DE69314570D1 - Verfahren zur Herstellung Taurin-konjugierter Gallensäure - Google Patents

Verfahren zur Herstellung Taurin-konjugierter Gallensäure

Info

Publication number
DE69314570D1
DE69314570D1 DE69314570T DE69314570T DE69314570D1 DE 69314570 D1 DE69314570 D1 DE 69314570D1 DE 69314570 T DE69314570 T DE 69314570T DE 69314570 T DE69314570 T DE 69314570T DE 69314570 D1 DE69314570 D1 DE 69314570D1
Authority
DE
Germany
Prior art keywords
taurine
preparation
bile acid
alpha
conjugated bile
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69314570T
Other languages
English (en)
Inventor
Antonio Bonaldi
Egidio Molinari
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Erregierre Industria Chimica SpA
Original Assignee
Erregierre Industria Chimica SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11363834&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69314570(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Erregierre Industria Chimica SpA filed Critical Erregierre Industria Chimica SpA
Application granted granted Critical
Publication of DE69314570D1 publication Critical patent/DE69314570D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0055—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives
    • C07J41/0061—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives one of the carbon atoms being part of an amide group

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE69314570T 1992-08-04 1993-07-28 Verfahren zur Herstellung Taurin-konjugierter Gallensäure Expired - Lifetime DE69314570D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI921925A IT1255486B (it) 1992-08-04 1992-08-04 Processo per preparare gli acidi biliari coniugati con la taurina

Publications (1)

Publication Number Publication Date
DE69314570D1 true DE69314570D1 (de) 1997-11-20

Family

ID=11363834

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69314570T Expired - Lifetime DE69314570D1 (de) 1992-08-04 1993-07-28 Verfahren zur Herstellung Taurin-konjugierter Gallensäure

Country Status (7)

Country Link
US (1) US5362891A (de)
EP (1) EP0582891B1 (de)
JP (1) JPH06157584A (de)
AT (1) ATE159259T1 (de)
CA (1) CA2101381A1 (de)
DE (1) DE69314570D1 (de)
IT (1) IT1255486B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20020028876A (ko) * 1999-04-30 2002-04-17 추후제출 스테로이드 유도체
US20070197484A1 (en) * 2001-05-03 2007-08-23 Ching Song Method of treating disorder related to high cholesterol concentration
US7078396B2 (en) * 2001-05-03 2006-07-18 Arch Development Corporation Method of treating disorder related to high cholesterol concentration
WO2002090375A2 (en) * 2001-05-03 2002-11-14 The University Of Chicago Liver x receptor agonists
WO2003086303A2 (en) * 2002-04-12 2003-10-23 The University Of Chicago Farnesoid x-activated receptor agonists
US20070032464A1 (en) * 2004-10-08 2007-02-08 Shutsung Liao Methods of treating cancers
EP1985622A1 (de) * 2007-04-23 2008-10-29 Prodotti Chimici E Alimentari Spa Verfahren zur Herstellung von Tauroursodesoxycholsäure
JP2013500986A (ja) * 2009-07-29 2013-01-10 ザ・ユニバーシティ・オブ・シカゴ 肝臓ｘ受容体アゴニスト
CN102453070B (zh) * 2010-10-26 2013-08-28 四川科伦药物研究有限公司 一种猪磺去氧胆酸ⅱ型晶体及其制备方法
CN105330715B (zh) * 2016-01-04 2018-07-06 杭州和泽医药科技有限公司 一种牛磺熊去氧胆酸的制备方法
US9598357B1 (en) * 2016-02-29 2017-03-21 Vitaworks Ip, Llc Process for producing taurine from alkali taurinates
IT201900005906A1 (it) * 2019-04-16 2020-10-16 Dipharma Francis Srl Procedimento di preparazione di coniugati di un acido colanico
CN114195852A (zh) * 2021-12-28 2022-03-18 中山百灵生物技术股份有限公司 一种3β,7β-二羟基-5β-胆烷酸的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3622669A (en) * 1967-10-23 1971-11-23 Merck & Co Inc 5{62 -taurocholenic acids and 5{62 -taurocholadienic acids in compositions for reducing the concentration of cholesterol and liads in blood serum
CA1173823A (en) * 1980-08-26 1984-09-04 Leonard M. Hjelmeland Nondenaturing zwitterionic detergent for membrane biochemistry
IT1206112B (it) * 1983-04-29 1989-04-14 Lehner Ag Nuovi derivati di acidi biliari, procedimento per la loro preparazione e relative composizioni farmaceutiche.
IT1230796B (it) * 1989-05-30 1991-10-29 Prodotti Chimici Alimentari Procedimento per la preparazione di acido tauroursodesossicolico biidrato.

Also Published As

Publication number Publication date
IT1255486B (it) 1995-11-06
ITMI921925A0 (it) 1992-08-04
EP0582891B1 (de) 1997-10-15
ATE159259T1 (de) 1997-11-15
ITMI921925A1 (it) 1994-02-04
EP0582891A2 (de) 1994-02-16
US5362891A (en) 1994-11-08
CA2101381A1 (en) 1994-02-05
JPH06157584A (ja) 1994-06-03
EP0582891A3 (de) 1995-03-15

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Legal Events

Date Code Title Description
8332 No legal effect for de