02-29
HU195668B (en) 1988-06-28
ES551503A0 (es) 1987-04-16
YU126887A (en) 1988-02-29
ES551502A0 (es) 1987-05-01
EP0159856A3 (en) 1986-03-19
AU4107085A (en) 1985-10-17
AU549235B2 (en) 1986-01-23

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