DK163997C - Analogifremgangsmaade til fremstilling af 17beta-amino-16alfa-hydroxysteroider af androstan- og oestranraekken - Google Patents

Analogifremgangsmaade til fremstilling af 17beta-amino-16alfa-hydroxysteroider af androstan- og oestranraekken

Info

Publication number
DK163997C
DK163997C DK039981A DK39981A DK163997C DK 163997 C DK163997 C DK 163997C DK 039981 A DK039981 A DK 039981A DK 39981 A DK39981 A DK 39981A DK 163997 C DK163997 C DK 163997C
Authority
DK
Denmark
Prior art keywords
amino
esterified
methyl
carbon atoms
free
Prior art date
Application number
DK039981A
Other languages
English (en)
Other versions
DK39981A (da
DK163997B (da
Inventor
Thomas Sleigh
David Samuel Savage
Filippus Johannes Zeelen
Original Assignee
Akzo Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nv filed Critical Akzo Nv
Publication of DK39981A publication Critical patent/DK39981A/da
Publication of DK163997B publication Critical patent/DK163997B/da
Application granted granted Critical
Publication of DK163997C publication Critical patent/DK163997C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0059—Estrane derivatives substituted in position 17 by a keto group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0062—Estrane derivatives substituted in position 17 alfa not substituted in position 17 beta
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • C07J41/0011—Unsubstituted amino radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • C07J41/0027—Azides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0036—Nitrogen-containing hetero ring
    • C07J71/0042—Nitrogen only
    • C07J71/0052—Nitrogen only at position 16(17)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0036—Nitrogen-containing hetero ring
    • C07J71/0057—Nitrogen and oxygen
    • C07J71/0068—Nitrogen and oxygen at position 16(17)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK039981A 1980-01-30 1981-01-29 Analogifremgangsmaade til fremstilling af 17beta-amino-16alfa-hydroxysteroider af androstan- og oestranraekken DK163997C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8003053 1980-01-30
GB8003053 1980-01-30

Publications (3)

Publication Number Publication Date
DK39981A DK39981A (da) 1981-07-31
DK163997B DK163997B (da) 1992-04-27
DK163997C true DK163997C (da) 1992-09-21

Family

ID=10510984

Family Applications (1)

Application Number Title Priority Date Filing Date
DK039981A DK163997C (da) 1980-01-30 1981-01-29 Analogifremgangsmaade til fremstilling af 17beta-amino-16alfa-hydroxysteroider af androstan- og oestranraekken

Country Status (13)

Country Link
EP (1) EP0033561B1 (da)
JP (1) JPS56120699A (da)
AT (1) ATE3298T1 (da)
AU (1) AU542419B2 (da)
CA (1) CA1167837A (da)
DE (1) DE3160232D1 (da)
DK (1) DK163997C (da)
ES (1) ES8300788A1 (da)
FI (1) FI69631C (da)
GR (1) GR73137B (da)
HU (1) HU185441B (da)
IE (1) IE51100B1 (da)
ZA (1) ZA81348B (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19917930A1 (de) * 1999-04-15 2000-10-19 Schering Ag Ent-Steroide als selektiv wirksame Estrogene
JP2004518637A (ja) 2000-11-03 2004-06-24 ワシントン・ユニバーシティ 細胞保護活性を有する修飾されたヒドロキシ置換芳香族構造体
JPWO2005026190A1 (ja) * 2003-09-10 2010-02-25 学校法人日本大学 アミノ化環状化合物の製造方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL104598C (da) * 1959-07-23
GB1439605A (en) * 1972-07-14 1976-06-16 Akzo Nv 2beta-hydroxy-3-alpha-amino-steroids and derivatives thereof and the processes for their preparation
GB2030569A (en) * 1978-10-03 1980-04-10 Akzo Nv Amino hydroxy steroids and derivatives thereof

Also Published As

Publication number Publication date
DK39981A (da) 1981-07-31
ES498942A0 (es) 1982-11-16
FI69631C (fi) 1986-03-10
ES8300788A1 (es) 1982-11-16
ATE3298T1 (de) 1983-05-15
ZA81348B (en) 1982-02-24
AU542419B2 (en) 1985-02-21
AU6664981A (en) 1981-08-06
HU185441B (en) 1985-02-28
EP0033561A1 (en) 1981-08-12
GR73137B (da) 1984-02-07
FI69631B (fi) 1985-11-29
JPH0115518B2 (da) 1989-03-17
DE3160232D1 (en) 1983-06-16
CA1167837A (en) 1984-05-22
FI810255L (fi) 1981-07-31
JPS56120699A (en) 1981-09-22
IE51100B1 (en) 1986-10-01
EP0033561B1 (en) 1983-05-11
IE810107L (en) 1981-07-30
DK163997B (da) 1992-04-27

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Legal Events

Date Code Title Description
PBP Patent lapsed