FI813971L - Nya pyrimidoner deras framstaellning och deras anvaendning saosom laekemedel - Google Patents
Nya pyrimidoner deras framstaellning och deras anvaendning saosom laekemedelInfo
- Publication number
- FI813971L FI813971L FI813971A FI813971A FI813971L FI 813971 L FI813971 L FI 813971L FI 813971 A FI813971 A FI 813971A FI 813971 A FI813971 A FI 813971A FI 813971 L FI813971 L FI 813971L
- Authority
- FI
- Finland
- Prior art keywords
- deras
- pyrimidoner
- nya
- framstaellning och
- laekemedel
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/88—Oxygen atoms
- C07D239/91—Oxygen atoms with aryl or aralkyl radicals attached in position 2 or 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
- C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
- C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D265/20—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in position 4
- C07D265/22—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19803046871 DE3046871A1 (de) | 1980-12-12 | 1980-12-12 | Neue chinazolinone, ihre herstellung und ihre verwendung als arzneimittel |
DE19813115447 DE3115447A1 (de) | 1981-04-16 | 1981-04-16 | Neue pyrimidinone, ihre herstellung und ihre verwendung als arzneimittel |
Publications (1)
Publication Number | Publication Date |
---|---|
FI813971L true FI813971L (fi) | 1982-06-13 |
Family
ID=25789685
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI813971A FI813971L (fi) | 1980-12-12 | 1981-12-10 | Nya pyrimidoner deras framstaellning och deras anvaendning saosom laekemedel |
Country Status (22)
Country | Link |
---|---|
US (1) | US4379788A (fi) |
EP (1) | EP0054132B1 (fi) |
AR (1) | AR227567A1 (fi) |
AU (1) | AU543568B2 (fi) |
CA (1) | CA1217767A (fi) |
CS (1) | CS227024B2 (fi) |
DD (1) | DD208151A5 (fi) |
DE (1) | DE3166627D1 (fi) |
DK (1) | DK525481A (fi) |
ES (2) | ES8207156A1 (fi) |
FI (1) | FI813971L (fi) |
GB (1) | GB2090249B (fi) |
GR (1) | GR76952B (fi) |
HU (1) | HU187384B (fi) |
IL (1) | IL64504A (fi) |
MY (1) | MY8700562A (fi) |
NO (1) | NO814239L (fi) |
NZ (1) | NZ199254A (fi) |
PH (1) | PH18930A (fi) |
PL (1) | PL135330B1 (fi) |
PT (1) | PT74116B (fi) |
SU (1) | SU1056900A3 (fi) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4460589A (en) * | 1980-10-03 | 1984-07-17 | The Upjohn Company | Process for treating hypertension |
US4379778A (en) * | 1980-10-10 | 1983-04-12 | Air Products And Chemicals, Inc. | Hydrogen peroxide synthesis |
DE3428476A1 (de) * | 1984-08-02 | 1986-02-13 | Basf Ag, 6700 Ludwigshafen | 4h-pyrido(2,3-d)(1,3)oxazin-4-on-derivate, verfahren zu ihrer herstellung und ihre verwendung zur bekaempfung unerwuenschten pflanzenwuchses |
DE3631294A1 (de) * | 1986-09-13 | 1988-03-24 | Thomae Gmbh Dr K | Neue synergistische kombination bestehend aus einem phosphodiesterase-hemmer und einem thromboxan-a(pfeil abwaerts)2(pfeil abwaerts)-antagonisten und deren verwendung bzw. herstellung |
US5037980A (en) * | 1988-04-18 | 1991-08-06 | American Cyanamid Company | Phenyl imidazo[1,2-a]pyrimidines |
GB8928346D0 (en) * | 1989-12-15 | 1990-02-21 | Smith Kline French Lab | Chemical compounds |
GB9126260D0 (en) * | 1991-12-11 | 1992-02-12 | Pfizer Ltd | Therapeutic agents |
GB9404485D0 (en) | 1994-03-09 | 1994-04-20 | Cancer Res Campaign Tech | Benzamide analogues |
HU228196B1 (en) * | 1997-11-12 | 2013-01-28 | Bayer Pharma AG | 2-phenyl substituted imidazotriazinones, process for their preparation and pharmaceutical compositions thereof |
AU2645299A (en) * | 1998-11-18 | 2000-06-05 | Elena Alexandrovna Izaxon | 6-(3-carboxymethylphenyl)-aminouracyl having a biological activity |
US20040102324A1 (en) | 2002-02-28 | 2004-05-27 | Annis Gary David | Heterocyclic diamide invertebrate pest control agents |
US6642244B2 (en) | 2001-03-16 | 2003-11-04 | Bristol-Myers Squibb Co. | Pyrazolopyridopyrimidine inhibitors of cGMP phosphodiesterase |
JP2004532848A (ja) * | 2001-04-23 | 2004-10-28 | ユニバーシティ オブ バージニア パテント ファウンデーション | 好血管形成剤としての新規なフタルイミドミミックスの合成および評価 |
BR0209541A (pt) * | 2001-05-09 | 2004-04-20 | Bayer Healthcare Ag | Uso das imidazotriazinonas 2-fenil-substituìdas |
DE10232113A1 (de) | 2002-07-16 | 2004-01-29 | Bayer Ag | Vardenafil Hydrochlorid Trihydrat enthaltende Arzneimittel |
JP2007517071A (ja) * | 2003-12-19 | 2007-06-28 | メルク エンド カムパニー インコーポレーテッド | 有糸分裂キネシン阻害剤 |
SE0401342D0 (sv) * | 2004-05-25 | 2004-05-25 | Astrazeneca Ab | Therapeutic compounds |
SE0401345D0 (sv) * | 2004-05-25 | 2004-05-25 | Astrazeneca Ab | Therapeutic compounds: Pyridine as scaffold |
CA2569081A1 (en) | 2004-05-31 | 2005-12-08 | Takashi Mizutani | Quinazoline derivative |
DE102005001989A1 (de) * | 2005-01-15 | 2006-07-20 | Bayer Healthcare Ag | Intravenöse Formulierungen von PDE-Inhibitoren |
DE102005009241A1 (de) * | 2005-03-01 | 2006-09-07 | Bayer Healthcare Ag | Arzneiformen mit kontrollierter Bioverfügbarkeit |
DE102005009240A1 (de) * | 2005-03-01 | 2006-09-07 | Bayer Healthcare Ag | Arzneiformen mit verbesserten pharmakokinetischen Eigenschaften |
CA2623657A1 (en) * | 2005-09-29 | 2007-04-12 | Bayer Healthcare Ag | Pde inhibitors and combinations thereof for the treatment of urological disorders |
CA2663436A1 (en) * | 2006-10-04 | 2008-04-10 | Pfizer Products Inc. | Pyrido[4,3-d]pyrimidin-4(3h)-one derivatives as calcium receptor antagonists |
EP2167057A1 (en) * | 2007-06-13 | 2010-03-31 | Bayer HealthCare AG | Pde inhibitors for the treatment of hearing impairment |
CN101531638B (zh) * | 2008-03-13 | 2011-12-28 | 中国科学院广州生物医药与健康研究院 | 用作雌激素相关受体调节剂的化合物及其应用 |
US20110124634A1 (en) * | 2008-05-13 | 2011-05-26 | Poniard Pharmaceuticals, Inc. | Bioactive compounds for treatment of cancer and neurodegenerative diseases |
CN101628913B (zh) | 2008-07-18 | 2013-01-23 | 中国科学院广州生物医药与健康研究院 | 用作雌激素相关受体调节剂的化合物及其应用 |
BR112015006524A8 (pt) * | 2012-09-26 | 2019-08-20 | Merck Patent Gmbh | derivados de quinazolinona como inibidores de parp, seu processo de preparação, seu uso, medicamentos e conjunto (kit) |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3265697A (en) * | 1964-09-04 | 1966-08-09 | Shulton Inc | 2-p-dialkylaminoalkoxyphenyl-2, 3-dihydro-4 (1h)-quinazolinones and their derivatives |
DE1939109A1 (de) * | 1968-08-31 | 1970-03-05 | Troponwerke Dinklage & Co | 2-Methyl-3-[2-(2-diaethylaminoaethoxy)-phenyl]-chinazolinon-(4) und Verfahren zu seiner Herstellung |
US3862191A (en) * | 1972-09-27 | 1975-01-21 | Pfizer | Pyrido{8 2,3-d{9 pyrimidin-4(3H)-one |
-
1981
- 1981-10-21 DE DE8181108623T patent/DE3166627D1/de not_active Expired
- 1981-10-21 EP EP81108623A patent/EP0054132B1/de not_active Expired
- 1981-11-18 SU SU813354550A patent/SU1056900A3/ru active
- 1981-11-26 DK DK525481A patent/DK525481A/da not_active Application Discontinuation
- 1981-12-04 US US06/327,348 patent/US4379788A/en not_active Expired - Fee Related
- 1981-12-07 ES ES507761A patent/ES8207156A1/es not_active Expired
- 1981-12-07 DD DD81235494A patent/DD208151A5/de unknown
- 1981-12-10 IL IL64504A patent/IL64504A/xx unknown
- 1981-12-10 CS CS819180A patent/CS227024B2/cs unknown
- 1981-12-10 PL PL1981234175A patent/PL135330B1/pl unknown
- 1981-12-10 GR GR66768A patent/GR76952B/el unknown
- 1981-12-10 FI FI813971A patent/FI813971L/fi not_active Application Discontinuation
- 1981-12-11 CA CA000392067A patent/CA1217767A/en not_active Expired
- 1981-12-11 HU HU813747A patent/HU187384B/hu unknown
- 1981-12-11 AR AR287776A patent/AR227567A1/es active
- 1981-12-11 PT PT74116A patent/PT74116B/pt unknown
- 1981-12-11 GB GB8137458A patent/GB2090249B/en not_active Expired
- 1981-12-11 NZ NZ199254A patent/NZ199254A/en unknown
- 1981-12-11 PH PH26759A patent/PH18930A/en unknown
- 1981-12-11 NO NO814239A patent/NO814239L/no unknown
- 1981-12-11 AU AU78473/81A patent/AU543568B2/en not_active Ceased
-
1982
- 1982-04-30 ES ES82511835A patent/ES511835A0/es active Granted
-
1987
- 1987-12-30 MY MY562/87A patent/MY8700562A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
HU187384B (en) | 1985-12-28 |
ES8304096A1 (es) | 1983-02-16 |
GB2090249B (en) | 1984-08-22 |
AU543568B2 (en) | 1985-04-26 |
US4379788A (en) | 1983-04-12 |
PT74116A (de) | 1982-01-01 |
PL135330B1 (en) | 1985-10-31 |
CA1217767A (en) | 1987-02-10 |
EP0054132A1 (de) | 1982-06-23 |
MY8700562A (en) | 1987-12-31 |
ES507761A0 (es) | 1982-09-01 |
ES8207156A1 (es) | 1982-09-01 |
EP0054132B1 (de) | 1984-10-10 |
DD208151A5 (de) | 1984-03-28 |
SU1056900A3 (ru) | 1983-11-23 |
AU7847381A (en) | 1982-06-17 |
CS227024B2 (en) | 1984-04-16 |
IL64504A (en) | 1985-02-28 |
PT74116B (de) | 1983-12-19 |
PL234175A1 (fi) | 1982-08-16 |
IL64504A0 (en) | 1982-03-31 |
DK525481A (da) | 1982-06-13 |
NZ199254A (en) | 1985-02-28 |
GB2090249A (en) | 1982-07-07 |
GR76952B (fi) | 1984-09-04 |
NO814239L (no) | 1982-06-14 |
DE3166627D1 (en) | 1984-11-15 |
ES511835A0 (es) | 1983-02-16 |
PH18930A (en) | 1985-11-11 |
AR227567A1 (es) | 1982-11-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD | Application lapsed |
Owner name: DR. KARL THOMAE GESELLSCHAFT MIT |