DK162771C - 17-oxazolinsteroider, samt fremgangsmaade til deres fremstilling - Google Patents

17-oxazolinsteroider, samt fremgangsmaade til deres fremstilling

Info

Publication number
DK162771C
DK162771C DK487081A DK487081A DK162771C DK 162771 C DK162771 C DK 162771C DK 487081 A DK487081 A DK 487081A DK 487081 A DK487081 A DK 487081A DK 162771 C DK162771 C DK 162771C
Authority
DK
Denmark
Prior art keywords
insteroids
oxazoline
procedure
preparation
oxazoline insteroids
Prior art date
Application number
DK487081A
Other languages
Danish (da)
English (en)
Other versions
DK162771B (da
DK487081A (da
Inventor
Derek Harold Richard Barton
William Branks Motherwell
Samir Zard Zard
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of DK487081A publication Critical patent/DK487081A/da
Publication of DK162771B publication Critical patent/DK162771B/da
Application granted granted Critical
Publication of DK162771C publication Critical patent/DK162771C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/006—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton spiro-condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of only two carbon atoms, e.g. pregnane derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
    • C07J7/0085—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Steroid Compounds (AREA)
DK487081A 1980-11-05 1981-11-04 17-oxazolinsteroider, samt fremgangsmaade til deres fremstilling DK162771C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8023575 1980-11-05
FR8023575A FR2493324B1 (fr) 1980-11-05 1980-11-05

Publications (3)

Publication Number Publication Date
DK487081A DK487081A (da) 1982-05-06
DK162771B DK162771B (da) 1991-12-09
DK162771C true DK162771C (da) 1992-04-27

Family

ID=9247684

Family Applications (1)

Application Number Title Priority Date Filing Date
DK487081A DK162771C (da) 1980-11-05 1981-11-04 17-oxazolinsteroider, samt fremgangsmaade til deres fremstilling

Country Status (14)

Country Link
US (1) US4401596A (fr)
JP (1) JPS57106700A (fr)
AT (1) AT386602B (fr)
CH (1) CH652726A5 (fr)
DE (1) DE3144009A1 (fr)
DK (1) DK162771C (fr)
FI (1) FI72526C (fr)
FR (1) FR2493324B1 (fr)
GB (1) GB2086907B (fr)
HU (1) HU183666B (fr)
IT (1) IT1171613B (fr)
NL (1) NL8104985A (fr)
PT (1) PT73933B (fr)
SE (1) SE440505B (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0123736A1 (fr) * 1983-04-29 1984-11-07 Gist-Brocades N.V. Procédé de préparation de 21-hydroxy-20-céto-delta-16-stéroides et intermédiaires obtenus
US4548748A (en) * 1984-02-03 1985-10-22 The Upjohn Company Cyanohydrin process
FR2559156B1 (fr) * 1984-02-03 1989-03-24 Roussel Uclaf Procede de preparation de derives de la prednisone et produits intermediaires de ce procede
FR2620708B1 (fr) * 1984-02-03 1994-11-04 Roussel Uclaf Nouveaux produits industriels, leur procede de preparation et leur application
US4585590A (en) * 1984-02-03 1986-04-29 The Upjohn Company Cyanohydrin process
EP0153001B1 (fr) * 1984-02-03 1992-03-11 The Upjohn Company Stéroides porteurs d'un groupe énamide ou énimide et leur préparation
US4831131A (en) * 1984-02-03 1989-05-16 The Upjohn Company 11β,17α-Dihydroxy-17β-cyano-androstanes
FR2571727B1 (fr) * 1984-10-16 1987-06-12 Roussel Uclaf Nouveaux produits steroides comportant, en position 23, un radical dihydro oxazolyle, leur procede de preparation, leur application a la preparation de produits de la serie des 20 cetopregnanes et intermediaires de cette application
AU618350B2 (en) * 1988-04-08 1991-12-19 Aventis Pharma S.A. 9-alpha-hydroxy-17-methylene steroids, process for their preparation and their use in the preparation of corticosteroids
IL96459A0 (en) * 1989-11-27 1991-08-16 Schering Corp Process for dehydrating corticosteroid intermediates

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3338892A (en) * 1964-11-24 1967-08-29 Lilly Co Eli Steroidal carbamic acid-gamma-lactones
US3646012A (en) * 1967-10-05 1972-02-29 Wyeth John & Brother Ltd Enamine salt protection of steroidal alpha beta-unsaturated ketones
CH549001A (de) * 1970-04-17 1974-05-15 Ciba Geigy Ag Verfahren zur herstellung neuer halogensteroide.
US4232013A (en) * 1977-12-03 1980-11-04 Lark S.P.A. 16,17-Pyrazolino- and 16,17-isopyrazolino-1,4-pregnadiene derivatives
HU178397B (en) * 1978-04-01 1982-04-28 Gyogyszerkutato Intezet Process for preparing substituted derivatives of steroid-spiro-oxazolidione derivatives

Also Published As

Publication number Publication date
FR2493324B1 (fr) 1983-01-21
DK162771B (da) 1991-12-09
FR2493324A1 (fr) 1982-05-07
NL8104985A (nl) 1982-06-01
FI72526B (fi) 1987-02-27
DK487081A (da) 1982-05-06
US4401596A (en) 1983-08-30
AT386602B (de) 1988-09-26
SE8105686L (sv) 1982-05-06
JPS57106700A (en) 1982-07-02
HU183666B (en) 1984-05-28
IT8149576A0 (it) 1981-10-27
PT73933B (fr) 1983-11-30
CH652726A5 (fr) 1985-11-29
FI813459L (fi) 1982-05-06
JPH026359B2 (fr) 1990-02-08
FI72526C (fi) 1987-06-08
SE440505B (sv) 1985-08-05
DE3144009A1 (de) 1982-06-16
GB2086907B (en) 1984-12-12
GB2086907A (en) 1982-05-19
IT1171613B (it) 1987-06-10
PT73933A (fr) 1981-12-01
ATA475081A (de) 1988-02-15

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PBP Patent lapsed