DK1567653T3 - Recombinant koppevirus, som omfatter i det mindste to kokoppe ATI promoterer - Google Patents
Recombinant koppevirus, som omfatter i det mindste to kokoppe ATI promotererInfo
- Publication number
- DK1567653T3 DK1567653T3 DK03789029T DK03789029T DK1567653T3 DK 1567653 T3 DK1567653 T3 DK 1567653T3 DK 03789029 T DK03789029 T DK 03789029T DK 03789029 T DK03789029 T DK 03789029T DK 1567653 T3 DK1567653 T3 DK 1567653T3
- Authority
- DK
- Denmark
- Prior art keywords
- coconut
- seq
- ati
- smallpox virus
- recombinant
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
- C12N15/863—Poxviral vectors, e.g. entomopoxvirus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/275—Poxviridae, e.g. avipoxvirus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
- C12N2710/24141—Use of virus, viral particle or viral elements as a vector
- C12N2710/24143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/60—Vector systems having a special element relevant for transcription from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2840/00—Vectors comprising a special translation-regulating system
- C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron
- C12N2840/203—Vectors comprising a special translation-regulating system translation of more than one cistron having an IRES
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- AIDS & HIV (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DKPA200201814 | 2002-11-25 | ||
PCT/EP2003/012610 WO2004048582A2 (fr) | 2002-11-25 | 2003-11-12 | Poxvirus de recombinaison comprenant au moins deux promoteurs ati de la vaccine |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1567653T3 true DK1567653T3 (da) | 2007-10-15 |
Family
ID=32337938
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK03789029T DK1567653T3 (da) | 2002-11-25 | 2003-11-12 | Recombinant koppevirus, som omfatter i det mindste to kokoppe ATI promoterer |
Country Status (21)
Country | Link |
---|---|
US (1) | US7300658B2 (fr) |
EP (1) | EP1567653B1 (fr) |
JP (1) | JP2006515170A (fr) |
KR (1) | KR20050083839A (fr) |
CN (1) | CN1717488A (fr) |
AT (1) | ATE365220T1 (fr) |
AU (1) | AU2003293675B2 (fr) |
CA (1) | CA2501168A1 (fr) |
CY (1) | CY1106883T1 (fr) |
DE (1) | DE60314541T2 (fr) |
DK (1) | DK1567653T3 (fr) |
EA (1) | EA012723B1 (fr) |
ES (1) | ES2288634T3 (fr) |
IL (1) | IL167844A (fr) |
MX (1) | MXPA05005549A (fr) |
NO (1) | NO20053125D0 (fr) |
NZ (1) | NZ540156A (fr) |
PL (1) | PL375740A1 (fr) |
PT (1) | PT1567653E (fr) |
UA (1) | UA85379C2 (fr) |
WO (1) | WO2004048582A2 (fr) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2256323T5 (es) * | 2000-11-23 | 2016-11-21 | Bavarian Nordic A/S | Variante del virus Vaccinia Ankara Modificado |
US7501127B2 (en) | 2002-05-16 | 2009-03-10 | Bavarian Nordic A/S | Intergenic regions as novel sites for insertion of HIV DNA sequences in the genome of Modified Vaccinia virus Ankara |
CA2481521C (fr) * | 2002-05-16 | 2012-04-17 | Bavarian Nordic A/S | Regions intergeniques utilisees comme sites d'insertion dans le genome du virus de la vaccine ankara modifie (mva) |
WO2008100292A2 (fr) | 2006-10-16 | 2008-08-21 | Genelux Corporation | Souches du virus de la vaccine modifié pour une utilisation dans des procédés diagnostiques et thérapeutiques |
US20110052627A1 (en) * | 2008-06-20 | 2011-03-03 | Paul Chaplin | Recombinant modified vaccinia virus measles vaccine |
CN106318978B (zh) * | 2008-11-21 | 2020-06-23 | 巴法里安诺迪克有限公司 | 包含多个同源核苷酸序列的载体 |
US8394385B2 (en) * | 2009-03-13 | 2013-03-12 | Bavarian Nordic A/S | Optimized early-late promoter combined with repeated vaccination favors cytotoxic T cell response against recombinant antigen in MVA vaccines |
US9567331B2 (en) | 2011-11-15 | 2017-02-14 | Trustees Of Boston University | Pyridopyrimidinone inhibitors of viruses |
EP3244919A4 (fr) * | 2015-01-12 | 2018-06-27 | Geovax, Inc. | Compositions et procédés de génération d'une réponse immunitaire à un virus responsable des fièvres hémorragiques |
KR20160140075A (ko) | 2015-05-29 | 2016-12-07 | 코오롱생명과학 주식회사 | 폭스바이러스 유래 프로모터 및 이를 포함하는 벡터 |
FR3042121A1 (fr) | 2015-10-08 | 2017-04-14 | Jean-Marc Limacher | Composition anti-tumorale |
ES2939617T3 (es) * | 2015-11-24 | 2023-04-25 | Glaxosmithkline Ip Dev Ltd | Líneas celulares estables para producción retroviral |
FR3044017B1 (fr) * | 2015-11-24 | 2019-05-03 | Glaxosmithkline Intellectual Property Development Limited | Procede de transfection transitoire pour la production retrovirale |
CN109071592B (zh) | 2016-01-08 | 2022-07-19 | 吉奥瓦科斯公司 | 用于产生对肿瘤相关抗原的免疫应答的组合物和方法 |
WO2017136419A1 (fr) | 2016-02-03 | 2017-08-10 | Geovax Inc. | Compositions et procédés de génération d'une réponse immunitaire à un flavivirus |
WO2018031694A1 (fr) * | 2016-08-09 | 2018-02-15 | City Of Hope | Compositions de poxvirus chimériques et leurs utilisations |
US11311612B2 (en) | 2017-09-19 | 2022-04-26 | Geovax, Inc. | Compositions and methods for generating an immune response to treat or prevent malaria |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5443964A (en) * | 1987-08-10 | 1995-08-22 | Duke University | Poxvirus insertion/expression vector |
US5759841A (en) * | 1990-11-20 | 1998-06-02 | Virogenetics Corporation | Immunological composition of measles virus utilizing recombinant poxvirus |
UA68327C2 (en) * | 1995-07-04 | 2004-08-16 | Gsf Forschungszentrum Fur Unwe | A recombinant mva virus, an isolated eukaryotic cell, infected with recombinant mva virus, a method for production in vitro of polypeptides with use of said cell, a method for production in vitro of virus parts (variants), vaccine containing the recombinant mva virus, a method for immunization of animals |
WO1998013500A2 (fr) * | 1996-09-24 | 1998-04-02 | Bavarian Nordic Research Institute A/S | Virus mva de recombinaison exprimant des antigenes du virus de dengue et utilisation de ces derniers dans des vaccins |
WO2000073476A1 (fr) * | 1999-05-28 | 2000-12-07 | Gsf Forschungszentrum Für Umwelt Und Gesundheit Gmbh | Vecteur d'integration de sequences heterologues dans des genomes de poxvirus |
AU9322201A (en) | 2000-08-29 | 2002-03-13 | American Cyanamid Co | Packaging of positive-strand rna virus replicon particles |
-
2003
- 2003-11-12 DE DE60314541T patent/DE60314541T2/de not_active Expired - Lifetime
- 2003-11-12 EP EP03789029A patent/EP1567653B1/fr not_active Expired - Lifetime
- 2003-11-12 JP JP2004554335A patent/JP2006515170A/ja active Pending
- 2003-11-12 ES ES03789029T patent/ES2288634T3/es not_active Expired - Lifetime
- 2003-11-12 DK DK03789029T patent/DK1567653T3/da active
- 2003-11-12 UA UAA200506292A patent/UA85379C2/ru unknown
- 2003-11-12 MX MXPA05005549A patent/MXPA05005549A/es active IP Right Grant
- 2003-11-12 AT AT03789029T patent/ATE365220T1/de active
- 2003-11-12 PL PL03375740A patent/PL375740A1/xx not_active Application Discontinuation
- 2003-11-12 CA CA002501168A patent/CA2501168A1/fr not_active Abandoned
- 2003-11-12 EA EA200500879A patent/EA012723B1/ru not_active IP Right Cessation
- 2003-11-12 AU AU2003293675A patent/AU2003293675B2/en not_active Ceased
- 2003-11-12 CN CNA2003801040985A patent/CN1717488A/zh active Pending
- 2003-11-12 US US10/535,371 patent/US7300658B2/en not_active Expired - Fee Related
- 2003-11-12 KR KR1020057007295A patent/KR20050083839A/ko active IP Right Grant
- 2003-11-12 PT PT03789029T patent/PT1567653E/pt unknown
- 2003-11-12 WO PCT/EP2003/012610 patent/WO2004048582A2/fr active IP Right Grant
- 2003-11-12 NZ NZ540156A patent/NZ540156A/en not_active IP Right Cessation
-
2005
- 2005-04-04 IL IL167844A patent/IL167844A/en not_active IP Right Cessation
- 2005-06-24 NO NO20053125A patent/NO20053125D0/no not_active Application Discontinuation
-
2007
- 2007-09-20 CY CY20071101220T patent/CY1106883T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
ES2288634T3 (es) | 2008-01-16 |
AU2003293675A1 (en) | 2004-06-18 |
CY1106883T1 (el) | 2012-09-26 |
ATE365220T1 (de) | 2007-07-15 |
PT1567653E (pt) | 2007-10-01 |
DE60314541D1 (de) | 2007-08-02 |
AU2003293675B2 (en) | 2009-04-23 |
KR20050083839A (ko) | 2005-08-26 |
DE60314541T2 (de) | 2008-02-28 |
US20060153874A1 (en) | 2006-07-13 |
EP1567653B1 (fr) | 2007-06-20 |
NO20053125L (no) | 2005-06-24 |
IL167844A (en) | 2011-03-31 |
EP1567653A2 (fr) | 2005-08-31 |
WO2004048582A2 (fr) | 2004-06-10 |
EA200500879A1 (ru) | 2005-10-27 |
CN1717488A (zh) | 2006-01-04 |
CA2501168A1 (fr) | 2004-06-10 |
US7300658B2 (en) | 2007-11-27 |
WO2004048582A3 (fr) | 2004-08-12 |
MXPA05005549A (es) | 2005-08-16 |
PL375740A1 (en) | 2005-12-12 |
JP2006515170A (ja) | 2006-05-25 |
EA012723B1 (ru) | 2009-12-30 |
UA85379C2 (ru) | 2009-01-26 |
NZ540156A (en) | 2006-11-30 |
NO20053125D0 (no) | 2005-06-24 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO20053125D0 (no) | Rekombinant koppevirus omfattende i det minste to kukoppe-ati-promotere. | |
HK1076835A1 (en) | Expression of genes in modified vaccinia virus ankara by using the cowpox ati promoter | |
ES2256323T3 (es) | Variante del virus vaccinia ankara modificado. | |
UA82998C2 (ru) | Экспрессия генов в модифицированном вирусе коровьей оспы ankara с использованием коровьего поксвирусного промотора аті | |
US6869793B2 (en) | Recombinant MVA virus expressing dengue virus antigens, and the use thereof in vaccines | |
WO2001089559A3 (fr) | Vaccin a poxvirus recombinant contre le virus du syndrome disgenesique respiratoire porcin (vsdrp) | |
CN101142319B (zh) | 基于使用修饰安卡拉痘苗病毒的疫苗 | |
WO2003023040A3 (fr) | Mutants du virus de la vaccine obtenus par inactivation de mva-e3l et leur utilisation | |
EP1855720B2 (fr) | Utilisation d'un virus de la variole modifié pour l'induction rapide d'une immunité contre un virus de la variole ou d'autres agents infectieux | |
BR0012512A (pt) | Genes de calicivìrus felino e vacinas notadamente vacinas recombinadas | |
UA84667C2 (ru) | Вакцина, направленная против инфекции, вызванной вирусом герпеса болезни марека | |
WO2003040305A3 (fr) | Regions e1 et e4 d'adenovirus porcin | |
CA2430115A1 (fr) | Systemes d'expression de virus rsv de recombinaison et vaccins | |
CA2372709A1 (fr) | Vecteur d'integration de sequences heterologues dans des genomes de poxvirus | |
BRPI0416916A (pt) | promotores para expressão em vìrus de vacìnia modificada ankara | |
DK1356062T3 (da) | Frembringelse af rekombinanter af kunstigt gærkromosom af human cytomegalovirus | |
NZ512341A (en) | Polynucleotides between 15 and 100 base pairs in length coding for parapoxvirus ovis (PPVO)/vaccinia virus recombinant (VVOV) viral genome fragments | |
JP2009232836A5 (fr) | ||
MX2023006688A (es) | Eliminacion genomica en la vacuna contra la peste porcina africana que permite un crecimiento eficaz en estirpes celulares estables. | |
CA2351010A1 (fr) | Vaccin a large spectre d'efficacite contre le virus de la bursite infectieuse | |
BR0316553A (pt) | Poxvìrus recombinante que compreende pelo menos dois promotores ati de varìola bovina | |
RU2023132190A (ru) | Новые последовательности белков и нуклеиновых кислот для вакцин против covid-19 | |
DK200201813A (da) | Ekspression af gener i modificeret vaccinia virus ankara ved brug af ATI promotoren fra ko-kopper | |
Cheng et al. | 106 Gln Glu Glu 122 Met Met Val |