FI813459L - Nya 17-oxazolinsteroidderivat deras framstaellningsfoerfarande och tillaempning vid framstaellning av kortikosteroider - Google Patents

Nya 17-oxazolinsteroidderivat deras framstaellningsfoerfarande och tillaempning vid framstaellning av kortikosteroider

Info

Publication number
FI813459L
FI813459L FI813459A FI813459A FI813459L FI 813459 L FI813459 L FI 813459L FI 813459 A FI813459 A FI 813459A FI 813459 A FI813459 A FI 813459A FI 813459 L FI813459 L FI 813459L
Authority
FI
Finland
Prior art keywords
oxazolinsteroidderivat
kortikosteroider
tillaempning
nya
vid framstaellning
Prior art date
Application number
FI813459A
Other languages
English (en)
Other versions
FI72526B (fi
FI72526C (fi
Inventor
Derek Harold Richard Barton
William Branks Motherwell
Zard Samir Zard
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of FI813459L publication Critical patent/FI813459L/fi
Publication of FI72526B publication Critical patent/FI72526B/fi
Application granted granted Critical
Publication of FI72526C publication Critical patent/FI72526C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/006—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton spiro-condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of only two carbon atoms, e.g. pregnane derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
    • C07J7/0085—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Steroid Compounds (AREA)
FI813459A 1980-11-05 1981-11-03 Nya 17-oxazolinsteroidderivat, deras framstaellningsfoerfarande och tillaempning vid framstaellning av kortikosteroider. FI72526C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8023575A FR2493324B1 (fi) 1980-11-05 1980-11-05
FR8023575 1980-11-05

Publications (3)

Publication Number Publication Date
FI813459L true FI813459L (fi) 1982-05-06
FI72526B FI72526B (fi) 1987-02-27
FI72526C FI72526C (fi) 1987-06-08

Family

ID=9247684

Family Applications (1)

Application Number Title Priority Date Filing Date
FI813459A FI72526C (fi) 1980-11-05 1981-11-03 Nya 17-oxazolinsteroidderivat, deras framstaellningsfoerfarande och tillaempning vid framstaellning av kortikosteroider.

Country Status (14)

Country Link
US (1) US4401596A (fi)
JP (1) JPS57106700A (fi)
AT (1) AT386602B (fi)
CH (1) CH652726A5 (fi)
DE (1) DE3144009A1 (fi)
DK (1) DK162771C (fi)
FI (1) FI72526C (fi)
FR (1) FR2493324B1 (fi)
GB (1) GB2086907B (fi)
HU (1) HU183666B (fi)
IT (1) IT1171613B (fi)
NL (1) NL8104985A (fi)
PT (1) PT73933B (fi)
SE (1) SE440505B (fi)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0123736A1 (en) * 1983-04-29 1984-11-07 Gist-Brocades N.V. New process for the preparation of 21-hydroxy-20-keto-delta 16-steroids and new intermediate compounds formed in this process
US4548748A (en) * 1984-02-03 1985-10-22 The Upjohn Company Cyanohydrin process
DE3585547D1 (de) * 1984-02-03 1992-04-16 Upjohn Co Steroide mit einer enamid- oder enimidgruppe sowie ihre herstellung.
US4831131A (en) * 1984-02-03 1989-05-16 The Upjohn Company 11β,17α-Dihydroxy-17β-cyano-androstanes
FR2559156B1 (fr) * 1984-02-03 1989-03-24 Roussel Uclaf Procede de preparation de derives de la prednisone et produits intermediaires de ce procede
FR2620708B1 (fr) * 1984-02-03 1994-11-04 Roussel Uclaf Nouveaux produits industriels, leur procede de preparation et leur application
US4585590A (en) * 1984-02-03 1986-04-29 The Upjohn Company Cyanohydrin process
FR2571727B1 (fr) * 1984-10-16 1987-06-12 Roussel Uclaf Nouveaux produits steroides comportant, en position 23, un radical dihydro oxazolyle, leur procede de preparation, leur application a la preparation de produits de la serie des 20 cetopregnanes et intermediaires de cette application
HU208437B (en) * 1988-04-08 1993-10-28 Roussel Uclaf Process for producing 9-alpha-hydroxy- -17-methylene-steroides for synthetizing corticosteroides
NZ236206A (en) * 1989-11-27 1993-03-26 Schering Corp Preparation of 2'-methyl-4'-methylenespiro(androstadiene-17,5'(4'h)-oxazol)-3-one derivatives from pregn-5-en-20-ylideneacetamide derivatives by treatment with vilsmeier reagent or acid

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3338892A (en) * 1964-11-24 1967-08-29 Lilly Co Eli Steroidal carbamic acid-gamma-lactones
US3646012A (en) * 1967-10-05 1972-02-29 Wyeth John & Brother Ltd Enamine salt protection of steroidal alpha beta-unsaturated ketones
CH549001A (de) * 1970-04-17 1974-05-15 Ciba Geigy Ag Verfahren zur herstellung neuer halogensteroide.
US4232013A (en) * 1977-12-03 1980-11-04 Lark S.P.A. 16,17-Pyrazolino- and 16,17-isopyrazolino-1,4-pregnadiene derivatives
HU178397B (en) * 1978-04-01 1982-04-28 Gyogyszerkutato Intezet Process for preparing substituted derivatives of steroid-spiro-oxazolidione derivatives

Also Published As

Publication number Publication date
IT8149576A0 (it) 1981-10-27
NL8104985A (nl) 1982-06-01
CH652726A5 (fr) 1985-11-29
JPS57106700A (en) 1982-07-02
US4401596A (en) 1983-08-30
DK487081A (da) 1982-05-06
IT1171613B (it) 1987-06-10
DK162771C (da) 1992-04-27
FR2493324B1 (fi) 1983-01-21
HU183666B (en) 1984-05-28
GB2086907B (en) 1984-12-12
DE3144009A1 (de) 1982-06-16
SE440505B (sv) 1985-08-05
GB2086907A (en) 1982-05-19
PT73933B (fr) 1983-11-30
DK162771B (da) 1991-12-09
PT73933A (fr) 1981-12-01
FI72526B (fi) 1987-02-27
FR2493324A1 (fi) 1982-05-07
ATA475081A (de) 1988-02-15
AT386602B (de) 1988-09-26
SE8105686L (sv) 1982-05-06
FI72526C (fi) 1987-06-08
JPH026359B2 (fi) 1990-02-08

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Legal Events

Date Code Title Description
MM Patent lapsed
MM Patent lapsed

Owner name: ROUSSEL UCLAF SOCIETE ANONYME