DK159456C - Analogifremgangsmaade til fremstilling af salte af cholsyrer, specielt chenodeoxycholsyre eller ursodeoxycholsyre, med 3,4,5-trimethoxybenzoesyreesteren af 2-phenyl-2-dimethylaminobutanol - Google Patents
Analogifremgangsmaade til fremstilling af salte af cholsyrer, specielt chenodeoxycholsyre eller ursodeoxycholsyre, med 3,4,5-trimethoxybenzoesyreesteren af 2-phenyl-2-dimethylaminobutanolInfo
- Publication number
- DK159456C DK159456C DK226882A DK226882A DK159456C DK 159456 C DK159456 C DK 159456C DK 226882 A DK226882 A DK 226882A DK 226882 A DK226882 A DK 226882A DK 159456 C DK159456 C DK 159456C
- Authority
- DK
- Denmark
- Prior art keywords
- acid
- unsodeoxycholic
- trimethoxybenzoese
- dimethylane
- estate
- Prior art date
Links
- RUDATBOHQWOJDD-UHFFFAOYSA-N (3beta,5beta,7alpha)-3,7-Dihydroxycholan-24-oic acid Natural products OC1CC2CC(O)CCC2(C)C2C1C1CCC(C(CCC(O)=O)C)C1(C)CC2 RUDATBOHQWOJDD-UHFFFAOYSA-N 0.000 title abstract 2
- 239000002812 cholic acid derivative Substances 0.000 title abstract 2
- 150000001842 cholic acids Chemical class 0.000 title abstract 2
- 239000002253 acid Substances 0.000 title 2
- RUDATBOHQWOJDD-BSWAIDMHSA-N chenodeoxycholic acid Chemical compound C([C@H]1C[C@H]2O)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(O)=O)C)[C@@]2(C)CC1 RUDATBOHQWOJDD-BSWAIDMHSA-N 0.000 title 1
- 229960001091 chenodeoxycholic acid Drugs 0.000 title 1
- 229950008352 promoxolane Drugs 0.000 title 1
- 235000019416 cholic acid Nutrition 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000000968 intestinal effect Effects 0.000 abstract 1
- 230000032297 kinesis Effects 0.000 abstract 1
- 238000010606 normalization Methods 0.000 abstract 1
- 230000000079 pharmacotherapeutic effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- RUDATBOHQWOJDD-UZVSRGJWSA-N ursodeoxycholic acid Chemical compound C([C@H]1C[C@@H]2O)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(O)=O)C)[C@@]2(C)CC1 RUDATBOHQWOJDD-UZVSRGJWSA-N 0.000 abstract 1
- 229960001661 ursodiol Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
- C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2186781 | 1981-05-21 | ||
| IT21867/81A IT1136624B (it) | 1981-05-21 | 1981-05-21 | Prodotti di salificazione di acidi colici,processo per la loro preparazione e composizioni terapeutiche che li comprendono come principio attivo |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK226882A DK226882A (da) | 1982-11-22 |
| DK159456B DK159456B (da) | 1990-10-15 |
| DK159456C true DK159456C (da) | 1991-03-18 |
Family
ID=11187975
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK226882A DK159456C (da) | 1981-05-21 | 1982-05-19 | Analogifremgangsmaade til fremstilling af salte af cholsyrer, specielt chenodeoxycholsyre eller ursodeoxycholsyre, med 3,4,5-trimethoxybenzoesyreesteren af 2-phenyl-2-dimethylaminobutanol |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US4404199A (ca) |
| EP (1) | EP0065666B1 (ca) |
| JP (1) | JPS57203098A (ca) |
| AT (1) | ATE11528T1 (ca) |
| CA (1) | CA1194469A (ca) |
| DE (1) | DE3262109D1 (ca) |
| DK (1) | DK159456C (ca) |
| ES (1) | ES8302735A1 (ca) |
| IE (1) | IE52917B1 (ca) |
| IT (1) | IT1136624B (ca) |
| NO (1) | NO158423C (ca) |
| PT (1) | PT74864B (ca) |
| YU (1) | YU43516B (ca) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1152801B (it) * | 1982-08-17 | 1987-01-14 | Proter Spa | Composti steroidei ad attivita' coleretica, processo per la loro preparazione e composizioni terapeutiche che li contengono come principio attivo |
| US5753269A (en) * | 1995-12-27 | 1998-05-19 | Bayer Corporation | Otic microbial combinations |
| IL139241A0 (en) | 1998-05-13 | 2001-11-25 | Novo Nordisk As | Meiosis regulating compounds |
| US20020119921A1 (en) * | 1999-03-31 | 2002-08-29 | Michael Streit | Thrombospondin-2 and uses thereof |
| AU2001231196A1 (en) * | 2000-01-27 | 2001-08-07 | The General Hospital Corporation | Delivery of therapeutic biological from implantable tissue matrices |
| CA3194562C (en) | 2014-07-29 | 2026-03-17 | Shenzhen Hightide Biopharmaceutical, Ltd. | Berberine-ursodeoxycholic salt, method of preparation and application therof |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2369M (fr) * | 1962-10-17 | 1964-03-02 | Jouveinal Lab | Nouveau médicament contre les troubles du systeme nerveux central. |
| GB1532413A (en) * | 1974-12-23 | 1978-11-15 | Union International Co Ltd | Chenodeoxycholic acid |
| GB1431709A (en) * | 1973-12-03 | 1976-04-14 | Prodotti Antibiotici Spa | Lysozyme derivatives |
| FR2358144A1 (fr) * | 1976-07-13 | 1978-02-10 | Lipha | Nouvelle composition medicamenteuse pour le traitement de la lithiase biliaire |
| US4186143A (en) * | 1977-06-20 | 1980-01-29 | Canada Packers Limited | Chenodeoxycholic acid recovery process |
| JPS5529075A (en) * | 1978-08-24 | 1980-03-01 | Suzuki Motor Co Ltd | Crank room oil recoverer for 2-cycle engine |
| US4241047A (en) * | 1979-07-18 | 1980-12-23 | Lipha, Lyonnaise Industrielle Pharmaceutique | Novel medicinal composition for the treatment of biliary lithiasis |
-
1981
- 1981-05-21 IT IT21867/81A patent/IT1136624B/it active
-
1982
- 1982-04-30 AT AT82103701T patent/ATE11528T1/de not_active IP Right Cessation
- 1982-04-30 EP EP82103701A patent/EP0065666B1/en not_active Expired
- 1982-04-30 DE DE8282103701T patent/DE3262109D1/de not_active Expired
- 1982-05-03 US US06/374,243 patent/US4404199A/en not_active Expired - Fee Related
- 1982-05-04 IE IE1056/82A patent/IE52917B1/en not_active IP Right Cessation
- 1982-05-05 CA CA000402296A patent/CA1194469A/en not_active Expired
- 1982-05-10 PT PT74864A patent/PT74864B/pt unknown
- 1982-05-19 DK DK226882A patent/DK159456C/da not_active IP Right Cessation
- 1982-05-19 YU YU1065/82A patent/YU43516B/xx unknown
- 1982-05-19 NO NO821672A patent/NO158423C/no unknown
- 1982-05-20 ES ES512391A patent/ES8302735A1/es not_active Expired
- 1982-05-21 JP JP57085079A patent/JPS57203098A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| YU43516B (en) | 1989-08-31 |
| EP0065666A1 (en) | 1982-12-01 |
| NO158423B (no) | 1988-05-30 |
| IE52917B1 (en) | 1988-04-13 |
| US4404199A (en) | 1983-09-13 |
| PT74864B (fr) | 1983-12-07 |
| YU106582A (en) | 1984-10-31 |
| ATE11528T1 (de) | 1985-02-15 |
| DK159456B (da) | 1990-10-15 |
| PT74864A (fr) | 1982-06-01 |
| JPS57203098A (en) | 1982-12-13 |
| NO158423C (no) | 1988-09-14 |
| DE3262109D1 (en) | 1985-03-14 |
| IE821056L (en) | 1982-11-21 |
| IT1136624B (it) | 1986-09-03 |
| CA1194469A (en) | 1985-10-01 |
| ES512391A0 (es) | 1983-02-01 |
| DK226882A (da) | 1982-11-22 |
| IT8121867A0 (it) | 1981-05-21 |
| JPS6312478B2 (ca) | 1988-03-18 |
| NO821672L (no) | 1982-11-22 |
| EP0065666B1 (en) | 1985-01-30 |
| ES8302735A1 (es) | 1983-02-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PBP | Patent lapsed |