DK1569680T3 - Behandling af diabetes - Google Patents
Behandling af diabetesInfo
- Publication number
- DK1569680T3 DK1569680T3 DK03774936T DK03774936T DK1569680T3 DK 1569680 T3 DK1569680 T3 DK 1569680T3 DK 03774936 T DK03774936 T DK 03774936T DK 03774936 T DK03774936 T DK 03774936T DK 1569680 T3 DK1569680 T3 DK 1569680T3
- Authority
- DK
- Denmark
- Prior art keywords
- methods
- diabetes
- treatment
- gastin
- complement
- Prior art date
Links
- 206010012601 diabetes mellitus Diseases 0.000 title 1
- 238000000034 method Methods 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 102000004859 Cholecystokinin Receptors Human genes 0.000 abstract 1
- 108090001085 Cholecystokinin Receptors Proteins 0.000 abstract 1
- 230000000295 complement effect Effects 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 239000003446 ligand Substances 0.000 abstract 1
- 230000009707 neogenesis Effects 0.000 abstract 1
- 210000000056 organ Anatomy 0.000 abstract 1
- 238000013268 sustained release Methods 0.000 abstract 1
- 239000012730 sustained-release form Substances 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
- A61K38/1796—Receptors; Cell surface antigens; Cell surface determinants for hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/37—Digestive system
- A61K35/39—Pancreas; Islets of Langerhans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/2278—Vasoactive intestinal peptide [VIP]; Related peptides (e.g. Exendin)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/27—Growth hormone [GH], i.e. somatotropin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
- A61L27/3687—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the use of chemical agents in the treatment, e.g. specific enzymes, detergents, capping agents, crosslinkers, anticalcification agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
- A61L27/3695—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the function or physical properties of the final product, where no specific conditions are defined to achieve this
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/595—Gastrins; Cholecystokinins [CCK]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Endocrinology (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Cell Biology (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- General Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Botany (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Emergency Medicine (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Genetics & Genomics (AREA)
- Nutrition Science (AREA)
- Virology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US42018702P | 2002-10-22 | 2002-10-22 | |
US42039902P | 2002-10-22 | 2002-10-22 | |
US42810002P | 2002-11-21 | 2002-11-21 | |
US42856202P | 2002-11-22 | 2002-11-22 | |
PCT/US2003/033595 WO2004037195A2 (en) | 2002-10-22 | 2003-10-22 | Treatment of diabetes |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1569680T3 true DK1569680T3 (da) | 2009-05-18 |
Family
ID=32180693
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK03774936T DK1569680T3 (da) | 2002-10-22 | 2003-10-22 | Behandling af diabetes |
Country Status (15)
Country | Link |
---|---|
US (3) | US20060189520A1 (de) |
EP (2) | EP1569680B1 (de) |
JP (1) | JP2006506386A (de) |
KR (1) | KR20050074492A (de) |
AT (1) | ATE421333T1 (de) |
AU (1) | AU2003283004A1 (de) |
BR (1) | BR0315523A (de) |
CA (1) | CA2501677A1 (de) |
DE (1) | DE60326002D1 (de) |
DK (1) | DK1569680T3 (de) |
ES (1) | ES2320754T3 (de) |
MX (1) | MXPA05004202A (de) |
NO (1) | NO20052419L (de) |
PL (1) | PL376473A1 (de) |
WO (1) | WO2004037195A2 (de) |
Families Citing this family (72)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6558952B1 (en) * | 1992-12-14 | 2003-05-06 | Waratah Pharmaceuticals, Inc. | Treatment for diabetes |
GB9409496D0 (en) * | 1994-05-12 | 1994-06-29 | London Health Ass | Method for improving glycaemic control in diabetes |
US20050272652A1 (en) | 1999-03-29 | 2005-12-08 | Gault Victor A | Peptide analogues of GIP for treatment of diabetes, insulin resistance and obesity |
ATE411077T1 (de) | 2001-01-12 | 2008-10-15 | Waratah Pharmaceuticals Inc | Zusammensetzungen, welche gastrin/cck- rezeptorligande und egf-rezeptorligande enthalten,zur induzierung der neogenese von inselzellen |
US7037504B2 (en) * | 2001-10-23 | 2006-05-02 | Waratah Pharmaceuticals, Inc. | Epidermal growth factor protein and gene, and methods of use therefor |
IL165242A0 (en) * | 2002-05-24 | 2005-12-18 | Waratah Pharmaceuticals Inc | Treatment for diabetes |
ES2334268T3 (es) | 2002-06-07 | 2010-03-08 | Waratah Pharmaceuticals, Inc. | Procedimientos y composiciones para el tratamiento de la diabetes. |
EP1837031B1 (de) | 2002-06-07 | 2009-10-14 | Waratah Pharmaceuticals, Inc. | Methoden und Kompositionen um Diabetes zu behandeln |
EP1569680B1 (de) * | 2002-10-22 | 2009-01-21 | Waratah Pharmaceuticals, Inc. | Behandlung von diabetes. |
US20040229810A1 (en) * | 2002-10-22 | 2004-11-18 | Antonio Cruz | Gastrin compositions and formulations, and methods of use and preparation |
US7731947B2 (en) | 2003-11-17 | 2010-06-08 | Intarcia Therapeutics, Inc. | Composition and dosage form comprising an interferon particle formulation and suspending vehicle |
EP1617888B1 (de) | 2003-04-23 | 2019-06-12 | Valeritas, Inc. | Hydraulisch aktivierte pumpe für langzeitabgabe von medikamenten |
US20080039379A1 (en) * | 2003-05-27 | 2008-02-14 | Waratah Pharmaceuticals, Inc. | Compositions Comprising Gastrin Compounds and Their Use in Diabetes |
RU2005140518A (ru) * | 2003-05-27 | 2007-07-10 | Уэйрейта Фармасьютиклз, Инк. (Ca) | Композиции и способы, включающие соединения гастрина |
EP1684824B1 (de) | 2003-11-20 | 2015-08-12 | The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. | Tragbare handpumpe zur evakuierung von flüssigkeiten |
EP1711532A4 (de) * | 2004-01-30 | 2009-09-16 | Waratah Pharmaceuticals Inc | Kombinierte anwendung eines glp-1-agonisten mit gastrinverbindungen |
US8076288B2 (en) | 2004-02-11 | 2011-12-13 | Amylin Pharmaceuticals, Inc. | Hybrid polypeptides having glucose lowering activity |
WO2006000567A2 (en) * | 2004-06-28 | 2006-01-05 | Novo Nordisk A/S | Use of glp-1 receptor agonists and / or dpp-iv inhibitors in combination with proton pump inhibitors and ppar agonists for the preparation of a medicament for the treatment of diabetes type i i and impaired pancreatic beta-cell function |
EP1765873A4 (de) * | 2004-07-01 | 2009-07-01 | Waratah Pharmaceuticals Inc | Verfahren und zusammensetzungen unter anwendung von cd3-agonisten |
WO2006014425A1 (en) | 2004-07-02 | 2006-02-09 | Biovalve Technologies, Inc. | Methods and devices for delivering glp-1 and uses thereof |
US8361976B2 (en) | 2004-07-09 | 2013-01-29 | University Of Massachusetts | Therapeutic alteration of transplantable tissues through in situ or ex vivo exposure to RNA interference molecules |
US8337475B2 (en) | 2004-10-12 | 2012-12-25 | C. R. Bard, Inc. | Corporeal drainage system |
US11246913B2 (en) | 2005-02-03 | 2022-02-15 | Intarcia Therapeutics, Inc. | Suspension formulation comprising an insulinotropic peptide |
WO2006083761A2 (en) | 2005-02-03 | 2006-08-10 | Alza Corporation | Solvent/polymer solutions as suspension vehicles |
SG159551A1 (en) | 2005-02-11 | 2010-03-30 | Amylin Pharmaceuticals Inc | Gip analog and hybrid polypeptides with selectable properties |
US8263545B2 (en) | 2005-02-11 | 2012-09-11 | Amylin Pharmaceuticals, Inc. | GIP analog and hybrid polypeptides with selectable properties |
WO2007019522A2 (en) * | 2005-08-04 | 2007-02-15 | Carlos Lopez | Reversal of adult onset disorders with granulocyte-colony stimulating factors |
WO2007038643A1 (en) | 2005-09-26 | 2007-04-05 | C.R. Bard, Inc. | Catheter connection systems |
CN101365476A (zh) * | 2005-10-07 | 2009-02-11 | 瓦拉塔药品公司 | Dpp-iv抑制剂和胃泌素化合物的联合使用 |
US20070100322A1 (en) * | 2005-10-31 | 2007-05-03 | Ramakrishna Venugopalan | Method of removing a stylette from a catheter |
US20090162345A1 (en) * | 2005-11-29 | 2009-06-25 | Atkinson Mark A | Materials and Methods for Reversing Type-1 Diabetes |
WO2007095737A1 (en) * | 2006-02-21 | 2007-08-30 | Waratah Pharmaceuticals Inc. | Combination therapy for the treatment of diabetes comprising an exendin agonist and a gastrin compound |
JP2009527504A (ja) * | 2006-02-23 | 2009-07-30 | イオメディックス スリープ インターナショナル エスアールエル | 良質な睡眠の誘導および維持のための組成物および方法 |
ES2656675T3 (es) | 2006-03-30 | 2018-02-28 | Valeritas, Inc. | Dispositivo de suministro de fluidos de múltiples cartuchos |
MX2008014870A (es) | 2006-05-30 | 2009-02-12 | Intarcia Therapeutics Inc | Modulador de flujo para sistema de suministro osmotico con canal interno de dos piezas. |
EP2359808B1 (de) * | 2006-08-09 | 2013-05-22 | Intarcia Therapeutics, Inc | Osmotisches Verabreichungssystem mit Kolbenanordnung |
US8497240B2 (en) | 2006-08-17 | 2013-07-30 | Amylin Pharmaceuticals, Llc | DPP-IV resistant GIP hybrid polypeptides with selectable properties |
CN105688191A (zh) | 2007-04-23 | 2016-06-22 | 精达制药公司 | 促胰岛素释放肽的混悬制剂及其应用 |
US20090324609A1 (en) | 2007-08-09 | 2009-12-31 | Genzyme Corporation | Method of treating autoimmune disease with mesenchymal stem cells |
WO2009046015A2 (en) * | 2007-09-30 | 2009-04-09 | University Of Florida Research Foundation, Inc. | Combination therapies for treating type 1 diabetes |
WO2009102467A2 (en) | 2008-02-13 | 2009-08-20 | Intarcia Therapeutics, Inc. | Devices, formulations, and methods for delivery of multiple beneficial agents |
DE102008023820A1 (de) * | 2008-05-08 | 2009-11-12 | Aicuris Gmbh & Co. Kg | Mittel zur Behandlung und/oder Prophylaxe einer Autoimmunerkrankung und zur Bildung von Regulatorischen T-Zellen |
US8697098B2 (en) | 2011-02-25 | 2014-04-15 | South Dakota State University | Polymer conjugated protein micelles |
US8512737B1 (en) * | 2008-06-03 | 2013-08-20 | Abbott Cardiovascular Systems Inc. | Embolic delivery of therapeutic agents |
EP2318433A4 (de) | 2008-08-07 | 2012-08-08 | Ipsen Pharma Sas | Am n-terminus modifizierte analoga des glucoseabhängigen insulinotropen polypeptids (gip) |
KR20130133104A (ko) | 2008-08-07 | 2013-12-05 | 입센 파마 에스.에이.에스 | 포도당 의존적인 인슐린 분비 자극성 폴리펩타이드 유사체 |
CA2738715C (en) * | 2008-10-15 | 2013-07-16 | Intarcia Therapeutics, Inc. | Highly concentrated drug particles, formulations, suspensions and uses thereof |
US8821872B2 (en) * | 2009-05-01 | 2014-09-02 | Jill P. Smith | Identification and characterization of a specific CCK-C receptor antibody for human pancreatic cancer and its use for early detection and staging of pancreatic cancer |
US8383671B1 (en) | 2009-06-18 | 2013-02-26 | Abbott Cardiovascular Systems Inc. | Method of treating malignant solid tumors |
MX352878B (es) | 2009-09-28 | 2017-12-13 | Intarcia Therapeutics Inc | Establecimiento y/o terminacion rapidos de suministro de estado estable sustancial de farmaco. |
US9539324B2 (en) | 2010-12-01 | 2017-01-10 | Alderbio Holdings, Llc | Methods of preventing inflammation and treating pain using anti-NGF compositions |
US8911734B2 (en) | 2010-12-01 | 2014-12-16 | Alderbio Holdings Llc | Methods of preventing or treating pain using anti-NGF antibodies that selectively inhibit the association of NGF with TrkA, without affecting the association of NGF with p75 |
US9067988B2 (en) | 2010-12-01 | 2015-06-30 | Alderbio Holdings Llc | Methods of preventing or treating pain using anti-NGF antibodies |
US11214610B2 (en) | 2010-12-01 | 2022-01-04 | H. Lundbeck A/S | High-purity production of multi-subunit proteins such as antibodies in transformed microbes such as Pichia pastoris |
US9078878B2 (en) | 2010-12-01 | 2015-07-14 | Alderbio Holdings Llc | Anti-NGF antibodies that selectively inhibit the association of NGF with TrkA, without affecting the association of NGF with p75 |
US9884909B2 (en) | 2010-12-01 | 2018-02-06 | Alderbio Holdings Llc | Anti-NGF compositions and use thereof |
US20120208755A1 (en) | 2011-02-16 | 2012-08-16 | Intarcia Therapeutics, Inc. | Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers |
EP2678001B1 (de) | 2011-02-25 | 2017-04-05 | South Dakota State University | Polymerkonjugierte protein-micellen |
MX364643B (es) * | 2011-08-03 | 2019-05-03 | Ma Zhongmin | USO DEL COMPUESTO FTY720: 2-amino - 2-[2-(4-octilfenil) etil] propano-1,3-diol (fingolimod) EN EL TRATAMIENTO DE PACIENTES CON DIABETES DE TIPO 2. |
GB201304038D0 (en) * | 2013-03-06 | 2013-04-17 | Nhs Blood & Transplant | Treated cells and therapeutic uses |
BR102013017626A2 (pt) * | 2013-06-14 | 2015-02-10 | Univ Rio De Janeiro | Bioconjugados não aglomerantes de amilinomiméticos com polietilenoglicol, uso de bioconjugados não aglomerantes de amilinomiméticos com polietilenoglicol, composições farmacêuticas de baixa toxicidade, adjuvante para a prevenção ou tratamento das doenças, medicamento, método de tratamento ou prevenção de doenças. |
US9889085B1 (en) | 2014-09-30 | 2018-02-13 | Intarcia Therapeutics, Inc. | Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c |
JP6993235B2 (ja) | 2015-06-03 | 2022-01-13 | インターシア セラピューティクス,インコーポレイティド | インプラントの設置及び撤去システム |
JP2019505535A (ja) * | 2016-02-05 | 2019-02-28 | エントレガ,インコーポレイテッド | 活性剤の送達のための乾燥剤を含む経口製剤 |
EP3458084B1 (de) | 2016-05-16 | 2020-04-01 | Intarcia Therapeutics, Inc | Für den glucagonrezeptor selektive polypeptide und verfahren zu deren verwendung |
USD860451S1 (en) | 2016-06-02 | 2019-09-17 | Intarcia Therapeutics, Inc. | Implant removal tool |
USD840030S1 (en) | 2016-06-02 | 2019-02-05 | Intarcia Therapeutics, Inc. | Implant placement guide |
KR20190104039A (ko) | 2017-01-03 | 2019-09-05 | 인타르시아 세라퓨틱스 인코포레이티드 | Glp-1 수용체 효능제의 연속적인 투여 및 약물의 동시-투여를 포함하는 방법 |
KR20230031981A (ko) | 2019-05-14 | 2023-03-07 | 프로벤션 바이오, 인코포레이티드 | 제1형 당뇨병을 예방하기 위한 방법 및 조성물 |
CN113106054B (zh) * | 2020-01-13 | 2022-10-14 | 青岛瑞思德生物科技有限公司 | 一种将间充质干细胞诱导分化为胰岛细胞的诱导剂 |
CN111394311B (zh) * | 2020-04-20 | 2022-07-01 | 青岛瑞思德生物科技有限公司 | 一种诱导间充质干细胞向角膜上皮细胞分化的无血清完全培养基 |
AU2021287998A1 (en) | 2020-06-11 | 2023-02-02 | Benaroya Research Institute At Virginia Mason | Methods and compositions for preventing type 1 diabetes |
Family Cites Families (71)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3451974A (en) * | 1965-12-01 | 1969-06-24 | Du Pont | Process for moisture conditioning of nylon |
US3487139A (en) * | 1967-05-25 | 1969-12-30 | Mojonnier Inc Albert | Method of forming plastic articles |
US4289817A (en) * | 1970-09-14 | 1981-09-15 | Valyi Emery I | Decorated multilayered hollow plastic container |
US4421712A (en) * | 1980-08-13 | 1983-12-20 | Maryland Cup Corporation | Continuously rotary thermo-forming systems and apparatus of the pressure assist, plug assist and match mold type |
US4393373A (en) | 1981-03-16 | 1983-07-12 | Fuji Electrochemical Co., Ltd. | Piezoelectric audible sound generator |
JPS6028994A (ja) * | 1983-07-08 | 1985-02-14 | Wakunaga Seiyaku Kk | 〔21―ロイシン〕ヒトウロガストロン |
US4686283A (en) | 1985-04-16 | 1987-08-11 | Syntex (U.S.A.) Inc. | Analogs of transforming and epidermal growth factor fragments for therapy and diagnosis |
US5614492A (en) * | 1986-05-05 | 1997-03-25 | The General Hospital Corporation | Insulinotropic hormone GLP-1 (7-36) and uses thereof |
US5120712A (en) * | 1986-05-05 | 1992-06-09 | The General Hospital Corporation | Insulinotropic hormone |
US5554386A (en) | 1986-07-03 | 1996-09-10 | Advanced Magnetics, Inc. | Delivery of therapeutic agents to receptors using polysaccharides |
EP0441889A1 (de) | 1988-11-07 | 1991-08-21 | Commission des Communautés Européennes | Modifiziertes menschliches wachstumshormon |
ES2063912T3 (es) * | 1989-01-24 | 1995-01-16 | Aphton Corp | Composiciones inmunogenicas frente a peptidos de gastrina. |
US4997950A (en) * | 1989-04-20 | 1991-03-05 | Richard Finbar Murphy | Novel C-terminal gastrin antagonists |
US5158935A (en) * | 1989-05-12 | 1992-10-27 | Chiron Corporation | Human epidermal growth factor having substitution at position 11 |
US5128242A (en) | 1989-06-19 | 1992-07-07 | The Administrators Of The Tulane Educational Fund | Hypothalamic polypeptides with adenylate cyclase stimulating activity |
US5198542A (en) | 1989-06-20 | 1993-03-30 | Takeda Chemical Industries, Inc. | Dna encoding a pitvitary adenylate cyclase activating protein and use thereof |
US5362716A (en) * | 1989-12-27 | 1994-11-08 | The United States Of America As Represented By The Department Of Health And Human Services | Methods for stimulating hematopoietic progenitors using hepatocyte growth factor and lymphokines |
US5545618A (en) * | 1990-01-24 | 1996-08-13 | Buckley; Douglas I. | GLP-1 analogs useful for diabetes treatment |
EP0467279A3 (en) | 1990-07-18 | 1992-08-05 | Takeda Chemical Industries, Ltd. | Polypeptides having c-amp producing activity |
EP0586549B1 (de) * | 1991-05-10 | 2000-09-20 | Genentech, Inc. | Auswählen von agonisten und antagonisten von liganden |
WO1993003757A1 (en) | 1991-08-16 | 1993-03-04 | Chiron Corporation | Muteins of epidermal growth factor exhibiting enhanced binding at low ph |
DK36392D0 (da) * | 1992-03-19 | 1992-03-19 | Novo Nordisk As | Anvendelse af kemisk forbindelse |
NZ314299A (en) * | 1992-08-11 | 1998-08-26 | E | Containers formed from a hydraulically settable mixture including a binder, a rheology-modifying agent, fibres and water |
US6558952B1 (en) * | 1992-12-14 | 2003-05-06 | Waratah Pharmaceuticals, Inc. | Treatment for diabetes |
US5885956A (en) | 1992-12-14 | 1999-03-23 | Research Triangle Pharmaceuticals | Treatment for diabetes using a gastrin/CCK receptor ligand and an EGF receptor ligand |
US6284727B1 (en) * | 1993-04-07 | 2001-09-04 | Scios, Inc. | Prolonged delivery of peptides |
CA2121192A1 (en) | 1993-04-21 | 1994-10-22 | Kiminori Atsumi | Collagen membranes |
US5424286A (en) * | 1993-05-24 | 1995-06-13 | Eng; John | Exendin-3 and exendin-4 polypeptides, and pharmaceutical compositions comprising same |
US5773569A (en) | 1993-11-19 | 1998-06-30 | Affymax Technologies N.V. | Compounds and peptides that bind to the erythropoietin receptor |
US5705483A (en) * | 1993-12-09 | 1998-01-06 | Eli Lilly And Company | Glucagon-like insulinotropic peptides, compositions and methods |
US6001647A (en) * | 1994-04-28 | 1999-12-14 | Ixion Biotechnology, Inc. | In vitro growth of functional islets of Langerhans and in vivo uses thereof |
US5587309A (en) * | 1994-04-29 | 1996-12-24 | The United States Of America As Represented By The Department Of Health And Human Services | Method of stimulating proliferation and differentiation of human fetal pancreatic cells ex vivo |
WO1995029690A1 (en) * | 1994-04-29 | 1995-11-09 | The Trustees Of The University Of Pennsylvania | Biologically active peptides and methods of identifying the same |
GB9409496D0 (en) * | 1994-05-12 | 1994-06-29 | London Health Ass | Method for improving glycaemic control in diabetes |
US5885574A (en) | 1994-07-26 | 1999-03-23 | Amgen Inc. | Antibodies which activate an erythropoietin receptor |
US5993850A (en) * | 1994-09-13 | 1999-11-30 | Skyepharma Inc. | Preparation of multivesicular liposomes for controlled release of encapsulated biologically active substances |
US5512549A (en) * | 1994-10-18 | 1996-04-30 | Eli Lilly And Company | Glucagon-like insulinotropic peptide analogs, compositions, and methods of use |
US20010006943A1 (en) * | 1994-12-23 | 2001-07-05 | Ejvind Jensen | Protracted GLP-1 compositions |
US6458764B1 (en) * | 1995-05-26 | 2002-10-01 | Theratechnologies Inc. | GRF analogs with increased biological potency |
AU6163196A (en) | 1995-06-07 | 1996-12-30 | Smithkline Beecham Corporation | Method for obtaining receptor agonist antibodies |
US5766620A (en) * | 1995-10-23 | 1998-06-16 | Theratech, Inc. | Buccal delivery of glucagon-like insulinotropic peptides |
US6346390B1 (en) * | 1996-03-08 | 2002-02-12 | Receptron, Inc. | Receptor derived peptides involved in modulation of response to ligand binding |
ATE417622T1 (de) * | 1996-08-08 | 2009-01-15 | Amylin Pharmaceuticals Inc | Regulation gastrointestinaler beweglichkeit |
US6956026B2 (en) * | 1997-01-07 | 2005-10-18 | Amylin Pharmaceuticals, Inc. | Use of exendins for the reduction of food intake |
US6268343B1 (en) * | 1996-08-30 | 2001-07-31 | Novo Nordisk A/S | Derivatives of GLP-1 analogs |
US6458924B2 (en) * | 1996-08-30 | 2002-10-01 | Novo Nordisk A/S | Derivatives of GLP-1 analogs |
UA65549C2 (uk) * | 1996-11-05 | 2004-04-15 | Елі Ліллі Енд Компані | Спосіб регулювання ожиріння шляхом периферійного введення аналогів та похідних glp-1 (варіанти) та фармацевтична композиція |
US6011155A (en) * | 1996-11-07 | 2000-01-04 | Novartis Ag | N-(substituted glycyl)-2-cyanopyrrolidines, pharmaceutical compositions containing them and their use in inhibiting dipeptidyl peptidase-IV |
JP2001521897A (ja) | 1997-10-31 | 2001-11-13 | スミスクライン・ビーチャム・コーポレイション | 新規な金属錯体 |
FR2770843B1 (fr) | 1997-11-13 | 2000-01-14 | Lavipharm Lab | Association prolamines-lipides polaires vegetaux, son procede de preparation et ses applications |
JP2001525371A (ja) * | 1997-12-05 | 2001-12-11 | イーライ・リリー・アンド・カンパニー | Glp−1製剤 |
EP1056775B1 (de) * | 1998-02-27 | 2010-04-28 | Novo Nordisk A/S | Derivate von glp-1 und exendin mit verlängertem wirkdauer-profil |
US20020127254A1 (en) | 1998-06-25 | 2002-09-12 | Lavipharm Laboratories Inc. | Devices for local and systemic delivery of active substance and methods of manufacturing thereof |
US6242563B1 (en) | 1998-07-20 | 2001-06-05 | Societe De Conseils De Recherches Et D'applications Scientifiques, Sas | Peptide analogues |
WO2000007617A1 (en) * | 1998-07-31 | 2000-02-17 | Novo Nordisk A/S | Use of glp-1 and analogues for preventing type ii diabetes |
AU2153500A (en) | 1998-11-19 | 2000-06-05 | Millennium Pharmaceuticals, Inc. | Egf-like nucleic acids and polypeptides and uses thereof |
DE60044041D1 (de) * | 1999-01-14 | 2010-04-29 | Amylin Pharmaceuticals Inc | Exendine zur Glucagon Suppression |
ES2244416T5 (es) * | 1999-01-14 | 2020-01-03 | Amylin Pharmaceuticals Llc | Formulaciones novedosas de agonistas de la exendina y métodos de administración de los mismos |
US6451974B1 (en) * | 1999-03-17 | 2002-09-17 | Novo Nordisk A/S | Method of acylating peptides and novel acylating agents |
US6514500B1 (en) * | 1999-10-15 | 2003-02-04 | Conjuchem, Inc. | Long lasting synthetic glucagon like peptide {GLP-!} |
US6506724B1 (en) * | 1999-06-01 | 2003-01-14 | Amylin Pharmaceuticals, Inc. | Use of exendins and agonists thereof for the treatment of gestational diabetes mellitus |
WO2001039784A1 (en) * | 1999-12-06 | 2001-06-07 | The General Hospital Corporation | Pancreatic stem cells and their use in transplantation |
US6967100B2 (en) * | 2000-02-18 | 2005-11-22 | The Walter And Eliza Hall Institute Of Medical Research | Pancreatic islet cell growth factors |
PT2055302E (pt) * | 2000-03-31 | 2014-12-03 | Royalty Pharma Collection Trust | Processo para a melhoria da sinalização de ilhéus em diabetes mellitus e para a sua prevenção |
ATE411077T1 (de) * | 2001-01-12 | 2008-10-15 | Waratah Pharmaceuticals Inc | Zusammensetzungen, welche gastrin/cck- rezeptorligande und egf-rezeptorligande enthalten,zur induzierung der neogenese von inselzellen |
CA2442177A1 (en) * | 2001-03-29 | 2002-10-10 | Ixion Biotechnology, Inc. | Method for transdifferentiation of non-pancreatic stem cells to the pancreatic differentiation pathway |
WO2002096203A1 (en) * | 2001-05-25 | 2002-12-05 | Cythera, Inc. | Stem cell differentiation |
AU2002316811A1 (en) * | 2001-06-28 | 2003-03-03 | Novo Nordisk A/S | Stable formulation of modified glp-1 |
US7037504B2 (en) * | 2001-10-23 | 2006-05-02 | Waratah Pharmaceuticals, Inc. | Epidermal growth factor protein and gene, and methods of use therefor |
GB2399823B (en) * | 2001-12-07 | 2006-02-15 | Geron Corp | Islet cells from primate pluripotent stem cells |
EP1569680B1 (de) * | 2002-10-22 | 2009-01-21 | Waratah Pharmaceuticals, Inc. | Behandlung von diabetes. |
-
2003
- 2003-10-22 EP EP03774936A patent/EP1569680B1/de not_active Expired - Lifetime
- 2003-10-22 ES ES03774936T patent/ES2320754T3/es not_active Expired - Lifetime
- 2003-10-22 DK DK03774936T patent/DK1569680T3/da active
- 2003-10-22 MX MXPA05004202A patent/MXPA05004202A/es active IP Right Grant
- 2003-10-22 WO PCT/US2003/033595 patent/WO2004037195A2/en active Application Filing
- 2003-10-22 EP EP08021849A patent/EP2080521A1/de not_active Withdrawn
- 2003-10-22 US US10/532,295 patent/US20060189520A1/en not_active Abandoned
- 2003-10-22 DE DE60326002T patent/DE60326002D1/de not_active Expired - Lifetime
- 2003-10-22 AT AT03774936T patent/ATE421333T1/de active
- 2003-10-22 PL PL03376473A patent/PL376473A1/xx unknown
- 2003-10-22 CA CA002501677A patent/CA2501677A1/en not_active Abandoned
- 2003-10-22 JP JP2004547077A patent/JP2006506386A/ja active Pending
- 2003-10-22 BR BR0315523-4A patent/BR0315523A/pt not_active Application Discontinuation
- 2003-10-22 AU AU2003283004A patent/AU2003283004A1/en not_active Abandoned
- 2003-10-22 US US10/691,123 patent/US20040209801A1/en not_active Abandoned
- 2003-10-22 KR KR1020057006825A patent/KR20050074492A/ko not_active Application Discontinuation
-
2005
- 2005-05-19 NO NO20052419A patent/NO20052419L/no not_active Application Discontinuation
-
2008
- 2008-10-16 US US12/252,814 patent/US20090036381A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
JP2006506386A (ja) | 2006-02-23 |
CA2501677A1 (en) | 2004-05-06 |
WO2004037195A3 (en) | 2005-06-16 |
NO20052419L (no) | 2005-07-07 |
US20090036381A1 (en) | 2009-02-05 |
EP1569680B1 (de) | 2009-01-21 |
ATE421333T1 (de) | 2009-02-15 |
EP2080521A1 (de) | 2009-07-22 |
EP1569680A2 (de) | 2005-09-07 |
MXPA05004202A (es) | 2005-09-20 |
US20060189520A1 (en) | 2006-08-24 |
DE60326002D1 (de) | 2009-03-12 |
NO20052419D0 (no) | 2005-05-19 |
US20040209801A1 (en) | 2004-10-21 |
WO2004037195A2 (en) | 2004-05-06 |
AU2003283004A1 (en) | 2004-05-13 |
PL376473A1 (en) | 2005-12-27 |
BR0315523A (pt) | 2005-08-30 |
KR20050074492A (ko) | 2005-07-18 |
ES2320754T3 (es) | 2009-05-28 |
EP1569680A4 (de) | 2006-05-17 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK1569680T3 (da) | Behandling af diabetes | |
DE60329724D1 (de) | Methoden und Kompositionen um Diabetes zu behandeln | |
CY1118731T1 (el) | Φαρμακευτικες συνθεσεις αλβιγλουτιδης | |
ECSP067095A (es) | Compuestos y metodos para el tratamiento de dislipidemia | |
DK1734971T3 (da) | Indretning på polymerbasis med forsinket frigivelse | |
ATE412387T1 (de) | Medizinische vorrichtungen | |
BR0207871A (pt) | Composição para liberar bisfosfonato para um alvo | |
AR052774A1 (es) | Inmunoterapia para trastornos autoinmunes | |
BRPI0417717A (pt) | composto, composição farmacêutica, e, uso de um composto | |
NO20065368L (no) | Terapeutiske blandinger inneholdende minst et pyrrolobenzodiazepinderivat og fludarabin | |
NO20071914L (no) | Kontrollert avleveringssystem | |
ECSP067062A (es) | Derivados de pirazol, composiciones que contienen dichos compuestos y procedimientos de uso | |
NO20052512L (no) | Purinforbindelser og anvendelse deav som kannabinoiode reseptorligander | |
AR057946A1 (es) | Formulacion de zonisamida de liberacion sostenidda | |
GT200500119A (es) | Derivados de tetraazabenzo [e] azuleno y sus analogos | |
DE602005018178D1 (de) | Phospholipid und verunreinigungsbeständige beschichtungszusammensetzungen | |
ECSP055726A (es) | Composición farmacéutica estabilizada que contiene excipientes básicos | |
MX2010006204A (es) | Derivados de oxindol 5,6-disubstituidos y el uso de los mismos para el tratamiento de enfermedades dependientes de la vasopresina. | |
DK1864668T3 (da) | Anvendelse af prodrug til okulær, intravitreal administration | |
DK1749517T3 (da) | Stabil farmaceutiske sammensætning af linezolid form IV | |
ECSP044981A (es) | Composicion oftalmica que comprende ascomicina | |
CY1114480T1 (el) | Συνθεσεις που περιλαμβανουν διαχωρισμενο αγωνιστη υποδοχεα γλυκοκορτικοειδους για τη θεραπεια ή τον ελεγχο φλεγμονης προσθιου τμηματος | |
BRPI0500536A (pt) | Composição antimicrobiana | |
ATE539155T1 (de) | Targets und zusammensetzungen zur therapeutischen intervention bei hiv-infektion | |
FI20030779A0 (fi) | Matriisinauha |