DK162208B - DOSAGE DECOR - Google Patents
DOSAGE DECOR Download PDFInfo
- Publication number
- DK162208B DK162208B DK135585A DK135585A DK162208B DK 162208 B DK162208 B DK 162208B DK 135585 A DK135585 A DK 135585A DK 135585 A DK135585 A DK 135585A DK 162208 B DK162208 B DK 162208B
- Authority
- DK
- Denmark
- Prior art keywords
- unit
- dosing
- magazine
- metering
- recesses
- Prior art date
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01F—MEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
- G01F11/00—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it
- G01F11/10—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers moved during operation
- G01F11/12—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers moved during operation of the valve type, i.e. the separating being effected by fluid-tight or powder-tight movements
- G01F11/20—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers moved during operation of the valve type, i.e. the separating being effected by fluid-tight or powder-tight movements wherein the measuring chamber rotates or oscillates
- G01F11/24—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers moved during operation of the valve type, i.e. the separating being effected by fluid-tight or powder-tight movements wherein the measuring chamber rotates or oscillates for fluent solid material
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01F—MEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
- G01F11/00—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it
- G01F11/10—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers moved during operation
- G01F11/26—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers moved during operation wherein the measuring chamber is filled and emptied by tilting or inverting the supply vessel, e.g. bottle-emptying apparatus
- G01F11/261—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers moved during operation wherein the measuring chamber is filled and emptied by tilting or inverting the supply vessel, e.g. bottle-emptying apparatus for fluent solid material
Landscapes
- Physics & Mathematics (AREA)
- Fluid Mechanics (AREA)
- General Physics & Mathematics (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Medicinal Preparation (AREA)
- Basic Packing Technique (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Dental Tools And Instruments Or Auxiliary Dental Instruments (AREA)
- Filling Or Emptying Of Bunkers, Hoppers, And Tanks (AREA)
- Processing And Handling Of Plastics And Other Materials For Molding In General (AREA)
Description
iin
DK 162208 BDK 162208 B
Den foreliggende opfindelse angår en doseringsindretning beregnet til med stor nøjagtighed at dosere findelte eller granulerede stoffer eller mi krokapsl er (i det følgende betegnet under ét som pulverformet materiale) og indeholdende de farmakologisk aktive 5 stoffer.The present invention relates to a dosage device intended to dispense with high accuracy, finely divided or granulated substances or microcapsules (hereinafter referred to collectively as powdered material) and containing the pharmacologically active substances.
Adskillige lægemiddelpræparater administreres nu til dags i findelt eller granuleret form i form af mi krokapsl er. Disse stoffer fyldes i kapsler af hård gelatine, som er beregnet til oral administration, 10 og som synkes hele af patienten. Børn og voksne, som har vanskeligheder med at sluge en hel kapsel, anbefales at åbne kapslen og sprede indholdet henover et passende fødevarestykke og derefter synke det. Det er imidlertid vanskeligt at åbne kapslen og hælde indholdet ud uden at tabe noget af stoffet. Kapsler af hård gelatine 15 er en kostbar, men effektiv måde at administrere farmakologisk aktive stoffer på til patienter, som er i stand til at sluge kapslerne hele. Det er imidlertid ikke økonomisk fordelagtigt at anvende kapsler at hård gelatine, når patienten senere med visse vanskeligheder åbner kapslerne og hælder indholdet ud.Several drug preparations are nowadays administered in finely divided or granulated form in the form of microcapsules. These substances are filled into hard gelatin capsules, which are intended for oral administration, and are swallowed whole by the patient. Children and adults who have difficulty swallowing an entire capsule are advised to open the capsule and spread the contents across a suitable food piece and then swallow it. However, it is difficult to open the capsule and pour out the contents without dropping any of the substance. Hard gelatin 15 capsules are a costly but effective way to administer pharmacologically active substances to patients who are able to swallow the capsules whole. However, it is not economically advantageous to use hard gelatin capsules when the patient later, with certain difficulties, opens the capsules and pours the contents.
2020
Der har tidligere været foreslået doseringsindretninger, som muliggør en nøjagtig dosering af pulverformet materiale. F.eks. beskriver tysk offentliggørelsesskrift nr. 2 052 051 en doseringsindretning omfattende en betjeningsenhed og et magasin. Betjeningsenheden er 25 fastgjort relativt løst til huset på indretningen. Stoffer med små partikler vil derfor let falde på de glidende overflader mellem de to indbyrdes bevægelige enheder, således at soffet, som afgives, blokerer bevægelsen. Med en sådan doseringsindretning, som ikke har en tilførsel under tryk, er det vanskeligt at dosere små mængder af 30 findelte eller granulerede stoffer med den nøjagtighed, som er nødvendig ved dosering af lægemidler.Dosing devices have been proposed in the past which allow accurate dosing of powdered material. Eg. German Patent Specification No. 2,052,051 discloses a metering device comprising an operating unit and magazine. The control unit is attached relatively loosely to the housing of the device. Substances with small particles will therefore easily fall on the sliding surfaces between the two mutually moving units, so that the couch that is released blocks movement. With such a dosing device which does not have a pressurized feed, it is difficult to dispense small amounts of 30 finely divided or granulated substances with the accuracy required for dosing of drugs.
I henhold til den foreliggende opfindelse tilvejebringes der en doseringsindretning til dosering med stor nøjagtighed af et pulver-35 formet materiale indeholdende et farmakologisk aktivt stof, hvilken indretning omfatter et magasin, en roterbar doseringsenhed placeret op til magasinet, en udløbskanal og en betjeningsenhed, hvormed doseringsenheden og magasinet kan roteres i forhold til hinanden, og hvor doseringsenheden har en række opad åbne recesser, af hvilkeAccording to the present invention, there is provided a metering device for high accuracy metering of a powdered material containing a pharmacologically active substance comprising a magazine, a rotatable metering unit located up to the magazine, an outlet channel and an operating unit with which the metering unit and the magazine can be rotated relative to each other and wherein the metering unit has a series of upwardly open recesses, of which
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2 i det mindste én er åben mod magasinet til modtagelse af pulverfor-migt materiale derfra. Doseringsenheden ifølge opfindelsen er ejendommelig ved, at der er tilvejebragt skrabere, som er således placeret, at de pakker og afstryger det pulverformede materiale i 5 recesserne og bringer dette ind i niveau med doseringsenhedens øvre overflade, idet betjeningsenheden på trinvis måde er i stand til at stille doseringsenheden i bestemte vinkelstillinger, og idet udløbskanalen er generelt opad forløbende og indrettet til i en af disse bestemte vinkel still inger at være forbundet med én af recesserne, 10 således at recessen kan tømmes ved at vende indretningen med bunden i vejret.2, at least one is open to the tray for receiving powdered material therefrom. The dosing unit according to the invention is characterized in that scrapers are provided which are packed so as to pack and coat the powdered material in the recesses and bring it into level with the upper surface of the dosing unit, the control unit being able to stepwise positioning the metering unit at certain angular positions, and the outlet channel generally extending upwardly and being arranged to be connected to one of the recesses in one of these particular angular positions, so that the recess can be emptied by flipping the device to the bottom.
Ved udformningen ifølge den foreliggende opfindelse forhindres stoffet i at komme i kontakt med de glidende overflader på de to i 15 forhold til hinanden bevægelige dele i doseringsindretningen og på denne måde kan tilførslen af hver dosis ske uden problemer. I doseringsindretningen ifølge opfindelsen gør skraberne det muligt at fylde recesserne i doseringsenhederne på en nøjagtig reproducerbar måde. En høj doseringsnøjagtighed kan således opnås ved rotationen 20 af doseringsenheden.In the embodiment of the present invention, the substance is prevented from contacting the sliding surfaces of the two movable portions of the dosing device in this way and in this way the delivery of each dose can be effected without difficulty. In the metering device according to the invention, the scrapers make it possible to fill the recesses in the metering units in an accurately reproducible manner. Thus, a high dosing accuracy can be obtained by the rotation 20 of the dosing unit.
For at lette forståelsen af opfindelsen skal den beskrives som et udførelseseksempel med henvisning til tegningen, på hvilken fig. 1 er et aksialt tværsnit gennem en udførelsesform for 25 doseringsindretningen ifølge opfindelsen, og fig. 2 er et tværsnit langs linien II-II ifølge fig. 1.In order to facilitate the understanding of the invention, it should be described as an exemplary embodiment with reference to the drawing, in which 1 is an axial cross-section through an embodiment of the dosing device according to the invention; and FIG. 2 is a cross-section along line II-II of FIG. First
Doseringsindretningen ifølge opfindelsen er fortrinsvis fremstillet af plastik og kan betragtes som indeholdende fire adskilte enheder 30 som følger:The dosing device according to the invention is preferably made of plastic and can be considered as containing four separate units 30 as follows:
En betjeningsenhed 1 ved bunden af doseringsindretningen, en fjederbelastet doseringsenhed 2, en skraberenhed 3, og et magasin 4 forsynet med en udløbskanal 5 for den afgivne dosis.An operating unit 1 at the bottom of the dosing device, a spring loaded dosing unit 2, a scraper unit 3, and a magazine 4 provided with an outlet channel 5 for the delivered dose.
3535
En yderligere separat del er vist på tegningen, og det foretrækkes, omend det ikke er nødvendigt, at denne har form som en plastikeller metalhætte 6, som fastholdes ved hjælp af en omløbende ribbe (ikke vist) ved den øverste del af betjeningsenheden. Denne ribbe holder hætten fast så den kan aftages efter ønske. En alternativA further separate portion is shown in the drawing, and it is preferred, although it is not necessary that it be shaped like a plastic or metal cap 6, which is held by a circumferential rib (not shown) at the upper portion of the operating unit. This rib holds the cap firmly so that it can be removed as desired. An alternative
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3 måde til forsegling af indretningen er at isætte en prop i toppen af udløbskanalen 5.3 way to seal the device is to insert a plug at the top of the outlet duct 5.
Ved den nedre midterste del af magasinet 4 er skraberenheden 3 5 fastgjort til den indvendige væg af magasinet, således at den ikke kan rotere i forhold til dette. Skraberenheden omfatter i realiteten den nederste del af udløbs kanal en 5, som er udformet ud i ét med magasinet 4. Af fig. 2 ses det mere tydeligt, at skraberenheden 3 omfatter fem radialt forløbende arme, som hver bærer en eftergivelig 10 skraber 8 i gi idekontakt med den øvre overflade af doseringsenheden 2, som for sin del er forsynet med seks langs en cirkel med mellemrum placerede let koniske recesser 7, der er placeret umiddelbart under skraberne 8. Fro at tjene som styr for rotationen af doseringsenheden 2 har skraberenheden et ydre omkredsskørt, der er i 15 indgreb med den cylindriske yderflade af doseringsenheden 2 og en kort indre ring, som er i indgreb med den øvre overflade af doseringsenheden inden for recesserne 7 for at forhindre blokering ved tilførslen. Doseringsenheden 2 belastes ved hjælp af en fjeder 9 med henblik på at presse doseringsenheden mod skraberenheden. Mellem 20 doseringsenheden, som har en fortandet ring 13 og fjederen, er der placeret en skive 14, som er fastlåst til magasinet. Betjeningsenheden 1, mod hvilken den anden ende af fjederen 9 hviler, har en fjedrende arm 12, som er i indgreb med den fortandede ring 13.At the lower middle portion of the magazine 4, the scraper assembly 35 is attached to the inside wall of the magazine so that it cannot rotate relative thereto. In effect, the scraper assembly comprises the lower portion of the outlet channel a 5 formed integrally with the magazine 4. From FIG. 2, it is more clearly seen that the scraper unit 3 comprises five radially extending arms, each carrying a resilient scraper 8 in contact with the upper surface of the metering unit 2, which, for its part, is provided with six along a slightly spaced circle recesses 7 located immediately below the scrapers 8. To serve as a guide for the rotation of the metering unit 2, the scraping unit has an outer circumferential skirt which engages the cylindrical outer surface of the metering unit 2 and a short inner ring which engages with the the upper surface of the metering unit within the recesses 7 to prevent blocking on delivery. The metering unit 2 is loaded by a spring 9 in order to push the metering unit against the scraper unit. Between the dosing unit having a toothed ring 13 and the spring, a disc 14 is placed which is locked to the magazine. The operating unit 1 against which the other end of the spring 9 rests has a resilient arm 12 which engages the toothed ring 13.
Skiven 14 regulerer i realiteten vinkelbevægelsen af betjeningsen-25 heden 1 og doseringsenheden 2, således at en af recesserne 7 altid vil standse i korrekt stilling, hvilket er umiddelbart under udløbskanalen 5 som vist på fig. 1. Endvidere reducerer skiven 14 friktionen mellem fjederen og doseringsenheden. I betjeningsenheden 1 er der et rum 10 som vist, hvilket rum er lukket ved hjælp af en porøs 30 pude og i rummet 10 kan der indsættes et tørremiddel, såsom silica gel, med henblik på at beskytte indholdet af indretningen mod luftens fugtighed. Indtrængen af fugtighed vil også blive reduceret ved hjælp af hætten 6.The disc 14 actually controls the angular movement of the control unit 1 and the metering unit 2, so that one of the recesses 7 will always stop in the correct position, which is immediately below the outlet channel 5 as shown in FIG. 1. Furthermore, the disc 14 reduces the friction between the spring and the metering unit. In the operating unit 1, there is a compartment 10 as shown, which compartment is closed by a porous pad and in the compartment 10 a desiccant such as silica gel can be inserted to protect the contents of the device from the humidity of the air. Humidity penetration will also be reduced by the cap 6.
35 Det pulverformede, farmakologisk aktive stof opbevares i magasinet 4, og den aktuelle doseringsoperation udføres med doseringsindretningen i den på fig. 1 viste oprette stilling, ved at rotere betjeningsenheden først i urets retning og derefter modsat. Palmekanismen, som dannes ved hjælp af den fortandede ring 13 og den fjedrendeThe powdered pharmacologically active substance is stored in magazine 4 and the actual dosing operation is performed with the dosing device of the embodiment shown in FIG. 1 by rotating the control unit first clockwise and then opposite. The palm mechanism, which is formed by the toothed ring 13 and the resilient
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4 arm 12, vil derved dreje doseringsenheden således at den første og derefter en anden reces kommer til syne umiddelbart under udløbskanalen. Alle recesserne passerer successivt magasinet og kan blive fyldt med det pulverformede materiale deri. Derved kan en forudbe-5 stemt mængde af pulverformet, farmakologisk aktivt stof blive doseret ved korrekt valg af størrelsen af recessen 7. Virkningen af skraberne 8 på skraberenheden 3 er først at trykke og sammenpresse det pulverformede materiale ned i recesserne og derefter nøjagtigt at afstryge det pulverformede materiale ved toppen af recesserne.4 arm 12 will thereby rotate the metering unit so that the first and then a second recess appears immediately below the outlet duct. All the recesses pass successively the magazine and can be filled with the powdered material therein. Thereby, a predetermined amount of powdered pharmacologically active substance can be dosed by properly selecting the size of the recess 7. The effect of the scrapers 8 on the scraper unit 3 is to first press and compress the powdered material into the recesses and then accurately coat it. powdered material at the top of the recesses.
10 Dette betyder, at når en reces 7 befinder sig umiddelbart under udløbskanalen 5, vil den være fuldstændigt og nøjagtigt fyldt.This means that when a recess 7 is immediately below the outlet duct 5, it will be completely and accurately filled.
Alt hvad der nu er nødvendigt er at vende doseringsindretningen med bunden i vejret, hvorefter det pulverformede materiale vil flyde ned 15 gennem udløbskanalen 5. Ved at vælge størrelsen af den reces, for hvilken stoffet skal doseres, kan man vælge størrelsen af en dosis, som fx kan varieres inden for vide grænser, fx fra 1 til 5 mg eller fra 5 til 200 mg. Antallet af recesser i doseringsenheden kan variere afhængigt af forskellige faktorer, såsom mængden af aktivt 20 stof, som skal administreres i hver dosis, de fysiske egenskaber af de aktive stoffer osv. I en foretrukken udførelsesform har doseringsenheden seks recesser og disse recesser er fortrinsvis cylindriske eller fortrinsvis keglestubformede som vist og indeholder fortrinsvis en dosis aktivt stof.All that is needed now is to flip the dosing device to the bottom, after which the powdered material will flow down 15 through the outlet duct 5. By selecting the size of the recess for which the drug is to be dosed, one can select the size of a dose which for example, can be varied within wide limits, for example from 1 to 5 mg or from 5 to 200 mg. The number of recesses in the dosage unit may vary depending on various factors such as the amount of active substance to be administered in each dose, the physical properties of the active substances, etc. In a preferred embodiment, the dosage unit has six recesses and these recesses are preferably cylindrical or preferably cone-shaped as shown and preferably contains a dose of active substance.
2525
Størrelsen arf magasinet kan vælges således at den passer til de forventede fordringer til et bestemt aktivt stof. I doseringsindretningen kan magasinet fx indeholde tilstrækkeligt aktivt stof til ca. 100 doser. Doseringsindretningen har en åbning til fyldning 30 eller genopfyldning af aktivt stof i den øvre del af magasinet. Åbningen lukkes fortrinsvis ved hjælp af en plastikprop 11.The size of the magazine can be selected to fit the expected requirements for a particular active substance. For example, in the metering device, the magazine may contain sufficient active substance for approx. 100 doses. The metering device has an opening for filling 30 or refilling active substance in the upper portion of the magazine. The opening is preferably closed by a plastic plug 11.
I en alternativ udførelsesform for doseringsindretningen er der en eftergivelig nøgle, som gør det muligt at udføre doseringen med kun 35 én hånd. Hvert tryk på nøglen bevirker en indexering af doseringsindretningen, således at en reces, der er fyldt med aktivt stof, placeres i forbindelse med udløbskanalen.In an alternative embodiment of the metering device, there is a resilient key which allows the metering to be performed with just one hand. Each press of the key causes an indexing of the dosing device so that a recess filled with active substance is placed in connection with the outlet duct.
Doseringsindretningen kan bruges som beholder og være til nytte ved 5The dosing device can be used as a container and be useful at 5
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dosering af et stort antal aktive stoffer, såsom enprophyllin, theophyllin og terbutalin.dosing a large number of active substances such as enprophylline, theophylline and terbutaline.
Den på nuværende tidspunkt bedste måde at udøve opfindelsen på er 5 vist på fig. 1.The best way of practicing the invention at present is shown in FIG. First
EksempelExample
Med henblik på at demonstrere doseringsnøjagtigheden af doserings-10 indretningen ifølge opfindelsen er følgende afprøvninger blevet udført med forskellige doseringsenheder med forskellige størrelser på recesserne A-G. Magasinet blev fyldt med Theo-Dur strøstof (som er et langsomt frigivet, mikroindkapslet præparat indeholdende theophyllin) blandet med 1 og 2% talkum. Når der etableredes en 15 doseringsnøjagtighed ud fra 500 doser, var den maksimale afvigelse 3,5%, jvf. tabellen nedenfor.In order to demonstrate the dosing accuracy of the dosing device of the invention, the following tests have been performed with different dosing units of different sizes on recesses A-G. The magazine was filled with Theo-Dur solids (which is a slow-release, microencapsulated preparation containing theophylline) mixed with 1 and 2% talc. When a dosing accuracy was established based on 500 doses, the maximum deviation was 3.5%, cf. the table below.
20 25 30 35 5 620 25 30 35 5 6
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Afprøvning med 7 forskellige doseringsenheder indeholdende Theo-Dur strøstof blandet med talkumTesting with 7 different dosage units containing Theo-Dur nitrogen mixed with talc
Tallene nedenfor er middelværdier af 500 doser fra hver doseringsenhed.The numbers below are averages of 500 doses from each dosage unit.
Doserings- Talkum 10 enhed 1% 2% mg/dosis srel % mg/dosis srel % A 104,1 2,15 2,1 104,2 2,45 2,4 15 B 94,0 2,36 2,5 94,0 2,66 2,8 C 85,4 2,29 2,7 84,8 2,30 2,7 D 73,2 2,45 3,3 75,1 1,73 2,3 E 64,7 1,68 2,6 64,5 2,02 3,1 F 54,3 1,33 2,5 53,4 1,87 3,5 20 G 45,8 1,34 2,9 45,9 1,30 2,8Dosage Talc 10 unit 1% 2% mg / dose srel% mg / dose srel% A 104.1 2.15 2.1 104.2 2.45 2.4 15 B 94.0 2.36 2.5 94 , 0. 2.66 2.8 C 85.4 2.29 2.7 84.8 2.30 2.7 D 73.2 2.45 3.3 75.1 1.73 2.3 E 64.7 1.68 2.6 64.5 2.02 3.1 F 54.3 1.33 2.5 53.4 1.87 3.5 20 G 45.8 1.34 2.9 45.9 1, 2.8
Til sammenligning henvises der til Pharm.Nord, som specificerer, at 90% af kapslerne skal indeholde en vægt, som ikke afviger mere end 25 10% fra den angivne vægt. Resten må ikke afvige mere end 20%. Med den nye doseringsindretning imødegås disse krav med rigelig margin.By comparison, reference is made to Pharm.Nord, which specifies that 90% of the capsules must contain a weight not exceeding 25 10% from the specified weight. The rest must not differ by more than 20%. With the new dosing device, these requirements are met with ample margin.
30 3530 35
Claims (10)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE8401796A SE8401796D0 (en) | 1984-04-02 | 1984-04-02 | dosing device |
| SE8401796 | 1984-04-02 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| DK135585D0 DK135585D0 (en) | 1985-03-26 |
| DK135585A DK135585A (en) | 1985-10-03 |
| DK162208B true DK162208B (en) | 1991-09-30 |
| DK162208C DK162208C (en) | 1992-03-16 |
Family
ID=20355391
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK135585A DK162208C (en) | 1984-04-02 | 1985-03-26 | DOSAGE DECOR |
Country Status (24)
| Country | Link |
|---|---|
| JP (1) | JPS60225564A (en) |
| KR (1) | KR920003127B1 (en) |
| AT (1) | AT392413B (en) |
| AU (1) | AU566240B2 (en) |
| BE (1) | BE902081A (en) |
| CA (1) | CA1304327C (en) |
| CH (1) | CH668639A5 (en) |
| DE (1) | DE3511817C2 (en) |
| DK (1) | DK162208C (en) |
| ES (1) | ES8603333A1 (en) |
| FI (1) | FI83032C (en) |
| FR (1) | FR2561912B1 (en) |
| GB (1) | GB2156783B (en) |
| GR (1) | GR850817B (en) |
| IE (1) | IE56449B1 (en) |
| IS (1) | IS1371B6 (en) |
| IT (1) | IT1181953B (en) |
| LU (1) | LU85828A1 (en) |
| NL (1) | NL192633C (en) |
| NO (1) | NO160129C (en) |
| NZ (1) | NZ211576A (en) |
| PT (1) | PT80205B (en) |
| SE (2) | SE8401796D0 (en) |
| ZA (1) | ZA851899B (en) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4021263C2 (en) * | 1990-07-04 | 1996-04-11 | Pfeiffer Erich Gmbh & Co Kg | Discharge device for media |
| US5280846A (en) * | 1992-09-23 | 1994-01-25 | Lonnecker Bruce R | Liquid and granular fluid dispenser |
| CN1045759C (en) * | 1993-09-22 | 1999-10-20 | 塞尼提克斯公司 | Indicator device responsive to axial force |
| US5654007A (en) * | 1995-06-07 | 1997-08-05 | Inhale Therapeutic Systems | Methods and system for processing dispersible fine powders |
| TW533865U (en) | 1997-06-10 | 2003-05-21 | Glaxo Group Ltd | Dispenser for dispensing medicament and actuation indicating device |
| KR101020774B1 (en) | 2008-11-27 | 2011-03-09 | 주식회사 삼화플라스틱 | A Medicine Case Drawing Out Dose |
| GB2554738A (en) | 2016-10-07 | 2018-04-11 | Res Center Pharmaceutical Engineering Gmbh | A system and a method for constant micro dosing and feeding of powder material |
| EP3376180B1 (en) * | 2017-03-14 | 2020-01-08 | Daneme Holding B.V. | Dispensing device for powders |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2088836A (en) * | 1936-09-24 | 1937-08-03 | Walter O Brown | Measuring container for granular material |
| US2901150A (en) * | 1954-04-26 | 1959-08-25 | Gustave O Matter | Measuring dispenser |
| DE1948180U (en) * | 1966-08-10 | 1966-10-20 | Kuma Rudolf Osterhold Kunststo | CAN WITH DOSING DEVICE FOR BREWABLE GOODS. |
| DE1956458U (en) * | 1966-12-13 | 1967-03-02 | Krups Fa Robert | HOUSEHOLD DOSING DEVICE FOR FOOD. |
| US3458091A (en) * | 1967-01-16 | 1969-07-29 | Carrol O Clement | Dispenser for powdered and granular material |
| DE2052051A1 (en) * | 1970-10-23 | 1972-04-27 | Steffens, Willi, 5208 Eitorf | Container with dosing device for free-flowing powdery to granular solids |
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1984
- 1984-04-02 SE SE8401796A patent/SE8401796D0/en unknown
-
1985
- 1985-03-08 SE SE8501129A patent/SE459781B/en not_active IP Right Cessation
- 1985-03-13 ZA ZA851899A patent/ZA851899B/en unknown
- 1985-03-15 GB GB08506731A patent/GB2156783B/en not_active Expired
- 1985-03-19 NL NL8500799A patent/NL192633C/en not_active IP Right Cessation
- 1985-03-20 IE IE714/85A patent/IE56449B1/en not_active IP Right Cessation
- 1985-03-21 NO NO851146A patent/NO160129C/en not_active IP Right Cessation
- 1985-03-25 CH CH1323/85A patent/CH668639A5/en not_active IP Right Cessation
- 1985-03-26 DK DK135585A patent/DK162208C/en not_active IP Right Cessation
- 1985-03-26 IT IT47873/85A patent/IT1181953B/en active
- 1985-03-26 AU AU40373/85A patent/AU566240B2/en not_active Expired
- 1985-03-26 CA CA000477460A patent/CA1304327C/en not_active Expired - Lifetime
- 1985-03-26 NZ NZ211576A patent/NZ211576A/en unknown
- 1985-03-29 KR KR1019850002097A patent/KR920003127B1/en not_active IP Right Cessation
- 1985-03-29 FR FR8504808A patent/FR2561912B1/en not_active Expired - Lifetime
- 1985-03-30 DE DE3511817A patent/DE3511817C2/en not_active Expired - Lifetime
- 1985-04-01 PT PT80205A patent/PT80205B/en unknown
- 1985-04-01 FI FI851302A patent/FI83032C/en not_active IP Right Cessation
- 1985-04-01 AT AT968/85A patent/AT392413B/en not_active IP Right Cessation
- 1985-04-01 BE BE0/214757A patent/BE902081A/en not_active IP Right Cessation
- 1985-04-01 LU LU85828A patent/LU85828A1/en unknown
- 1985-04-01 IS IS2996A patent/IS1371B6/en unknown
- 1985-04-01 ES ES541813A patent/ES8603333A1/en not_active Expired
- 1985-04-01 GR GR850817A patent/GR850817B/el unknown
- 1985-04-01 JP JP60066732A patent/JPS60225564A/en active Granted
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| PUP | Patent expired |