DK160500C - Analogifremgangsmaade til fremstilling af 3-thiomethylpyridinderivater - Google Patents

Analogifremgangsmaade til fremstilling af 3-thiomethylpyridinderivater

Info

Publication number
DK160500C
DK160500C DK188183A DK188183A DK160500C DK 160500 C DK160500 C DK 160500C DK 188183 A DK188183 A DK 188183A DK 188183 A DK188183 A DK 188183A DK 160500 C DK160500 C DK 160500C
Authority
DK
Denmark
Prior art keywords
group
preparation
optionally substituted
thiomethylpyridine
derivatives
Prior art date
Application number
DK188183A
Other languages
Danish (da)
English (en)
Other versions
DK188183D0 (da
DK160500B (da
DK188183A (da
Inventor
Helmut Schickaneder
Heidrun Engler
Istvan Szelenyi
Original Assignee
Heumann Ludwig & Co Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Heumann Ludwig & Co Gmbh filed Critical Heumann Ludwig & Co Gmbh
Publication of DK188183D0 publication Critical patent/DK188183D0/da
Publication of DK188183A publication Critical patent/DK188183A/da
Publication of DK160500B publication Critical patent/DK160500B/da
Application granted granted Critical
Publication of DK160500C publication Critical patent/DK160500C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/70Sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/10Expectorants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/32Sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
DK188183A 1982-05-05 1983-04-27 Analogifremgangsmaade til fremstilling af 3-thiomethylpyridinderivater DK160500C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3216843 1982-05-05
DE3216843A DE3216843C2 (de) 1982-05-05 1982-05-05 3-Thiomethyl-pyridin-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel

Publications (4)

Publication Number Publication Date
DK188183D0 DK188183D0 (da) 1983-04-27
DK188183A DK188183A (da) 1983-11-06
DK160500B DK160500B (da) 1991-03-18
DK160500C true DK160500C (da) 1991-08-26

Family

ID=6162790

Family Applications (1)

Application Number Title Priority Date Filing Date
DK188183A DK160500C (da) 1982-05-05 1983-04-27 Analogifremgangsmaade til fremstilling af 3-thiomethylpyridinderivater

Country Status (19)

Country Link
US (2) US4866066A (fr)
EP (1) EP0093252B1 (fr)
JP (1) JPS58203965A (fr)
KR (1) KR860001578B1 (fr)
AT (1) ATE32894T1 (fr)
AU (1) AU565518B2 (fr)
CA (1) CA1213279A (fr)
DD (1) DD208801A5 (fr)
DE (2) DE3216843C2 (fr)
DK (1) DK160500C (fr)
ES (1) ES520774A0 (fr)
GR (1) GR78961B (fr)
HU (1) HU189272B (fr)
IE (1) IE55263B1 (fr)
IL (1) IL68228A (fr)
MX (1) MX7122E (fr)
PT (1) PT76614B (fr)
YU (1) YU91483A (fr)
ZA (1) ZA832203B (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE25255T1 (de) * 1983-05-05 1987-02-15 Heumann Ludwig & Co Gmbh Pyrimidin-thioalkylpyridin-derivate, verfahren zu ihrer herstellung und diese verbindung enthaltende arzneimittel.
US4575554A (en) * 1983-12-05 1986-03-11 The Upjohn Company Substituted 2-pyridylmethylthio- and sulfinyl-benzimidazoles as gastric antisecretory agents
GB2161160B (en) * 1984-07-06 1989-05-24 Fisons Plc Heterocyclic sulphinyl compounds
DE3722810A1 (de) * 1987-07-10 1989-01-19 Hoechst Ag Substituierte benzimidazole, verfahren zu deren herstellung, diese enthaltende pharmazeutische zubereitungen und deren verwendung
BRPI0413324A (pt) 2003-08-06 2006-10-10 Senomyx Inc receptores de paladar hetero-oligoméricos t1r, linhas de células que expressam os ditos receptores, e compostos de paladar
US20060045953A1 (en) * 2004-08-06 2006-03-02 Catherine Tachdjian Aromatic amides and ureas and their uses as sweet and/or umami flavor modifiers, tastants and taste enhancers
TW200638882A (en) * 2005-02-04 2006-11-16 Senomyx Inc Molecules comprising linked organic moieties as flavor modifiers for comestible compositions
ZA200707482B (en) 2005-02-04 2008-12-31 Senomyx Inc Compounds comprising linked heteroaryl moieties and their use as novel umami flavour modifiers, tastants and taste enhancers for comestible compositions
AR055329A1 (es) * 2005-06-15 2007-08-15 Senomyx Inc Amidas bis-aromaticas y sus usos como modificadores de sabor dulce, saborizantes, y realzadores de sabor
WO2007124152A2 (fr) 2006-04-21 2007-11-01 Senomyx, Inc. Compositions comestibles comprenant des composes aromatisants a gout sale a potentiel eleve et leurs procedes de production

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1239017A (fr) * 1968-02-22 1971-07-14
GB1234058A (fr) * 1968-10-21 1971-06-03
GB1406882A (en) * 1972-04-28 1975-09-17 Leo Pharm Prod Ltd Benzoic acid derivatives and benzisptjoaup'e 1.1 dopxode derovatoves
GB1434405A (en) * 1973-09-06 1976-05-05 Leo Pharm Prod Ltd Phenyl-benzoic acid derivatives
SE418966B (sv) * 1974-02-18 1981-07-06 Haessle Ab Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan
SE416649B (sv) * 1974-05-16 1981-01-26 Haessle Ab Forfarande for framstellning av foreningar som paverkar magsyrasekretionen
JPS52125170A (en) * 1976-04-12 1977-10-20 Yoshitomi Pharmaceut Ind Ltd Pyridine derivatives
IT1092343B (it) * 1978-02-02 1985-07-06 Poli Ind Chimica Spa Pirimidilsolfuri ad attivita' antisecretoria,processo per la loro preparazione e composizioni farmaceutiche che li contengono
SE7804231L (sv) * 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
GB2038825B (en) * 1978-12-16 1983-02-09 Wyeth John & Brother Ltd Heterocyclic compounds substituted by heterocyclyl-alkyl-thio groups
GB2069493B (en) * 1980-02-20 1984-02-29 Wyeth John & Brother Ltd Pyridine derivatives
CH644116A5 (de) * 1980-08-21 1984-07-13 Hoffmann La Roche Imidazolderivate.
IL66340A (en) * 1981-08-13 1986-08-31 Haessle Ab Pharmaceutical compositions comprising pyridylmethyl-thiobenzimidazole derivatives,certain such novel derivatives and their preparation
US4546113A (en) * 1983-04-14 1985-10-08 Pfizer Inc. Antiprotozoal diamidines

Also Published As

Publication number Publication date
IE55263B1 (en) 1990-07-18
EP0093252B1 (fr) 1988-03-09
IE830976L (en) 1983-11-05
ES8401755A1 (es) 1984-01-01
ES520774A0 (es) 1984-01-01
DE3216843A1 (de) 1983-11-17
DK188183D0 (da) 1983-04-27
US4810715A (en) 1989-03-07
IL68228A (en) 1987-12-20
US4866066A (en) 1989-09-12
DE3216843C2 (de) 1986-10-23
GR78961B (fr) 1984-10-02
PT76614B (de) 1986-01-17
IL68228A0 (en) 1983-06-15
DK160500B (da) 1991-03-18
JPS58203965A (ja) 1983-11-28
AU565518B2 (en) 1987-09-17
EP0093252A3 (en) 1984-08-22
DD208801A5 (de) 1984-04-11
DE3375917D1 (en) 1988-04-14
YU91483A (en) 1986-02-28
MX7122E (es) 1987-06-29
PT76614A (de) 1983-05-01
KR860001578B1 (ko) 1986-10-10
KR840004076A (ko) 1984-10-06
DK188183A (da) 1983-11-06
ZA832203B (en) 1983-12-28
AU1264883A (en) 1983-11-10
ATE32894T1 (de) 1988-03-15
HU189272B (en) 1986-06-30
CA1213279A (fr) 1986-10-28
EP0093252A2 (fr) 1983-11-09

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